Clinical trials: sponsored by Turku University Hospital
Bone Metastases, Bone Neoplasm
Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases
The FURTHER study aims to evaluate the effectiveness and cost-effectiveness of MR-HIFU (alone or in combination with EBRT) compared to EBRT alone, the standard-of-care, as a palliative treatment option to relieve CIBP.
- Conditions
- Bone Metastases, Bone Neoplasm, Bone Lesion, Bone Cancer
- Trial name
- FURTHER (NCT04307914)
- Testing
- External beam radiotherapy, MR-HIFU
- Where
- 6 sites in Finland, Germany and 2 more
- Volunteers
- 216 people
- Sponsor
- UMC Utrecht
Sensorineural Hearing Loss, Bilateral
Quantifying the Benefits and Cost-effectiveness of Real-Ear Measurements (REM) for Hearing Aid Fitting
Adjusting hearing aid user's real ear performance by using probe-microphone technology (real ear measurement, REM) has been a well-known procedure that verifies whether the output of the hearing aid at the eardrum matches the…
- Trial name
- BREM (NCT05621798)
- Testing
- Hearing Aid Manufacturer's Software, REM (Real Ear Measurements)
- Where
- Finland
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Stroke Acute
Fusion Imaging in Endovascular Thrombectomy for Acute Ischemic Stroke
Endovascular thrombectomy (EVT) is the standard of care for acute ischemic stroke (AIS) caused by a large vessel occlusion. Successful recanalization is one of the most important factors for a good patient outcome, especially…
- Trial name
- FUSE-IT (NCT06975696)
- Testing
- Standard endovascular thrombectomy with Fusion, Standard EVT without Fusion
- Where
- 4 sites in Finland, Sweden
- Volunteers
- 300 people
- Sponsor
- Region Skane
Glioblastoma
Supramarginal Resection in Glioblastoma
Gliomas are the most common malignant brain tumor. Glioblastoma, WHO grade IV astrocytoma, is the most common subtype and unfortunately also the most aggressive subtype with median survival in population based cohorts being only…
- Trial name
- NCT04243005
- Testing
- Supramarginal resection, Conventional surgery
- Where
- 17 sites in Austria, Denmark and 4 more
- Volunteers
- 90 people
- Sponsor
- St. Olavs Hospital
Hearing Disorders and Deafness
ListenFuture-Listening for Their Future: Deaf and Hard-of-Hearing Adolescents
ListenFuture, a nation-wide multidisciplinary project, brings new knowledge on complex associations between listening, cognition, language, literacy, and psychosocial wellbeing in deaf and hard-of-hearing (DHH) adolescents.
- Trial name
- ListenFuture (NCT07416292)
- Where
- 7 sites in Finland
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Heikki Löppönen
Influenza Vaccination
Administration of the Nasal Influenza Vaccine to Children in Daycare or at a Healthcare Facility
The goal of this intervention study is to learn if giving children influenza vaccinations in early childhood education facilities (i.e., daycare) will increase vaccination coverage compared to giving vaccinations only at…
- Trial name
- NCT07310472
- Testing
- Possibility to get live attenuated nasal influenza vaccine at daycare
- Where
- Finland
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Cardiac Arrest
The Association Between Technical and Non-technical Skills in Real-life ALS Situations. Impact of Pit Crew Model on the Resuscitation Skills.
Cardiac arrest is handled by cardiopulmonary resuscitation which is a time critical emergency situation. The actions during resuscitation are lead by international guidelines.
- Trial name
- NCT03017144
- Testing
- Pit crew model education
- Volunteers
- 36 people
- Sponsor
- Turku University Hospital
Colorectal Neoplasms
Randomized Trial Comparing Fecal Testing (FIT) to Colonoscopy for Post-polypectomy Surveillance
From observational studies, it is know that the risk of developing colorectal cancer after polyp removal is lower if the patients adheres to surveillance recommendations.
- Trial name
- NCT06983639
- Testing
- Fecal occult blood testing, Colonoscopy
- Where
- Norway
- Volunteers
- 4,000 people
- Sponsor
- Sorlandet Hospital HF
Prematurity
Preterm Neonates Brain Ultrasound With CEUS and Elastography
The aim of the study is to investigate levels of brain perfusion and elasticity in preterm neonates when they reach the estimated due date and to compare the data with magnetic resonance imaging at term.
- Trial name
- NCT05694611
- Testing
- Brain contrast enhanced ultrasound, brain ultrasound elastography, Sulfur Hexafluoride
- Where
- Finland
- Sponsor
- Turku University Hospital
Neonatal Hypoxic Ischemic Encephalopathy, Neonatal Stroke
Neonatal Brain Ultrasound With CEUS and Elastography
The aim of our study is to investigate changes of brain perfusion and elasticity in neonates during the time that a neonate is adapting to live outside the womb and during diseases that are suspected to affect neonatal brain…
- Conditions
- Neonatal Hypoxic Ischemic Encephalopathy, Neonatal Stroke, Neonatal Encephalopathy, Unspecified
- Trial name
- NCT05648812
- Testing
- Brain contrast enhanced ultrasound, brain ultrasound elastography, Sulfur Hexafluoride
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Turku University Hospital
Testicular Diseases
Thermal Imaging in the Diagnosis of Acute Testicular Pain
Acute scrotal pain due to testicular torsion is a rare but urgent urological condition that requires immediate surgery to prevent permanent damage or loss of the testicle.
- Trial name
- NCT07324590
- Testing
- Thermidas thermal camera
- Where
- Finland
- Volunteers
- 150 people
- Sponsor
- Seinajoki Central Hospital
Coronary Artery Disease, Brain Injury
Neuroprotective Effect of Mild Hypothermia Versus Normothermia During Cardiopulmonary Bypass of Coronary Artery Surgery
In high-income countries, coronary artery bypass grafting (CABG) remains a common procedure, with approximately 36.7 operations per 100,000 inhabitants annually, corresponding to about 136,000 procedures in the European Union.
- Trial name
- HYPNOCABG (NCT07316868)
- Testing
- Normothermic cardiopulmonary bypass, Hypothermic cardiopulmonary bypass
- Where
- Finland
- Volunteers
- 160 people
- Sponsor
- Turku University Hospital
Preterm Infant Development, Preterm Infant Health
Pilot Study: Effects of CCP Intervention on NICU Environment and Preterm Infants Development
Close Collaboration with Parents intervention is an evidence-based educational intervention for the entire multi-professional staff of neonatal intensive care units (NICUs).
- Trial name
- NCT07306000
- Testing
- Close Collaboration with Parents training
- Where
- 3 sites in Japan, South Korea
- Volunteers
- 100 people
- Sponsor
- Turku University Hospital
Obesity, Obesity & Overweight
Interaction of Sleep, Diurnal Eating Pattern, Gut Microbiota, and Obesity
The goals of the proposed study are 1) to provide scientific basis for the relationship between subjective sleep quality, diurnal eating pattern, gut microbiome, and obesity, 2) to develop and test a pragmatic, cost-effective new…
- Trial name
- ObeApp (NCT04850391)
- Testing
- Mobile app
- Where
- Finland
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
COPD
Open-Label Prospective Study Comparing Long-Term Outcome With or Without HFNC in Patients With Stable Hypercapnic COPD
The aims of the study are to compare long-term one-year outcome with or without AirvoTM in stabile hypercapnic COPD patients, who are non-compliant to NIV after an acute exacerbation of COPD.
- Trial name
- MyAirvo (NCT04840706)
- Testing
- HFNC Airvo, Standard care
- Where
- Finland
- Volunteers
- 3 people
- Sponsor
- Turku University Hospital
Pregnancy, Postpartum
Usability Study of Gestational and Postpartum Weight Management Program
The principal aim of this study is to evaluate the usability of the Hope-D gestational and 6 months postpartum weight management program.
- Conditions
- Pregnancy, Postpartum, Obese Pregnant Women, Weight Management
- Trial name
- Hope-D_Use (NCT07272824)
- Where
- Finland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Labor, Induced, Labor, Obstetric
Maternal Informing on Labor Induction: Impact on Childbirth Experience
The aim of this study is to explore the information provided to mothers about labor induction and its connection to their childbirth experience.
- Conditions
- Labor, Induced, Labor, Obstetric, Pregnancy, Humans
- Trial name
- NCT07272785
- Where
- Finland
- Volunteers
- 50 people
- Sponsor
- Turku University Hospital
Persistent Physical Symptoms (PPS), Functional Disorder
The Pilot of the Turku Outpatient Clinic for Functional and Fatigue Disorders
This study examined 125 working-age patients from the Turku Outpatient Clinic for Functional and Fatigue Disorders. "Patients participate in the clinic's biopsychosocial, multidisciplinary, and individually tailored…
- Conditions
- Persistent Physical Symptoms (PPS), Functional Disorder, Fatigue Syndrome, Chronic
- Trial name
- TOCliFFD (NCT07272148)
- Testing
- Biopsychosocial, multidisciplinary, and individually tailored rehabilitation for patients with persisten symptoms
- Where
- Finland
- Volunteers
- 125 people
- Sponsor
- Turku University Hospital
Colon Cancer
Colon Cancer Diagnosis With FAPI-PET Imaging
Whole body CT is the primary imaging method in staging and follow-up of colon cancer. Conventional PET-CT with 18F-labeled fluorodeoxyglucose (18F-FDG) has its limitations and has a secondary role in colon cancer protocols.
- Trial name
- NCT07272772
- Testing
- PET/CT ([F-18]FAPI-74)
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Turku University Hospital
Pregnancy in Diabetic, Diabetes Mellitus, Type 1
Noninvasive Evaluation of Fetal Hyperinsulinemia With Ultrasound Radiomics
The goal of this observational study is to compare fetal liver ultrasound radiomics between pregnancies complicated by type 1 diabetes and healthy controls.
- Trial name
- NCT06343974
- Where
- 2 sites in Finland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital