Clinical trials: sponsored by The Cleveland Clinic
Warming Systems During Surgery
A Randomized Comparison of Intraoperative Warming With the LMA PerfecTemp and Forced-air
Recently, a novel posterior heating system has been developed that provides enhanced pressure relief: the Laryngeal Mask Airway (LMA) PerfecTemp.
- Trial name
- NCT01094119
- Testing
- heated blanket, heated pad
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The Cleveland Clinic
Impaired Airway Clearance
Fospropofol for Sedation During Elective Awake Intubation
Patients scheduled for awake fiberoptic intubation (AFI) because of potential difficult airway will be consented prior to intubation ASA Physical Status classification and history of difficult intubation will be recorded at…
- Trial name
- NCT01289483
- Testing
- fospropofol
- Where
- United States
- Sponsor
- The Cleveland Clinic
Migraine Headache
Electrical Stimulation of the Sphenopalatine Ganglion for the Treatment of Migraine Headaches
This investigation will gather information about a procedure called sphenopalatine ganglion (SPG) stimulation, and its appropriateness, safety, and efficacy as a treatment for those who suffer migraine headaches which may result…
- Trial name
- NCT01294046
- Testing
- Deep Brain Stimulation of SPG for Migraine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The Cleveland Clinic
Obesity
Evaluation of High-Density Lipoprotein in Obesity Study
Obesity is associated with an impaired functioning HDL (good cholesterol) resulting in an acceleration in the development of atherosclerosis.
- Trial name
- NCT00912236
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- The Cleveland Clinic
Non-cardiac Surgery
Evaluating Heat Transfer With the Esophageal Cooling Device
An esophageal heat exchange tube will be inserted in anesthetized surgical patients. Each patient will have 30 minutes of cooling (circulating fluid at 7 degrees C) and 30 minutes of warming (42 degrees C) with 15-minute recovery…
- Trial name
- NCT02743884
- Testing
- Esophageal Warming, Esophageal Cooling
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- The Cleveland Clinic
Parkinson's Disease, Depression
rTMS for Motor and Mood Symptoms of Parkinson's Disease
The purpose of this study is to determine if repetitive transcranial magnetic stimulation (rTMS), a method of noninvasive brain stimulation) is effective in the treatment of the motor (movement) and mood symptoms due to…
- Trial name
- MASTER-PD (NCT01080794)
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- 6 sites in United States, Canada
- Volunteers
- 61 people
- Sponsor
- Beth Israel Deaconess Medical Center
Sacroiliac Injection
a Diagnostic SIJ Injection Following a Composite of 3 Diagnostic Tests and a Pain Referral Diagram
The purpose of this study is to determine the predictive value of a composite of 3 simple clinically practical diagnostic tests (Mekhail's test, Patrick's and Thigh thrust) combined with a pain referral diagram in predicting…
- Trial name
- NCT01875406
- Testing
- diagnostic exercises
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The Cleveland Clinic
Autogenous Bone Grafts
Effect of Local Administration of Morphine for Analgesia After Iliac Bone Graft Harvest
The goal of the current study was to evaluate the analgesic efficacy of low-dose morphine administered to the site of bone graft harvesting in patients undergoing orthopedic surgery.
- Trial name
- NCT01037335
- Testing
- morphine
- Sponsor
- The Cleveland Clinic
Critical Limb Ischemia
Correlation Between FlowMet™ and Other Gold Standard Assessments in the Management of Critical Limb Ischemia (CLI)
The purpose of this study is to demonstrate the utility of the FlowMet™ device in the assessment of perfusion in subjects suspected of or being treated for critical limb ischemia, in comparison to other gold standard…
- Trial name
- NCT03094559
- Testing
- FlowMet
- Where
- United States
- Sponsor
- The Cleveland Clinic
Nonalcoholic Fatty Liver
Vitamin D Replacement in Nonalcoholic Fatty Liver Disease
Vitamin D deficiency is very common in patients with fatty liver disease as evidenced by our observations in the Metabolic Liver Clinic and that reported by others.
- Trial name
- NCT03084328
- Testing
- Vitamind D
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- The Cleveland Clinic
Acute on Chronic Heart Failure
Model for Heart Failure ExAcerbation Reduction Trial
Heart failure is the leading cause of hospitalizations and readmissions in the United States and is a tremendous economic strain on our healthcare system.
- Trial name
- HEART (NCT01726985)
- Testing
- Parameter Based Clinical Disposition
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Cleveland Clinic Florida
Arthritis
A Prospective Study to Evaluate the Effectiveness of a Haemostatic Agent in Primary Unilateral Total Hip Arthroplasty
This is a prospective, randomized, controlled, single-center study to assess the effectiveness of Vitagel, a surgical hemostat, in primary unilateral total hip arthroplasty (THA).
- Trial name
- NCT01285024
- Testing
- Vitagel
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- The Cleveland Clinic
Duration of Hospitalization
Volatile Anesthetic Choice and Duration of Hospitalization: A Quality Improvement and Cost-control Project
Preliminary retrospective data suggest that the relatively soluble but inexpensive volatile anesthesia isoflurane prolongs the duration of hospitalization compared to the less soluble but more expensive anesthetic sevoflurane.
- Trial name
- NCT01379664
- Testing
- Isoflurane, Sevoflurane
- Where
- United States
- Volunteers
- 1,584 people
- Sponsor
- The Cleveland Clinic
Surgical Wound Infection
Supplemental Postoperative Oxygen and Wound Infection in Morbidly Obese Patients
The investigators propose to test the hypothesis that the incidence of major complications related to infection or inadequate healing is reduced in morbidly obese patients given 80% inspired oxygen during, and for 12-18 hours…
- Trial name
- NCT00315822
- Testing
- 80% oxygen, 30% oxygen
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- The Cleveland Clinic
Chronic Kidney Disease Stage 3 and 4
Vitamin D Supplement Study for Stage Three and Four Chronic Kidney Disease (CKD) Patients
The purpose of this study is to examine the effectiveness of vitamin D3 versus vitamin D2 in raising vitamin D levels and suppressing parathyroid hormone levels in patients with kidney disease who are not on dialysis.
- Trial name
- UPGRADE (NCT01173848)
- Testing
- Ergocalciferol, Cholecalciferol
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- The Cleveland Clinic
Gall Stones
Electrohydraulic Versus Laser Lithotripsy for Treatment of Difficult to Remove Biliary Stones
Bile duct stones that can't be removed by conventional means can often be removed after fragmentation by shock waves (lithotripsy).
- Trial name
- EHLvlaser (NCT01571271)
- Testing
- Laser Lithotripsy, Electrohydraulic Lithotripsy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- The Cleveland Clinic
Benign Neoplasm of Intestinal Tract, Primary Malignant Neoplasm of Intestinal Tract
Impact of Perioperative Intravenous Fluid Utilization on Postoperative Outcomes
Subjects undergoing surgery on the small or large bowel will be randomized to one of 2 groups, a normal fluid amount group and a reduced fluid amount group to evaluate the impact of this change on recovery after surgery.
- Conditions
- Benign Neoplasm of Intestinal Tract, Primary Malignant Neoplasm of Intestinal Tract, Secondary Malignant Neoplasm of Intestinal Tract
- Trial name
- NCT01563991
- Testing
- Normal fluid volume, Reduced fluid volume
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- The Cleveland Clinic
Pancreatic Duct Strictures, Biliary Duct Strictures
Bile and Bile Duct/Pancreatic Duct Brushings Database for Patients With Pancreato-biliary Stricture
The purpose of this study is to create a long-term storage of bile and brushings of pancreato-biliary duct in patients diagnosed with pancreato-biliary stricture for future research.
- Trial name
- NCT01565460
- Testing
- Sample Collection
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The Cleveland Clinic
Biliary Stricture
Factors Predicting Positive Yields on Biliary Brush Cytology During Endoscopic Retrograde Cholangiopancreatography
To determine factors associated with a positive yield of malignancy on biliary brush cytology obtained by ERCP.
- Trial name
- ERCP (NCT00894348)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The Cleveland Clinic
Arthritis
Real Time 3D Imaging and Surrogate Bone Model
This is an observer-blinded prospective randomized clinical trial to define the efficacy of a new technology developed at the Cleveland Clinic to improve the positioning of the acetabular shell in total hip arthroplasty.The…
- Trial name
- NCT02204007
- Testing
- 3D imaging & surrogate bone model
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
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