Clinical trials: sponsored by Al-Azhar University
Computer Assisted, Navigation
Computer Assisted Navigation on Endoscopic Sinus Surgery for Treatment of Sinonasal Polyposis
This study aimed to compare Endoscopic Sinus Surgery with and without image guidance, analyzing a number of parameters that can impact efficacy in cases of nasal polyposis.
- Conditions
- Computer Assisted, Navigation, Endoscopic Sinus Surgery, Sinonasal Polyposis
- Trial name
- NCT07575022
- Testing
- Endoscopic sinus surgery with Computer Assisted Navigation, Endoscopic sinus surgery
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Deep Bite Malocclusion, Intrusion of Tooth
Maxillary Incisor Intrusion Using Utility Arch Assisted With Micro-osteoperforations
Study will be directed to evaluate the dentoalveolar changes following maxillary incisor intrusion using utility arch assisted with micro-osteoperforations in deep bite cases.
- Conditions
- Deep Bite Malocclusion, Intrusion of Tooth, Orthodontic Tooth Movement, Root Resorption
- Trial name
- MOPs (NCT07566676)
- Testing
- Micro-osteoperforations, Utility arch
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Al-Azhar University
Sensori-Neural Deafness, Exosomes
A Randomized Trial of Intratympanic Drug Delivery: Evaluating the Efficacy and Safety of Dexamethasone-Loaded Exosomes Versus Standard Therapy in Acute Sensorineural Hearing Loss.
Primary Objective To compare the efficacy of a single course of IT Exo-Dex versus conventional IT dexamethasone and exosome vehicle alone, as measured by the mean change in pure-tone average (PTA; 0.5, 1, 2, 4 kHz) from baseline…
- Trial name
- EXO-DEX-SNHL (NCT07568184)
- Testing
- exosomes derived from human umbilical cord mesenchymal stem cells
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kafrelsheikh University
Chronic Obstructive Pulmonary Disease (COPD)
High Velocity Nasal Insufflation Versus Non Invasive Ventilation in COPD Patients With Acute Hypercapnic Respiratory Failure
This study is a randomized clinical trial that compares two methods of non-invasive respiratory support in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) complicated by acute hypercapnic…
- Trial name
- HVNI vs NIV CO (NCT07561177)
- Testing
- High-Velocity Nasal Insufflation (HVNI), Non-Invasive Ventilation (NIV)
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Al-Azhar University
Oral Microbial Load
Antibacterial Effect of Moringa Mouthwash in Children With Mixed Dentition Wearing Orthodontic Appliances
This randomized controlled study aims to evaluate the microbiological effectiveness of Moringa mouthwash in children with mixed dentition wearing removable orthodontic appliances.
- Trial name
- MOR-MW (NCT07536438)
- Testing
- Moringa mouthwash, Oral Hygiene Routine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Orthodontic Patients
Efficacy of Skeletally Anchored Modified Leaf Expander in Maxillary Molar Distalization
Background: Distalization in orthodontics is one of conservative treatment modalities that result in gaining space especially in dental orthodontic cases of class ΙΙ molar relationship.
- Trial name
- NCT07534072
- Testing
- skeletally anchored Modified Leaf Expander
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Class I Malocclusion, Maxillary Prognathism
Nano Coated Orthodontic Miniscrews for en Mass Retraction of the Upper Arch
study will be directed to evaluate silver-hydroxyapatite nano-coated versus uncoated orthodontic miniscrews for en masse retraction of the upper anterior segment.
- Conditions
- Class I Malocclusion, Maxillary Prognathism, Orthodontic Tooth Movement
- Trial name
- NCT07521267
- Testing
- Silver nanoparticles, uncoated titanium miniscrews
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Al-Azhar University
Amputation, Prosthesis User
Satisfaction and Quality of Life Among Prosthetic Users in Gaza Governorate ,
Prosthetic devices help amputees regain mobility and improve appearance. When patients are satisfied with their prosthesis, they are more likely to use it consistently, leading to better rehabilitation outcomes.
- Conditions
- Amputation, Prosthesis User, Satisfaction, Quality of Lifte
- Trial name
- PROINGA (NCT07519746)
- Testing
- Observational Study - No Intervention
- Where
- Palestinian Territories
- Volunteers
- 128 people
- Sponsor
- Yeditepe University
Gingival Hyperpigmentation, Gingival Melanin Pigmentation
Vitamin C for Gingival Depigmentation
The purpose of this study is to evaluate the clinical and histopathological efficacy of topical vitamin C applications using three modalities (topical gel, microneedling , and mesotherapy) in gingival depigmentation.
- Trial name
- VitC-DePg (NCT07513727)
- Testing
- Topical Vitamin C ( control Arm), Vitamin C mesotherapy, Microneedling technique
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Edentulous Alveolar Ridge In Mandible, Complete Edentulism
"Retention and Quality of Life in Mandibular Overdentures Using Two Attachment Systems: A Randomized Clinical Trial"
This randomized clinical trial investigates the effect of two different attachment systems-Equator and Novaloc-on the retention, patient satisfaction, and oral health-related quality of life of mandibular implant overdentures.
- Conditions
- Edentulous Alveolar Ridge In Mandible, Complete Edentulism, Dental Implant, Implant Retained Overdenture
- Trial name
- NCT07513155
- Testing
- OT-Equator Attachment, Novaloc Attachment
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Hot Climate, Bleeding Tendency
Hot Climate on Bleeding Tendency After Cardiac Surgery in Egyptian Patients
This work aimed to assess the effect of regional climatic differences on postoperative bleeding in Egyptian patients undergoing cardiac surgery with cardiopulmonary bypass, by comparing outcomes between patients from hot climate…
- Conditions
- Hot Climate, Bleeding Tendency, Cardiac Surgery, Egyptian Patients
- Trial name
- NCT07510022
- Testing
- Open heart surgery
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Al-Azhar University
Edentulous Alveolar Ridge In Mandible, Complete Edentulism
Using Two Different Attachments (Equator Vs Ball and Sockets) Retaining Mandibular Implant Overdenture in Order to See Bone Changes and Occlusal Force Distribution
Alveolar ridge resorption is an unavoidable consequence in complete denture wearers due to limited retention and stability. Implant-retained overdentures enhance retention, stability, and masticatory performance while reducing…
- Conditions
- Edentulous Alveolar Ridge In Mandible, Complete Edentulism, Dental Implant, Attachments
- Trial name
- NCT07241481
- Testing
- Ball & Socket Attachment, Equator Attachment
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Dental Caries, Primary Molars
Clinical Performance of Four Restorative Materials in Primary Molars
This randomized clinical trial aims to compare the clinical and radiographic performance of four direct restorative materials used for restoring carious primary molars in children.
- Trial name
- NCT07504393
- Testing
- Cention N, Stela, SDI, Australia, Beautifil II, Shofu, Japan
- Volunteers
- 92 people
- Sponsor
- Al-Azhar University
Posterior Crossbite, Maxillary Expansion
Quad Helix vs RME for Posterior Cross-bite in Egyptian Children
This randomized clinical trial aims to evaluate and compare the effectiveness of the Quad Helix (QH) appliance versus Rapid Maxillary Expanders (RME) in treating posterior cross-bite in Egyptian children during the mixed…
- Conditions
- Posterior Crossbite, Maxillary Expansion, Transverse Maxillary Deficiency
- Trial name
- Expansion (NCT07500194)
- Testing
- Quad Helix(QH) Appliance, Rapid Maxillary Expanders
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Clinical Outcomes, Radiographic Outcomes
Clinical and Radiographic Outcomes of Lesion Sterilization and Tissue Repair Using Zinc Oxide/ 6-gingerol Mix Versus Triple Antibiotic Paste in Non-vital Primary Molars
This study aims to evaluate and compare the clinical and radiographic outcomes of Lesion sterilization and tissue repair using zinc oxide/ 6-gingerol mix versus triple antibiotic paste in non-vital primary molars.
- Conditions
- Clinical Outcomes, Radiographic Outcomes, Lesion Sterilization, Tissue Repair
- Trial name
- NCT07488416
- Testing
- Zinc oxide/ 6-gingerol mix, Triple antibiotic paste
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Mandibular Expansion
Self-activated Leaf Expander Versus William's Expander in Expansion of Collapsed Mandibular Arch
Self-activated leaf expander versus William's expander in expansion of collapsed mandibular arch
- Trial name
- NCT07480148
- Testing
- self activated leaf expander, williams's expander
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Post Operative Pain
Evaluating Postoperative Pain and Antibacterial Effect of Ultrasonic and 980 nm Diode Laser Combination
This study is a parallel randomized controlled clinical trial that was designed and interpreted according to Preferred Reporting Items for Randomized Trial in Endodontics (PRIRATE) 2020 guidelines.
- Trial name
- Postoperative (NCT07041736)
- Testing
- diode laser, conventional irrigation, Ultrasonic
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Metformin Gel, Bone Graft
Adding 1% Metformin Gel to Bone Graft in Association With Immediate Dental Implants
This study aimed to investigate whether combining xenografts with Metformin Gel gel enhances bone regeneration and improves implant outcomes.
- Conditions
- Metformin Gel, Bone Graft, Immediate Dental Implants
- Trial name
- NCT07469254
- Testing
- Metformin gel-xenograft, Xenograft
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Al-Azhar University
Edentulous Mandible
Radiographic and Clinical Evaluations of Mandibular Implant-Supported Overdentures Supported by Conventional and Zirconia CAD/CAM Bars: A Randomized Clinical Trial
This randomized clinical trial aimed to evaluate the radiographic and clinical evaluations of mandibular implant-supported overdentures supported d by two different bar materials。 Completely edentulous patients received two…
- Trial name
- NCT07429149
- Testing
- Cobalt-Chromium Bar Attachment, Zirconia CAD/CAM Bar Attachment
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sara Mohamed Fakhry Meligy Mohamed
Calcaneus Fractures
Comparative Study Between Internal Fixtion And Primary Subtalar Arthrodesis In Comminuted Intra-Articular Calcaneal Fracture
This study is to compare clinical outcome of Sanders type III or IV intra-articular calcaneal fracture treated with open reduction and internal fixation (ORIF) versus ORIF and primary subtalar arthrodesis (PSTA).
- Trial name
- NCT07423507
- Testing
- Primary Subtalar Arthrodesis, Open reduction and internal fixation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ahmed Gamal Ibrahim Saleh