Clinical trials: sponsored by University of Alabama at Birmingham
Prostate Cancer, Prostate Adenocarcinoma
Pilot Trial Evaluating Stereotactic Body Radiotherapy With Integrated Boost for Clinically Localized Prostate Cancer (RAD 1203)
This study will investigate the safety, tolerability, and effectiveness of giving a higher dose to the part of the prostate which contains the cancer while giving a standard radiation dose to the entire prostate.
- Conditions
- Prostate Cancer, Prostate Adenocarcinoma, Radiation Toxicity, Sexual Dysfunction
- Trial name
- NCT01856855
- Testing
- Stereotactic Body Radiation Therapy with Integrated Boost
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- John Fiveash, MD
Hepatocellular Carcinoma
[68Ga]DOTATATE-PET/MRI in Hepatocellular Carcinoma
There is great need for new therapeutic options for patients with hepatocellular carcinoma (HCC). This proposal will assess the feasibility of a novel theranostic approach to HCC using [68Ga]DOTATATE, a recently approved positron…
- Trial name
- NCT03648073
- Testing
- [68Ga]DOTATATE-PET/MRI
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Alabama at Birmingham
Survey, Family Life
Social Media Use in Sickle Cell Patients
Surveys of patients to identify primary social media sources for health news.
- Trial name
- NCT05182216
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Shared Decision Making
Enhancing Shared Decision-Making in Breast Cancer
The objective of this trial is to conduct a two-arm, randomized controlled trial (RCT) of SDM Treatment Plans (TPs) delivered at the time of decision-making compared to standard oncology care (delayed delivery of standard-of-care…
- Trial name
- NCT03806738
- Testing
- Intervention-specific Carevive questionnaire, Standard of Care questionnaire
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Alabama at Birmingham
Metabolic Syndrome, Insulin Sensitivity
Effect of Phosphorus Additives on the Metabolome in Healthy Adults
This study evaluates the effect of phosphorus supplementation on the human metabolome. The investigators will do so by conducting a cross-over study in healthy adults consuming a study diet (normal diet supplemented by neutral…
- Conditions
- Metabolic Syndrome, Insulin Sensitivity, Cardiovascular Diseases
- Trial name
- NCT03841786
- Testing
- Phosphorus-supplemented study diet, Control Diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Metabolic Syndrome, Obesity
Effect of Low Carbohydrate Versus Low Fat Diet in the Treatment of Dyslipidemia in Obese Children With Metabolic Syndrome
Two-arm, parallel design with children between the ages of 10 - 18 with obesity and metabolic syndrome randomized (15 per group) to reduced-carbohydrate diet or a reduced-fat diet for 8 weeks.
- Conditions
- Metabolic Syndrome, Obesity, Dyslipidemias
- Trial name
- NCT03937960
- Testing
- Carbohydrate restricted group, Standard low fat diet
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Chronic Kidney Disease, Albuminuria
Vascular Effects of Mineralocorticoid Receptor Antagonism in Kidney Disease
Vascular endothelial dysfunction increases cardiovascular (CV) risk and contributes to the progression of chronic kidney disease (CKD).
- Trial name
- VEMAKD (NCT02497300)
- Testing
- Spironolactone, Amiloride
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Alabama at Birmingham
Diabetes, Obesity
Implementation of a Cardiometabolic Disease Staging System in Primary Care
The aim of this study is to develop a clinical decision support system (CDSS) that incorporates obesity management guidelines and treatment options for use by physicians and, potentially, patients based on a cardiometabolic…
- Conditions
- Diabetes, Obesity, Overweight
- Trial name
- NCT04922294
- Testing
- Clinical decision support system
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Contact Lens Complication, Dry Eye
Total30 Sphere Contact Lenses
The purpose of this study is to map comfort over the full wear day in established, asymptomatic, soft CL wearers who are refit in Total30 Sphere CLs.
- Trial name
- NCT05183022
- Testing
- Total30 Sphere Contact Lenses
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Premature; Infant, Light-for-dates
Early Progressive Feeding in Human-Milk Fed Extremely Preterm Infants: A Randomized Trial
To test the hypothesis that progressive feeding without minimal enteral feeding (MEF) compared to progressive feeding preceded by a 4-day course of MEF will result in an increased number of days alive on full enteral feeding in…
- Trial name
- NCT02915549
- Testing
- Progressive Feeding without MEF, Progressive Feeding with MEF
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Cancer, Overweight and Obesity
Daughters, dUdes, Mothers and othErs Fighting Cancer Together
The purpose of this protocol is to conduct a 2-arm, single-blinded randomized controlled clinical trial (RCT) in which 56 dyads (defined as consisting of an overweight or obese cancer survivor of an obesity-related cancer and an…
- Trial name
- DUET (NCT04132219)
- Testing
- eHealth Intervention
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of Alabama at Birmingham
Cancer Survivor
Harvest for Health in Older Cancer Survivors
Gardening interventions yield a multitude of measurable benefits that are evaluable within the context of a clinical trial. Harvest for Health forges new inroads in the delivery of holistic interventions to high risk populations…
- Trial name
- NCT02985411
- Testing
- Immediate Gardening Intervention, Delayed Gardening Intervention
- Where
- United States
- Volunteers
- 381 people
- Sponsor
- University of Alabama at Birmingham
Chronic Disease
Reducing Chronic Disease Health Disparities in the Deep South
The study is a gardening intervention among 150 older cancer survivors and individuals living with chronic disease (cardiovascular disease and diabetes) in the states of Alabama and Mississippi.
- Trial name
- NCT04297826
- Testing
- Harvest for Health
- Where
- 2 sites in United States
- Volunteers
- 137 people
- Sponsor
- University of Alabama at Birmingham
Acute Kidney Injury
Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates
Introduction: Based on single-center data, approximately 1 of every 3 newborns admitted to tertiary level neonatal intensive care units (NICU) develops acute kidney injury (AKI), and those with AKI have significantly worse…
- Trial name
- AWAKEN (NCT02443389)
- Where
- United States
- Volunteers
- 2,186 people
- Sponsor
- University of Alabama at Birmingham
Family Caregivers, Cancer
Pilot Optimization Trial of Decision Partnering Intervention for Advanced Cancer Family Caregivers
Using a highly innovative methodology, the Multiphase Optimization Strategy (MOST), the purpose of this study is to pilot test, for the first time, an optimization trial approach to develop and refine the decision partnering…
- Trial name
- CASCADE (NCT03947606)
- Testing
- CASCADE (CAre Supporters Coached to be Adept DEcision partners)
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Neurodevelopmental Abnormality
Two Year Developmental Follow-up for PREMOD2 Trial (Premature Infants Receiving Milking or Delayed Cord Clamping)
An extension of the PREMOD2 trial, the PREMOD2 Follow-Up trial will evaluate the neurodevelopmental outcomes at 22-26 months corrected age of preterm children who received UCM or DCC.
- Trial name
- PREMOD2FU (NCT03476980)
- Testing
- Randomized to Umbilical Cord Milking at birth, Randomized to Delayed Cord Clamping at birth
- Where
- 18 sites in United States, Canada and 2 more
- Volunteers
- 1,200 people
- Sponsor
- Sharp HealthCare
Intraventricular Haemorrhage Neonatal, Death; Neonatal
Premature Infants Receiving Milking or Delayed Cord Clamping: PREMOD2
This study is being done to find out whether umbilical cord milking (UCM) is at least as good as or better than delayed cord clamping (DCC) to reduce bleeding in the brain or prevent death in premature newborns.
- Trial name
- PREMOD2 (NCT03019367)
- Testing
- Umbilical cord milking UCM, Delayed cord clamping DCC
- Where
- 18 sites in United States, Canada and 2 more
- Volunteers
- 1,201 people
- Sponsor
- Sharp HealthCare
Multiple Sclerosis
Activity and Balanced Eating to Reduce Comorbidities and Symptoms of MS
Multiple sclerosis (MS) is the leading cause of irreversible neurological disability among young women and the second leading cause of disability among young men in the U.S.
- Trial name
- ABC's of MS (NCT03808545)
- Testing
- Behavioral Intervention for Physical Activity in Multiple Sclerosis (BIPAMS), BIPAMS + Diet
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Alabama at Birmingham
Cervical Cancer
Self-Sampling for Human Papillomavirus (HPV) Testing in African American Women - Mississippi Delta
The purpose of this study is to examine the efficacy and costs of this patient-centered approach ("Choice" between two cervical cancer screening modalities) in adherence to cervical cancer screening as compared to the current…
- Trial name
- HPV (NCT03713710)
- Testing
- Pap testing, Choice
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Menopause Surgical, Estrogen Deficiency
Understanding the Roles of Hormones in Adipocyte Remodeling Following Menopause
The overarching aims of this study are to: 1. Characterize the rate of in vivo adipogenesis, and changes in adipose tissue gene and protein expression, in the scABD and scFEM depots of women undergoing surgical menopause (↓E2…
- Conditions
- Menopause Surgical, Estrogen Deficiency, Adiposity, Follicle-Stimulating Hormone Deficiency
- Trial name
- RESUME-2 (NCT03856268)
- Testing
- 'Surgical Menopause' Group, 'Drug-Induced Menopause' Group
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.