Clinical trials: sponsored by Kafrelsheikh University
Endoscopic Pituitary Transnasal Approach, Minimally Invasive Eyebrow Incision
Endoscopic Pituitary Lesions Transnasal Approach and Minimally Invasive Eyebrow Incision Approach
This study aims to compare the effect of endoscopic transnasal approach versus minimally invasive eyebrow incision approach for pituitary lesions in terms of safety, efficacy and postoperative recovery.
- Trial name
- NCT07907380
- Testing
- Endoscopic Transnasal Approach, Minimally Invasive Eyebrow Approach
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Stress
Stress Modulation and Dynamic Balance
This three-arm, parallel-group, randomized controlled trial (RCT) investigates whether dual-task therapeutic exercises (dynamic balance + cognitive task) improve perceived stress and dynamic balance in 72 healthy university…
- Trial name
- NCT07571369
- Testing
- Dynamic balance exercises, Control group, Dual task exercises
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Stress Urinary Incontinence (SUI)
Comparison of Two Autologous Sling Procedures for Stress Urinary Incontinence in Women
This study compares two operations for stress urinary incontinence in adult women. Stress urinary incontinence means leaking urine during activities such as coughing, sneezing, laughing, or exercising.
- Trial name
- NCT07899450
- Testing
- Transobturator Autologous Vaginal Wall Sling, Autologous Rectus Sheath Pubovaginal Slinge
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mohamed Ehab Saad Fadl
Analgesic Efficacy, Dexmedetomidine
Analgesic Efficacy of Adding Dexmedetomidine to Erector Spinae Plane Block Versus Subcostal Transverse Abdominis Plane Block in Laparoscopic Cholecystectomy
Our scientific work aimed to evaluate the analgesic efficacy of dexmedetomidine as an adjuvant to erector spinae plane block versus subcostal transverse abdominis plane block in patients undergoing laparoscopic cholecystectomy.
- Conditions
- Analgesic Efficacy, Dexmedetomidine, Erector Spinae Plane Block, Subcostal Transverse Abdominis Plane Block
- Trial name
- NCT07075913
- Testing
- Subcostal transverse abdominis plane block, Erector spinae plane block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Kafrelsheikh University
Urolithiasis, Stone, Kidney
Efficacy of Different Modalities on Management of Renal Hard Stones
The study has been conducted in Urology department at Kafrelsheikh University Hospital between Feburary 2021 to December 2023. informed consent was taken from eligible patients and were randomized into three groups, Group A…
- Trial name
- NCT07445646
- Testing
- Lithotripsy using Flexible ureteroscope, Extracorporeal shock wave lithotripsy (ESWL), holmium laser lithotripsy using Karl® Storz MIP
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Kafrelsheikh University
Supraspinatus Tendinitis
HILT vs ESWT in Supraspinatus Tendinitis
This randomized controlled trial aims to compare the effectiveness of High-Intensity Laser Therapy (HILT) and Extracorporeal Shock Wave Therapy (ESWT) in patients with supraspinatus tendinitis.
- Trial name
- NCT07615920
- Testing
- High-Intensity Laser Therapy, Extracorporeal Shock Wave Therapy, Conventional Physical Therapy
- Where
- Saudi Arabia
- Volunteers
- 90 people
- Sponsor
- Kafrelsheikh University
Hirschprung's Disease, Constipation
Comparative Research Between Swenson and Soave Operations for Pediatric Patients Who Have Hirschsprung Disease
Hirschsprung's disease is characterized by a lack of enteric nervous system ganglion cells (aganglionosis) in a variable extent of distal bowel.
- Conditions
- Hirschprung's Disease, Constipation, RECTUM
- Trial name
- NCT07410286
- Testing
- Swenson operation includes resection of the aganglionic segment and anastomosis with full thickness layer above the dentate., Soave procedure: includes resection of the aganglionic segment and anastomosis with submucosal thickness layer above the dentate.
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ahmed Aouf
Renal Stone, Pediatric
Flexible Ureteroscopy Versus Mini- Percutaneous Nephrolithotomy in Management of Pediatric Renal Stones Less Than 2 cm
This single-center, prospective, two-arm randomized controlled trial included 58 patients younger than 18 years who were allocated 1:1 to Mini-PCNL or FURS between June 2023 and December 2024.
- Trial name
- NCT07870200
- Testing
- Group A :Flexible ureteroscope group, Group B : Mini perc group
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Elsayed Abdelhalim Elsayed
Metabolic Dysfunction-Associated Steatoic Liver Disease
Vitamin E Versus Silymarin in Non Diabetic MASLD Patients
MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease), is a chronic liver condition marked by excessive fat buildup (steatosis) in liver cells, linked to at least one metabolic risk factor like obesity, type 2…
- Trial name
- MASLD (NCT07863648)
- Testing
- Vitamin E 800 IU/d, Silymarin 420 mg
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Kafrelsheikh University
Spastic Diplegia Cerebral Palsy
Dual-Task Training in Children With Spastic Diplegic Cerebral Palsy
This randomized controlled trial aims to investigate the effect of dual-task oriented training on functional performance in children with spastic diplegic cerebral palsy. Participants will be randomly assigned to two groups.
- Trial name
- NCT07870135
- Testing
- Dual-Task oriented, Traditional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Raneem Ahmad Mohammad Ashshi
Pleural Effusion, Exudative Pleural Effusion
Forceps Versus Cryobiopsy in Undiagnosed Exudative Pleural Effusion Using Rigid Thoracoscopy
This study compared two ways of taking tissue samples from the lining of the lung (pleura) during rigid thoracoscopy in adults with pleural effusion of unknown cause: conventional forceps biopsy and cryobiopsy (freezing the…
- Conditions
- Pleural Effusion, Exudative Pleural Effusion, Mesothelioma
- Trial name
- NCT07869056
- Testing
- Pleural Cryobiopsy, Pleural Forceps Biopsy
- Where
- 2 sites in Egypt
- Volunteers
- 40 people
- Sponsor
- Ahmed Zakaria Elsaeed
HELICOBACTER PYLORI INFECTIONS
Lignin in Treatment of Helicobacter Pylori Infection
The goal of this clinical trial is to learn if drug hydrolyzed lignin works to treat H pylori infection in adults. It will also learn about the safety of drug lignin n the sitting of H pylori infection, and if it halts the side…
- Trial name
- NCT07246681
- Testing
- Hydrolyzed Lignin
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Zagazig University
Major Depression
iTBS Versus Standard 10 Hz rTMS for Treatment-Resistant Depression (TRD)
This randomised, parallel-group, non-inferiority trial compared intermittent theta burst stimulation (iTBS, 3-minute sessions) with standard 10 Hz repetitive transcranial magnetic stimulation (rTMS, 37-minute sessions) applied to…
- Trial name
- iTBS-TRD (NCT07852065)
- Testing
- iTBS, rTMS
- Where
- Egypt
- Volunteers
- 182 people
- Sponsor
- Kafrelsheikh University
Sleep Disturbances
The Effect of Non Invasive Stellate Ganglion Disrupting on Sleep Disturbances on Postmenopausal Female
The goal of this clinical trial is to asses the effect of non invasive stellate ganglion disrupting on sleep distyrbances on postmenopausal female .
- Trial name
- NCT07224295
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), Lactium
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Kafrelsheikh University
Polycystic Ovary Syndrome, Infertility
Inositol in Letrozol Resistant PCOS Women
Polycystic ovary syndrome (PCOS),is a complex neuro-endocrine disorder affecting approximately 5% to 10% of women in reproductive age.Inositols are considered insulin sensitizers, as they modulate the members of insulin signaling…
- Trial name
- NCT07585396
- Testing
- Myoinositol, Metformin
- Where
- Egypt
- Volunteers
- 136 people
- Sponsor
- Kafrelsheikh University
Stage II Grade B Periodontitis
Active Oxygen Gel vs Chlorhexidine Gel in Stage II Grade B Periodontitis
This randomized controlled clinical trial will evaluate the effectiveness of locally delivered active oxygen gel and chlorhexidine gel as adjuncts to scaling and root planing in the treatment of stage II grade B…
- Trial name
- NCT07840716
- Testing
- Active oxygen gel, Chlorhexidine gel
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Assess the Quality of Life of Pregnant Women With Fibromyalgia
Effect of Community-Based Nursing Interventions on Quality of Life in Pregnant Women With Fibromyalgia
Fibromyalgia is a long-term, complex disorder marked by widespread pain in the muscles and joints, ongoing fatigue, sleep disturbances, mood changes, and cognitive difficulties, all of which can significantly disrupt daily…
- Trial name
- NCT07821892
- Testing
- community based nursing interventions, routine care
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- farha Ali El-refaie Abdelhamed
Complete Edentulism
Microbial Adhesion and Peri-Implant Tissue Health in All-on-Four Hybrid Prostheses Supported by Zantex or Zirconia Frameworks
This study compares two materials (Zantex and Zirconia) used to make fixed full-arch dental prostheses supported by four dental implants (the "All-on-Four" technique) in patients who have no natural teeth in the lower jaw.
- Trial name
- NCT07811661
- Testing
- Zirconia Framework, Zantex Framework
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Kafrelsheikh University
Physiological Gingival Pigmentation
Laser Treatment With Methylene Blue vs. Nanoparticle-Assisted Photodynamic Therapy for Gingival Pigmentation: A Randomized Clinical Trial
This prospective, randomized, controlled, single-blinded, three-arm clinical trial compared the clinical effectiveness of conventional methylene blue-mediated photodynamic therapy (MB-PDT) and methylene blue nanoparticle-mediated…
- Trial name
- MB-Laser-GP (NCT06834087)
- Testing
- Laser-Assisted Gingival Depigmentation, Drug: Conventional Methylene Blue-Mediated Photodynamic Therapy, Drug: Methylene Blue Nanoparticle-Mediated Photodynamic Therapy
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Roaa Hadi Hussein Jasem
Impacted Mandibular Third Molar
The Effect of Topical Application of Hyaluronic Acid and Melatonin Mixture Following Surgical Extraction of Impacted Mandibular Third Molars .
This randomized controlled clinical trial aims to evaluate the clinical and radiographical effects of the application of a mixture of hyaluronic acid and melatonin after surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07735806
- Testing
- Hyaluronic acid and Melatonin mixture, Gel foam
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kafrelsheikh University