Research institution
Loma Linda University Clinical Trials
Studies where Loma Linda University is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 48Dental Caries, Dental Plaque
Effect of Xylitol- Versus Erythritol-Sweetened Mints on Plaque ATP-Bioluminescence Readings
This study will assess the effectiveness of erythritol and xylitol in suppressing biofilm activity, using both within-subject and between-group comparisons.
- Trial name
- NCT07902323
- Testing
- Xylitol, Erythritol
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Gut Health, LBP
The Effects of Mango on Gut Health Markers
This is an ancillary study of NCT06159543, which was a clinical trial that examined the effect of a 12-week 1.5 cups daily mango crossover intervention on cardiometabolic outcomes in individuals with prediabetes, male and female…
- Conditions
- Gut Health, LBP, Short Chain Fatty Acids, sCD14
- Trial name
- NCT07559604
- Testing
- Mango
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Loma Linda University
Fruit and Vegetable Intake, University Students
Fruit & Vegetable Consumption and Behavioral Determinants Among Health Profession Students
This is an ancillary study of National Clinical Trial (NCT) #06229262 (which was a clinical trial that examined the effect of a 12-week mango intervention in college/university students).
- Conditions
- Fruit and Vegetable Intake, University Students, College Students, Self-Efficacy
- Trial name
- NCT07848958
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Healthy Subjects
Shoulder Strength in Baseball Players
The purpose of this graduate student research study is to transform the existing concepts surrounding shoulder strength in baseball players, particularly in the context of retroverted shoulders.
- Trial name
- NCT07209423
- Testing
- Strength and Range of Motion
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Acute Rejection of Renal Transplant, Graft Failure
Dd-cfDNA and Treg in Prediction of Kidney Transplant Acute Rejection
Acute rejection after kidney transplantation should ideally be diagnosed prior to immunologic injury in a non-invasive fashion in order to improve long-term graft function.
- Trial name
- NCT05084768
- Testing
- Donor-derived cell-free DNA
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Loma Linda University
Patellofemoral Pain
Limited Ankle Dorsiflexion and Effect on Single Limb Squats in Individuals With Patellofemoral Pain
The purpose of this graduate student research study is to investigate the relationship between limited ankle dorsiflexion and the potential effects on a single limb squat task in the Patellofemoral/Knee Pain population.
- Trial name
- NCT05285007
- Testing
- Mobilization with Movement, No mobilization with movement and education
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Domestic Violence
Occupational Therapy for Adults Who Have Experienced Intimate Partner Violence (IPV)
The purpose of this graduate student research study is to understand the effectiveness of an occupational therapy program in a domestic violence shelter. It is expected that participation will last about 6 weeks.
- Trial name
- IPV (NCT06808828)
- Testing
- Health and coping skills
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Loma Linda University
Peri-Implantitis
Regenerative Outcomes for Peri-implant Bony Defects Using Amnion-chorion Barrier vs. Collagen Membrane
The purpose of this study is to compare the clinical and radiographic outcomes of two different barrier membranes-amnion-chorion membranes (ACM) and conventional collagen membranes-used in guided bone regeneration (GBR)…
- Trial name
- NCT07032259
- Testing
- BioXclude Amnion Chorion Membrane, Collagen Membrane
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Cognition, Immunity
Immune and Cognitive Benefits of Mango Intake in Young Adults
The main objectives of our proposed study are to determine the effects of mango consumption on immune and cognitive functions in free-living college going young adults aged 18-30 years
- Trial name
- NCT06229262
- Testing
- Mango group
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Iron Deficiency Anemia
Daily Iron vs Every-other-day Iron for Pediatric Patients With IDA
Iron Deficiency Anemia (IDA) is a prevalent global health issue affecting a significant proportion of the population, including children.
- Trial name
- NCT06550362
- Testing
- iron sulfate
- Volunteers
- 100 people
- Sponsor
- Loma Linda University
Completed, with results posted
All 42Hypersensitivity Reactions
Conventional Prophylactic Oral Dexamethasone vs Short-course IV Dexamethasone in Paclitaxel Hypersensitivity
This study is a single center, prospective, randomized, open-label study aimed at determining the most effective means of preventing hypersensitivity reactions in gynecologic oncology patients receiving paclitaxel infusions.
- Trial name
- NCT03598426
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Loma Linda University
Hemorrhagic Shock, Acute Blood Loss Anemia
Low-Titer O Positive Whole Blood Versus Component Therapy for Emergent Transfusion in Trauma Patients
Adult male patients brought to the emergency department as Level A trauma activations who are receiving emergency blood transfusion. Objectives 1.
- Conditions
- Hemorrhagic Shock, Acute Blood Loss Anemia, Traumatic Brain Injury
- Trial name
- NCT05081063
- Testing
- Routine labs
- Where
- United States
- Volunteers
- 199 people
- Sponsor
- Loma Linda University
Gingival Inflammation
Efficacy of Eco-Friendly Toothpaste Tablets Versus Conventional Toothpaste Using PI and GI Index
Objectives: To assess the change in gingival index (GI) and plaque index (PI) when comparing the use of toothpaste tablets to conventional toothpaste.
- Trial name
- NCT05805865
- Testing
- Toothpaste Tablet, Conventional Toothpaste
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Bone Loss, Implant Complication
The Effects of Dis/Reconnection of Implant Abutments on Peri-implant Bone Levels
The aim of this study was to evaluate the effects of definitive abutment connection at the time of implant placement on peri-implant bone levels and soft tissue changes in posterior maxilla and mandible regions.
- Conditions
- Bone Loss, Implant Complication, Gingival Recession
- Trial name
- NCT04043286
- Testing
- Definitive abutment
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Anxiety, Dental, Dental Decay
A Comparison of Oral Sedation-related Events of Three Multiagent Oral Sedation Regimens in Pediatric Dental Patients
This study will compare the post sedation events from three different multi-drug oral sedation regimens in order to help pediatric dentists determine the best course of action for their patients and prepare parents appropriately…
- Trial name
- NCT05126459
- Testing
- Regimen 1, Regimen #2, Regimen #3
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Loma Linda University