Clinical trials: sponsored by Loma Linda University
Pancreatic Cancer, Adult
To Evaluate the Preliminary Efficacy of Our Digitally Enhanced CHW-led Intervention in Newly Diagnosed PDAC
The goal of this clinical trial is to learn if a community health worker led intervention that helps facilitate palliative care works to treat newly-diagnostic pancreatic cancer.
- Trial name
- NCT07591571
- Testing
- PAL-CHW-PDAC, Usual Care with Attention Control
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Loma Linda University
Dental Caries, Dental Plaque
Effect of Xylitol- Versus Erythritol-Sweetened Mints on Plaque ATP-Bioluminescence Readings
This study will assess the effectiveness of erythritol and xylitol in suppressing biofilm activity, using both within-subject and between-group comparisons.
- Trial name
- NCT07902323
- Testing
- Xylitol, Erythritol
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Gut Health, LBP
The Effects of Mango on Gut Health Markers
This is an ancillary study of NCT06159543, which was a clinical trial that examined the effect of a 12-week 1.5 cups daily mango crossover intervention on cardiometabolic outcomes in individuals with prediabetes, male and female…
- Conditions
- Gut Health, LBP, Short Chain Fatty Acids, sCD14
- Trial name
- NCT07559604
- Testing
- Mango
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Loma Linda University
Fruit and Vegetable Intake, University Students
Fruit & Vegetable Consumption and Behavioral Determinants Among Health Profession Students
This is an ancillary study of National Clinical Trial (NCT) #06229262 (which was a clinical trial that examined the effect of a 12-week mango intervention in college/university students).
- Conditions
- Fruit and Vegetable Intake, University Students, College Students, Self-Efficacy
- Trial name
- NCT07848958
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Healthy Subjects
Shoulder Strength in Baseball Players
The purpose of this graduate student research study is to transform the existing concepts surrounding shoulder strength in baseball players, particularly in the context of retroverted shoulders.
- Trial name
- NCT07209423
- Testing
- Strength and Range of Motion
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Acute Rejection of Renal Transplant, Graft Failure
Dd-cfDNA and Treg in Prediction of Kidney Transplant Acute Rejection
Acute rejection after kidney transplantation should ideally be diagnosed prior to immunologic injury in a non-invasive fashion in order to improve long-term graft function.
- Trial name
- NCT05084768
- Testing
- Donor-derived cell-free DNA
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Loma Linda University
Patellofemoral Pain
Limited Ankle Dorsiflexion and Effect on Single Limb Squats in Individuals With Patellofemoral Pain
The purpose of this graduate student research study is to investigate the relationship between limited ankle dorsiflexion and the potential effects on a single limb squat task in the Patellofemoral/Knee Pain population.
- Trial name
- NCT05285007
- Testing
- Mobilization with Movement, No mobilization with movement and education
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Anesthesia
Continuous Glucose Monitoring: A Pilot Study
The purpose of this study is to evaluate connectivity of the FDA approved DexCom G7® continuous glucose monitor in the operating room.
- Trial name
- NCT06614127
- Testing
- Dexcom G7® sensor placed in upper arm and positioned over deltoid, Dexcom G7® sensor placed in lateral thigh
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Loma Linda University
Domestic Violence
Occupational Therapy for Adults Who Have Experienced Intimate Partner Violence (IPV)
The purpose of this graduate student research study is to understand the effectiveness of an occupational therapy program in a domestic violence shelter. It is expected that participation will last about 6 weeks.
- Trial name
- IPV (NCT06808828)
- Testing
- Health and coping skills
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Loma Linda University
Postmenopausal
Short-term Circuit Training on Muscle Mass and Quality of Life in Sedentary Postmenopausal Women
The purpose of this graduate student research study is to provide healthcare professionals with evidence of the potential of circuit strength training in improving the physical and psychosocial well-being of postmenopausal women.
- Trial name
- NCT06445842
- Testing
- Exercise, No exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Peri-Implantitis
Regenerative Outcomes for Peri-implant Bony Defects Using Amnion-chorion Barrier vs. Collagen Membrane
The purpose of this study is to compare the clinical and radiographic outcomes of two different barrier membranes-amnion-chorion membranes (ACM) and conventional collagen membranes-used in guided bone regeneration (GBR)…
- Trial name
- NCT07032259
- Testing
- BioXclude Amnion Chorion Membrane, Collagen Membrane
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Hyperglycemia, Dyslipidemias
The Effects of Fresh Mango Consumption on Cardiometabolic Outcomes in Free-living Individuals With Prediabetes
The goal of this clinical trial is to test the effect of 12 weeks of 1.5 cups per day of fresh mango on glucose control, insulin resistance, lipids, inflammation, oxidation and body composition in individuals with prediabetes.
- Conditions
- Hyperglycemia, Dyslipidemias, Insulin Resistance, Inflammation
- Trial name
- NCT06159543
- Testing
- Mango
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Loma Linda University
Cognition, Immunity
Immune and Cognitive Benefits of Mango Intake in Young Adults
The main objectives of our proposed study are to determine the effects of mango consumption on immune and cognitive functions in free-living college going young adults aged 18-30 years
- Trial name
- NCT06229262
- Testing
- Mango group
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Iron Deficiency Anemia
Daily Iron vs Every-other-day Iron for Pediatric Patients With IDA
Iron Deficiency Anemia (IDA) is a prevalent global health issue affecting a significant proportion of the population, including children.
- Trial name
- NCT06550362
- Testing
- iron sulfate
- Volunteers
- 100 people
- Sponsor
- Loma Linda University
Testicular Cancer
Patient Reported Experiences With Sparing External Oblique Fascia Vs Standard Inguinal Orchiectomy
The purpose of this study is to evaluate the difference in patient-reported postoperative outcomes between two standard-of-care surgical techniques for radical orchiectomy (inguinal orchiectomy versus external oblique fascia…
- Trial name
- PRESERVE (NCT06828185)
- Testing
- Radical inguinal orchiectomy, Radical external oblique fascia sparing orchiectomy
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Loma Linda University
Intensive Care Unit ICU, Intubation
The Effects of Endotracheal Suctioning on Pain and Serum Markers
The goal of this experimental study is to understand if endotracheal tube (ETT) suctioning increases pain and causes stress on the body in intubated adult ICU patients.
- Conditions
- Intensive Care Unit ICU, Intubation, Critical Illness, Mechanical Ventilation
- Trial name
- NCT06692400
- Testing
- endotracheal tube suctioning
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Loma Linda University
Gingival Inflammation, Dental Caries
Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences
Objectives: To evaluate the effectiveness of toothpaste tablets when compared to conventional dentifrices in removing plaque. Methods: 50 participants are randomized into two groups: Denttabs toothpaste tablets (T) and Colgate's…
- Trial name
- NCT07124533
- Testing
- Toothpaste Tablet, Conventional Toothpaste
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Sleep Disorders in Children
Melatonin Adolescent Research Study
The present study will use a within-person, randomized cross-over experimental design to test the effects of exogenous melatonin supplementation on the sleep and daytime functioning of typically developing adolescents with short…
- Trial name
- MARS (NCT04588233)
- Testing
- Melatonin
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Loma Linda University
Menstruation Disorders, Menstrual Cramps
Impact of Seed Cycling on Menstrual Regularity, Dysmenorrhea, and Premenstrual Symptoms
The purpose of this research is to investigate the impact of seed cycling on menstrual regularity, cramps, and pre-menstrual symptoms in women with an irregular menstrual cycle and/or dysmenorrhea.
- Conditions
- Menstruation Disorders, Menstrual Cramps, Menstruation
- Trial name
- NCT07052500
- Testing
- Seed Cycling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Loma Linda University
Pregnancy Related, Breast Feeding, Exclusive
Impact of Lactation Antenatal Teaching by Clinicians and Healthcare Providers
The purpose of this study is to increase the rate of exclusive breastfeeding at 6 weeks postpartum in the Inland Empire by addressing inadequate antenatal breastfeeding education for patients.
- Trial name
- iLATCH (NCT07560553)
- Testing
- Breastfeeding Education
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Loma Linda University