Out of Hospital Cardiac ArrestCONTACNCT02934867
Out of Hospital Cardiac Arrest: Trial Assessing the Survival Impact of Phone Advice
A study testing Protocol phone advice and Usual phone advice in people with Out of Hospital Cardiac Arrest, run by Centre Hospitalier Universitaire de Besancon at 19 sites in France.
Trial summary
Medical call center have no phone advice protocol within out of hospital cardiac arrest in France. The purpose of the present study is to compare a group of patients with protocol phone advice delivered by the dispatchers ("CONTARM" group) versus usual phone advice ( "CONTHAB" group). Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Out of Hospital Cardiac Arrest
- What is being tested?
- Protocol phone advice and Usual phone advice
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 729 participants
- Where
- 19 sitesFrance
- Study dates
- 12 Oct 2016to 19 Oct 2021
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- > 18 years old
- initial call to 15
- out of hospital cardiac arrest
- patient proximity to witness
Who cannot join
- first aid professionals on site
- rigor mortis
- location not allowing resuscitation
- inability to realize actions or misunderstanding
- no flow > 5 minutes
Trial locations and contacts
19 sites in 1 country.
19 sites in 1 country
France19 sites
CHU Angers
Angers
CHU Besançon
Besançon
CHU Bordeaux
Bordeaux
CH Châlon sur Saône
Châlon Sur Saône
CH Colmar
Colmar
CHU Dijon
Dijon
CH Lons Le Saunier
Lons-le-Saunier
CHU Lyon
Lyon
CHU Metz
Metz
CH Montauban
Montauban
CH Mulhouse
Mulhouse
CHU Nancy
Nancy
CHU Nantes
Nantes
CHU Nîmes
Nîmes
CH Orléans
Orléans
CHU Poitiers
Poitiers
CHU Reims
Reims
CHU Strasbourg
Strasbourg
CH Troyes
Troyes
About this study
Official title: Out of Hospital Cardiac Arrest: Cluster Randomized Trial Assessing the Survival Impact of Phone Advice Delivered by Medical Call Center
Medical call center have no phone advice protocol within out of hospital cardiac arrest in France. The purpose of the present study is to compare a group of patients with protocol phone advice delivered by the dispatchers ("CONTARM" group) versus usual phone advice ( "CONTHAB" group). Comparison will be performed on survival to seven days. The hypothesis is that CONTARM group has an higher survival at seven days. A second goal is to measure the survival to 15 and 30 days. The trial is randomized, controlled and will include 2600 patients. The patients will be enrolled in 19 hospitals in France.
- Conditions
- Out of Hospital Cardiac Arrest
- Being tested
- Protocol phone advice, Usual phone advice
- Medical subject headings
- Out-of-Hospital Cardiac Arrest
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Protocol phone adviceOther
Protocol phone advice
Usual phone adviceOther
Usual phone advice
| Study group | Role | What they receive |
|---|---|---|
| CONTARM | Experimental | Protocol phone advice Receives: Other: Protocol phone advice |
| CONTHAB | Other | Usual phone advice Receives: Other: Usual phone advice |
What is being measured
The primary outcome is the main question the study is designed to answer.
7 days survival
7 days survival
Measured: 7 days
Secondary outcomes (3)
15 and 30 days survival
15 and 30 days survival
Measured: 15 and 30 days
Assessment of compliance of phone advice
Listening of phone bands to measure compliance of phone advice protocol :
- good frequency of chest compression. Binary variable (Yes or Not)
- good depth of chest compression. Binary variable (Yes or Not)
- good patient positioning. Binary variable (Yes or No).
Measured: 7 days
30 days neurological status
Cerebral performance categories scale is counting with medical file
Measured: 30 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Oct 2016 (estimated)
- Study start12 Oct 2016
- Primary completion12 Oct 2021
- Study completion19 Oct 2021
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for Out of Hospital Cardiac ArrestStudies of the same condition, open and under way.
- More trials run by Centre Hospitalier Universitaire de BesanconThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 729 participants (actual)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Universitaire de Besancon
- Sponsor type
- University, hospital or other
- Collaborators
- Centre Hospitalier Universitaire Dijon, Central Hospital, Nancy, France, University Hospital, Metz, University Hospital, Strasbourg, France, Reims University hospital, Centre Hospitalier de Lons Le Saunier, Groupe Hospitalier de la Region de Mulhouse et Sud Alsace, Centre Hospitalier de Colmar, Centre Hospitalier de Troyes, Centre Hospitalier de Chalon sur Saône, Centre Hospitalier Universitaire de Nīmes, Nantes University Hospital, University Hospital, Bordeaux, Hospices Civils de Lyon, Poitiers University Hospital, University Hospital, Angers, University Hospital, Orléans, Centre Hospitalier de Montauban
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02934867
- Sponsor's protocol ID
- CONTAC R/2015/50
- Acronym
- CONTAC
- Status last verified
- Jan 2020
- First submitted
- 26 Jul 2016
- Last updated
- 16 Jan 2025
- Results posted
- No
- Data monitoring committee
- No
Publications
Berg RA, Hemphill R, Abella BS, Aufderheide TP, Cave DM, Hazinski MF, Lerner EB, Rea TD, Sayre MR, Swor RA. Part 5: adult basic life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2010 Nov 2;122(18 Suppl 3):S685-705. doi: 10.1161/CIRCULATIONAHA.110.970939.
PubMed 20956221Nolan JP, Soar J, Zideman DA, Biarent D, Bossaert LL, Deakin C, Koster RW, Wyllie J, Bottiger B; ERC Guidelines Writing Group. European Resuscitation Council Guidelines for Resuscitation 2010 Section 1. Executive summary. Resuscitation. 2010 Oct;81(10):1219-76. doi: 10.1016/j.resuscitation.2010.08.021. No abstract available.
PubMed 20956052Koster RW, Baubin MA, Bossaert LL, Caballero A, Cassan P, Castren M, Granja C, Handley AJ, Monsieurs KG, Perkins GD, Raffay V, Sandroni C. European Resuscitation Council Guidelines for Resuscitation 2010 Section 2. Adult basic life support and use of automated external defibrillators. Resuscitation. 2010 Oct;81(10):1277-92. doi: 10.1016/j.resuscitation.2010.08.009. No abstract available.
PubMed 20956051Desmettre T, Jenvrin J, Freysz M, Nace L, Puyraveau M, Berthier F, Dreyfus P, Philippe MH, Labourey JM, Capellier G. Drug prescription at the medical call center. Ann. Fr. Med. Urgence (2013) 3:14-19.
Sigaux A, Jonquet S, Puyraveau M, Bretillot L, Labourey JM, Capellier G, Desmettre T. Evaluation of phone advice delivered by a medical call center in case of cardiac arrest. Ann. Fr. Med. Urgence (2014) 4:11-17.
Study at a glance
From the registry record, last updated by the sponsor on 16 Jan 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Out of Hospital Cardiac Arrest: Cluster Randomized Trial Assessing the Survival Impact of Phone Advice Delivered by Medical Call Center
- ClinicalTrials.gov ID
- NCT02934867
- Acronym / sponsor ID
- CONTAC / CONTAC R/2015/50
- Conditions
- Out of Hospital Cardiac Arrest
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 729 participants (actual)
- Lead sponsor
- Centre Hospitalier Universitaire de BesanconUniversity, hospital or other
- Collaborators
- Centre Hospitalier Universitaire Dijon, Central Hospital, Nancy, France, University Hospital, Metz, University Hospital, Strasbourg, France, Reims University hospital, Centre Hospitalier de Lons Le Saunier, Groupe Hospitalier de la Region de Mulhouse et Sud Alsace, Centre Hospitalier de Colmar, Centre Hospitalier de Troyes, Centre Hospitalier de Chalon sur Saône, Centre Hospitalier Universitaire de Nīmes, Nantes University Hospital, University Hospital, Bordeaux, Hospices Civils de Lyon, Poitiers University Hospital, University Hospital, Angers, University Hospital, Orléans, Centre Hospitalier de Montauban
- Study start
- 12 Oct 2016 (actual)
- Primary completion
- 12 Oct 2021 (actual)
- Study completion
- 19 Oct 2021 (actual)
- First posted
- 17 Oct 2016 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Medical call center have no phone advice protocol within out of hospital cardiac arrest in France. The purpose of the present study is to compare a group of patients with protocol phone advice delivered by the dispatchers ("CONTARM" group) versus usual phone advice ( "CONTHAB" group). Comparison will be performed on survival to seven days. The hypothesis is that CONTARM group has an higher survival at seven days. A second goal is to measure the survival to 15 and 30 days. The trial is randomized, controlled and will include 2600 patients. The patients will be enrolled in 19 hospitals in France.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| CONTARM | Experimental | Other: Protocol phone adviceProtocol phone advice |
| CONTHAB | Other | Other: Usual phone adviceUsual phone advice |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- > 18 years old
- initial call to 15
- out of hospital cardiac arrest
- patient proximity to witness
Key exclusion criteria (5 listed)
- first aid professionals on site
- rigor mortis
- location not allowing resuscitation
- inability to realize actions or misunderstanding
- no flow > 5 minutes
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Protocol phone adviceProtocol phone advice | Other | CONTARM |
| Usual phone adviceUsual phone advice | Other | CONTHAB |
Primary outcome
7 days survival
Time frame: 7 days
7 days survival
3 secondary outcomes
15 and 30 days survival
Time frame: 15 and 30 days
Assessment of compliance of phone advice
Time frame: 7 days
30 days neurological status
Time frame: 30 days
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Jan 2025.
- Background: PubMed 20956221Berg RA, Hemphill R, Abella BS, Aufderheide TP, Cave DM, Hazinski MF, Lerner EB, Rea TD, Sayre MR, Swor RA. Part 5: adult basic life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2010 Nov 2;122(18 Suppl 3):S685-705. doi: 10.1161/CIRCULATIONAHA.110.970939.
- Background: PubMed 20956052Nolan JP, Soar J, Zideman DA, Biarent D, Bossaert LL, Deakin C, Koster RW, Wyllie J, Bottiger B; ERC Guidelines Writing Group. European Resuscitation Council Guidelines for Resuscitation 2010 Section 1. Executive summary. Resuscitation. 2010 Oct;81(10):1219-76. doi: 10.1016/j.resuscitation.2010.08.021. No abstract available.
- Background: PubMed 20956051Koster RW, Baubin MA, Bossaert LL, Caballero A, Cassan P, Castren M, Granja C, Handley AJ, Monsieurs KG, Perkins GD, Raffay V, Sandroni C. European Resuscitation Council Guidelines for Resuscitation 2010 Section 2. Adult basic life support and use of automated external defibrillators. Resuscitation. 2010 Oct;81(10):1277-92. doi: 10.1016/j.resuscitation.2010.08.009. No abstract available.
- BackgroundDesmettre T, Jenvrin J, Freysz M, Nace L, Puyraveau M, Berthier F, Dreyfus P, Philippe MH, Labourey JM, Capellier G. Drug prescription at the medical call center. Ann. Fr. Med. Urgence (2013) 3:14-19.
- BackgroundSigaux A, Jonquet S, Puyraveau M, Bretillot L, Labourey JM, Capellier G, Desmettre T. Evaluation of phone advice delivered by a medical call center in case of cardiac arrest. Ann. Fr. Med. Urgence (2014) 4:11-17.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
19 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Protocol phone advice and Usual phone advice in people with Out of Hospital Cardiac Arrest, run by Centre Hospitalier Universitaire de Besancon at 19 sites in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 16 Jan 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 19 sites in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
7 days survival (time frame: 7 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT02934867, which also lists 5 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jan 2025.