Clinical trials: Cervical Ripening
Labour Onset and Length Abnormalities, Labor; Forced or Induced, Affecting Fetus or Newborn
Dilapan-S/Dilasoft E-Registry in Induction of Labor
International Observational E-Registry on the use of DILAPAN-S® osmotic dilator / DILASOFT® osmotic dilator for cervical ripening prior to labour induction.
- Trial name
- DSREGISTRYIL (NCT02318173)
- Testing
- Dilapan-S
- Where
- 11 sites in United States, Czechia and 5 more
- Volunteers
- 444 people
- Sponsor
- Medicem International CR s.r.o.
Induction of Labor Affected Fetus / Newborn
Cervical Ripening With a Double-lumen Balloon Catheter for Six Versus Twelve Hours
The Foley catheter is a safe, effective method for cervical ripening. Limited data exists to indicate ideal time of placement for optimal cervical ripening prior to induction.
- Trial name
- NCT03086967
- Testing
- Double-lumen balloon catheter
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Wake Forest University Health Sciences
Pregnancy, Labor, Induced
Labor Induction With Oral Versus Vaginal Misoprostol
This study will compare vaginal and oral misoprostol, to determine whether a vaginal misoprostol regimen achieves a higher vaginal delivery rate in a real-world, high-volume setting, and whether this regimen reduces time and…
- Trial name
- NCT04755218
- Where
- United States
- Volunteers
- 2,546 people
- Sponsor
- University of Texas Southwestern Medical Center
Pregnancy
Outpatient Cervical Ripening
The process of labor induction can mean several hours or even days spent as an inpatient prior to delivery. These prolonged hospital admissions contribute to increased financial burden on both patients and hospital systems…
- Trial name
- NCT04041687
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Prisma Health-Upstate
Obesity, Pregnancy
Randomized Controlled Trial: Induction of Labour of Obese Women With Dinoprostone or Single Balloon Catheter
The purpose of this study is to compare the efficacy of single balloon foley catheters to dinoprostone for the induction of labour of obese women.
- Conditions
- Obesity, Pregnancy, Labor, Induced
- Trial name
- NCT01962831
- Testing
- Dinoprostone, Single balloon foley catheter
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Saskatchewan Health Authority - Regina Area
Uterine Cervical Incompetence
Dilapan-S Osmotic Dilator in Pre-induction of Labor
Non-interventional prospective data collection designed to evaluate clinical outcome on the efficacy of the use of Dilapan-S in the indication of labor pre-induction in women with/without a history of Caesarean section.
- Trial name
- NCT02098382
- Testing
- Dilapan-S
- Where
- Czechia
- Volunteers
- 125 people
- Sponsor
- Medicem International CR s.r.o.
Labor, Induced
A Randomized, Control Trial for Preinduction Cervical Ripening
The goal of this study is to compare the vaginal delivery rates in women undergoing induction of labor with an unripe cervix between oxytocin induction alone and preinduction cervical ripening with prostaglandin El (misoprostol).
- Trial name
- NCT00393731
- Testing
- Misoprostol, oxytocin
- Where
- United States
- Volunteers
- 540 people
- Sponsor
- The University of Texas Health Science Center, Houston
Abortion, Induced
Mifepristone Versus Laminaria for Cervical Ripening in Midtrimester Induction
Data from other countries have suggested that oral mifepristone used as a cervical ripening agent may decrease induction to delivery time in midtrimester inductions.
- Trial name
- NCT00383032
- Testing
- mifepristone
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Induction of Labor Affected Fetus / Newborn
Nitroglycerin Skin Patches for Facilitating Cervical Ripening: A Randomized Controlled Trial
This study aims to establish the efficacy of transdermal glyceryl trinitrate as a nitric oxide donor in addition to dinoprostone for induction of cervical ripening in the third trimester through progression in the Bishop's score…
- Trial name
- NCT03320187
- Testing
- Nitroderm TTS, Dinoprostone
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Pregnancy Complications
Semi-permanent Acupuncture Effect on Cervical Ripening
Cervical ripening is a medical treatment that can cause physical or emotional discomfort in pregnant women and is not without risks.
- Trial name
- NCT06357962
- Testing
- Semi-permanent acupuncture
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Cervical Ripening and Induction of Labor
Cervical Ripening: A Comparison Between Intravaginal Misoprostol Tablet and Intracervical Foley's Catheter and Subsequent Induction of Labor, Safety and Efficacy in Federal Teaching Hospital Abakaliki, Ebonyi State, Nigeria.
The aim of this study is to compare the effectiveness and safety of Foley's catheter and misoprostol in cervical ripening.
- Trial name
- NCT02574338
- Testing
- Foley's Catheter, prostaglandin E1 analogue
- Where
- Nigeria
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Nwali Matthew Igwe
Pregnancy, Labor, Induced
Foley Bulb With Oral Misoprostol for Induction of Labor
Induction of labor is associated with increased cesarean delivery rates, particularly in women with an unfavorable cervix. Both pharmacologic and mechanical methods are utilized for cervical ripening and labor induction.
- Trial name
- NCT03407625
- Testing
- Foley bulb plus Oral Misoprostol, Oral Misoprostol
- Where
- United States
- Volunteers
- 2,227 people
- Sponsor
- University of Texas Southwestern Medical Center
Labour,Induced
Oral Misoprostol Solution in Labor Induction
This study compares safety and efficacy between repetitive hourly dose of oral misoprostol and two hourly dose oral regimens for cervical ripening and labor induction.
- Trial name
- NCT03927807
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Labour; Induced, Pilot Study
High Volume Foleys Increasing Vaginal Birth Pilot Trial
It is currently unknown if there is a way to decrease the risk of cesarean delivery when undergoing cervical ripening and induction of labour.
- Conditions
- Labour; Induced, Pilot Study, Cervical Ripening
- Trial name
- NCT02993432
- Testing
- Foley catheter filled to 80cc, prostaglandin of the clinician's choice
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Cervical Dilation
Balloon Catheter for Cervical Ripening
Once admitted, women who will have a transcervical balloon catheter inserted for induction will be approached for participation in this study.
- Trial name
- 25148 (NCT02606643)
- Testing
- Slight traction, Foley Catheter to no traction
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- St. Louis University
Pregnancy Related, Labor
Inpatient Versus Outpatient Cervical Ripening
Induction of labor is a process of stimulating uterine contractions before the onset of labor, with a goal of achieving vaginal birth.
- Conditions
- Pregnancy Related, Labor, Induction, Cervical Ripening
- Trial name
- NCT03769610
- Testing
- Inpatient Foley catheter, Outpatient Foley catheter
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- LifeBridge Health
Induction of Labor
Cervical Foley Plus Vaginal Misoprostol for Labor Induction
The purpose of this study is to compare the efficacy of the combination of the supracervical foley bulb and vaginal misoprostol to vaginal misoprostol alone for labor induction.
- Trial name
- NCT01279343
- Testing
- Foley bulb
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Cervical Ripening, Induction of Labor
Heated Saline in Cervical Balloon for Labor Induction, a RCT
This study is a single-center, randomized, two-arm, controlled trial, including women requiring cervical ripening during the process Induction of Labor using Balloon catheter (BC).
- Conditions
- Cervical Ripening, Induction of Labor, Unfavorable Cervix, Mechanical Method
- Trial name
- NCT05864326
- Testing
- Warm group, Room temperature group
- Where
- Switzerland
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Begona Martinez de Tejada
Induction of Labor Affected Fetus / Newborn
Dilapan-S® for Induction of Labor The Feasibility Study
This is a prospective feasibility study to investigate Dilapan-S® as an outpatient method of cervical ripening in low risk pregnancies >=39 weeks.
- Trial name
- DILATE (NCT04521062)
- Testing
- Dilapan S
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Failed Induction of Labor
Comparison Between Ultrasonographic Cervical Length and Bishop Score in Preinduction Cervical Assessment
To compare the ultrasonographic cervical length with the Bishop score in determining the administration of prostaglandin for preinduction cervical ripening in nulliparas at term.
- Trial name
- NCT01317706
- Testing
- Assessment of cervical status
- Where
- South Korea
- Volunteers
- 154 people
- Sponsor
- Seoul National University Hospital