Clinical trials: Drug Application
Cerebral Palsy, Mental Retardation
Development and Application of a Diagnosis and Treatment System for Children's Brain Diseases Based on Knowledge Graphs and Large Models
Using the knowledge graph and big model technology of combining Chinese and Western medicine we construct a popularization and prevention system for childhood encephalopathy an assisted decision-making system for childhood…
- Conditions
- Cerebral Palsy, Mental Retardation, Tourette's Syndrome, Attention Deficit Hyperactivity Disorder
- Trial name
- NCT06848959
- Testing
- No intervention
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Yun Liu,PhD
Respiratory Disease
The Efficiency of Chest Physiotherapy Applied in a Different Order
This study intends to compare the impact of chest physiotherapy applied with two different methods on physiologic parameters in children hospitalized in the intensive care unit.
- Trial name
- NCT05022082
- Testing
- Chest Physiotherapy- Aspiration- Inhaler drugs group
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Selmin Kose
Epistaxis
Effect of Practical Demonstration to Use Nasal Spray and Apply Intranasal Ointment on Epistaxis
To compare the result of verbally educating the parents about method of intranasal antiseptic cream application versus practically educating and demonstrating how to apply cream intra nasally.
- Trial name
- NCT04217941
- Testing
- Health education with practical demonstration of nasal ointment, Health Education and practical demonstration of Nasal spray and intranasal ointment
- Where
- Pakistan
- Volunteers
- 300 people
- Sponsor
- Combined Military Hospital, Pakistan
Rotator Cuff Tear
Study on the Application of Shock Wave Technique After Rotator Cuff Operation
This study is a prospective cohort study and is a single-center clinical trial. The subjects of this study were patients who underwent rotator cuff repair in the Department of Sports Medicine and the Department of Rehabilitation…
- Trial name
- NCT06563739
- Testing
- Divergent low energy shock wave, Divergent medium and low energy shock wave, Focused low energy shock wave
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking University Third Hospital
Medication Related Osteonecrosis of the Jaw
MRONJ and Polynucleotides-Hyaluronic Acid Hydrogel (Regenfast®)
Several circumstances or conditions, such as wound extension or disease, can affect the hard and soft tissue healing after surgical treatment of MRONJ. Supportive therapies are therefore needed to help tissues wound healing.
- Trial name
- REG-MRONJ-1 (NCT06984107)
- Testing
- MRONJ resection plus PN+HA
- Volunteers
- 10 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Infection, Meningitis
Pediatric Infectious Disease Precision Medicine Using Sequencing Evaluation of CSF
Prospective, multi-site, study to evaluate the diagnosis rate of DNA and RNA sequencing of cerebrospinal fluid for identification of pathogens directly in patients who have already had a spinal tap to evaluate for infection and…
- Trial name
- PIPSEC (NCT03796546)
- Where
- 3 sites in United States
- Volunteers
- 71 people
- Sponsor
- IDbyDNA, Inc.
Adenocarcinoma, Ovarian Neoplasms
Testing Drug Sensitivity of Ovarian, Fallopian and Primary Peritoneal Adenocarcinomas
2.0 Study Objectives: 2.1 To evaluate the ability of the MiCK assay to predict the outcome of chemotherapy of cancer patients for first-line treatment.
- Conditions
- Adenocarcinoma, Ovarian Neoplasms, Fallopian Tube Neoplasms, Peritoneal Neoplasms
- Trial name
- NCT00443196
- Testing
- MiCK Assay
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Pierian Biosciences
Medication Management
An Interventional Study to Establish a Medication Management Mobile Application for Pediatric Surgery Patients
An interventional study that aims to design, establish and implement an electronic application for management of the usage of anesthetics, antimicrobials, and analgesics in a pediatric surgery department, and assess the impact of…
- Trial name
- NCT06018662
- Testing
- A medication management mobile application
- Where
- Egypt
- Volunteers
- 276 people
- Sponsor
- Ain Shams University
Hypogonadism
A Study Using Recombinant Human Luteinizing Hormone (r-hLH, Luveris®) in the Treatment of Chinese Women With Hypogonadotropic Hypogonadism
This was a prospective, open, non-comparative study to evaluate the safety and efficacy of recombinant human luteinizing hormone (rhLH, Luveris) administered subcutaneously (s.c.) in follicular development during ovulation…
- Trial name
- NCT01084265
- Testing
- Recombinant human luteinizing hormone (r-hLH), Recombinant human follicle-stimulating hormone (r-hFSH), Human chorionic gonadotropin (hCG)
- Where
- China
- Volunteers
- 31 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Pain
Local Flurbiprofen to Treat Pain Following Wisdom Tooth Extraction
This study will evaluate the effectiveness of the non-steroidal anti-inflammatory drug flurbiprofen (Ansaid® (Registered Trademark)) in relieving pain following oral surgery.
- Trial name
- NCT00001724
- Testing
- Flurbiprofen
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Febrile Infection, Anthrax
Febrile Whole Blood Specimen Collection and Testing
Whole blood samples will be collected from febrile patients presenting with fever of unknown origin and flu-like syndromes. Collection sites will consent patients and collect one (1) 4 mL whole blood sample from adults and either…
- Trial name
- NCT03498027
- Testing
- TaqMan Bacillus anthracis Detection Kit
- Where
- 3 sites in United States
- Volunteers
- 97 people
- Sponsor
- MRI Global
Lymphedema, Lymphatic Disorders
Imaging Lymphatic Function in Normal Subjects and in Persons With Lymphatic Disorders
The purpose of this study is to demonstrate the feasibility of near-infrared fluorescence imaging in subjects with acquired or hereditary lymphedema, in subjects with lipidema and other lymphovascular disorders and in normal…
- Conditions
- Lymphedema, Lymphatic Disorders, Lipedema, Vascular Malformation
- Trial name
- NCT00833599
- Testing
- NIRFLI with ICG
- Where
- 3 sites in United States
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Health Knowledge Attitudes and Practice
Evidence Based Medicine in General Practice
Evidence-based medicine (EBM) is the basis of work for physicians- practitioners in all specialties, including family medicine. Various issues in diagnosis, treatment and prognosis appear in daily work with patients and a…
- Trial name
- EBMINGP (NCT01801683)
- Testing
- Intervention-using PEARLS
- Volunteers
- 98 people
- Sponsor
- University of Split
Acne
Anti-acne Efficacy of a Dermo-cosmetic Product Associated With the Fixed Combination Adapalene 0.1%/ Benzoyl Peroxide 2.5% Treatment Versus This Treatment Associated With a Standard Moisturizer in Male and Female Subjects Presenting With Mild to Moderate Acne
Study to evaluate the anti-acne efficacy of a dermo-cosmetic associated with the fixed combination Adapalene 0.1%/ benzoyl peroxide 2.5% treatment and to demonstrate that the dermo-cosmetic product can improve the local tolerance…
- Trial name
- NCT03832647
- Testing
- Epiduo, Salicylic Acid, Hydréane légère
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Vichy Laboratoires
Poisoning Patients
Medicine Acuity Patching Combined Massage in the Treatment of Patients With Acute Poisoning
This topic in western medicine combined on the basis of gastric lavage therapy in patients with acute poisoning acupoint sticking of traditional Chinese medicine and acupuncture point massage treatment, aims to smoothly…
- Trial name
- NCT04941859
- Testing
- acupoint massage and application
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Inappropriate Prescribing
Using a Mobile Application as a Support at the Prescription of Appropriate Medications for Elderly
Objective: To develop and evaluate the effectiveness of a mobile application to support decision making for prescription drugs to elderly patients.
- Trial name
- NCT02918643
- Testing
- Use of an application to for mobile devices like decision-making support for prescription drugs to elderly patients
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Bahia
Medication Safety, Preventable Medication Harm
Clinical Pharmacist Impact Study
This study evaluated a pharmacist-led medication-safety program in hospitalized patients. The program included routine inpatient medication review and the use of smartphone-based clinical decision-support applications to identify…
- Conditions
- Medication Safety, Preventable Medication Harm, Pharmacotherapy Optimization
- Trial name
- NCT07269002
- Testing
- Pharmacist-Led Medication Safety Program
- Where
- Egypt
- Volunteers
- 3,600 people
- Sponsor
- Beni-Suef University
Cardiac and Respiratory Arrest
SST in Emergency Education
This study looks back at how the investigatorsll two different teaching methods work for training medical and nursing students in CPR (cardiopulmonary resuscitation), a life-saving emergency procedure used when someone's heart…
- Trial name
- SST (NCT07803861)
- Testing
- case-based scenario simulation teaching
- Where
- China
- Volunteers
- 69 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Scalp Psoriasis
Safety Study in Patients With Scalp Psoriasis Suppression Following Maximal Use Treatment With Topical Product
An Open-Label, Safety Study to Assess the Potential for Adrenal Suppression Following Maximal Use DSXS topical product (Taro Pharmaceuticals U.S.A., Inc.) in Patients with Moderate to SevereScalp Psoriasis
- Trial name
- NCT02933502
- Testing
- DSXS topical product
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Utilization of Software Application Features
Efficacy of the Pre-Admission Medication List (PAML) Builder Reminder Prompts
This project will study whether reminder prompts increase PAML Builder application feature utilization.
- Trial name
- PAMLTIPS (NCT00657462)
- Testing
- Reminders
- Where
- 2 sites in United States
- Volunteers
- 14,122 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital