Clinical trials: sponsored by University of Bern
Contrast Enhanced Ultrasound, Ultrasonic Diagnosis
International Delphi Study to Develop Standardized Quality Criteria and a Rating Tool for Liver CEUS Image Quality Assessment
This study aims to establish international consensus-based quality criteria for contrast-enhanced ultrasound (CEUS) examinations of the liver and to develop a standardized tool for assessing CEUS image and examination quality.
- Conditions
- Contrast Enhanced Ultrasound, Ultrasonic Diagnosis, Liver
- Trial name
- ICON LiverCEUS (NCT07656181)
- Where
- Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Bern
Childhood Cancer
Swiss Childhood Cancer Survivor Study
The SCCSS is designed to investigate which long-term effects childhood cancer and its treatment have on survivors, and includes those who were under 20 years when they were diagnosed.
- Trial name
- SCCSS (NCT03297034)
- Where
- Switzerland
- Volunteers
- 4,136 people, healthy volunteers welcome
- Sponsor
- University of Bern
Asthma, Wheezing
Swiss Paediatric Airway Cohort
The Swiss Paediatric Airway Cohort (SPAC) is a national, prospective clinical cohort of children and adolescents who visit physicians in Switzerland for recurrent wheeze, cough, and exercise- or sleep-related respiratory…
- Conditions
- Asthma, Wheezing, Cough, Exercise Induced Bronchospasm
- Trial name
- SPAC (NCT03505216)
- Where
- 12 sites in Austria, Switzerland
- Volunteers
- 6,000 people
- Sponsor
- University of Bern
Mental Health Issue, Transdiagnostic Mechanisms
Efficacy of a Transdiagnostic Online Prevention Approach in Adolescents (EMPATIA)
The goal of this randomized controlled clinical trial is to investigate the efficacy of the internet-delivered intervention EMPATIA on general psychopathology of adolescents with subclinical symptoms compared to a Care As Usual…
- Conditions
- Mental Health Issue, Transdiagnostic Mechanisms, Adolescent Psychology, Prevention
- Trial name
- EMPATIA (NCT05934019)
- Testing
- EMPATIA 1
- Where
- Switzerland
- Volunteers
- 158 people
- Sponsor
- University of Bern
Alcohol Use Disorder (AUD), Cocaine Use Disorder (CUD)
Web-based Alcohol- or Cocaine-specific Inhibition Training in Adolescents and Young Adults With Substance Use Disorder
Substance misuse is one of the most common risk factors for health problems and premature death among adolescents and young adults worldwide.
- Conditions
- Alcohol Use Disorder (AUD), Cocaine Use Disorder (CUD), Substance Use Disorder (SUD)
- Trial name
- WAIT-AYA (NCT07071779)
- Testing
- Substance-specific inhibition training, Control training
- Where
- Switzerland
- Volunteers
- 210 people
- Sponsor
- University of Bern
Cerebral Palsy
Swiss Cerebral Palsy Registry
The Swiss-CP-Reg is a national patient registry that collects information on diagnosis, symptoms, treatment and follow-up of patients with cerebral palsy (CP) in Switzerland.
- Trial name
- Swiss-CP-Reg (NCT04992871)
- Where
- 12 sites in Switzerland
- Volunteers
- 15,000 people
- Sponsor
- University of Bern
Pandemic, COVID-19, Infections
Bern, Get Ready (BEready) Cohort Study for Pandemic Preparedness
The BEready project aims to find out how people in the Canton of Bern can be helped to be more prepared for the next pandemic. BEready wants to understand how infections spread among people as well as between people and animals.
- Conditions
- Pandemic, COVID-19, Infections, Zoonoses, Epidemic Disease
- Trial name
- BEready (NCT06739499)
- Where
- Switzerland
- Volunteers
- 2,157 people, healthy volunteers welcome
- Sponsor
- University of Bern
Dental Implant Failure
Variables for Long-term Success in Implant Dentistry
The aims of the present retrospective 25-year study of a sample of 459 patients with 753 sandblasted and acid-etched (SLA) titanium oral implants are: to assess the clinical parameters at SLA implants after 25 years in function…
- Trial name
- NCT06599320
- Testing
- Oral rehabilitation with dental implants
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Bern
SMA, DMD
Swiss Registry for Neuromuscular Disorders
The Swiss Patient Registry for DMD/BMD and SMA was launched in 2008 in order to give Swiss patients access to new therapies. It was founded with the financial support of several patient organizations and research foundations.
- Conditions
- SMA, DMD, BMD, IMD
- Trial name
- Swiss-Reg-NMD (NCT05102916)
- Where
- 19 sites in Switzerland
- Volunteers
- 2,000 people
- Sponsor
- University of Bern
Primary Ciliary Dyskinesia, Kartagener Syndrome
The Ear-Nose-Throat (ENT) Prospective International Cohort of PCD Patients (EPIC-PCD)
The Ear-Nose-Throat (ENT) Prospective International Cohort of patients with Primary Ciliary Dyskinesia (EPIC-PCD) is a prospective observational clinical cohort study, set up as a multinational multi-centre study.
- Trial name
- EPIC-PCD (NCT04611516)
- Where
- Switzerland
- Volunteers
- 1,000 people
- Sponsor
- University of Bern
Primary Ciliary Dyskinesia
Living With Primary Ciliary Dyskinesia (Living With PCD)
Living with PCD (formerly COVID-PCD) is a participatory research project that aims to answer emerging questions about primary ciliary dyskinesia (PCD) in order to improve the health and quality of life of people with PCD.
- Trial name
- NCT04602481
- Where
- Switzerland
- Volunteers
- 1,500 people
- Sponsor
- University of Bern
Rare Diseases
Swiss Rare Disease Registry (SRDR)
The SRDR is a national registry that records rare diseases in people of any age who live in Switzerland. It serves as a platform for scientists, health professionals, affected people, and politicians.The SRDR aims to collect…
- Trial name
- SRDR (NCT05179863)
- Where
- 20 sites in Switzerland
- Volunteers
- 500,000 people
- Sponsor
- University of Bern
Primary Ciliary Dyskinesia, Kartagener Syndrome
International Primary Ciliary Dyskinesia Cohort
The iPCD Cohort is an international cohort that assembles available retrospective datasets and prospectively newly collected clinical and diagnostic data from patients suffering from primary ciliary dyskinesia (PCD) worldwide, to…
- Trial name
- iPCD (NCT03517865)
- Where
- Switzerland
- Volunteers
- 3,400 people
- Sponsor
- University of Bern
Primary Ciliary Dyskinesia, Kartagener Syndrome
Swiss Primary Ciliary Dyskinesia Registry
The Swiss Primary Ciliary Dyskinesia (PCD) Registry is a national patient registry that collects information on diagnosis, symptoms, treatment and follow-up of patients with PCD in Switzerland and provides data for national and…
- Trial name
- CH-PCD (NCT03606200)
- Where
- Switzerland
- Volunteers
- 800 people
- Sponsor
- University of Bern
Hiv
HIV-1 Subtype-specific Drug Resistance in Patients Failing Dolutegravir (DTG) Based Regimen
This is a prospective observational study enrolling People Living with HIV (PLHIV) who are on a Dolutegravir-based AntiRetroviral Treatment (ART) regimen and experiencing virologic failure.
- Trial name
- DTG-Resist (NCT06285110)
- Where
- 22 sites in Argentina, Brazil and 14 more
- Volunteers
- 1,103 people
- Sponsor
- University of Bern
Caries
Effect of the Use of Xylitol Gum in the Prevention of Caries Lesions in Children Living in Ladakh
Background: Ladakh is a region administered by India, covering an area slightly larger than Croatia; it is part of the larger region of Kashmir and Jammu.
- Trial name
- CaPreXCh (NCT04420780)
- Testing
- Administration of sugar-free gums sugar-free gums containing 100% Xylitol as sweetener, Administration of sugar-free gums sugar-free gums containing containing a polyols mixture plus a low amount of Xylitol (22%)
- Where
- Russia
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Bern
Dental Caries, Dental Plaque
RCT on Effectiveness of Oral Health Preventive Programmes in School Children in Uganda
Dental caries represents a challenge for Oral Health Services in several African Countries, like Uganda. Few studies have been reported the burden of oral health, its prevention and non-operative treatment among school children…
- Conditions
- Dental Caries, Dental Plaque, Dental Diseases, Dental Caries in Children
- Trial name
- NCT06081868
- Testing
- Use of toothbrush/toothpaste/fluoride varnish, Education on nutrition/oral hygiene
- Where
- Switzerland
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- University of Bern
Late Effect, Childhood Cancer
The Swiss Childhood Cancer Survivor Study - Follow-up (SCCSS-FollowUp)
The SCCSS-FollowUp is a national, multicenter cohort study designed to investigate late effects in childhood cancer survivors in a prospective and longitudinal way.
- Trial name
- SCCSS-FU (NCT04732273)
- Testing
- Physical examination, diagnostic tests, laboratory tests, Personal history, questionnaire
- Where
- 3 sites in Switzerland
- Volunteers
- 3,000 people
- Sponsor
- University of Bern
Childhood Cancer, Cancer-related Problem/Condition
Effect of Cognitively Challenging Physical Activity on Executive Functions in Pediatric Cancer Patients
When it comes to exercise and sport for children and adolescents with cancer, there is often still the opinion that physical activity has a negative effect on the weakened body suffering from cancer.
- Conditions
- Childhood Cancer, Cancer-related Problem/Condition, Cognitive Side Effects of Cancer Therapy, Physical Activity
- Trial name
- KiKli Fit (NCT06839794)
- Testing
- Cognitively challenging physical activity for paediatric cancer patients, Physical activity recommendations
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- University of Bern
Toe Flexor Strength
Improving Foot Strength in Vocational Ballet Dancers
Professional dancers subject their feet to high forces through frequent jumping, repeated heel rises, insufficient shoe cushioning, and a high degree of foot mobility.
- Trial name
- NCT06589050
- Testing
- "Toe flexor device" experimental group, "Inclined Heel Rise" experimental group
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Bern