Clinical trials: sponsored by IRCCS Eugenio Medea
Motor Disorders, Neuromuscular Diseases
Usability of the FTEXES Wearable Textile Platform for Functional Electrical Stimulation and EMG
FTEXES (Functionalized TEXtiles for Electrical Stimulation) is a wearable platform based on sensorized garments (Smart Pants and Smart T-shirt) with integrated textile electrodes for surface electromyography (EMG) recording and…
- Conditions
- Motor Disorders, Neuromuscular Diseases, Healthy Volunteers
- Trial name
- FTEXES (NCT07922980)
- Testing
- FTEXES wearable system
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Politecnico di Milano
Friedreich Ataxia
Efficacy of Stabilometric Platform to Improve Standing Balance in Patients With Friedreich's Ataxia
The primary objective is to evaluate the potential effectiveness of an individualized intensive rehabilitation intervention using the "Prokin 252" stabilometric platform in the treatment of adolescent and adult patients with…
- Trial name
- NCT06692296
- Testing
- Balance training over stabilometric platform, Balance training by means of conventional rehabilitation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- IRCCS Eugenio Medea
Developmental Dyslexia, Reading Problem
Personalization of Visual Characters and Text-to-Speech (TTS) to Support Learning in Students With Reading Difficulties
Previous research has shown the importance of font type, size and spacing to facilitate text reading in dyslexia. A special automatized procedure was designed to select the most favorable parameters for both text visualization…
- Trial name
- NCT06947512
- Testing
- Seleggo Test
- Where
- 3 sites in Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Preterm Birth, Parent-Child Relations
Biological Underpinnings of Socio-emotional Regulation in Preterm Infants and Healthy Controls
Preterm infants (PT) often need to spend their first weeks of life in the Neonatal Intensive Care Unit (NICU) where they are exposed to several adverse conditions.
- Conditions
- Preterm Birth, Parent-Child Relations, Epigenetics
- Trial name
- NCT05253924
- Testing
- DNA methylation of target genes, EEG acquisition
- Where
- Italy
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Developmental Dyslexia, Developmental Language Disorder
Dynamic Assessment of the Risk for Language and Reading Disorders in Monolingual and Multilingual Children
The project represents the completion of a part of the recently concluded European project MultiMind, in which a computer platform called MuLiMi was developed and validated.
- Trial name
- NCT06937255
- Testing
- computerized Dynamic Assessment
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Friedreich's Ataxia, Motor Disorders
Electroencephalogram in Patients With Friedreich's Ataxia for the Study of the Structural and Functional Connectome.
Prospective, exploratory, multicenter pilot study investigating the structural and functional connectome in patients with Friedreich's Ataxia (FRDA) using high-density electroencephalogram (HD-EEG).
- Trial name
- CONNETTOMA (NCT07095062)
- Testing
- HD-EEG recordings, combined with cognitive and motor assessment
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Eugenio Medea
Spinal Cord Injury, Stroke
Investigating Techniques to Enhance the Sense of Embodiment in Immersive Virtual Reality
Embodiment is an important aspect of virtual reality because it affects how natural and engaging the experience feels and can influence performance and learning in VR-based applications, including rehabilitation [McAnally \&…
- Conditions
- Spinal Cord Injury, Stroke, Healthy
- Trial name
- NCT07870044
- Testing
- Immersive Virtual Reality Embodiment Manipulations
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Cerebral Palsy (CP), Brain Injuries
Acceptability of Paediatric Wrist Orthoses Through Co-design
The goal of this pilot interventional study (pre-post design) is to learn if a co-designed wrist-hand orthosis can improve acceptability compared to a conventional orthosis in children aged 6 to 14 years with neuromotor disorders…
- Conditions
- Cerebral Palsy (CP), Brain Injuries, Neuromotor Dysfunction
- Trial name
- NCT07861958
- Testing
- Orthosis acceptability
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- IRCCS Eugenio Medea
Stroke
Biodiversity and Human Functioning Following Acquired Cerebrovascular Lesions - Phase 1
The study aims to investigate the impact that the set of factors to which a post-stroke person is exposed during daily life can have on their health.
- Trial name
- EspertaMente (NCT07504692)
- Where
- 3 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Dr. Franco Molteni
Dystrophinopathy, Muscular Dystrophies
VirtualPark_Pediatric
The goal of this clinical trial is to assess the effects of a dual-task, multimodal training program on slowing functional motor decline in children and adolescents with neuromuscular disorders.
- Conditions
- Dystrophinopathy, Muscular Dystrophies, Congenital Myopathies
- Trial name
- NCT07580365
- Testing
- Dual-task cycling, Standard therapy
- Where
- 4 sites in Italy
- Volunteers
- 22 people
- Sponsor
- Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato
Cerebral Palsy (CP)
Clinical Improvement Due to the Home Use of Agilik in Children With Cerebral Palsy
The goal of this clinical trial is to learn if a two month training with the Agilik powered orthosis improves the knee extension or the endurance in pediatric patients with Cerebral palsy and a crouch gait.
- Trial name
- Agilik@home (NCT06622655)
- Testing
- Powered orthosis
- Where
- 6 sites in Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Eugenio Medea
Neuromotor Impairments
AI-based Model for Rehabilitation Engagement and Motor Performance Evaluation in Pediatric Patients
What is the purpose of this study? This study wants to learn how the physiological signals and movement data can help researchers understand and predict how children with neuromotor impairments engage with rehabilitation.
- Trial name
- AI-REMAP (NCT06993389)
- Testing
- Inapplicable
- Where
- Italy
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Neuromotor Impairments
AI-based Model for Rehabilitation Engagement and Motor Performance Evaluation in Pediatric Patients: A Pilot Study
What is the purpose of this study? This study aims to evaluate the usability and feasibility of an artificial intelligence-based model designed to monitor in real-time the engagement and motor performance of pediatric patients…
- Trial name
- AI-REMAP (NCT07664033)
- Testing
- Artificial Intelligence Model for Rehabilitation Engagement Monitoring
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- IRCCS Eugenio Medea
Quadriplegic Cerebral Palsy
Postural Management for Hip Luxation in Quadriplegic Cerebral Palsy
Cerebral palsy (CP) is the most common motor disability in childhood. Among these, hip luxation represents the most frequent and clinically relevant one, affecting 72% of non-ambulatory CP children.
- Trial name
- CPluxprev2020 (NCT04603625)
- Testing
- postural management
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Genetic Syndrome
I-TOPS With Patients With Genetic Syndrome SYN-TOPS
Genetic syndromes involving the central nervous system are often associated with cognitive, behavioral and communication difficulties that negatively impact adaptive functioning and quality of life.
- Trial name
- SYN-TOPS (NCT07563218)
- Testing
- Italian Tailored Online Problem-Solving (I-TOPS)
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- IRCCS Eugenio Medea
Neurodevelopmental Disorder (Diagnosis)
Transdiagnostic Dimensional Profiling of Neurodevelopmental Disorders
In recent years, the growing awareness of the multifactorial nature of neurodevelopmental disorders has stimulated interest in transdiagnostic approaches aimed at investigating underlying etiological mechanisms beyond traditional…
- Trial name
- RDoC-CRAB (NCT07544199)
- Testing
- Neuropsychological assessment
- Volunteers
- 300 people
- Sponsor
- IRCCS Eugenio Medea
Language Development, Language Development Disorders
Cortical Tracking of Speech in the First Year of Life
The goal of this observational study is to investigate early neural mechanisms underlying the processing of spoken language, specifically the phenomenon of cortical tracking, and to determine whether these mechanisms can serve as…
- Conditions
- Language Development, Language Development Disorders, Infant Development, Infant Developmental Assessment
- Trial name
- NCT07531706
- Testing
- Electrophysiological recording, Behavioral Assessment
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Upper Extremity, Child
Functional Assessment Protocol for the Upper Limb for Pediatric Age
During data acquisition a trained therapist placed reflective markers on the skin of the participants in the selected body landmarks.
- Conditions
- Upper Extremity, Child, Range of Motion, Articular
- Trial name
- NCT06400667
- Testing
- Upper limb Kinematic Assessment with Optoelectronic system
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Spine Disease, Gait
Gait Spine Functional Evaluation Protocol
The goal of this clinical trial is to develop and validate of a new protocol for multifactorial functional assessment of the kinematics of spinal and total body movements during walking by means of the optoelectronic motion…
- Trial name
- NCT06400680
- Testing
- Spine Kinematic Assessment with Optoelectronic system
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Cerebral Palsy, Gait Disorders, Neurologic
Evaluation of Outcomes of Robotics Rehabilitation in Cerebral Palsy
The use of robotic devices in rehabilitation programs can improve walking patterns by reorganizing joint kinematics. This study aims to quantify the effects of a rehabilitation program supported by the Lokomat (Hocoma) robotic…
- Trial name
- LK (NCT06594653)
- Testing
- pre treatment assesment, post treatment assessment
- Where
- Italy
- Volunteers
- 59 people
- Sponsor
- IRCCS Eugenio Medea