Clinical trials: sponsored by IRCCS Eugenio Medea
Spinal Cord Injury, Stroke
Investigating Techniques to Enhance the Sense of Embodiment in Immersive Virtual Reality
Embodiment is an important aspect of virtual reality because it affects how natural and engaging the experience feels and can influence performance and learning in VR-based applications, including rehabilitation [McAnally \&…
- Conditions
- Spinal Cord Injury, Stroke, Healthy
- Trial name
- NCT07870044
- Testing
- Immersive Virtual Reality Embodiment Manipulations
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Cerebral Palsy (CP), Brain Injuries
Acceptability of Paediatric Wrist Orthoses Through Co-design
The goal of this pilot interventional study (pre-post design) is to learn if a co-designed wrist-hand orthosis can improve acceptability compared to a conventional orthosis in children aged 6 to 14 years with neuromotor disorders…
- Conditions
- Cerebral Palsy (CP), Brain Injuries, Neuromotor Dysfunction
- Trial name
- NCT07861958
- Testing
- Orthosis acceptability
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- IRCCS Eugenio Medea
Stroke
Biodiversity and Human Functioning Following Acquired Cerebrovascular Lesions - Phase 1
The study aims to investigate the impact that the set of factors to which a post-stroke person is exposed during daily life can have on their health.
- Trial name
- EspertaMente (NCT07504692)
- Where
- 3 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Dr. Franco Molteni
Stroke
Biodiversity and Human Functioning Following Acquired Cerebrovascular Lesions - Phase 2 (EspertaMente)
Grounded in the exposome framework and the bio-psycho-social model of health, this study investigated the effects of artificial light simulating natural sunlight on autonomic regulation, cognitive-motor performance and brain…
- Trial name
- EspertaMente (NCT07758257)
- Testing
- Artificial Light
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Dr. Franco Molteni
Dystrophinopathy, Muscular Dystrophies
VirtualPark_Pediatric
The goal of this clinical trial is to assess the effects of a dual-task, multimodal training program on slowing functional motor decline in children and adolescents with neuromuscular disorders.
- Conditions
- Dystrophinopathy, Muscular Dystrophies, Congenital Myopathies
- Trial name
- NCT07580365
- Testing
- Dual-task cycling, Standard therapy
- Where
- 4 sites in Italy
- Volunteers
- 22 people
- Sponsor
- Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato
Cerebral Palsy (CP)
Clinical Improvement Due to the Home Use of Agilik in Children With Cerebral Palsy
The goal of this clinical trial is to learn if a two month training with the Agilik powered orthosis improves the knee extension or the endurance in pediatric patients with Cerebral palsy and a crouch gait.
- Trial name
- Agilik@home (NCT06622655)
- Testing
- Powered orthosis
- Where
- 6 sites in Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Eugenio Medea
Neuromotor Impairments
AI-based Model for Rehabilitation Engagement and Motor Performance Evaluation in Pediatric Patients
What is the purpose of this study? This study wants to learn how the physiological signals and movement data can help researchers understand and predict how children with neuromotor impairments engage with rehabilitation.
- Trial name
- AI-REMAP (NCT06993389)
- Testing
- Inapplicable
- Where
- Italy
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Neuromotor Impairments
AI-based Model for Rehabilitation Engagement and Motor Performance Evaluation in Pediatric Patients: A Pilot Study
What is the purpose of this study? This study aims to evaluate the usability and feasibility of an artificial intelligence-based model designed to monitor in real-time the engagement and motor performance of pediatric patients…
- Trial name
- AI-REMAP (NCT07664033)
- Testing
- Artificial Intelligence Model for Rehabilitation Engagement Monitoring
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- IRCCS Eugenio Medea
Quadriplegic Cerebral Palsy
Postural Management for Hip Luxation in Quadriplegic Cerebral Palsy
Cerebral palsy (CP) is the most common motor disability in childhood. Among these, hip luxation represents the most frequent and clinically relevant one, affecting 72% of non-ambulatory CP children.
- Trial name
- CPluxprev2020 (NCT04603625)
- Testing
- postural management
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Genetic Syndrome
I-TOPS With Patients With Genetic Syndrome SYN-TOPS
Genetic syndromes involving the central nervous system are often associated with cognitive, behavioral and communication difficulties that negatively impact adaptive functioning and quality of life.
- Trial name
- SYN-TOPS (NCT07563218)
- Testing
- Italian Tailored Online Problem-Solving (I-TOPS)
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- IRCCS Eugenio Medea
Neurodevelopmental Disorder (Diagnosis)
Transdiagnostic Dimensional Profiling of Neurodevelopmental Disorders
In recent years, the growing awareness of the multifactorial nature of neurodevelopmental disorders has stimulated interest in transdiagnostic approaches aimed at investigating underlying etiological mechanisms beyond traditional…
- Trial name
- RDoC-CRAB (NCT07544199)
- Testing
- Neuropsychological assessment
- Volunteers
- 300 people
- Sponsor
- IRCCS Eugenio Medea
Language Development, Language Development Disorders
Cortical Tracking of Speech in the First Year of Life
The goal of this observational study is to investigate early neural mechanisms underlying the processing of spoken language, specifically the phenomenon of cortical tracking, and to determine whether these mechanisms can serve as…
- Conditions
- Language Development, Language Development Disorders, Infant Development, Infant Developmental Assessment
- Trial name
- NCT07531706
- Testing
- Electrophysiological recording, Behavioral Assessment
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Spine Disease, Gait
Gait Spine Functional Evaluation Protocol
The goal of this clinical trial is to develop and validate of a new protocol for multifactorial functional assessment of the kinematics of spinal and total body movements during walking by means of the optoelectronic motion…
- Trial name
- NCT06400680
- Testing
- Spine Kinematic Assessment with Optoelectronic system
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Upper Extremity, Child
Functional Assessment Protocol for the Upper Limb for Pediatric Age
During data acquisition a trained therapist placed reflective markers on the skin of the participants in the selected body landmarks.
- Conditions
- Upper Extremity, Child, Range of Motion, Articular
- Trial name
- NCT06400667
- Testing
- Upper limb Kinematic Assessment with Optoelectronic system
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Cerebral Palsy, Gait Disorders, Neurologic
Evaluation of Outcomes of Robotics Rehabilitation in Cerebral Palsy
The use of robotic devices in rehabilitation programs can improve walking patterns by reorganizing joint kinematics. This study aims to quantify the effects of a rehabilitation program supported by the Lokomat (Hocoma) robotic…
- Trial name
- LK (NCT06594653)
- Testing
- pre treatment assesment, post treatment assessment
- Where
- Italy
- Volunteers
- 59 people
- Sponsor
- IRCCS Eugenio Medea
Children and Adolescents With Neuromotor Impairment
A Story for Pepper & Nao
The aim of the present study is to improve cognitive processes that are frequently impaired in children characterised by neuromotor impairment, such as the skills of visual-perceptual analysis and selective attention, working…
- Trial name
- LbyT (NCT06797050)
- Testing
- Training in reordering figurative stories with a social robot through the Learning by Teaching approach
- Where
- 3 sites in Italy
- Volunteers
- 80 people
- Sponsor
- IRCCS Fondazione Stella Maris
Congenital and Acquired Neuromotor Disorders, Developmental Coordination Disorder (DCD)
Pediatric Upper-Limb Rehabilitation With PhiCube, a Modular Bilateral End-Effector Device
The present investigation is configured as a multicenter clinical study in a within-group pilot phase. This study aims to investigate primarily the feasibility of use and effectiveness of a treatment for upper limb function in…
- Trial name
- NCT07092436
- Testing
- Robotic bilateral upper limb rehabilitation training
- Where
- 6 sites in Italy
- Volunteers
- 54 people
- Sponsor
- Istituto di Sistemi e Tecnologie Industriali Intelligenti per il Manifatturiero Avanzato
Hereditary Spastic Paraplegia
STOP-HSP.Net: a Registry for Hereditary Spastic Paraplegia as an Integration Tool for Future Therapeutic Strategies
Our goal is to create a solid and harmonious disease registry of patient affected by hereditary spastic paraplegia (HSP) that facilitates the collection and management of patients' data over time encouraging the research and the…
- Trial name
- NCT06572046
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- IRCCS Fondazione Stella Maris
Autism Spectrum Disorder
Sleep Disturbance in Subjects With Autism Spectrum Disorders (ASD) in Preschool Age (18-60 Months)
An observational study is one that aims to collect data from routine clinical practice, without altering a patient's standard diagnostic and therapeutic pathway (no additional instrumental or laboratory tests beyond those…
- Trial name
- NCT07470138
- Testing
- follow up
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Eugenio Medea
Adverse Childhood Experiences, Developmental Risk
Growing Up in Multifactorial Risk Conditions
The perinatal period brings significant physiological and emotional changes in mothers, linked to pregnancy, childbirth, and caring for a newborn.
- Conditions
- Adverse Childhood Experiences, Developmental Risk, Psychomotor Development Disorders, Neurodevelopmental Disorders
- Trial name
- CORE (NCT07477899)
- Testing
- Home visiting programme
- Where
- Italy
- Volunteers
- 352 people
- Sponsor
- IRCCS Eugenio Medea