Clinical trials: Abdominal Surgery by Laparotomy
Postoperative Pain, Midline Laparotomy
Analgesic Outcomes of Ultrasound-Guided QLB vs TAP Block in Midline Laparotomy
This randomized controlled trial compares the analgesic efficacy of ultrasound-guided bilateral lateral quadratus lumborum block (QLB, QL1) versus ultrasound-guided bilateral transversus abdominis plane (TAP) block in adults…
- Conditions
- Postoperative Pain, Midline Laparotomy, Abdominal Surgery
- Trial name
- NCT07796828
- Testing
- Ultrasound-Guided Lateral Quadratus Lumborum Block (QL1), Ultrasound-Guided Transversus Abdominis Plane Block, Bupivacaine 0.25%
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Sheikh Zayed Medical College
Incisional Hernia After Midline Laparotomy, Emergency Abdominal Surgery
Prophylactic Mesh Reinforcement Versus Primary Closure After Emergency Midline Laparotomy (PREEMPT)
The PREEMPT trial is a multicenter randomized controlled trial comparing prophylactic onlay biosynthetic mesh reinforcement with primary suture closure in adult patients undergoing emergency midline laparotomy.
- Trial name
- PREEMPT (NCT07753551)
- Testing
- Prophylactic Biosynthetic Mesh Placement, Direct suture
- Where
- Italy
- Volunteers
- 189 people
- Sponsor
- University of Rome Tor Vergata
Laparoscopy, Abdominal Surgery by Laparotomy
Deep Rectus Sheath (DRS) Block in Abdominal Surgery
The goal of this observational study is to learn about the effectiveness of the Deep Rectus Sheath (Preperitoneal) block in patients undergoing abdominal surgery.
- Trial name
- DRS block (NCT07586462)
- Testing
- Other blocks
- Where
- 2 sites in Italy
- Volunteers
- 60 people
- Sponsor
- San Giovanni di Dio Hospital
Laparotomy Closure After Abdominal Surgery, Suture Materials
Comparison of Vicryl Versus Prolene for Midline Rectus Sheath Closure After Elective Laparotomy
This randomized controlled trial compared two commonly used suture materials, Prolene and Vicryl, for closing the midline rectus sheath after elective laparotomy.
- Conditions
- Laparotomy Closure After Abdominal Surgery, Suture Materials, Complications Wounds
- Trial name
- NCT07451990
- Testing
- Vicryl (Polyglactin 910) Suture, Prolene (Polypropylene) Suture
- Where
- Pakistan
- Volunteers
- 152 people
- Sponsor
- Hayatabad Medical Complex
Laparotomy, Laparotomy Surgery
Saudi Emergency Laparotomy Audit
The Saudi Emergency Laparotomy Audit (SELA) is a national, multicenter observational clinical audit designed to evaluate outcomes and quality of care for patients undergoing emergency laparotomy in Saudi Arabia.
- Conditions
- Laparotomy, Laparotomy Surgery, Emergency Treatment, Abdominal Diseases
- Trial name
- SELA (NCT07429929)
- Testing
- Emergency Laparotomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Postoperative Pain, Abdominal Surgery by Laparotomy
Rectus Sheath Block as an Adjunct to General Anesthesia for Midline Laparotomy Pain
This study evaluates whether adding an ultrasound-guided rectus sheath block (RSB) to general anesthesia can improve pain control after midline laparotomy.
- Trial name
- RSB-MIDLINE (NCT07393763)
- Testing
- Ultrasound-guided rectus sheath block
- Where
- Indonesia
- Volunteers
- 46 people
- Sponsor
- Udayana University
Laparotomy Closure After Abdominal Surgery, Wound Infection, Surgical
Effect of Continuous Versus Interrupted Suturing on Wound Dehiscence and Infection After Abdominal Surgery
The goal of this clinical trial is to learn whether the type of suturing technique used to close the abdomen after exploratory laparotomy affects the rate of wound complications.
- Conditions
- Laparotomy Closure After Abdominal Surgery, Wound Infection, Surgical, Dehiscence of Laparotomy Wound, Suture, Interrupted
- Trial name
- NCT07241507
- Testing
- Continuous suturing, Interrupted suturing
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Allama Iqbal Teaching Hospital
Abdominal Surgery by Laparotomy, Thoracic Epidural Analgesia
Evaluation of Plasma Concentrations of Intravenous Lidocaine and Epidural Ropivacaine When Used in Combination in Major Abdominal Surgery
Thoracic epidural analgesia (TEA) is the gold standard analgesia of the laparotomy in major abdominal surgery and can be associated with intravenous lidocaine or subtituted by intravenous lidocaine when TEA is contraindicated and…
- Conditions
- Abdominal Surgery by Laparotomy, Thoracic Epidural Analgesia, Analgesia, Lidocaine Adverse Reaction
- Trial name
- LARA (NCT05368753)
- Testing
- Blood sample, Lidocain, ropivacaine
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Abdominal Surgery by Laparotomy
Hot Compress Application in Open Abdominal Surgery
This study aims to evaluate the effect of hot compress application to the intestines during abdominal surgery on postoperative nausea-vomiting and bowel function.
- Trial name
- HotCompress (NCT06888154)
- Testing
- compress application with heated saline
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Laparotomy Closure After Abdominal Surgery
Comparing Delayed vs Primary Wound Closure After Emergency Laparotomy: Impact on Infection, Healing, and Hospital Stay
The purpose of this study is to find out which type of wound closure after emergency abdominal surgery leads to fewer wound infections and better recovery: closing the wound immediately after surgery (called primary closure) or…
- Trial name
- NCT07142395
- Testing
- Immediate skin closure, Delayed primary closure
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- Bkahtawar Amin Medical and Dental College Multan
Abdominal Trauma, Damage Control Surgery
Clinical Outcomes of Non-Indicated Staged Laparotomies in Abdominal Trauma
The goal of this observational study is to understand how often staged operations are performed in abdominal trauma patients without meeting standard clinical criteria, and to explore related clinical characteristics and…
- Conditions
- Abdominal Trauma, Damage Control Surgery, Laparotomy
- Trial name
- NCT07110350
- Testing
- Laparotomy refers to a definitive single-stage exploratory abdominal surgery. Damage Control Surgery refers to a staged surgical approach including initial abbreviated laparotomy followed by planned.
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- Far Eastern Memorial Hospital
Laparotomy Closure After Abdominal Surgery
Duramesh™ vs Polydioxanone Suture for Laparotomy Closure
This study is intended to demonstrate the non-inferiority of a Duramesh closure as compared to a polydioxanone closure for early surgical site events (SSE) (< 1 month), and Duramesh superiority to polydioxanone for the…
- Trial name
- MOMENTUM RCT (NCT05804136)
- Testing
- Duramesh, Polydioxanone suture
- Where
- Belgium
- Volunteers
- 230 people
- Sponsor
- University Hospital, Ghent
Laparotomy, Dehiscence Wound
Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT
This randomized control trial aims to compare the efficacy of triclosan-coated barbed suture (TCB) versus conventional non-barbed polydioxanone (PDS) suture in the closure of the abdominal fascia after emergency exploratory…
- Conditions
- Laparotomy, Dehiscence Wound, Surgical Site Infections, Trauma Abdomen
- Trial name
- NCT06043414
- Testing
- triclosan-coated barbed suture, triclosan-coated non-barbed suture, Non-coated non-barbed suture
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Southern California
Gynecologic Malignancy, Abdominal Surgery by Laparotomy
Mindful Movement and Breathing to Improve Outcomes of Gynecologic Surgery
The purpose of this clinical trial is to understand if women undergoing surgery for a suspected gynecologic malignancy are interested in participating in a Mindful Movement and Breathing program and what the effects of this…
- Conditions
- Gynecologic Malignancy, Abdominal Surgery by Laparotomy, Pain, Psychological Distress
- Trial name
- NCT01593657
- Testing
- Mindful Movement and Breathing program, Questionnaire administration, The Observer Mobility Scale
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences