Clinical trials: Absorption; Iron
Enrichment of Blood
Iron Absorption From Biofortified Beans With Different Levels of Phytic Acid
Iron deficiency and iron deficiency anemia are among the major health problems in the developing world. Women of childbearing age as well as children are the most vulnerable population groups.
- Trial name
- NCT01521273
- Testing
- Bean varieties
- Where
- Rwanda
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Nutritional Deficiency
Bioavailability of Zinc and Iron From a Whey-based Protein Supplement Consumed With a Habitual Plant-based Diet
Bioavailability of iron and zinc from habitual plant-based diets consumed by young children in Mexico is low due to the high phytate content.
- Trial name
- NCT02208622
- Testing
- Study 1: Whey Supplement Day 1, Study 1: Whey Supplement Day 2, Study 2: Whey Supplement
- Where
- 2 sites in United States, Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Iron-deficiency
Iron Absorption From Fortified Extruded Rice Using Different Extruding Temperatures.
Food fortification is regarded as a safe and cost-effective approach to counteract and prevent iron deficiency. Rice is a staple food for millions of people living in regions where iron-deficiency anaemia is a significant public…
- Trial name
- NCT03703726
- Testing
- Reference meal, Test meal A, Test meal B
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron-deficiency
Effect of Polyphenols on Absorption of Iron From Sodium Iron Chlorophyllin
Polyphenols present in tea are known to inhibit the absorption of non heme iron. The inhibiting effect of tea on non-heme iron absorption is attributed to the flavonoids present in tea.
- Trial name
- polySIC (NCT04849832)
- Testing
- SIC, SIC + tea, FeSO4
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency, Anemia
The Efficacy of a Local Vitamin-C Rich Fruit (Guava) in Improving Iron Absorption From Mungbean Based Meals and Its Effect on Iron Status of Rural Indian Children (6-10 Years)
Iron deficiency is estimated to affect about one fifth of the world's population, and women and children are among the most severely affected.
- Trial name
- MUGUST_2 (NCT01191463)
- Testing
- Mung Bean Meal, Guava
- Where
- India
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Iron Deficiency
Absorption of Heme and Non-Heme Iron in Pregnant and Non-pregnant Women and Mechanisms of Fetal Iron Transfer
The three specific aims of this study are 1) to assess the impact of iron status on relative differences in absorption of heme and non-heme iron among pregnant women and non-pregnant women, 2) to assess the magnitude and the…
- Trial name
- NCT01019096
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Cornell University
Nonheme Iron Absorption
Iron Bioavailability From MyPyramid Menus
This study will measure nonheme iron absorption from each of the 7 daily MyPyramid menus. Such measurements will confirm whether modifications are needed to meet dietary iron recommendations and will provide data useful for…
- Trial name
- NCT00754234
- Testing
- My Pyramid menu days 1, 2, 3, 4, 5, 6 or 7
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Iron-deficiency, Absorption; Iron
Iron Absorption From Iron-enriched Aspergillus Oryzae
Ferrous sulfate is rapidly absorbed and the bolus of iron enters blood rather quickly possibly leading to higher concentrations of non-transferrin bound iron which induces oxidative stress.
- Conditions
- Iron-deficiency, Absorption; Iron, Anemia, Iron Deficiency, Bioavailability
- Trial name
- BIEFS (NCT03156712)
- Testing
- Ferrous sulfate
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Zinc Absorption, Iron Absorption
Zinc and Iron Absorption From Common Beans in Young Adult Women
Fifteen female study participants will be enrolled in a randomized crossover study to measure fractional and total zinc and iron absorption from four common bean (Phaseolus vulgaris) varieties with varying phytate and…
- Trial name
- NCT06327529
- Testing
- SER 118, LMP 1001, LPA 586
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Infant, Dietary Supplements
Iron Absorption From Infant Formula and Iron Drops in Infants (MJAU-studien)
Iron deficiency (ID) affects up to 25% of Swedish infants and severe ID is associated with cognitive and behavioral problems. To avoid this, iron supplements or iron-fortified infant foods are recommended for infants.
- Conditions
- Infant, Dietary Supplements, Food, Fortified
- Trial name
- MJAU (NCT01216709)
- Testing
- ferrous sulfate, iron-fortified infant formula (12.4 mg iron/L), iron-fortified infant formula (2.3 mg iron/L)
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Umeå University
Iron Deficiency
Effect of Coca-Cola on Iron Absorption
The aim of this project is to measure the effect of Coca-Cola and Diet Coke, relative to mineral water, on non-haem iron absorption.
- Trial name
- NCT00474500
- Testing
- Coca, Cola, Diet Coke
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Iron Absorption
Iron Long-Term Labelling Study Malawi
Conventional indirect indicators of iron status, using serum and red blood cell biomarkers, are confounded by inflammation from common infections in sub-Saharan Africa, a region with a high prevalence of iron deficiency, making…
- Trial name
- NCT02977806
- Where
- Malawi
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Prof. Michael B. Zimmermann
Iron Deficiency
Iron Absorption From GDS Capsules II
Slow release iron capsules containing ferrous sulfate have been designed based on the gastric delivery system. Iron absorption from those capsules administered with and without meals will be measured using stable iron isotopes.
- Trial name
- NCT01985386
- Testing
- GDS capsule with meal, Ferrous sulfate with meal
- Where
- Switzerland
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Undernutrition, Healthy
Iron Absorption From Lipid-Based Nutrient Supplements
The overall objective of this study is to determine dietary iron absorption from lipid-based nutrient supplements (LNS) in apparently healthy and undernourished children.
- Trial name
- NCT06870201
- Testing
- Lipid-Based Nutrient Supplement
- Where
- Kenya
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Iron Deficiency
Malaria and the Safety of Iron Supplements and Iron Fortification
The primary study hypothesis of the investigators is that administration of an iron supplement between meals at a dose like that used in the Pemba trial (~1 mg Fe/kg) during P.
- Trial name
- MIA (NCT01156896)
- Testing
- Ferrous sulfate
- Where
- Thailand
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Columbia University
Obesity & Overweight, Normal Weight Adults
Long-term Iron Absorption and Loss in Women
Obese people typically have chronic low-grade inflammation. Based on short-term studies, this inflammation could affect the absorption, utilization, storage, and mobilization of iron, and individuals with inflammation might…
- Trial name
- NCT07855939
- Where
- Thailand
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Blood Iron Isotope Enrichment
Impact of Bean Polyphenols and Phytic Acid on Iron Absorption
Recently isolated low PA varieties (lpa) in wheat, rice, maize, barley and beans might have the potential to alleviate iron bioavailability problems associated with PA.
- Trial name
- NCT01472484
- Testing
- 586/8x87 white, 586/8x87 brown, BAT 881
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency, Anaemia
Iron & Alginate Study
Iron deficiency anaemia affects around two billion people worldwide. Food fortification with iron is a realistic way to combat this problem.
- Trial name
- NCT01528644
- Testing
- alginate beads containing ferrous gluconate, ferrous gluconate in a capsule, ferrous gluconate in a capsule in presence of calcium
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
Healthy Volunteer, Mothers
Serum Ferritin Concentration in Kenyan Women and Their Preschool Children at Which the Body Begins to Upregulate Iron Absorption From the Diet
Using standardized methods, the investigators will perform stable iron isotope absorption studies in young Kenyan women and their preschool children (2-5y of age) with varying iron status to measure iron absorption from maize…
- Conditions
- Healthy Volunteer, Mothers, Preschool Children
- Trial name
- NCT06655909
- Testing
- consumption of maize porridge containing stable iron isotope
- Where
- Kenya
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Isabelle Herter-Aeberli
Iron Deficiency (Without Anemia)
Effect of Chitin and Ascorbic Acid on Dietary Insect Iron Absorption
Iron is involved in many vital metabolic processes such as oxygen transport, electron transport in cells, DNA synthesis and repair, and muscle metabolism.
- Trial name
- INSECTE (NCT06822062)
- Testing
- Meal A, Meal B, Meal C
- Where
- Switzerland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Swiss Distance University of Applied Sciences