Clinical trials: Accidental Injuries
Trauma, Blunt Injury
Plasma Cytochrome c as Biomarker of Traumatic Injury and Predictor of Outcome
Cytochrome c is a mitochondrial protein that plays a key role in energy metabolism. When mitochondria are injured, cytochrome c may leave mitochondria and reach the bloodstream.
- Conditions
- Trauma, Blunt Injury, Blunt Trauma, Accident
- Trial name
- NCT02440373
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Wake Forest University Health Sciences
Trauma Injury
Captain Sonar Impact on Trauma Patient Management
Trauma patient care requires collaboration and interaction with close relationship between many stakeholders from different professions (senior doctor, intern, nurse, nurse helpers, surgeons, etc).
- Trial name
- CAST2 (NCT05628519)
- Testing
- Captain Sonar Exposition, Monopoly Exposition
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Claude Bernard University
Accidental Falls, Fractures
Clinical Evaluation of a Wireless Monitoring Device to Reduce Falls in the Elderly and Others at High Risk of Falling
Falls are a public health problem of significant social and economic significance. No primary intervention devices have been shown to be effective in reducing falls and associated injuries.
- Conditions
- Accidental Falls, Fractures, Injuries
- Trial name
- NCT00249743
- Testing
- FallSaver (formerly called NOCwatch)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NOCwatch International
Non-compressible Torso Hemorrhage, Trauma Injury
Resuscitative Endovascular Balloon Occlusion of the Aorta in Haemorrhagic Shock
Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a procedure that has the goal to stabilize trauma patients with non-compressible torso hemorrhage by temporarily occluding the aorta with a ballon catheter to…
- Trial name
- NCT05941572
- Where
- Austria
- Sponsor
- Medical University of Graz
Trauma Injury, Bleeding
Micro Plug Set - Post Market Clinical Follow-up (PMCF) Plan
This is an observational, post market clinical follow-up (PMCF) intended to evaluate the residual risks of the Micro Plug Set which is intended for use during arterial embolization of the peripheral vasculature.
- Trial name
- NCT04218292
- Testing
- Micro Plug Set
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- KA Medical, LLC
Accidental Fall, Fall
Remote Monitoring and Analysis of Gait and Falls Within an Elderly Population
The investigators aim to do this initial pilot study as an observational prospective cohort study, evaluating elderly patients who have capacity in National Health Service (NHS) rehabilitation and community hospitals.
- Conditions
- Accidental Fall, Fall, Fall Injury, Hip Fractures
- Trial name
- 4279 (NCT03680014)
- Testing
- CUSH
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CUSH Health Ltd.
Emergencies, Trauma Injury
Pre-Hospital Zone 1 Partial Resuscitative Endovascular Balloon Occlusion of the Aorta for Injured Patients With Exsanguinating Sub-diaphragmatic Haemorrhage
It is unknown whether this evolved strategy (Pre-Hospital Zone I P-REBOA) is feasible and with an acceptable safety profile. This study will address this question, therefore informing the design of a prospective multicentre…
- Conditions
- Emergencies, Trauma Injury, Trauma, Multiple
- Trial name
- P-PRO (NCT04145271)
- Testing
- Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA)
- Where
- 4 sites in United Kingdom
- Volunteers
- 10 people
- Sponsor
- Barts & The London NHS Trust
Multiple Trauma
Importance of Forces and Safety Features in Car Crash Multitrauma
The pupose of the study is a prospective evaluation of external and internal factors/causes of importance for the trauma and final outcome experienced by persons inside motor vehicles in serious car accidents.
- Trial name
- NCT00204204
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- University of Oslo
Trauma Injury, Airway Control
LITES Task Order 0005 Prehospital Airway Control Trial (PACT)
The Prehospital Airway Control Trial (PACT) is a proposed 5 year, open label, multi-center, stepped-wedge randomized trial comparing airway management strategies of prehospital trauma patients.
- Trial name
- PACT (NCT04100564)
- Testing
- Supraglottic airway device, Standard airway management
- Where
- 14 sites in United States
- Volunteers
- 2,010 people
- Sponsor
- Jason Sperry
Trauma Injury, War Injury
Surgery in Context of Terrorist Attack : a Survey of French Surgeons
The aim of the study is to assess the surgical knowledge of French Surgeons in cas of Terrorist Attack.
- Conditions
- Trauma Injury, War Injury, Surgical Procedure, Unspecified
- Trial name
- NCT04327895
- Testing
- evaluation of the need for training
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Trauma Injury
How Many Patients Suffering Major Trauma Would be Eligible for a Pre-hospital Transfusion
The aim of the study is to measure the number of patients being cared for by a medical team for major trauma who could benefit from a transfusion labile blood products and thus provide a scientific argument in favour of supplying…
- Trial name
- TRAP (NCT06494293)
- Testing
- Data Collection
- Where
- 4 sites in France
- Volunteers
- 200 people
- Sponsor
- Hôpital NOVO
Fall, Fall Injury
Testing the SNOWDROP Intervention: Using a Clinical Decision Support System and Patient Portal for Falls Prevention Among Older Patients in Primary Care
Falls are a leading cause of injuries among older patients. Medication use is a major risk factor for falls. Because we lack tools to assess individualized risks, general practitioners (GPs) struggle with fall-related medication…
- Conditions
- Fall, Fall Injury, Fall Patients, Accidental Fall
- Trial name
- SNOWDROP (NCT05611008)
- Testing
- CDSS, Patient Portal
- Where
- Netherlands
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Amsterdam
Aircraft Accident
An Analysis of Air-Crash Injury Patterns Presenting at a Level 1 Trauma Unit in Johannesburg, a Retrospective Cohort Study.
Aviation related deaths are often fatal, with most patients dying at the scene; however, with increased safety and improvement in medical management, patients are surviving aviation accidents.
- Trial name
- NCT04728373
- Testing
- surgery
- Volunteers
- 56 people
- Sponsor
- Sefako Makgatho Health Sciences University
Trauma Injury, Thromboembolism
Antithrombin to Improve Thromboprophylaxis and Reduce the Incidence of Trauma-Related Venous Thromboembolism
The purpose of this study is to determine if additional interventions will assist with decreasing the risk and/or severity of thromboembolism (clotting complications) in patients who have experienced a major traumatic event.
- Conditions
- Trauma Injury, Thromboembolism, Venous Thromboembolism
- Trial name
- TRAIT (NCT05794165)
- Testing
- Thrombate infusion
- Where
- 5 sites in United States
- Volunteers
- 314 people
- Sponsor
- Bryan Cotton
Trauma Injury, Maxilla Fracture
Prospective Study to Evaluate the Performance and the Safety of Global D's Implants of Craniomaxillofacial Surgery (CMF) Ranges Indicated for Trauma Surgery
This study is set up within the framework of the European Union regulation 2017/745 on medical devices. Its objective is to confirm the performance and safety of the Global D implants (ORTRAUTEK® and MINITEK/MICROTEK®) used for…
- Conditions
- Trauma Injury, Maxilla Fracture, Maxillofacial Trauma
- Trial name
- NCT05742932
- Testing
- Trauma surgery using Global D's implants.
- Where
- 2 sites in France
- Volunteers
- 99 people
- Sponsor
- Global D
Traumatic and/or Non-traumatic Brain Injury
Assessing Special Features of Impaired Gait After Acquired Brain Injury With an Instrumented Treadmill
Hemiparetic gait following acquired brain injury (ABI) is grossly characterized by decreased speed of walking, increased stance time on the unaffected side, and decreased stance time on the affected side.These abnormalities are…
- Trial name
- NCT01413321
- Where
- Israel
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Burns, Smoke Inhalation Injury
Helping Children's Centres to Enhance Home Safety
Many children have accidents, some are very serious and they are a major cause of death in children aged 1-4 years. Many accidents are preventable This study aims to find out the best way to help Children's Centres to provide…
- Trial name
- NCT01452191
- Testing
- Injury Prevention Briefing Plus facilitation, Injury Prevention Briefing
- Where
- 4 sites in United Kingdom
- Volunteers
- 1,112 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Endosseous Dental Implant Failure, Accident Caused by Broken Ceramic
Monolithic Zirconia Full-Mouth Implant Supported Rehabilitation Behavior
In patients rehabilitated with a full-arch (maxillary and/or mandibular) implant-supported fixed prosthesis, do three CAD/CAM zirconia framework designs - porcelain-veneered zirconia (PVZ), monolithic zirconia with buccal veneer…
- Trial name
- NCT01974362
- Testing
- Dental Implant, Monolithic Zirconia (MZ), Zirconia-Feldspathic (PVZ)
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Alcohol Drinking, Alcohol Use Disorder
Effect of Theta Burst Stimulation on Alcohol Cue Reactivity
Alcohol Use Disorder (AUD) is prevalent, devastating, and difficult to treat. The intransigence of AUD is readily apparent in the Trauma Unit of Wake Forest University Baptist Hospital, wherein 23% of trauma related admissions…
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Trauma Injury, Alcohol Dependence
- Trial name
- NCT04223154
- Testing
- Real iTBS to the dlPFC
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Wake Forest University Health Sciences
Injury
Prevention of Posttraumatic Stress Symptoms and Behavioral Problems in Children After Road Traffic Accidents: a Randomized Controlled Trial
The purpose of this study is to study the effectiveness of an early psychological intervention 7-10 days after a road traffic accident on posttraumatic stress and behavior of children and adolescents
- Trial name
- NCT00296842
- Testing
- Early psychological intervention
- Where
- Switzerland
- Volunteers
- 99 people
- Sponsor
- University Children's Hospital, Zurich