Clinical trials: Acute Physical Exercise
Healthy
Metabolic Adaptations to Chronic and Acute Exercise in Overweight Adults (ATX-Study)
The primary purpose of this study is to examine the effects of chronic exercise training and an acute session of exercise on key risk factors associated with Metabolic Syndrome (e.g., glucose tolerance, blood lipid profile, and…
- Trial name
- ATX (NCT02701751)
- Testing
- Exercise session
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Athletes
The Acute Effects of Combined Caffeine and Sodium Bicarbonate Consumption on Isometric Mid-thigh Pull
The aim of this study was to investigate the effects of isolated and combined caffeine and sodium bicarbonate consumption on acute isometric mid-thigh pull (IMTP) strength, and verify whether they are cumulative, neutral or…
- Trial name
- NCT05883046
- Testing
- Performance-Enhancing Substances, Baseline (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Bozok University
Healthy Young Men, Healthy Young Women
Characterization of the Plasma Metallomic Profile to Acute Exercise in Healthy Men and Women (METALEXO)
Among the various trace elements playing a key role in physical performance, iron is probably one of the most studied in the last 30 years.
- Trial name
- METALEXO (NCT05718752)
- Testing
- Maximal incremental exercise test, 30-min submaximal exercise test
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Post-COVID Syndrome
Exercise Intolerance in Post-COVID Patients
The post-COVID syndrome poses an unprecedented challenge to modern society, affecting millions of people worldwide. Persistent fatigue and exercise intolerance are among the most common complaints of these subjects.
- Trial name
- EXILE (NCT05445830)
- Testing
- High-Intensity-Interval-Exercise, Moderate-Intensity-Continuous-Exercise, Strength training
- Where
- Sweden
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Insomnia, Healthy Adult
The Effect of Different rTMS Interventions on Acute Experimental Muscular Pain in Individuals Comorbid With Insomnia
Insomnia exacerbates pain sensitivity and impairs physiological recovery from acute musculoskeletal pain. Repetitive transcranial magnetic stimulation (rTMS) has emerged as a promising non-invasive neuromodulation intervention to…
- Conditions
- Insomnia, Healthy Adult, Exercise Induced Muscle Damage, Pain Sensitivity
- Trial name
- NCT07827677
- Testing
- Repetitive transcranial magnetic stimulation (rTMS) on L M1, Repetitive transcranial magnetic stimulation (rTMS) on R DLPFC
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Proteomics, Exercise
Dynamic Proteomics and Integrated Rates of Muscle Protein Synthesis During an Acute Period of Loading and Unloading
Skeletal muscle plays several different roles in the promotion and maintenance of health and well-being. The loss of muscle mass that occurs with aging, chronic muscle wasting diseases, and physical inactivity puts people at an…
- Conditions
- Proteomics, Exercise, Atrophy, Disuse, Hypertrophy
- Trial name
- HYPAT (NCT04514744)
- Testing
- Knee bracing, Unilateral Resistance Exercise Training
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- McMaster University
Adolescent Athletic Performance, Flexibility
Effects of Myofascial Release, Dynamic and Static Stretching in Adolescent Karate Athletes
This randomized single-blind crossover trial investigated the acute effects of three different exercise modalities, namely self-myofascial release with a foam roller, dynamic stretching, and static stretching, on posture…
- Conditions
- Adolescent Athletic Performance, Flexibility, Stretching Exercises, Sports Physical Therapy
- Trial name
- NCT07573267
- Testing
- Static Stretching, Dynamic Stretching, Self Myofascial Release
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Istinye University
Alteration of Cognitive Function
Exercise and Cognition Trials
The purpose of this study is to determine whether an acute bout of exercise may temporarily enhance cognitive function (such as memory or attention span) by measuring behavioral performance on cognitive tests, as well as…
- Trial name
- EXACT (NCT02958735)
- Testing
- Exercise Challenge
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Biological Maturation
Biological Maturation and Plyometric Exercise
Plyometric training comprises one of the most widely used training methods in both individual and team sports, and is widely used by coaches as one of the main training in both adults, and children.
- Trial name
- BiMaPlEx (NCT05442593)
- Testing
- Plyometric training
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Ketosis, Muscle Protein Synthesis
Exogenous Ketosis and Muscle Protein Synthesis During Exercise Recovery
An acute bout of resistance exercise stimulates muscle protein synthesis (MPS) rates for up to 24-48 hours, supporting muscle growth and repair.
- Conditions
- Ketosis, Muscle Protein Synthesis, Dietary Proteins, Resistance Exercise
- Trial name
- NCT06769100
- Testing
- Ketone Monoester (KET), Ketone Monoester + Whey Protein (KET+PRO), Whey Protein (PRO)
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- McGill University
Diabetes Prevention, Obesity Prevention
PERFECT Project - Part 1 - Study 2
The objectives are to test the acute effects of different cereals containing pulse ingredients on: 1) post-prandial blood glucose, insulin and appetite for two hours, and 2) food intake two hours following consumption of pulse…
- Trial name
- NCT02366572
- Testing
- Control, Pea protein, Pea starch
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Contracture
Effect of a Protein-enriched Drink on Muscle Function
There is no conclusive evidence about the effect of intake of protein-enriched drink after and acute high intensity exercise bout on muscle function and damage.
- Trial name
- SPORTEUS (NCT02385357)
- Testing
- Protein-enriched drink
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Puleva Biotech
Osteoporosis, Aging
Exercise Mode and Acute Bone Resorption
Endurance exercise is often recommended to improve cardiometabolic health and maintain bone health throughout life and to prevent osteoporotic fracture.
- Trial name
- NCT04815824
- Testing
- Exercise Mode
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Oxygen Utilization, Oxygen Kinetics
Mushroom Blend on Oxygen Kinetics
Purpose: To determine the acute effects of a mushroom blend vs. placebo on oxygen kinetics, aerobic power and time to fatigue in healthy adults.
- Trial name
- NCT02075892
- Testing
- Mushroom Blend
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Cognition, Sodium Bicarbonate
Exercise-Induced Lactate and Cognitive Function (ExLBC)
A single bout of exercise can rapidly improve cognitive functions including memory, attention, and executive functions, which help us navigate through everyday life.
- Conditions
- Cognition, Sodium Bicarbonate, Lactate, Exercise
- Trial name
- NCT06817681
- Testing
- Sodium Bicarbonate (NaHCO3)
- Where
- 2 sites in Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- McMaster University
Post-exercise Period, Ketosis
Acute Effects of Ketone Monoester Co-ingestion With Dietary Protein on Whole-body Phenylalanine Oxidation, Phenylalanine Retention, and Myofibrillar Protein Breakdown Following Resistance Exercise in Young Males.
The goal of this trial is to determine if ketone monoester supplementation in conjunction with protein supplementation in the post exercise period can augment whole-body protein metabolism following resistance exercise in young…
- Conditions
- Post-exercise Period, Ketosis, Resistance Exercise, Dietary Protein
- Trial name
- (KET-YOUNG-M) (NCT07884539)
- Testing
- Ketone Monoester + Dietary Protein (KET+PRO), Dietary Protein (PRO), Resistance Exercise
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- McGill University
Adipose Tissue Gene Expression
The Influence of Different Dietary Status on the Acute Responses to Exercise
The purpose of this study is to investigate whether dietary conditions (fed versus fasted) affects the acute responses to exercise.
- Trial name
- NCT02870075
- Testing
- Fed exercise, Fasted exercise
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Bath
Obesity, Obesity; Endocrine
Acute and Chronic Metabolic Flexibility in Individuals Living With Obesity: The i-FLEX Study
Regular exercise is a cornerstone in the prevention and the management of cardio-metabolic risk factors. Some of the beneficial effect of exercise training occurs through metabolic flexibility' enhancement.
- Conditions
- Obesity, Obesity; Endocrine, Insulin Sensitivity, Exercise
- Trial name
- i-FLEX (NCT03527446)
- Testing
- Sprint Interval Training
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of New Brunswick
Healthy Adults, Adults With Stress-related Symptoms
Exercise Intensity on Brain & Mental Health in Stress
This study aims to examine the role of exercise intensity in the acute effects of a single bout of aerobic exercise on neurotrophic factors, biomarkers of stress and inflammation, working memory task-related changes in prefrontal…
- Trial name
- ExStress (NCT06245538)
- Testing
- Seated rest, Exercise at moderate intensity, Exercise at vigorous intensity
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Swedish School of Sport and Health Sciences
Blood Flow Restriction Exercise
PAPE Effect With Blood Flow Restriction and Push-Up Exercise (Post-Activation Performance Enhancement)
This study aims to compare the acute effects of push-up exercises performed under different blood flow restriction (BFR) conditions on upper extremity explosive strength performance, measured via the seated unilateral medicine…
- Trial name
- PAPE (NCT07015515)
- Testing
- Control group, Blood flow restriction exercise group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul University