Clinical trials: Advanced Age
Sarcopenia, Muscle Weakness
Foot Core Exercise Program on Balance Control and Walking in Aged Sarcopenia
In modern society with an increasing aging population, recent literature has defined sarcopenia as a significant reduced mass and function of skeletal muscle with physical limitations due to aging.
- Conditions
- Sarcopenia, Muscle Weakness, Walking, Difficulty, Balance Control
- Trial name
- NCT05750888
- Testing
- integrated exercise therapy with 3D printing exerciser for training intrinsic foot muscles, regular exercises for the elderly
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Physical Function, Vitamin D Insufficiency
Vitamin D Supplementation and Physical Function in Older Adults
A growing body of evidence suggests that vitamin D status is important in biologic processes involved in the maintenance of physical function.
- Trial name
- NCT01179503
- Testing
- calcium, Vitamin D plus calcium
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Older Adults
Effects of Ballet Training on Postural Stability in Older Adults
The purpose of this study is to examine the changes in postural stability in older adults following exposure to a beginning ballet dance technique course.
- Trial name
- NCT03691259
- Testing
- Ballet Classes
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Skidmore College
Age-Related Memory Disorders
Effectiveness of a Cognitive Training Program (UMAM Method) in Elderly People Without Dementia
The study is oriented to analyze the effectiveness of a cognitive training method (UMAM) on cognitive functions, subjective memory and mood state in elderly people without dementia.
- Trial name
- NCT04245579
- Testing
- Multifactorial Memory Training Program (UMAM method)
- Where
- Spain
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Madrid Salud
Postural Balance
Feasibility of a Tablet-based Fall Prevention Program for Older Adults
There are many exercise approaches that have demonstrated effectiveness in reducing falls and fall risk in community-dwelling older adults. The Otago Exercise Program is one such program.
- Trial name
- NCT02949986
- Testing
- Tablet-based Fall Prevention
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- East Tennessee State University
Plyometric Exercise, Elderly
The Effect of Plyometric Training on the Balance Ability of the Lower Limbs in the Elderly
For the elderly using plyometric training, there are very few studies on strengthening the explosive power of the lower limbs of the elderly.
- Conditions
- Plyometric Exercise, Elderly, Balance
- Trial name
- NCT06000124
- Testing
- Plyometric exercises, Regulation Exercises Program
- Where
- Taiwan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Fall Prevention, Fall Injury
Safe Landing Strategy in Older Adults
The purposes of this project to examine whether older adults can learn safe landing strategy during a fall. The research hypotheses are three-fold: 1) To determine whether older adults can learn a safe landing strategy to reduce…
- Conditions
- Fall Prevention, Fall Injury, Fall Safety
- Trial name
- NCT03540082
- Testing
- Tuck and Roll Group, Fall Exposure
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Muscle Protein Synthesis, Muscle Atrophy
Exogenous Ketosis During Bed Rest in Older Adults
The goal of this randomized, double-blind, parallel group interventional study is to evaluate the effect of ketone bodies on healthy older adults (65-85 y) during 5 days of bed rest.
- Conditions
- Muscle Protein Synthesis, Muscle Atrophy, Insulin Sensitivity, Mitochondrial Function
- Trial name
- KBR (NCT05679596)
- Testing
- ketone monoester (R)-3-hydroxybutyl (R)-3- hydroxybutyrate
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University
Frailty, Cognitive Decline
Precision Stratification for Frailty and Cognitive Decline
The Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB) trial aim to test the effectiveness of an exercise, cognitive and lifestyle intervention amongst older adults over a 12-weeks…
- Trial name
- NCT07081282
- Testing
- Care4Senior mobile Application, Intensive Aerobic Resistance Training and Brain Health (CIRTAB), Centre-Based Exercise Health Session
- Where
- Singapore
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
FRAILTY
FRED Exergame Including Biofeeback Supervision
A pilot six-week randomised controlled trial was carried out introducing biofeedback with physiological constants as follows: systolic blood pressure, diastolic blood pressure, heart rate and blood oxygen saturation in the…
- Trial name
- NCT03425227
- Testing
- FRED EXERGAME
- Where
- Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Begoña Garcia Zapirain
Influenza
Multi-Year Study of Fluzone High-Dose Influenza Vaccine Compared With Fluzone® Vaccine in Adults Aged 65 Years and Older
The aim of this study is to determine the efficacy of Fluzone High Dose vaccine and that of Fluzone® vaccine in the elderly. Primary objective: To measure the efficacy of the vaccine, defined as the prevention of…
- Trial name
- NCT00976027
- Testing
- Trivalent inactivated influenza vaccine High Dose, Trivalent inactivated influenza vaccine
- Where
- 98 sites in United States, Puerto Rico
- Volunteers
- 9,172 people, healthy volunteers welcome
- Sponsor
- Sanofi
Osteopenia, Osteoporosis
Time-specific Exercise in Circadian Context
The project aims to explore the mechanisms, by which physical activity can support healthy ageing and decrease the negative impact of ageing on the circadian system, musculoskeletal system and immunity.
- Conditions
- Osteopenia, Osteoporosis, Aging
- Trial name
- CAEx (NCT06746649)
- Testing
- Combined training
- Where
- Slovakia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Comenius University
Healthy, Mild Cognitive Impairment
Supporting Episodic Memory With Transcranial Direct Current Stimulation in Healthy Controls and Dementia Patients
Previous studies showed that anodal tDCS applied over the dorsolateral prefrontal cortex (DLPFC) improved episodic memory performance, indicating a possible use as an intervention for patients suffering from memory impairments.
- Conditions
- Healthy, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT03227185
- Testing
- real anodal transcranial direct current stimulation (tDCS)
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Bern
Falling, Community Dwelling Older Adults
Neurophysiological Changes After Perturbation-based Training in Older Adults
This is an assessor-blinded neurophysiological study. Participants will be randomly assigned to a perturbation-based training (PBT) or a walking (control) group.
- Conditions
- Falling, Community Dwelling Older Adults, Postural Stability, Brain Connectivity
- Trial name
- NCT06573658
- Testing
- Perturbation-based balance training (PBT), Walking exercise (control)
- Where
- Hong Kong
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Pneumonia, Urinary Tract Infection
Identification of Admission High Risk Elderly
Objective: The study aim to establish high risk admission model and readmission model for elderly in Taiwan. Method: Investigators compare the clinical, epidemiological, and socioeconomic characteristics of admitted patients…
- Conditions
- Pneumonia, Urinary Tract Infection, Stroke
- Trial name
- NCT01934426
- Where
- Taiwan
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Falls
VISIBLE Study (Visual Intervention Strategy Incorporating Bifocal & Long-distance Eyewear)
The purpose of this study is to determine whether the provision of supplementary plain distance glasses for outdoor use to older users multifocal glasses will reduce falls rates over a 12 month period.
- Trial name
- VISIBLE (NCT00350389)
- Testing
- Outdoor use of plain distance glasses with counselling
- Where
- Australia
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- The University of New South Wales
Old Age; Debility, Satisfaction
TIKeasy TAblet satisfaCtion (TikTac)
In the last ten years, gerontechnology is becoming an increasing topic in geriatric medicine. Nevertheless, there are still few studies assessing the usability of technologies in old patients, especially when they are…
- Trial name
- TikTac (NCT04091152)
- Testing
- usability assessment
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Tooth Extraction, Postoperative Hemorrhage
Post-extraction Bleeding in Older Adults on Uninterrupted Antiplatelet Therapy
This prospective, assessor-blinded, controlled observational study compares bleeding after simple tooth extraction between adults aged 40 years or older who continue their antiplatelet therapy (aspirin, clopidogrel or dual…
- Conditions
- Tooth Extraction, Postoperative Hemorrhage, Platelet Aggregation Inhibitors
- Trial name
- NCT07913035
- Testing
- Antiplatelet therapy (uninterrupted), Simple tooth extraction with stepwise local haemostatic protocol
- Where
- Vietnam
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Acute Pain
Trial Comparing Morphine to Hydromorphone in Elderly Patients With Severe Pain
The purpose of this research study is to determine which opiate pain medication (morphine or hydromorphone (Dilaudid)) is more effective in the treatment of acute pain in patients presenting to the emergency department.
- Trial name
- NCT00305058
- Testing
- Morphine, Hydromorphone
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
eHealth Literacy
Improving eHealth Literacy of Older Adults in Hong Kong
This study is an randomized controlled trial (RCT) study to examine the feasibility and effectiveness of a community-based health promotion education intervention for improving the eHealth literacy of older adults
- Trial name
- NCT06374576
- Testing
- Lecture on eHealth literacy, Digital intervention on eHealth literacy, Lecture on general health
- Where
- China
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
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