Clinical trials: Age Problems
Age Problem
Efficacy of the Otago Exercise Program Delivered as Group Training Versus Individually Tailored Training
A non-inferiority controlled clinical trial using randomization for allocation at the level of general practice in 21 centers (in 8 Spanish regions), to compare a group Otago exercise program (OEP) [delivered by specifically…
- Trial name
- NCT03320668
- Testing
- Otago Exercise Program (OEP)
- Where
- 9 sites in Spain
- Volunteers
- 878 people, healthy volunteers welcome
- Sponsor
- Instituto de Salud Carlos III
Metabolic Diseases, Aging Problems
Brain Substrate Switch to Ketones and Lactate
The brain is constantly active and energetically expensive, making up a quarter of the body's energy budget despite occupying only 2% of its mass.
- Trial name
- BSS (NCT06000605)
- Testing
- Fed, Fasted
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Aging Problems
Vascular Aging and Microcirculation: Physiological Aspects of Vascular Aging in the Elderly Population (VAMP-Aging)
Rising life expectancy worldwide challenges public health due to increased cardiovascular disease linked to vascular aging, where microvascular dysfunction serves as an early indicator of system-wide inflammation, or…
- Trial name
- VAMP-Aging (NCT07563725)
- Testing
- Laser Speckle Contrast Imaging, Handgrip Dynamometry (Muscle Strength), Sit-to-Stand Test (5-Times Sit-to-Stand - 5STS)
- Where
- Brazil
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Frailty, Frailty Syndrome
Smart Home Technologies for Assessing and Monitoring Frailty in Older Adults
This project aims to address the impact of frailty on older adults, particularly its connection to cognitive impairments such as dementia.
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome, Pre-Frailty
- Trial name
- NCT05961319
- Testing
- Smart-Home Monitoring
- Where
- 2 sites in Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Aging Problems
Dose-response of Anteroposterior Mobilizations in Weight Bearing Talus Dorsiflexion
Ankle mobility limitations are common in older adults. A possible treatment to restore joint mobility is manual therapy based on mobilization techniques, in this case, applied on the ankle joint.
- Trial name
- ANKLE_WBROM (NCT04563663)
- Testing
- Posteriorization of the talus.
- Where
- Spain
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Age Problem, Healthy Aging
Resistance Training on Elderly Resilience
Background: There is on one hand sufficient evidence showing strong association between resilience and self-rated successful aging.
- Conditions
- Age Problem, Healthy Aging, Activity, Motor
- Trial name
- NCT04690465
- Testing
- Resistance training, Eight-form Yang-style Tai Chi program
- Where
- Hong Kong
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Aging Problems
Effectiveness of the Pilates Method to Prevent and Reduce Falls in Older People
The present research aims at evidencing the effect of one of the training methodologies increasingly demanded by the older adult, and used to promote, maintain and enhance physical and biopsychosocial aspects.
- Trial name
- NCT03299374
- Testing
- Pilates Intervention, Fall prevention intervention
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Auditory Perceptual Disorders, Aging Problems
Neuroplasticity in Auditory Aging_Project 2 Aims 1 and 2
Millions of elderly adults in the USA have age related hearing loss (ARHL), a malady that affects half of adults 60-69 years, and the majority of older adults.
- Trial name
- NCT03475043
- Testing
- Auditory training: temporal cues
- Where
- United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Pregnancy Complications
Measuring sVAP-1 as a Predictor of Pregnancy Problems
Pre-eclampsia is a common pregnancy disorder defined as high blood pressure and protein in the urine after 20 weeks of pregnancy.
- Trial name
- NCT04891315
- Testing
- Blood test for soluble VAP-1 (sVAP-1).
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Depression, Anxiety, Age Problem
Analysis of Anxiety and Depression Among Elderly People
This study is a single-center, cross-sectional, and survey study. Through questionnaire surveys, information about the anxiety and depression status of residents of elderly care institutions in Zhejiang Province is collected.
- Trial name
- NCT06006234
- Testing
- questionnaire survey
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Aging Problems, Balance; Distorted
Comparison of the Effects of Different Living Environments in Geriatric Individuals: A Pilot Study
In Turkey, 63% of geriatric people who make up approximately 8.3% of the entire population live in their own living environment, 36% live with their children and 1% live in nursing homes.
- Conditions
- Aging Problems, Balance; Distorted, Pain, Quality of Life
- Trial name
- NCT04873791
- Testing
- Assessment of geriatric individuals living in home environment and nursing home.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Age Problem
Relationship Between Respiratory Muscle Strenght, Peripheral Muscle Blood Flow and Gait Speed in the Elderly
The pourpose of this study is to verify if have relationship between respiratory muscle strenght, peripheral muscle blood flow and gait speed in the elderly.
- Trial name
- NCT04559659
- Testing
- Respiratory muscle strength
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Aging Problems
Explore Effects of Dietary Fish Oil in Human Skin
The purpose of this study is to explore the potential differences in the skin of people who take fish oil versus soybean oil pills.
- Trial name
- NCT03122912
- Testing
- Fish Oil, Soybean Oil
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Aging Well, Aging Problems
Aquatic Exercise for Cognition and Mobility in Older Adults
The purpose of this study is to assess the effects of an aquatic exercise program on cognition and physical function of older adults.
- Conditions
- Aging Well, Aging Problems, Cognitive Change, Gait, Unsteady
- Trial name
- NCT05501249
- Testing
- Aquatic Integrated Cognitive Motor Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Emily Dunlap
Cognition, Cognitive Performance
A Clinical Trial to Investigate the Safety and Efficacy of AP-Brain on Cognitive Performance at Varying Dosages in Healthy Middle-aged and Older Adults With Self-reported Memory Problems
The goal of this clinical trial is to investigate the safety and efficacy of AP-Brain on cognitive performance at varying dosages in healthy middle-aged and older adults with self-reported memory problems.
- Trial name
- NCT07388043
- Testing
- AP-Brain (1g), AP-Brain (3g), AP-Brain (5g)
- Where
- 2 sites in Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rousselot BVBA
Aging Problems
Effect of Floorball on Healthy Subjects
To investigate the effect of floorball on health and performance in healthy subjects over 65 years.
- Trial name
- NCT03371238
- Testing
- Floorball
- Where
- Denmark
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Mental Health Wellness 1, Mental Health Wellness 2
Internet Assisted Career-Oriented Soft-skills Training for Transition Age Youth with Mental Health Conditions
The purpose of this study is to evaluate the effectiveness of an internet- assisted Career-Oriented Work-Related Soft-skills Training (iCareer) intervention, infused with cognitive behavioral therapy, targeting individuals ages…
- Conditions
- Mental Health Wellness 1, Mental Health Wellness 2, Occupational Problems
- Trial name
- iCareer (NCT05766280)
- Testing
- iCareer Soft Skills Training for Employment
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Memory Deficits, Mood Change
The Effects of Microbiological Spectrum Changes to Improve Cognitive Health in Aging Population
The goal of this project is to develop probiotic dietary supplements intended for the elderly, which can modify the composition of the intestinal microbiota typically occurring in the aging population.
- Conditions
- Memory Deficits, Mood Change, Gut Health, Aging Problems
- Trial name
- CleverAgeBiota (NCT05051501)
- Testing
- Probiotics C2P
- Where
- 2 sites in Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health, Czech Republic
Problem of Aging
Volume Restoration of the Aging Midface With Sculptra Aesthetic
The purpose of this study is to examine the effect of Sculptra Aesthetic on the cosmetic rejuvenation of the midface complex. The investigators plan to both qualitatively determine the restoration of midface architecture as well…
- Trial name
- NCT01307865
- Testing
- injectable poly-L-lactic acid
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Williams Center Plastic Surgery Specialists
Sleep Problems, Maternal Anxiety
Sleep Patterns in Children Aged 0-36 Months and Maternal Anxiety and Depression
In this study, the investigators aimed to investigate the relationship between the sleep patterns of children aged 0-36 months hospitalized in the general pediatrics clinic and their mothers' anxiety and depression levels.
- Trial name
- NCT07476612
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital