Clinical trials: Alignment
Stuttering
Large Language Models for Stuttering Assessment and Therapy
This observational study aims to compare the quality of responses generated by four large language models (ChatGPT, Claude, Google Gemini, and Grok-4.20) to questions about stuttering.
- Trial name
- NCT07835347
- Testing
- ChatGPT-Generated Responses, Claude-Generated Responses, Google Gemini-Generated Responses
- Where
- Turkey (Türkiye)
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Istanbul Gelisim University
Orthodontics
Effect of Micro-osteo-perforations on the Rate of Alignment of Mandibular Anterior Teeth.
Micro osteoperforation is an easy, safe and effective method of accelerating orthodontic tooth movement by 2-3 times.it has been reported to increased the osteoblastic activity and some acceleration of the rate of canine…
- Trial name
- NCT05132764
- Testing
- Microosteoperforations
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rehman Medical Institute - RMI
Retinal Disease
Peripheral Retina Robotically Aligned OCT Study
Optical coherence tomography (OCT) is a 3D imaging technology that has seen wide adoption within ophthalmology. However, optical access to the retinal periphery remains a challenge for conventional OCT systems.
- Trial name
- PR-RAOCT (NCT06451068)
- Testing
- Peripheral retina robotically aligned optical coherence tomography (OCT) system, Likert Scales
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Non-secure Message Senders
eHealth Partnered Evaluation Initiative
On October 1, 2016, the VHA Office of Telehealth and the Connected Health Office will merge to create a single entity that will be responsible for the implementation and evaluation of eHealth technologies across the healthcare…
- Trial name
- eHealth PEI (NCT02665468)
- Testing
- Supported adoption intervention, Active comparator control
- Where
- 4 sites in United States
- Volunteers
- 1,196 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Intraocular Pressure
iCare IC1000 Alignment Study
The primary objective of this study is to evaluate the performance of the alignment feature of iCare IC1000 tonometer.
- Trial name
- NCT07022054
- Testing
- iCare IC1000 measurement
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icare Finland Oy
Aged, Asymptomatic Condition
Classification of the Sagittal Profile of the Spine in Asymptomatic Elderly Subjects
Principal aim The main purpose of the study is to describe the distribution of the sagittal profile in elderly subjects in order to bridge the gap present in this type of screening, evaluated in the literature for adults only…
- Trial name
- EOS60 (NCT03237039)
- Testing
- X-ray examination, fall-risk assessment, gait cycle analysis
- Where
- Italy
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Scapular Dyskinesis
Scapular Upward Rotation Exercises for Subjects With Deperessed Scapular Alignment
It was hypothesized that: There is no statistical significant effects of a scapular vupward rotation exercise (SURE) on scapular alignment in subjects with scapular downward rotation syndrome (SDRS).
- Trial name
- NCT04775251
- Testing
- Upward rotation exercise
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Neuro-Ophthalmology
Safety and Normative Data With Neos™
The goal of this clinical study is to collect standard data for the medical device neos™. neos™ is a system that shows images and measures the resulting eye movements and pupil size. Collecting standard data involves three steps.
- Trial name
- neos-SNOW (NCT07258212)
- Where
- 3 sites in Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- machineMD AG
Concussions
COmmunities Aligned to Reduce Concussion and Head Impact Exposure
Head impacts in collision sports such as football are a public health concern, as repetitive head impacts, even if a concussion is not suspected, have negative effects on brain health.
- Trial name
- COACH (NCT06624202)
- Testing
- COmmunities Aligned to reduce Concussion and Head impact exposure (COACH) Intervention
- Where
- United States
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Q-angle, Plantar Loading Patterns
Regional Associations Between Q-Angle and Plantar Loading in Active Young Adults
This observational study aims to examine the association between Q-angle and plantar loading characteristics in physically active young adults.
- Trial name
- NCT07500597
- Testing
- Q-angle and plantar pressure assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Harran University
Spinal Mobility, Thoracic Spine
Effects of Thoracic Spine Exercises on Spinal Alignment and Mobility in Male Soccer Players
Thoracic spine mobility is essential for trunk stability, rotational movement, and athletic performance in soccer players. This study aimed to investigate the effects of adding thoracic spine exercises to routine soccer training…
- Trial name
- NCT07253415
- Testing
- Thoracic spine exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Woman's Role, Men's Role
Comparison the Gender Effects of Knee Joint and Foot Complex Alignment During Single Leg Squat in Sedentaries
In this study, the investigators aimed to investigate the relationship between the dynamic valgus index and the dynamic valgus index during the landing phase of the single leg squat movement of sedentary people according to…
- Trial name
- NCT07262996
- Testing
- Sociodemographic profile, dynamic valgus index, single leg squat test, Q angle, Foot posture index, navicular drop test, pain assessment, muscle strength and flexibility tests
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istinye University
Pain Perception, Root Resorption
The Potential Effect of the Local Administration of Vitamins C and E on Orthodontic Treatment: A Randomized Clinical Trial
Brief Summary of the Study This study investigates the effects of locally administered vitamins C and E on orthodontic tooth movement during the initial stage of treatment.
- Conditions
- Pain Perception, Root Resorption, Rate of Orthodontic Tooth Movement, Biomarkers
- Trial name
- NCT06847880
- Testing
- 1: Vitamin C Supplementation, Vitamin E Supplementation, Saline Solution (Control)
- Where
- 3 sites in Iraq
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Fourth Cranial Nerve Palsy
Teeth and Jaw Misalignment in Patients Suffering From Congenital Fourth Cranial Nerve Palsy
Patients suffering from congenital fourth cranial nerve palsy may have misalignment of jaws as well as teeth due to head tilt in childhood.
- Trial name
- IVPareseZahn (NCT02149355)
- Testing
- teeth molding
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Osteoarthritis, Knee
Muscle Property, Alignment and Joint Loading in People With Knee Osteoarthritis
Knee osteoarthritis (KOA) is a common chronic painful musculoskeletal condition among older adults. It poses great challenge to the health care system due to its inability to be cured.
- Trial name
- NCT03628508
- Testing
- Exercise
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Obesity (Disorder), Morbid Obesity
Chrono-ALIGN: A Chronotype-Based Chrono-Nutrition Intervention in Post-Bariatric Patients
This randomized controlled trial will evaluate the impact of chrono-nutrition, a dietary approach that aligns meal timing with the body's circadian rhythms, on weight change, metabolic outcomes, appetite, and gut microbiota in…
- Conditions
- Obesity (Disorder), Morbid Obesity, Bariatric Sleeve Gastrectomy, Meal Time
- Trial name
- Chrono-ALIGN (NCT07324044)
- Testing
- Standard Post-Bariatric Care (Control), Early Time-Restricted Eating (eTRE), Chronotype-Based Chrono-Nutrition (CB-CN)
- Where
- Saudi Arabia
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- King Saud University
Primary Osteoarthritis of Knee Nos
A Prospective Study to Evaluate Robot Assisted Total Knee Replacement Outcomes
This study aims to see if outcomes for patients that receive the traditional total knee replacement surgical technique are different than the outcomes for patients that receive robot-assisted total knee replacement.
- Trial name
- NCT03523897
- Testing
- Robot Assisted Total Knee Replacement, Traditional Total Knee Replacement
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Osteo Arthritis Knee
Traditional Versus Alternative Alignment in TKR
As many as 20% of patients are unhappy with the results of total knee replacement (TKR). Various changes to surgical technique have tried to address this but have not led to a significant improvement in the numbers of patients…
- Trial name
- NCT03196011
- Testing
- TKR with mechanical alignment method, TKR with alternative alignment method
- Where
- United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Malocclusion
The Effect of OrthoPulse™ Photobiomodulation on Tooth Movement and Treatment Time When Used With Invisalign Treatment
The aim of the study is to determine if, and to what degree photobiomodulation treatment with OrthoPulse has an effect on the rate of tooth movement during alignment for patients receiving Invisalign orthodontic aligner treatment.
- Trial name
- NCT02954133
- Testing
- Invisalign (7 day), Invisalign (5 day), OrthoPulse
- Where
- 4 sites in United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Alignment, Leveling and Alignment of Teeth
Improving the Treatment Outcome Related to Inclination of Mandibular Incisors by Separating Aligning and Leveling Phases.
Study Summary The goal of this clinical trial is to determine whether separating the aligning and leveling phases during fixed orthodontic treatment improves the treatment outcome related to the inclination of mandibular incisors…
- Trial name
- Alignment (NCT07733258)
- Testing
- Separating phases of alignment and leveling using heat activated niti archwire
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences