Clinical trials: Anesthesia for Cesarean Delivery
Pregnancy Complications, Cesarean Section Complications
A Quality Improvement Project - Peripartum Operating Room Leveling System
Investigators propose a four-category triaging system to delineate and facilitate the communication and action plan for all types of obstetric OR cases via a multidisciplinary approach.
- Conditions
- Pregnancy Complications, Cesarean Section Complications, Morbidity;Perinatal
- Trial name
- NCT03552419
- Volunteers
- 1,380 people
- Sponsor
- Johns Hopkins University
Cesarean Section (MeSH: D002585), Anesthesia
Evaluation of Consciousness Depth (qCON) and Analgesia Depth (qNOX) Indices in General Anesthesia
Objective: This prospective, single-center, observational clinical study aims to evaluate changes in qCON (hypnotic depth), qNOX (nociception/analgesia depth), EMG, and other parameters in patients undergoing elective cesarean…
- Conditions
- Cesarean Section (MeSH: D002585), Anesthesia, Intraoperative Awareness, Analgesia
- Trial name
- NCT07887919
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kudret Dogru
Cesarean Section Surgery, TAP Blocks
Post-Cesarean Gastrointestinal Dysfunction
General anesthesia has a range of effects that can lead to gastrointestinal (GI) system dysfunctions in the postoperative period.
- Conditions
- Cesarean Section Surgery, TAP Blocks, Gastrointestinal Dysfunction
- Trial name
- NCT07067021
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Cesarean Section, Postoperative Pain After Cesarean Section
Nociception Level Index Monitoring During Cesarean Section
This prospective randomized controlled trial evaluated the effect of nociception level (NOL) index-guided intraoperative analgesia on postoperative pain management in patients undergoing elective cesarean section under general…
- Conditions
- Cesarean Section, Postoperative Pain After Cesarean Section, Pain Management
- Trial name
- NOL-CS (NCT07720440)
- Testing
- Nociception Level Index Monitoring, Standard Intraoperative Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istinye University
Anesthesia, Cesarean Section Complications
Comparative Study Among Different Doses of Ephedrine During Elective Cesarean Section Under Subarachnoid Block.
compare the time of second hypotension after administration of three different doses of ephedrine 5,10,15 mg
- Conditions
- Anesthesia, Cesarean Section Complications, Subarachnoid Block
- Trial name
- NCT05993182
- Testing
- Ephedrine 5mg, Ephedrine 10mg, Ephedrine 15mg
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Aswan University
Cesarean Delivery
Prevention of Intraoperative Nausea and Vomiting During Cesarean Section
The study investigates the incidence of intraoperative nausea and vomiting under spinal anesthesia using a phenylephrine infusion with and without prophylactic antiemetics.
- Trial name
- NCT01216410
- Testing
- Metoclopramide, Phenylephrine infusion, Combination Group
- Where
- United States
- Volunteers
- 306 people
- Sponsor
- Duke University
Intracranial Pressure Increase
Comparison of ONSD and rSO2 Measurements Between General and Spinal Anesthesia in C-Section
General anesthesia and regional anesthesia can be chosen in cesarean operations. Endotracheal intubation and mechanical ventilation are components of general anesthesia.
- Trial name
- NCT04446013
- Testing
- Optic Nerve Sheath Diameter Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Cesarean Section Complications, Spinal Anesthetic Complications
Hemodynamic Effect of Left Tilting in Cesarean Delivery
The aim of this work is to investigate the effect of different angles of lateral tilt on the maternal hemodynamics before and after subarachnoid block
- Trial name
- NCT03181776
- Testing
- left lateral tilting in 15 degrees, left lateral tilting in 30 degrees, supine position
- Where
- Egypt
- Volunteers
- 61 people
- Sponsor
- Cairo University
Caesarean Section
Use of Vasopressors in Hypotension Associated With Spinal Anaesthesia in Caesarean Sections
This study was designed as a prospective randomised study. In this study, the researchers planned to evaluate the effect of intravenous vasopressor agents administered to patients undergoing caesarean section under spinal…
- Trial name
- NCT07384455
- Testing
- Patients who received 10 mg of ephedrine intravenously after spinal anaesthesia during caesarean section, Patients who received 8 mcg intravenous norepinephrine after spinal anaesthesia during caesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Anesthesia; Adverse Effect, Spinal and Epidural
Granisetron Versus Pethidine in Treatment of Post Spinal Shivering in Cesarean Sections
Granisetron Versus Pethidine in Treatment of Post Spinal Shivering in Cesarean Sections
- Trial name
- NCT06513806
- Testing
- Granisetron 1 Mg/mL Intravenous Solution, Pethidin
- Where
- Egypt
- Volunteers
- 330 people
- Sponsor
- Ain Shams University
Hypotension, Anesthesia
Development of Advanced Double Intravenous Vasopressor Automated (ADIVA) System
Maternal hypotension during spinal anaesthesia for Caesarean delivery may bring various adverse effects. It is therefore important to closely monitor hypotension during spinal anaesthesia, however current technology does not…
- Trial name
- ADIVA (NCT03620942)
- Testing
- Phenylephrine, Ephedrine, ADIVA System
- Where
- Singapore
- Volunteers
- 173 people
- Sponsor
- KK Women's and Children's Hospital
Pre-Eclampsia, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Electroencephalographic Effects of Spinal Anaesthesia During Caesarean Delivery in Preeclampsia
Neuraxial anesthesia has been associated with delayed brainstem conduction and decreasing afferent sensory transmission, thereby modifying reticulo-thalamo-cortical mechanisms regulating arousal.
- Trial name
- NCT03917342
- Testing
- EEG measure
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cesarean Section
Fluid Management for Cesarean Section III
Regional anesthesia, including epidural, spinal and combined epidural spinal anesthesia (CSEA), is a pivotal part in modern anesthesiology.
- Trial name
- FMCS-III (NCT00973414)
- Testing
- Ringer's Lactate, Six percent hydroxyethyl starch
- Where
- China
- Volunteers
- 850 people
- Sponsor
- Nanjing Medical University
Obesity, Pregnancy
A Trial of the Use of Ultrasound to Aid the Insertion of Combined Spinal Epidural Anaesthesia
The study will establish whether the use of ultrasound scanning with a purpose built probe will aid the insertion of the needles for epidural and spinal anaesthesia for obese women undergoing elective caesarean section The study…
- Trial name
- NCT00166699
- Testing
- ultrasound
- Where
- 5 sites in United Kingdom
- Volunteers
- 42 people
- Sponsor
- NHS Greater Glasgow and Clyde
Anesthesia, Adverse Effect
Comparison of Two Doses of Norepinephrine in Preventing Hypotension After Spinal Anesthesia
The purpose of the study is to determine the more effective intravenous bolus of norepinephrine for maintaining blood pressure during a spinal anesthesia for a cesarean delivery with the fewer side effects.
- Conditions
- Anesthesia, Adverse Effect, Hypotension, Cesarean Section Complications
- Trial name
- NCT03706755
- Testing
- Norepinephrine: 1mcg/kg, Norepinephrine 0,5mcg/kg
- Where
- Tunisia
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Bradycardia, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Hyoscine Butylbromide for Prevention of Bradycardia During Cesarean Section
The aim of this study is to assess the efficacy of Iv hyoscine butylbromide in preventing Bradycardia during cesarean section under spinal anaesthesia with local anaesthetic and morphine.
- Conditions
- Bradycardia, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use, Cesarean Section Complications
- Trial name
- NCT04069078
- Testing
- Hyoscine Butylbromide 20 Mg/mL Solution for Injection Ampoule, Normal saline
- Where
- Egypt
- Volunteers
- 173 people
- Sponsor
- Assiut University
Spinal Anesthesia, Hypotension
Prediction of Spinal Anesthesia-Induced Hypotension in Cesarian Section: Carotid Artery-Corrected Flow Time Versus Cardiometry
This research aimed to evaluate and compare the role of carotid corrected flow time (FTc) and electrical cardiometry (EC) in the prediction and prevention of post-spinal hypotension in elective cesarian section.
- Conditions
- Spinal Anesthesia, Hypotension, Cesarian Section, Carotid Artery
- Trial name
- NCT06236217
- Testing
- Carotid Ultrasound, Electrical cardiometry
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Tanta University
Labor Pain, Cesarean Delivery Regional Anesthesia Induction
Neuraxial Ultrasound Device Study
The aim of the study is to develop a device that can eliminate failed neuraxial placements in challenging patients.The study will attempt to improve safety and efficacy of neuraxial anesthesia with high precision real-time needle…
- Trial name
- NCT06281249
- Testing
- Ultrasound placement device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary
Magnesium for Neonatal Neuroprotection and Mothers
Magnesium is a treatment for mothers to protect brains of babies born early. This study investigates combined effects of magnesium and spinal or epidural anesthesia on mothers having cesareans.
- Conditions
- Premature Birth, Sedation During Labor and Delivery; Complications, Pulmonary, Respiratory Depression
- Trial name
- MnMs (NCT01482078)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Anesthesia, Spinal
Intrathecal Dexmedetomidine With Bupivacaine for Spinal Anesthesia in Cesarean Section
A Randomized, Controlled, Double blind study aiming to evaluate the analgesic potentials and side effect profile of different dose levels of Dexmedetomidine added to subarachnoid bupivacaine in full-term pregnant women undergoing…
- Trial name
- NCT02365857
- Testing
- Dexmedetomidine & Bupivacaine., Bupivacaine Only.
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University