Clinical trials: Arteriosclerosis of Coronary Artery Bypass Graft
Coronary Artery Bypass Graft Surgery, Coronary Artery Disease
Cardiac Rehabilitation in Coronary Artery Bypass Graft Surgery
This randomized controlled trial investigates the comparative effects of a combined preoperative and postoperative cardiac rehabilitation program versus a postoperative-only program on functional capacity, pulmonary function…
- Trial name
- NCT07006441
- Testing
- Preoperative Cardiac Rehabilitation, Postoperative Cardiac Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Atlas University
Heart Disease, Myocardial Ischaemia
Safety and Efficacy Study of Hybrid Revascularization in Multivessel Coronary Artery Disease
The purpose of the study is to assess the safety and efficacy of hybrid revascularization in comparison with coronary artery bypass grafting among patients with multivessel coronary artery disease.
- Conditions
- Heart Disease, Myocardial Ischaemia, Coronary Disease, Coronary Artery Disease
- Trial name
- POL-MIDES (NCT01035567)
- Testing
- Hybrid revascularization, Coronary Artery Bypass Grafting
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Silesian Centre for Heart Diseases
Aortic Valve Disease, Coronary Artery Disease
Early Outcomes of Concomitant Transcatheter Aortic Valve Implantation and Off-pump Coronary Artery Bypass Grafting in Management of Severe Symptomatic Aortic Stenosis and Coronary Artery Disease
Study Objectives/Specific Aims Overall Goal: To study the outcomes of patients undergoing TAVI, their subsequent results and complications.
- Trial name
- NCT04525339
- Testing
- TAVI and Off pump CABG
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Assiut University
Coronary Artery Disease, Atrial Fibrillation
The Effect of Colchicine on the Occurrence of Atrial Fibrillation After Cardiac Surgery
Development of a new comprehensive method for perioperative prevention of atrial fibrillation paroxysms in cardiac surgery patients at the hospital stage.
- Conditions
- Coronary Artery Disease, Atrial Fibrillation, Coronary Artery Bypass Grafting, Colchicine
- Trial name
- CAFE (NCT06798714)
- Testing
- NSAID, Colchicine 0.5 MG
- Where
- Russia
- Volunteers
- 140 people
- Sponsor
- Tomsk Cardiology Research Institute
Biomarkers, Coronary Artery Bypass Surgery
Dynamics of microRNA Expression and Systemic Inflammatory Response in POCD After Cardiac Surgery
Postoperative cognitive decline (POCD) is one of the most common complications after cardiac surgery. It is characterized by impaired memory, attention, and executive functions and can have long-term consequences.
- Conditions
- Biomarkers, Coronary Artery Bypass Surgery, Interleukin-6, MicroRNAs
- Trial name
- NCT07231731
- Where
- Croatia
- Volunteers
- 48 people
- Sponsor
- Osijek University Hospital
Ischaemic Heart Disease, Contrast-induced Nephropathy
Randomised Controlled Trial to Assess Whether Computed Tomography Cardiac Angiography Can Improve Invasive Coronary Angiography in Bypass Surgery Patients
A large number of patients with symptomatic ischaemic heart disease undergo coronary artery bypass grafting (CABG) to alleviate their symptoms and improve prognosis.
- Trial name
- BYPASS-CTCA (NCT03736018)
- Testing
- CTCA
- Where
- United Kingdom
- Volunteers
- 688 people
- Sponsor
- Queen Mary University of London
Coronary Artery Disease, Coronary Artery Bypass Surgery
Double-Blind Comparison of Combined General-Spinal Anesthesia to General Anesthesia for Coronary Artery Surgery
Use of neuraxial agents in anesthesia for cardiac surgery is expanding. We have used combined general-spinal anesthesia for cardiac surgery for 12 years.
- Trial name
- NCT00242697
- Testing
- spinal analgesia and anesthesia for coronary artery surgery
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- University of Calgary
Prevention & Control
Rivaroxaban for the Prevention of Major Cardiovascular Events in Coronary or Peripheral Artery Disease
The primary objectives of this study are: To determine whether rivaroxaban 2.5 mg twice daily (bid) + aspirin 100 mg once daily (od) compared with aspirin 100 mg od reduces the risk of a composite of myocardial infarction…
- Trial name
- COMPASS (NCT01776424)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Aspirin, Pantoprazole
- Where
- 565 sites in United States, Argentina and 31 more
- Volunteers
- 27,395 people
- Sponsor
- Bayer
Heart Failure, Arteriosclerosis of Coronary Artery Bypass Graft or Other Coronary Reperfusion
PAC-IC-SAOS Obstructive Sleep Apnea Syndrome and Ventricular Function
The aim of this clinical trial is to evaluate the effect of obstructive sleep apnea syndrome (OSAS) treatment in heart failure patients following coronary artery bypass graft (CABG) surgery or other coronary reperfusion.
- Conditions
- Heart Failure, Arteriosclerosis of Coronary Artery Bypass Graft or Other Coronary Reperfusion, Sleep Apnea, Obstructive
- Trial name
- PAC-IC-SAOS (NCT01900379)
- Testing
- CPAP treatment
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Grenoble
Coronary Artery Disease
The Effect Of Antiplatelets Therapy On Saphenous Vein Coronary Artery Bypass Graft Patency
This protocol is designed to evaluate the effect of antiplatelets (Tirafiban and Prasugrel) on the incidence of early and intermediate graft patency after CABG.
- Trial name
- NCT01598337
- Testing
- Aspirin, Tirofiban, Clopidogrel
- Where
- Saudi Arabia
- Volunteers
- 200 people
- Sponsor
- Prince Sultan Cardiac Center, Adult Cardiology Department.
Coronary Artery Bypass Grafting, Remimazolam
Remimazolam for Postoperative Atrial Fibrillation
Atrial fibrillation (AF) is the most common cardiac severe arrhythmia globally and is associated with an increased risk of mortality and morbidity, with a loss of 6.0 million disability-adjusted life-years worldwide in 2017…
- Trial name
- RePAF (NCT05891145)
- Testing
- Remimazolam, midazolam
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Yangzhou University
Coronary Artery Disease, Post Coronary Artery Bypass Grafting
Aerobic and Resistance Training in Post-CABG Patients
This study investigates the effect of combined aerobic and resistance training using resistance bands on diaphragmatic excursion and pulmonary function (FVC, FEV₁, PEF) in post-CABG patients undergoing phase II cardiac…
- Trial name
- NCT07034937
- Testing
- Combination of aerobic training (treadmill walking) and resistance training
- Volunteers
- 15 people
- Sponsor
- Universitas Padjadjaran
Ischemic Heart Disease, Coronary Artery Disease
Impact of Acute Normovolemic Hemodilution on Blood Viscosity
Acute normovolemic hemodilution (ANH) has long been employed for reducing allogenic blood transfusion for cardiac surgery, and hydroxyethyl starch has been used as an intravenous replacement fluid during ANH procedure.
- Trial name
- NCT03366753
- Testing
- acute normovolemic hemodilution, In-vitro hemodilution
- Where
- South Korea
- Volunteers
- 21 people
- Sponsor
- Konkuk University Medical Center
Coronary Artery Disease, Mitral Valve Insufficiency
Mitral Valve Repair Combined Coronary Artery Bypass Grafting(CABG) Verus CABG Alone on Functional Ischemic Mitral Regurgitation
Coronary artery bypass grafting(CABG) is an effective procedure in treating severe coronary artery disease(CAD). Optimal surgical method for CAD patients with functional ischemic mitral regurgitation(FIMR) is still controversial.
- Trial name
- NCT03525041
- Testing
- CABG, mitral valve annuloplasty
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Artery Disease, Coronary Artery Disease With Myocardial Infarction
Comparing a New Technique of Combining Carbon-dioxide With Electrocautery With Usual Technique of Stand-alone Electrocautery for Taking Down Left Internal Mammary Artery for Coronary Artery Bypass(CABG)
The goal of this study is to compare the efficacy of a new harvesting technique for an arterial conduit(LIMA - Left Internal Mammary artery) in patients undergoing Coronary artery bypass grafting.
- Trial name
- CABG (NCT06155045)
- Testing
- Modified Carbo-dissection Technique, Conventional Arm
- Where
- India
- Volunteers
- 46 people
- Sponsor
- Government Medical College Kottayam
Coronary Artery Disease (CAD);, Myocardial Infarction (MI)
A Multicentre Trial on the Effectiveness of Physical Rehabilitation of Patients With Coronary Artery Disease: Aerobic Interval Training Versus Moderate Continuous Training.
Cardiac rehabilitation, including physical training, has become accepted treatment following myocardial infarction, coronary stent implantation and coronary bypass operation.
- Conditions
- Coronary Artery Disease (CAD);, Myocardial Infarction (MI), Percutaneous Coronary Intervention (PCI), Coronary Artery Bypass Grafting (CABG)
- Trial name
- SAINTEX-CAD (NCT01226225)
- Testing
- Aerobic interval training, Moderate endurance training
- Where
- 2 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Antwerp
Coronary Artery Disease
Clinical Outcomes of Patients Undergoing CABG Surgery With VEST Supported Venous Grafts
This is a prospective, investigator-initiated, multi-center, open label and post-market registry, enrolling patients with atherosclerotic coronary artery disease, scheduled for CABG with at least one SVG bypass.
- Trial name
- NCT04761068
- Testing
- VEST
- Where
- 13 sites in Austria, Germany and 3 more
- Volunteers
- 1,000 people
- Sponsor
- Cardiocentro Ticino
Coronary Artery Bypass Grafting (CABG) Surgery, Coronary Artery Disease
Prospective Study Protocol for Multiparametric PCCT Assessment of Early Ventricular Outcomes After CABG
The goal of this observational study is to learn whether information about heart muscle tissue from preoperative photon-counting CT, a newer type of CT scan, can help predict heart recovery 3 months after coronary artery bypass…
- Trial name
- PCCT-CABG (NCT07883499)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xin Lou
Coronary Artery Disease, Complication of Coronary Artery Bypass Graft
Negative Pressure Dressing After Saphenous Vein Harvest
This study will test the effectiveness of negative pressure wound therapy (using the VAC Prevena device, KCI Canada Inc.) applied to the saphenous vein harvest site after Coronary Artery Bypass Grafting (CABG).
- Conditions
- Coronary Artery Disease, Complication of Coronary Artery Bypass Graft, Wound Complication
- Trial name
- NCT01698372
- Testing
- Prevena device (Group A)
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of Calgary
Coronary Artery Disease
The Effect of Resistance Training on Proprotein Subtilisin Convertase Kexin 9 Level After Coronary Bypass Surgery
This research add resistance training to patients who undergo cardiac rehabilitation program after coronary bypass surgery, comparing the level of PCSK9 level on that group to another group who receives conventional…
- Trial name
- NCT02674659
- Testing
- resistance training, aerobic training
- Volunteers
- 87 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia