Clinical trials: Back Disorder, open to volunteers
Music Therapy for Pain and Sedation, Neck Pain Musculoskeletal
Musical Mindfulness for Pain in the ED Waiting Room
Studies have shown that 60-70% of patients in the Emergency Department (ED) experience pain. With pain being such a broad issue in the ED, the ED is expected to deliver safe and effective treatment of pain.
- Conditions
- Music Therapy for Pain and Sedation, Neck Pain Musculoskeletal, Back Pain
- Trial name
- NCT07391891
- Testing
- Music intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Irvine
Spinal Disease, Neck Pain
Safety and Effectiveness of Ultrasound-guided Pharmacopuncture for Spinal Diseases
This multi-center registry study aims to evaluate the safety and effectiveness of ultrasound-guided pharmacopuncture for patients diagnosed with spinal diseases.
- Conditions
- Spinal Disease, Neck Pain, Low Back Pain, Radiculopathy
- Trial name
- NCT07543692
- Testing
- Ultrasound-guided Pharmacopuncture
- Where
- 6 sites in South Korea
- Volunteers
- 600 people
- Sponsor
- Jaseng Medical Foundation
Fibromyalgia, Lupus Erythematosus, Systemic
Brief Pain Exposure Therapy (BPET) For Nociplastic Pain
This study is intended to test whether a brief Zoom-based behavioral treatment can help adults with fibromyalgia (FM), Lupus, chronic pelvic pain, and chronic low back pain learn effective strategies for reducing pain, disability…
- Conditions
- Fibromyalgia, Lupus Erythematosus, Systemic, Chronic Pelvic Pain, Chronic Low Back Pain (CLBP)
- Trial name
- BPET (NCT06208514)
- Testing
- Brief pain exposure therapy (BPET)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Michigan
Low Back Pain, Chronic
A Prospective Study to Evaluate the Efficacy of Iovera Lumbar Medial Branch Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Chronic Low Back Pain
A research study is being conducted to compare two treatments for long-term low back pain: One uses the iovera° system, which applies cold to certain nerves in the lower back.
- Trial name
- NCT07214844
- Testing
- Iovera Medial Branch Cryoneurolysis, Radiofrequency ablation (RFA)
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Montefiore Medical Center
Patients Undergoing Arthroscopic Knee Surgery
Evaluation of the Effectiveness of iPACK and Adductor Canal Blocks on Patients Undergoing Arthroscopic Knee Surgery
Arthroscopic knee surgery is one of the most commonly performed procedures in orthopedic surgery. More than 50% of patients experience moderate to severe pain after the operation.
- Trial name
- NCT07002580
- Testing
- IPACK and adductor canal block with Bupivacaine 0.25%, Spinal Anesthesia with Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Sakarya University
Pulmonary Nodules, Nerve Block
Local Anaesthetic Spread and Sensory Block Range of the Retro-superior Costotransverse Ligament Space Block
The aim of this clinical trial is to investigate the effects of local anesthetic diffusion range and sensory block range during retro-SCTLB(retro superior costotransverse ligament space block) and TPVB(thoracic paravertebral…
- Trial name
- NCT07153263
- Testing
- Ultrasound-guided retro-SCTLB, Ultrasound-guided TPVB
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Alzheimer Disease, Early Onset, Posterior Cortical Atrophy
MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A PET/MR STUDY
Patients with Alzheimer's disease and with early onset of symptoms (<65 years) (AD-Y) have a multi-domain cognitive deficit, whereas memory disorders (typical of the elderly patient's AD) are less often in the foreground.
- Trial name
- PET-AL (NCT04150198)
- Testing
- TEP/IRM
- Where
- 2 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Basilar Artery Occlusion
Extending the Time Window for Tenecteplase by Recanalization of Basilar Artery Occlusion in Posterior Circulation Stroke
Patients presenting to the emergency department with an acute ischemic stroke due to basilar artery occlusion within 24 hours of stroke onset will be assessed to determine their eligibility for randomization into the trial.
- Trial name
- POST-ETERNAL (NCT05105633)
- Testing
- Tenecteplase, Standard Care (which may include intravenous Alteplase)
- Where
- 17 sites in Australia, Brazil and 1 more
- Volunteers
- 688 people
- Sponsor
- University of Melbourne
Posterior Fossa Lesion
Comparison of Surgical Outcomes of Craniotomy and Craniectomy in Posterior Fossa Lesions
The purpose of this randomized controlled trial is to compare the surgical outcomes of craniotomy and craniectomy among patients with posterior fossa lesions.
- Trial name
- NCT06831695
- Testing
- Craniotomy, Craniectomy
- Volunteers
- 80 people
- Sponsor
- University of Health Sciences Lahore
Low Back Pain, Chronic
Comparative Effects of Group Based Exercises with and Without Cognitive Functional Therapy on Clinical Outcomes in Patients with Chronic Low Back Pain
1.1Research objective The objective of the study is to find the comparative effects of group based exercises with and without cognitive functional therapy on clinical outcomes in patients with chronic low back? 1.2 Hypothesis…
- Trial name
- NCT06759675
- Testing
- group based exercise with Cognitive functional therapy, Group based exercise
- Volunteers
- 40 people
- Sponsor
- University of Faisalabad
Spine Injury, Cord Injury, Spinal
The Outcome of Injured Cervical Spinal Cord With Uncontrolled Swelling Under Duraplasty
Overall Objective: To assess whether incorporating duraplasty alongside bony decompression enhances motor function outcomes in individuals following Traumatic Spinal Cord Injury (TSCI).
- Conditions
- Spine Injury, Cord Injury, Spinal, Cord Infarction Spinal, Incomplete Spinal Cord Injury
- Trial name
- NCT06552507
- Testing
- Duroplasty
- Where
- Taiwan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Local Anesthesia, Dental Implants
Comparison of Anesthetic Efficacy and Safety Between Inferior Alveolar Nerve Block and the Infiltrative Technique for the Treatment of Peri-implant Diseases in Posterior Mandibular Implants
This triple-blind randomized clinical trial aims to compare the anesthetic efficacy and safety of two local anesthesia techniques for the surgical treatment of peri-implantitis in posterior mandibular implants: inferior alveolar…
- Conditions
- Local Anesthesia, Dental Implants, Periimplantitis
- Trial name
- NCT07590037
- Testing
- Comparison of anesthetic efficacy and safety between nerve block and infiltrative technique for periimplantitis surgical treatment in poosterior mandibular implants
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Male Urogenital Diseases
Early Oxybutinin Treatment for Boys With Posterior Urethral Valves
Boys with posterior urethral valves have bladder dysfunction of varying severity. Early treatment of these children with anticholinergics is recommended by some teams, although there have never been any clear studies on the…
- Trial name
- PRETIPUV (NCT04526353)
- Testing
- Oxybutynin 1 mg/ml Syrup
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Cervical Radiculopathy
Relationship Between Craniovertebral Angle, Lumbar Proprioception, and Trunk Muscle Strength in Cervical Radiculopathy
The study aimed to Investigate the relation of cranio-vertebral angle with lumbar proprioception in patients with cervical radiculopathy.
- Trial name
- NCT07240090
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Basma Ashraf Ali Mohamed
Cervical Spine Fusion
Multifidus Cervicis Plane Block Vs. Sham Block For Posterior Cervical Spine Fusion Surgery
The goal of this randomized, double-blinded, clinical trial is to assess the benefit of administering a Multifidus Cervicis Plane (MCP) block compared to a sham block as a method of postoperative pain control in patients…
- Trial name
- MCP (NCT05996133)
- Testing
- Bupivacaine Hcl 0.25% Inj, Normal saline
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Hartford Hospital
Postoperative Acute Pain, Breast Cancer
IPP-PSP Block vs. SPSIPB in Breast Surgery
This prospective, randomized clinical study aims to compare the analgesic efficacy of the interpectoral-pectoserratus plane block and the serratus posterior superior intercostal plane block for postoperative pain management in…
- Conditions
- Postoperative Acute Pain, Breast Cancer, Regional Anesthesia
- Trial name
- NCT07246720
- Testing
- Interpectoral-Pectoserratus Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Zonguldak Bulent Ecevit University
Tooth, Nonvital, Dental Restoration
Additive vs Subtractive Manufacturing for Endocrown Fabrication: A 24-Month RCT
This randomized controlled trial (RCT) compares the 24-month clinical performance of endocrown restorations fabricated by two digital manufacturing pathways: additive manufacturing using 3D-printed ceramic-filled photopolymer…
- Conditions
- Tooth, Nonvital, Dental Restoration, Endodontically Treated Teeth
- Trial name
- ENDO-3D (NCT07633574)
- Testing
- CAD/CAM Milled HC Hard Block Endocrown, 3D-Printed VarseoSmile TriniQ Endocrown
- Volunteers
- 60 people
- Sponsor
- Cairo University
Low Back Pain, Spine Disease
Effect of an Interdisciplinary Spine Rehabilitation Program
The goal of this research project is to evaluate the effectiveness of the current interdisciplinary rehabilitation program (Revita) and follow-up trajectory for chronic lumbar spine disorders in the University Hospitals Leuven.
- Trial name
- PROGRESS (NCT06030570)
- Testing
- Rehabilitation program (Revita)
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- KU Leuven
Noninfectious Posterior Uveitis, Uveitis, Posterior
Frequency and Intensity of Inflammatory Relapses in Patients With Non-infectious Posterior Uveitis Treated With a Fluocinolone Acetonide Implant
Non-infectious posterior uveitis is a chronic inflammatory eye disease that can lead to irreversible retinal damage and visual impairment due to repeated inflammatory relapses.
- Conditions
- Noninfectious Posterior Uveitis, Uveitis, Posterior, Uveitic Macular Edema
- Trial name
- FIRE (NCT07423442)
- Testing
- fluocinolone acetonide intravitreal implant
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
MECHANICAL BACK PAIN, Sleep Quality
Investigation of the Effect of Thoracic Manipulation and Classical Massage on Pain, Flexibility and Sleep Quality
Investigation Of The Effects Of Thoracic Manipulation And Classical Massage On Pain Flexibility And Sleep Quality In Patients With Mechanical Back Pain
- Trial name
- NCT07518732
- Testing
- Classical Massage, Manual therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ayşe BAŞAYAN