Clinical trials: Balance
Drug-induced QT Prolongation, Pharmacokinetics
Ability of Late Sodium or Calcium Current Block to Balance the ECG Effects of Potassium Current Block
The primary objective of this research study is to test the hypothesis that late sodium current blocking drugs (mexiletine or lidocaine) can attenuate the effect of hERG potassium channel blocking drugs (dofetilide) on…
- Conditions
- Drug-induced QT Prolongation, Pharmacokinetics, Pharmacodynamics
- Trial name
- NCT02308748
- Testing
- Dofetilide, Mexiletine, Lidocaine
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Food and Drug Administration (FDA)
Fasting State
Bioequivalence Study of Ondansetron Tablets USP 8 mg Under Fasting Condition
This is a randomized, open Label, balanced, two-treatment, two-period, two-sequence, single dose, cross over pivotal study. The purpose of this study is to assess the bioequivalence between Test Product and the corresponding…
- Trial name
- NCT01578252
- Testing
- Ondansetron Tablets USP 8 mg, Ondansetron Hydrochloride
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- IPCA Laboratories Ltd.
Disease Prevention
Gamified Digital Balance Assessment
A randomized controlled trial involving 30 older adults will compare the digitalized Brief-BESTest and the GDBA. Quantitative outcomes included perceived exertion, enjoyment, competence, pressure, and intention to continue use.
- Trial name
- NCT07088848
- Testing
- Gamified Digital Balance Assessment, Digitalized Brief-BESTest design
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Sacroiliac Dysfunction
Sacroiliac Joint Dysfunction Consequences and Its Reversal by Manipulation
Sacroiliac joint dysfunction (ASI) is an alteration in the normal biomechanics of the joint, which leads to hypomobility or hypermobility of that joint.
- Trial name
- LOUIS (NCT06710535)
- Testing
- Manual Manipulation
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Falls, Balance Assessment
Developing a Daily-use Fall Risk Assessment Device in Clinical Setting
Study Objectives Objective 1: Compare the fall risk assessment results between balance sensors, traditional tests, and clinical diagnoses.
- Trial name
- NCT06767163
- Testing
- iBalance
- Where
- Hong Kong
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Sarcopenic Obesity, Sarcopenia
Effects of Obesity on Rectus Femoris Muscle Thickness, Sarcopenia, Gait and Balance in Women
Research; It is a planned, non-invasive, controlled study in obese female volunteers and non-obese female volunteers. The population of the study consists of voluntarily non-obese women and obese women.
- Conditions
- Sarcopenic Obesity, Sarcopenia, Obesity
- Trial name
- NCT05638035
- Testing
- Ultrasonografi, Sarcopenia measurement, Zebris
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Healthy Subjects
An Open-label Trial to Evaluate Mass Balance of Tavapadon at Steady State in Healthy Subjects
The purpose of this trial is to determine the absorption, metabolism, and excretion (AME) of [14C] tavapadon.
- Trial name
- NCT04241393
- Testing
- Tavapadon tablet, Tavapadon [14C] suspension
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cerevel Therapeutics, LLC
Older Adults, Balance, Dance
Dance and Blood Flow Restriction as Balance Training for Older Women
Falls are one of the leading causes of hospitalization and mortality among older adults (aged 65+) in Canada. Falls result from postural instability following age-related declines in muscle strength which begin in the 5th decade…
- Conditions
- Older Adults, Balance, Dance, Blood Flow Restriction (BFR) Training Effects, Telehealth
- Trial name
- NCT07011784
- Testing
- Blood flow restriction in combination with dance classes, Dance classes alone
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Concordia University, Montreal
diabète de Type 1
Influence of Glycaemic Balance on the Ability of Apolipoprotein C1 to Inhibit Cholesteryl Ester Transfer Protein in Type-1 Diabetes Patients
In type-1 diabetes patients, bad cholesterol tends to accumulate because apoC1 function is slowed down. ApoC1 is a protein whose role is to diminish the activity of CETP, another protein that regulates cholesterol transfer in the…
- Trial name
- ApoC1 (NCT02816099)
- Testing
- Prise de sang
- Where
- 2 sites in France
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Temporomandibular Joint Disorders
Temporary Hydrostatic Splint Therapy and Its Effects on Occlusal Forces
The goal of this non-randomized controlled trial is to analyze and compare occlusal force distribution patterns using T-Scan III before and after hydrostatic splint therapy on both healthy subjects and subjects with…
- Trial name
- NCT05827263
- Testing
- T-Scan occlusal recording No. I, Usage of the hydrostatic appliance, T-Scan occlusal recording No. II
- Where
- Lithuania
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Healthy
Bioequivalence Study for Donepezil Hydrochloride Tablets 10 mg Under Fed Condition
This is an open label, balanced, randomized, two-treatment, two-period, two sequence, single dose, crossover, oral bioequivalence study.
- Trial name
- NCT01504516
- Testing
- Donepezil Hydrochloride, Aricept
- Where
- India
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy Volunteer
Mass Balance Study With MT-8554
This is a single-centre, open-label, mass balance study in healthy male subjects utilising a single oral dose of [14C] MT 8554.
- Trial name
- MT-8554 MB (NCT03381404)
- Testing
- [14C] MT-8554
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Tanabe Pharma America, Inc.
Stroke, Traumatic Brain Injury
Validation of an Obstacle Course Used in Patients With Muscle Tightness
This study is being conducted to compare healthy patients versus patients with muscle tightness in their leg(s) after an acquired brain injury using walking trials time, a balance test, and foot pressure data.
- Conditions
- Stroke, Traumatic Brain Injury, Multiple Sclerosis, Spasticity
- Trial name
- NCT00776048
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Cystic Fibrosis
Upper Extremity Exercise Capacity, Muscle Oxygenation, Balance in Patients With Cystic Fibrosis
The primary aim of the study is to evaluate upper extremity exercise capacity, muscle oxygenation, balance and physical activity level in patients with cystic fibrosis..
- Trial name
- NCT04803643
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Dizziness, Brain Injury
Vestibular Consequences of Blast-related Mild Traumatic Brain Injury (TBI)
The purpose of this project is to determine the effects of mild traumatic brain injury and blast exposure on the inner ear balance and central nervous systems.
- Trial name
- NCT01021137
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Healthy Volunteers, Low Back Pain
Effects of Blood Flow Restriction Exercises on Lumbar Muscle Endurance and Balance in Healthy Young Adults
This study aims to examine the effects of blood flow restriction (BFR) exercises on back muscle endurance and balance in healthy young adults.
- Conditions
- Healthy Volunteers, Low Back Pain, Postural Balance, Muscle Fatigue
- Trial name
- BFR-LUMBEX (NCT07182812)
- Testing
- Blood Flow Restriction Sit-to-Stand Exercise, Sit-to-Stand Exercise without Blood Flow Restriction
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Guler
Ankle Sprains, Ankle Injuries
Effect of Chronic Ankle Instability on Core Stabilization, Dynamic Balance and Agility
Ankle sprains are the most common injury in basketball, especially involving repetitive maneuvers such as acceleration, deceleration, jumping, and landing.
- Conditions
- Ankle Sprains, Ankle Injuries, Chronic Ankle Instability
- Trial name
- NCT05441319
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Chronotype
Investigation of the Effects of Chronotype Differences on Balance and Muscle Strength in Young Adults
The aim of this study is to investigate the effects of chronotype differences on balance and muscle strength in young adults. Chronotypes of all participants will be determined using the Morningness-Eveningness Questionnaire.
- Trial name
- Chronotype (NCT06949371)
- Testing
- Morning chronotype, Evening chronotype
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Obesity, Childhood
Food Genetics Behavior Study
A genetic risk for obesity does not always translate to the development of obesity among children, which points to the presence of risk-modifying factors that likely relate to energy balance behaviors as key behavioral drivers.
- Trial name
- FOODIE (NCT05783765)
- Testing
- Heightened Drive to Eat
- Where
- United States
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Postural Control
Effects of the Elastic Bandage on the Postural Balance of Young Women
Elastic Bandaging Therapy (BET) is a technique that consists of the application of elastic adhesive tape directed on a skin, and is used for pain reduction, improvement of flexibility, postural alignment.
- Trial name
- NCT03173911
- Testing
- Bandage
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universidade Norte do Paraná
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