Clinical trials: Bladder
Overactive Bladder
A Two-Part Study to Determine: Best Medication Formulation and Food Effect
This is a two-part study. Part 1 is designed to find the best modified release formulation of GW423753; Part 2 is designed to use the selected formulation(s) from Part 1 to find out if food affects the way the medication is…
- Trial name
- NCT00427596
- Testing
- Solabegron
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Overactive Bladder, Overactive Bladder Syndrome
Defining the Safety and Efficacy of POSterIor Tibial NeRve StimulatiON in Children
The purpose of this study is to find out if overactive bladder (OAB) can be safely treated by stimulating a nerve near the ankle. This procedure is called percutaneous tibial nerve stimulation (PTNS).
- Trial name
- POSITRON-C (NCT06769854)
- Testing
- Urgent PC
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chi Dang Hornik
Bladder Carcinoma, Breast Carcinoma
The Vanguard Study: Testing a New Way to Screen for Cancer
The Vanguard Study is a feasibility study to explore several aspects of evaluating multi-cancer detection (MCD) tests in a future definitive randomized controlled trial.
- Conditions
- Bladder Carcinoma, Breast Carcinoma, Colorectal Carcinoma, Esophageal Carcinoma
- Trial name
- NCT06995898
- Testing
- Biospecimen Collection, Device Usage, Electronic Health Record Review
- Where
- 45 sites in United States
- Volunteers
- 24,000 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Multiple Sclerosis, Neurogenic Bladder
Neurogenic Lower Urinary Tract Symptoms in Patients With Multiple Sclerosis
There is no consensus in the literature upon the neurourological diagnostic algorithm of the patients with multiple sclerosis (MS). The primary aim of the study is phenotyping the patients with MS.
- Trial name
- NCT05587101
- Testing
- Urodynamic Study (Filling cystometry and pressure-flow study), Questionnaires, Uroflowmetry
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Koç University
Overactive Bladder Syndrome
The Effect of Position on Urge Sensation in Volunteers and in Patients With Overactive Bladder Syndrome
Importance of the problem OAB is a common health problem. Milsom et al. [1] randomly selected a population from six European countries.
- Trial name
- NCT00821314
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Pediatric Urology
Diagnostic Performance of PIC Cystogram vs VCUG in Children
The goal of this interventional diagnostic clinical trial is to evaluate and compare the diagnostic effectiveness of PIC cystography and voiding cystourethrography (VCUG) for the detection of vesicoureteral reflux (VUR) in…
- Trial name
- NCT07334821
- Testing
- PIC cystography, VCUG
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tarik Emre Sener
Bladder Discomfort
Bladder Irrigation 0.05% Lidocaine Decreases Postoperative CRBD
Catheter-related bladder discomfort (CRBD) secondary to an indwelling urinary catheter is very distressing, and it may get worse in patients undergoing transurethral surgery for damage urethra by a surgical instrument as well as…
- Trial name
- NCT04133571
- Testing
- 0.05% Lidocaine
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Bladder Cancer, Glioma
Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer
The objective of this study is to assess two novel positron emission tomography (PET) radiotracers, [64Cu]CM500 and [68Ga]CM500, for Positron Emission Tomography-Magnetic Resonance Imaging (PET-MR) and Positron Emission…
- Conditions
- Bladder Cancer, Glioma, Glioblastoma (GBM), Breast Cancer
- Trial name
- NCT07781852
- Testing
- [64Cu]CM500, [68Ga]CM500, PET/MR
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lumina Pharmaceuticals Inc
Chronic Kidney Disease, Overactive Bladder
Urinary Function and Multimorbidity Risks: A Longitudinal Study in Beijing Community-Dwelling Elderly
This study focuses on Beijing community residents aged 60 and above, aiming to understand how urinary function (like bladder or kidney function) and multiple health problems (such as high blood pressure, diabetes) affect each…
- Conditions
- Chronic Kidney Disease, Overactive Bladder, Benign Prostatic Hyperplasia, Female Pelvic Floor Dysfunction
- Trial name
- UFMR-BE (NCT07357714)
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Gall Bladder Disease
Operating Room Outcomes After Resident Training on a Virtual Reality Simulator
The purpose of this study is to compare outcomes of patients undergoing laparoscopic cholecystectomy before and after a laparoscopic training curriculum was implemented.
- Trial name
- NCT00459472
- Testing
- laparoscopic training curriculum
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Columbia University
Pain
Trial of an Oral Sucrose Solution Versus Placebo in Children 1 to 3 Months Old Needing Bladder Catheterization
INTRODUCTION AND JUSTIFICATION The use of sucrose has been well studied for certain procedures in neonatal intensive care unit patients and in the newborn nursery settings, particularly for venous blood draws, capillary blood…
- Trial name
- NCT01544985
- Testing
- 88% sucrose po solution
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Prostatic Neoplasm, Urinary Bladder Neoplasm
The Effect of Prolonged Inspiratory Time on Gas Exchange During Robot-assisted Laparoscopic Surgery With Steep Trendelenburg Position : A Crossover Randomized Clinical Trial
Gas exchange disturbance frequently occurs in steep Trendelenburg position during robot-assisted laparoscopic prostatectomy or cystectomy.
- Trial name
- NCT02966535
- Testing
- Adjustment of Mechanical Ventilator Inspiratory to expiratory time ratio (1:2 to 1:1), Adjustment of Mechanical Ventilator Inspiratory to expiratory time ratio (1:1 to 1:2)
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Urinary Retention
Chronic Urinary Retention in Elderly Living in Homes for the Aged : Benefits of Bladder Scan Screening
The goal of this cross-sectional, multicentric and descriptive epidemiological study is to assess the prevalence of chronic urinary retention (CUR) in elderly living in residential care for dependent elderly people in order to…
- Trial name
- RUC EHPAD (NCT03828968)
- Testing
- bladder scan
- Where
- 5 sites in France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Schistosoma Haematobium
Possible Diagnostic Protein Markers in Schistosoma Related Bladder Diseases.
Schistosomiasis is the second most common parasitic infection affecting humans, endemic in the Middle East, especially Egypt (1), and in 42 African countries (2). There are 5 main species infecting humans: S. mansoni, S.
- Trial name
- NCT05941884
- Testing
- Immunohistochemistry staining,, microscopic examination of urine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assiut University
Urine Specimen Collection
The Effect of Bladder Stimulation Technique and Bathing Method on Urine Collection in Term Babies
Purpose of the Study: The aim of this study is to examine the effect of bladder stimulation technique and bathing method on urine collection in term infants hospitalized in the neonatal intensive care unit.
- Trial name
- NCT06188078
- Testing
- Control, The bladder stimulation technique, Bath
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Bladder Cancer
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascending Doses of APL-1501 Extended Release (ER) Capsules Compared to APL-1202 Immediate Release (IR) Tablets in Healthy Volunteers
This is an integrated Phase 1, single centre, 2-part, open-label, dose-escalation study conducted in healthy volunteers to assess the safety, tolerability, and PK of APL-1501 ER capsules in comparison to APL-1202 IR tablets.
- Trial name
- NCT06034015
- Testing
- APL-1202 and APL-1501 (Single ascending dose), APL-1202 and APL-1501 (Multiple Ascending dose)
- Where
- Australia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Jiangsu Yahong Meditech Co., Ltd aka Asieris
Uterine Prolapse, Bladder Diseases
Pelvic Floor Muscle Training (PFMT) in Treatment and Prevention of POP (POP Study)
Background: The pelvic floor muscles (PFM) are located inside the pelvis, surrounding the urethra, vagina and rectum. They provide structural support for the pelvic organs.
- Conditions
- Uterine Prolapse, Bladder Diseases, Cystocele, Rectocele
- Trial name
- NCT00271297
- Testing
- Pelvic floor muscle training
- Where
- Norway
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Overactive Bladder, Urge Urinary Incontinence
Safety and Applicability Study of a Novel Heat Flow Sensor Unit for Measuring Urinary Bladder Capacity
A novel sensor (a device named sensurine)was developed in the aim of real- time measurement of bladder volume. The sensurine device is a wearable, fully passive, non-invasive and compact heat flow sensor (patent pending) and…
- Conditions
- Overactive Bladder, Urge Urinary Incontinence, Enuresis, Self Clean Intermittent Catheterization
- Trial name
- NCT00437528
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Overactive Bladder
Hypnotherapy for Treatment of Overactive Bladder
The investigators purpose is to perform a pilot study evaluating the efficacy in hypnotherapy in treating women with Overactive Bladder Symptoms (urinary urgency symptoms and urinary frequency).
- Trial name
- NCT00793611
- Testing
- Behavioral therapy standard of care, hypnotherapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Healthy
Safety and Tolerability Study of the Taris Placebo System
The aim of this protocol is to evaluate the tolerability of the Taris placebo system for the development program and to provide key safety and tolerability data for the Taris platform.
- Trial name
- NCT01051336
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- TARIS Biomedical, Inc.