Clinical trials: CAD
Hypertension, Atherosclerosis
Age-Related Changes in Body Composition
Background: Advancing age is associated with greater risk of heart disease. High blood pressure and hardening of the arteries also have more complications with age.
- Trial name
- NCT01517113
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Cigarette Smoking, Coronary Heart Disease
Exercise and Coronary Heart Disease Risk Markers in Male Smokers and Non-Smokers
The present study will investigate the effect of acute exercise on fasting and postprandial risk markers for coronary heart disease (CHD) in healthy male cigarette smokers and non-smokers.
- Conditions
- Cigarette Smoking, Coronary Heart Disease, Cardiovascular Risk Factor, Insulin Resistance
- Trial name
- NCT03735186
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Coronary Artery Disease (CAD), Bypass, Cardiopulmonary
Multivessel Minimally Invasive Coronary Bypass Grafting as HYBRID Revascularization Versus Conventional Off-pump Coronary Artery Bypass Grafting
The MICRA-HYBRID trial is a prospective, multicenter, randomized controlled study comparing multivessel hybrid coronary revascularization (HCR) as minimally invasive arterial bypass grafting to left-sided coronary targets (LAD…
- Conditions
- Coronary Artery Disease (CAD), Bypass, Cardiopulmonary, Minimally Invasive Coronary Revascularization Surgery, Off-pump Coronary Artery Bypass
- Trial name
- MICRA-HYBRID (NCT07314138)
- Testing
- Multivessel Hybrid Coronary Revascularization, Off-pump coronary arterial bypass grafting (OPCAB)
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
Coronary Artery Disease, Coronary Heart Disease
Impact of Cardiac Rehabilitation on Patient Outcomes
Objective: This study aimed to retrospectively evaluate the impact of cardiac rehabilitation (CR) on functional capacity, depressive symptoms, health-related quality of life, and sleep quality in patients with heart disease.
- Trial name
- NCT07468955
- Testing
- Exercise Based Cardiac Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Coronary Artery Disease, Coronary Disease
The Effect of Hand Reflexology on Anxiety and Vital Signs With Angiography
This study was planned to determine the effect of hand reflexology on anxiety and vital signs in patients undergoing coronary angiography.
- Trial name
- NCT04956055
- Testing
- Reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Orthodontic Appliances, Fixed
Computer-aided Indirect Bonding Versus Traditional Direct Bonding of Brackets in Orthodontic Patients
Accurate bracket positioning is one of the keys for effective orthodontic treatment. Traditionally, orthodontic brackets are positioned one-by-one on the teeth of the patient, with the so-called direct bonding method.
- Trial name
- NCT04395625
- Testing
- Direct bonding of Orthodontic brackets, Indirect bonding of Orthodontic brackets
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Coronary Artery Disease (CAD), Obstructive Sleep Apnea (OSA)
Chemoreflex Control of Sympathetic Activity in Patients With Coronary Artery Disease
The investigators hypothesize that chemoreflex response of muscle sympathetic nerve activity (MSNA) during hypoxia and hypercapnia will be increased in coronary artery disease (CAD) patients and that the presence of obstructive…
- Trial name
- NCT02624297
- Testing
- Aerobic exercise training
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Coronary Artery Disease
Scaffold in Emilia Romagna and in the MAGIC Network
The prospective study will investigate the clinical performance and long-term safety of scaffold implantation in a real world regional setting. The protocol includes two different networks.
- Trial name
- SHERPA-MAGIC (NCT03327961)
- Testing
- scaffold
- Where
- 17 sites in Italy
- Volunteers
- 1,111 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
Coronary Artery Disease
Coenzyme Q10 in Relation to the Antioxidative Vitamins, Oxidative Stress and Inflammation in Coronary Artery Disease Patients During Statin Therapy
Cardiovascular disease (CVD) is the leading cause of Taiwan. American Heart Association (AHA) indicated that CVD patients with Statin therapy would decrease the recurrence of CVD.
- Trial name
- NCT01424761
- Testing
- Coenzyme Q10
- Where
- Taiwan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Diabetes Mellitus, Type 2 Diabetes
The Hong Kong Diabetes Biobank
Asia is in the midst of an epidemic of diabetes. Epidemiological figures suggest that there are more than 110 million people affected by diabetes in China, with a significant proportion of young adults already affected.
- Conditions
- Diabetes Mellitus, Type 2 Diabetes, Type 1 Diabetes, Diabetic Nephropathies
- Trial name
- HKDB (NCT05282680)
- Testing
- prospective observational study
- Where
- Hong Kong
- Volunteers
- 48,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery (CABG)
Examining the Effects of Video-Assisted Discharge Education After Coronary Artery Bypass Graft Surgery on Patient Satisfaction and Anxiety
This study was conducted to examine the effects of standard and individualized video-assisted discharge education on patient satisfaction and anxiety levels following Coronary Artery Bypass Graft (CABG) surgery.
- Conditions
- Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery (CABG), Postoperative Discharge Education
- Trial name
- NCT07528859
- Testing
- video discharge education, individual video discharge training, discharge education
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Coronary Artery Disease
Risk-guided Disease managEment Plan to prevEnt CAD in Patients Treated With Previous Cancer
REDEEM-CAD is a prospective multi-centre study of CAD risk evaluation and management in cancer survivors 40-70 years with chemotherapy or radiotherapy >5 years ago.
- Trial name
- REDEEM-CAD (NCT05366153)
- Testing
- Coronary CT
- Where
- 2 sites in Australia
- Volunteers
- 748 people, healthy volunteers welcome
- Sponsor
- Baker Heart and Diabetes Institute
Cardiovascular Disease, Coronary Heart Disease
Heart to Health: A Combined Lifestyle and Medication Intervention to Reduce Cardiovascular Disease (CVD) Risk
Cardiovascular disease (CVD), including heart disease and stroke, is the leading cause of death in the US. Every year, more than one million Americans have a heart attack, and nearly 800,000 have a stroke.
- Trial name
- NCT01245686
- Testing
- Lifestyle and medication intervention
- Where
- 5 sites in United States
- Volunteers
- 489 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Coronary Artery Disease
L-carnitine and Coenzyme Q10 in Relation to the Oxidative Stress, Antioxidant Enzymes Activities, Inflammation, and the Risk of Coronary Artery Disease
Cardiovascular disease (CVD) is the leading cause of Taiwan. L-carnitine (LC) and coenzyme Q10 is recognized as lipid soluble antioxidants.
- Trial name
- NCT01819701
- Testing
- LC-1000, LC-2000, Q10-150
- Where
- Taiwan
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Coronary Artery Disease (CAD)
A Study to Assess the Amount of Drug Levels in Blood and Safety of AZD5718 Formulations in Healthy Volunteers
The study is a randomized, single-dose, open-label, combined 2x2 dose and 3x3 dose crossover design in fixed sequence. In this study, the relative bioavailability of different formulations of AZD5718 will be assessed in healthy…
- Trial name
- NCT04210388
- Testing
- AZD5718 tablet, Formulation A, AZD5718 tablet, Formulation B, AZD5718 tablet, Formulation C
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Metabolic Syndrome, Coronary Artery Disease
A Case Control Study of Resveratrol Effects in Coronary Artery Disease Patients With Metabolic Syndrome
The aim of this study is to explore the role of Canonical β-catenin/Wnt and forkhead box O (FOXO) pathways by means of investigating their target genes in coronary artery disease (CAD) pathogenesis and to examine the effects of…
- Trial name
- NCT02137421
- Testing
- Resveratrol (3, 4´, 5 trihydroxystilbene)
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Lung Cancer, Lung Diseases
A Clinical Study of LUNG-CT CAD Decision Support
This product is a computer-aided detection software designed to assist clinicians in detecting lung nodules in chest computer tomography.
- Trial name
- NCT05230563
- Testing
- Ti-LUNG
- Where
- Taiwan
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- TaiHao Medical Inc.
Dental Pulp Diseases
Survival of Root Canal Treated Teeth Restored With Ceramic Onlays
Advances in digital dentistry coupled with increased demand for aesthetic restorations have led to developments in CAD CAM( Computer Aided Design and Computer Aided manufacturing)systems for manufacturing tooth restorations.
- Trial name
- NCT03378778
- Testing
- Root canal treatment
- Where
- United Kingdom
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- King's College London
Lung Cancer
Chest Imaging, Breath, and Biomarkers in a Screening Trial
The investigators would like to see if lung cancer screening with chest x-rays,computer aided detection (CAD)and a lose dose CT scan can detect lung cancer in early stages when it is more responsive to treatment.
- Trial name
- NCT01663155
- Testing
- chest x-ray with or without CAD, lose dose CT scan
- Where
- United States
- Volunteers
- 1,424 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Coronary Artery Disease
Virtual Coronary Intervention and Non-invasive Fractional Flow Reserve (FFR)
The investigators examined the feasibility of treatment planning using virtual coronary revascularization and fractional flow reserve (FFR) CT before the invasive procedures.
- Trial name
- NCT01478100
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital