Clinical trials: CPR, open to volunteers
Cardiopulmonary Arrest, Pediatric ALL
Impact of a mHealth Supportive Tool on Cardiopulmonary Resuscitation' Situational Awareness
This study will be a prospective, single-center, randomized controlled trial in a tertiary pediatric emergency department with two parallel groups of voluntary pediatric physicians and nurses.
- Conditions
- Cardiopulmonary Arrest, Pediatric ALL, Resuscitation
- Trial name
- InterFACE (NCT04464603)
- Testing
- InterFACE (mHealth tool), Conventional methods
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Hypertension Disorders in Pregnancy
Cerebroplacental Ratio (CPR) and Amniotic-Umbilical-to-Cerebral Ratio (AUCR), in in Women With Hypertensive Disorders of Pregnancy.
The primary aim of this study is to evaluate the predictive value of the Amniotic-Umbilical-to-Cerebral Ratio (AUCR) in predicting composite adverse perinatal outcomes in women with hypertensive disorders of pregnancy and to…
- Trial name
- CPR_AUCR2026 (NCT07795320)
- Volunteers
- 130 people
- Sponsor
- Assiut University
Cardiac Arrest, Out-Of-Hospital
Gathering Evidence on Best Practices for Lay Rescuer CPR Training
The goal of this prospective trial is to compare CPR skill and attitudes in lay rescuers. The main question[s] it aims to answer are: What is the optimal training timing, duration, and frequency for lay rescuers that leads to CPR…
- Trial name
- NCT05908500
- Testing
- CPR Training, CPR Manikin Type
- Where
- United States
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Reno
Cardiac Arrest, Out-Of-Hospital
Prehospital ECPR in Moravia Silesia Region
Cardiopulmonary resuscitation (CPR) for out-of-hospital cardiac arrest (OHCA) in specific cases could be improved by Extracorporeal membrane oxygenation (ECMO; ECPR).
- Trial name
- 01-Pain (NCT07041086)
- Testing
- Extracorporeal membrane oxygenation (ECMO)
- Where
- 2 sites in Czechia
- Volunteers
- 100 people
- Sponsor
- University Hospital Ostrava
Cardiac Arrest (CA)
Adapted Cardiopulmonary Resuscitation Study
The goal of this controlled single centre RCT is to compare frequency rates concerning return of spontaneous circulation (ROSC) in prehospital cardiac arrest.
- Trial name
- NCT07754656
- Testing
- aCPR algorithm, ERC ALS 2025
- Where
- Austria
- Volunteers
- 216 people
- Sponsor
- Johannes Kepler University of Linz
Choking in Infants, Cardiopulmonary Resuscitation (CPR)
Parental Knowledge of First Aid for Choking and Cardiopulmonary Resuscitation in Infants Under One Year of Age
This study aims to assess the knowledge of parents regarding first aid for choking and cardiopulmonary resuscitation (CPR) in infants under one year of age.
- Conditions
- Choking in Infants, Cardiopulmonary Resuscitation (CPR), First Aid Training, Parental Knowledg
- Trial name
- NCT06976463
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Andrzej Frycz Modrzewski Krakow University
Cardiac Arrest (CA), In-Hospital Cardiac Arrest
The Ventilation During In-hospital Cardiac Arrest Study
The goal of this prospective observational study is to learn how ventilation quality parameters during cardiopulmonary resuscitation (CPR) are associated with short-term survival following in-hospital cardiac arrest of adult…
- Conditions
- Cardiac Arrest (CA), In-Hospital Cardiac Arrest, Heart Arrest
- Trial name
- VENT-IHCA (NCT06809309)
- Testing
- Positive pressure ventilation during cardiopulmonary resuscitation
- Where
- 11 sites in Denmark, Norway
- Volunteers
- 900 people
- Sponsor
- University of Aarhus
Cardiac Arrest
Target-directed Management of Cerebral Oxygenation in Patients After Receiving ECPR
Neurological injury remains an important cause of morbidity and mortality in patients with ECPR. At present, the results of three prospective randomized controlled studies on ECPR are inconsistent, and it is inconclusive whether…
- Trial name
- TDMCO-ECPR (NCT06711016)
- Testing
- if rSO2 < 58%, if rSO2 58%-68%, rSO2>68%
- Where
- 2 sites in China
- Volunteers
- 654 people
- Sponsor
- Qilu Hospital of Shandong University
Low-Dose High-Frequency CPR Training
Low-Dose, High-Frequency CPR Training in Pediatric Emergency Nurses
Life-threatening conditions such as respiratory failure, shock, and cardiac arrest require rapid recognition and timely intervention in pediatric emergency settings.
- Trial name
- LDHF CPR Peds (NCT07508085)
- Testing
- Low-Dose High-Frequency CPR Training, Massed CPR Training
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara University
Cardiopulmonary Resuscitation (CPR), Basic Life Support Training Course
Evaluation of Mixed Reality Cardiopulmonary Resuscitation Training
<Study Design> This study is a cluster-randomized, stratified, non-inferiority trial designed to evaluate the feasibility, efficacy, and educational effectiveness of HEROS 4.0, a mixed-reality (MR)-based cardiopulmonary…
- Conditions
- Cardiopulmonary Resuscitation (CPR), Basic Life Support Training Course, Cardiac Arrest (CA)
- Trial name
- HEROS 4 (NCT07363772)
- Testing
- HEROS 4.0, Conventional CPR training
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Cardiac Arrest, Extracorporeal Membrane Oxygenation
Predictors for Survival and Good Neurological Outcome in E-CPR and Non CPR Treated Patients
In ECPR, where CPR times often range from 30 to 120 minutes, only patients with good circulation during CPR survive, while non-survivors commonly suffer from anoxic brain injury.
- Conditions
- Cardiac Arrest, Extracorporeal Membrane Oxygenation, Hypoxia-Ischemia, Brain
- Trial name
- NCT04198792
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 700 people
- Sponsor
- Sahlgrenska University Hospital
Cardiac Death, Cardiac Arrest
Quality of Cardiopulmonary Resuscitation Pre- and Intra Hospital
The survival after intrahospital cardiac arrest has been reported to 15%. In Norway this varies between 16 and 23%.). Many factors are associated with survival after cardiac arrest, both intra- and prehospital.
- Conditions
- Cardiac Death, Cardiac Arrest, Cardiac Arrhythmia, Cardiac Disease
- Trial name
- NCT04295291
- Volunteers
- 300 people
- Sponsor
- Ostfold University College
Out-of-hospital Cardiac Arrest (OHCA), Cardiac Arrest (CA)
the Effectiveness of Continuous Compression-synchronous Ventilation (Bio-CPR)
Bio-CPR is an innovative new mechanical resuscitation model proposed by our research group. A multi-center RCT study was established to comprehensively evaluate the efficacy of this model and the current standard CPR protocol…
- Conditions
- Out-of-hospital Cardiac Arrest (OHCA), Cardiac Arrest (CA), CPR, ACLS
- Trial name
- Bio-CPR (NCT07258823)
- Testing
- CPR
- Volunteers
- 408 people
- Sponsor
- Guangdong Provincial People's Hospital
Cardiac Arrest, Cardiopulmonary Resuscitation
Generative AI and Gamified Simulation-Based Train-the-Trainer Basic Life Support Training for High School Teachers in Vietnam
The goal of this randomized controlled trial is to learn whether adding generative artificial intelligence (AI) feedback, gamified practice and a structured Train-the-Trainer component to a one-day simulation-based Basic Life…
- Trial name
- NCT07898891
- Testing
- Generative AI and Gamified Simulation-Based Train-the-Trainer BLS Programme, Conventional Instructor-Led Simulation-Based BLS Training
- Where
- 2 sites in Thailand, Vietnam
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Eastern International University
Cardiac Arrest, Post-cardiac Arrest Care
Neuroprotection Bundles For Comatose Survivors Following Cardiac Arrest
The investigators designed LAPTOPS to determine the effectiveness of a goal-directed neuroprotection bundles of active management including body temperature,PaCO2,PaO2,position,Blood glucose ,blood sodium,Blood pressure and…
- Trial name
- LAPTOPS (NCT06992843)
- Testing
- Goal-directed care bundle for neuroprotection, Usual Care
- Where
- China
- Volunteers
- 1,008 people
- Sponsor
- Xiangya Hospital of Central South University
Cardiac Arrest (CA)
Effectiveness of a Communication Training Program in Improving the Handling of Calls for Suspected Cardiac Arrest at SAMU-Centre 15.
Each year, France's emergency response services-the SAMU (15) and the fire department (18)-handle 31 million and 19 million calls, respectively.
- Trial name
- COM-ARM (NCT07776990)
- Testing
- Multifaceted intervention including 4 components
- Where
- 10 sites in France
- Volunteers
- 987 people
- Sponsor
- University Hospital, Grenoble
Cardiopulmonary Resuscitation
Evaluating Length and Depth Estimation Accuracy of Laypersons and Health-Care Providers
The objective of the study is to measure accurateness of length and depth estimation of laypersons and health-care providers.
- Trial name
- NCT06552299
- Testing
- Laypersons, Health-Care Providers
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Cardiac Arrest (CA), Cardiac Arrest With Successful Resuscitation
A Study on the Impact of a New Canton-Wide First Responder System in Zug, Switzerland, on Survival After Adult Cardiac Arrest-Examining Early Life-Saving Organized Help, Fast Defibrillation, and Improved Outcomes for Out of Hospital Cardiac Arrest
REVIVE Zug: Improving Emergency Response for Out-of-Hospital Cardiac Arrest Out-of-hospital cardiac arrest (OHCA) represents one of the most time-critical medical emergencies, where rapid recognition and immediate intervention…
- Conditions
- Cardiac Arrest (CA), Cardiac Arrest With Successful Resuscitation, Resuscitation, Emergency Medical Services
- Trial name
- REVIVE Zug (NCT07323667)
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- Felix Brinkmann
Cost Analysis, Length of ICU Stay
An Artificial Intelligence Model for Intensive Care Length of Stay, Neurological Outcome and Costs Estimation After Cardiopulmonary Resuscitation: a Cohort Study.
The study aims to overview patients registered to Bezmialem Vakıf University Hospital Intensive Care Unit after successive cardiac arrest resuscitation from October 2010 to September 2025.
- Conditions
- Cost Analysis, Length of ICU Stay, Neurological Outcome
- Trial name
- NCT07210866
- Testing
- no physical or medical interventions
- Volunteers
- 5,000 people
- Sponsor
- Bezmialem Vakif University
Intraoperative Cardiac Arrest
Cardiopulmonary Resuscitation in Operating Room
In the last ten years patient safety during routine surgical interventions has increased; however as there is an increase in the number of specialized surgical interventions and high risk patients like elderly and emergency…
- Trial name
- CPR (NCT02884271)
- Testing
- cardiopulmonary resuscitation
- Where
- Turkey (Türkiye)
- Volunteers
- 7 people
- Sponsor
- Dokuz Eylul University