Clinical trials: Caffeine
Caffeine
Effects of Caffeine in Hydration and Energy Metabolism
The main purposes of this randomized cross-over trial are to characterize and compare the effects of a moderate dose of caffeine intake in healthy physically active males on hydration and energy metabolism specifically: 1.
- Trial name
- NCT01477294
- Testing
- Caffeine
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Technical University of Lisbon
Energy, Focus
Effect of Different Dosages of Paraxanthine, the Major Caffeine Metabolite, on Energy and Focus
Research has shown that acute ingestion of Paraxanthine (1,7-dimethylxanthine, PXN) can enhance various markers of focus, including memory, reaction time, and attention in healthy adults.
- Conditions
- Energy, Focus, Caffeine Withdrawal
- Trial name
- NCT06117280
- Testing
- Paraxanthine 200 mg, Paraxanthine 300 mg
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Iovate Health Sciences International Inc
Pharmacokinetics of Repaglinide, Pharmacokinetics of Caffeine
A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Repaglinide and Caffeine
The purpose of this study is to assess the effect of multiple doses of isavuconazole on the pharmacokinetics of Repaglinide and possible metabolites after single dose administration.
- Conditions
- Pharmacokinetics of Repaglinide, Pharmacokinetics of Caffeine, Healthy Subjects
- Trial name
- NCT02128321
- Testing
- Isavuconazole, Repaglinide, Caffeine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.
Dehydration, Dehydration Related to Exercise
The Impact of a Caffeinated Sports Drink on Performance
Caffeine is known to enhance physical and mental performance, but few beverages combine caffeine with electrolytes and carbohydrates to enhance exercise performance.
- Trial name
- NRG (NCT06721793)
- Testing
- carbohydrate electrolyte drink, no-sugar electrolyte drink, Caffeinated Carbohydrate and electrolyte drink
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Substrate Oxidation, Energy Expenditure
Exercise-Induced Rates of Fat Oxidation with and Without Ingestion of a Caffeine-Based Energy Drink
The purpose of this study is to evaluate acute changes in rates of fat oxidation during exercise with and without the ingestion of a caffeine-based energy drink.
- Conditions
- Substrate Oxidation, Energy Expenditure, Reaction Time, Cognition
- Trial name
- EDX (NCT06308731)
- Testing
- Caffeine-Based Energy Drink
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Smoking Behaviors
Effect of Oral pH Changes on Smoking Desire
Nicotine is a psychoactive substance and its effect is demonstrated by neuronal nicotinic-acetylcholine receptors excreted in the brain and periphery.
- Trial name
- NCT04032236
- Testing
- caffeine
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Caffeine
Effect of Caffeine on Myocardial Oxygenation
The purpose of this study is to investigate the impact of caffeine on myocardial oxygenation and other cardiovascular magnetic resonance parameters in healthy controls.
- Trial name
- Coffee-O2 (NCT04585854)
- Testing
- Caffeine
- Where
- Switzerland
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Stress, Menopause
Radicle Revive 24: A Study of Health and Wellness Products on Hormonal Health and Associated Health Outcomes in Women With Peri-Menopausal Health Issues
A Randomized, Double-Blind, Placebo-Controlled, Direct-to-Consumer Trial Assessing the Impact of Health and Wellness Products on Hormonal Health and Associated Health Outcomes in Women with Peri-Menopausal Health Issues
- Conditions
- Stress, Menopause, Fatigue, Sleep
- Trial name
- NCT07117994
- Testing
- Radicle Revive Active Study Product 1
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Caffeine, Placebo - Control
Effects of Caffeine Ingestion on Morning Cognitive and 4-km Time Trial Performance in Males
Athletes often compete in the morning when they are biologically weaker; normally in competition heats or quarterfinals to qualify for the finals scheduled in the evening.
- Conditions
- Caffeine, Placebo - Control, No Pill
- Trial name
- NCT07469852
- Testing
- Caffeine (300 mg), No Pill
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Healthy Adults; Hematopoietic System; Caffeine
Impact of Chronic and Acute Caffeine Intake on the Hematopoietic System
This study investigates how caffeine intake affects blood stem and progenitor cells in healthy adults. The trial will compare people who regularly consume caffeine with those who consume very little or none.
- Trial name
- CaffeineHSC (NCT07193264)
- Testing
- Caffeine (200 mg)
- Where
- 2 sites in Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jasmin Rettkowski
Athletic Performance, Cognitive Performance
Effects of Different Doses of Caffeine on Physical and Cognitive Performance in Female Handball Players
This study investigates how different doses of caffeine affect physical and cognitive performance in female handball players. Caffeine is widely used as a performance-enhancing substance, but its effects may vary depending on the…
- Conditions
- Athletic Performance, Cognitive Performance, Healthy Adult Females
- Trial name
- NCT07562256
- Testing
- Caffeine 3 mg/kg, Caffeine 6 mg/kg
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sinop University
Healthy, Caffeine
Effects of Caffeine on Reinforcement Learning in Healthy Adults Using PET/MRI
This research study aims to determine whether and how caffeine intake affects learning process through reward feedback compared to placebo.
- Conditions
- Healthy, Caffeine, Adenosine, Dopamine D2/3 Receptor Availability
- Trial name
- Caffeine-RAC (NCT06763172)
- Testing
- Caffeine (200 mg)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hsiao-Ying Wey
Withdrawal Symptoms
The Potentially Addictive Properties of Soda: A Feasibility Study
The purpose of this study to investigate the addictive properties of soda and other sugar sweetened beverages (SBBs) in teenagers aged 13-18 years.
- Trial name
- NCT02044757
- Testing
- SSB withdrawal
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Neurobehavioral Manifestations, Drug Related Sleep Disturbance
Acute and Residual Effects of Caffeinated Beer
The aim of this study is to develop information about the acute and residual effects of a new product being targeted to young adults.
- Conditions
- Neurobehavioral Manifestations, Drug Related Sleep Disturbance, Alcohol Intoxication
- Trial name
- NCT00515294
- Testing
- Caffeinated Alcoholic Beer, Non-Caffeinated Alcoholic Beer, Caffeinated Non-Alcoholic Beer
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Boston University
Energy Metabolism
Acute Effects of Caffeine on Mitochondrial Function in Peripheral Blood Mononuclear Cells
This randomized, double-blind, placebo-controlled crossover study will evaluate the acute effects of caffeine consumption on substrate utilization, resting energy metabolism, and mitochondrial function in peripheral blood…
- Trial name
- MITOCAFFEINE (NCT07873047)
- Testing
- Caffeine (5 mg/kg)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Caffeine
Caffeine Supplementation, Resistance Training and Blood Antioxidant Status
The purpose of this study is to verify the effect of acute caffeine intake on resistance training volume and blood antioxidant status, in a randomised, double-blind, placebo-controlled crossover trial.
- Trial name
- NCT05230303
- Testing
- Caffeine supplementation
- Where
- Poland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Healthy Elderly Citizens
The Effect of Caffeine in Elderly Citizens
The study investigated the effect of caffeine on physical performance in healthy citizens aged over 70 years. The main hypothesis was that 6 mg/kg caffeine would improve cycling endurance at 65% of expected maximal heart rate.
- Trial name
- NCT00117520
- Testing
- Caffeine
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Herning Hospital
Dietary Supplements, Caffeine
Effect of Acute Caffeine and Beetroot Juice Intake on Strength, Power, and Muscular Endurance
Introduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine and beetroot juice intake on sports performance.
- Conditions
- Dietary Supplements, Caffeine, Nitrates, Sports Performance
- Trial name
- CAF+BJ (NCT06596395)
- Testing
- Acute caffeine and beetroot juice, Acute caffeine, Acute beetroot juice
- Where
- Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Healthy
Effects of Repeated Doses of Foliglurax on Drug Metabolizing Enzymes in Healthy Subjects
The purpose of this study is to help determine which types of drugs that may interact with foliglurax
- Trial name
- NCT04275115
- Testing
- Drug Cocktail, Foliglurax, midazolam iv
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Cognitive Performance, Attention
Effects of Caffeine on Chess Performance and Cognitive Function in Professional Chess Players
This study will examine whether caffeine improves cognitive and competitive performance in professional chess players during tournament-style games.
- Conditions
- Cognitive Performance, Attention, Reaction Time, Caffeine
- Trial name
- GRANDMASTER (NCT07641335)
- Testing
- Caffeinated Coffee
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- St. Louis University