Clinical trials: Calculi, Renal
Kidney Stone
Effect of Weight Loss on Urinary Oxalate Excretion in Obese Calcium Oxalate Kidney Stone Formers
This protocol seeks to determine if weight reduction with the Optifast VLCD program leads to reduced contribution of endogenous oxalate synthesis and dietary oxalate absorption to the urinary oxalate pool in obese calcium oxalate…
- Trial name
- NCT04633811
- Testing
- Low Oxalate Diet before Weight Loss, Oral load of oxalate and sucralose before Weight Loss, Optifast VLCD Program
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Alabama at Birmingham
Urolithiasis
High Supracostal Versus Subcostal Puncture in Adult PCNL
as the supra eleventh puncture PCNL is not well investigated in the literature we will conduct that randomised trial in comparison to the subcostal one
- Trial name
- NCT06350045
- Testing
- PCNL
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Assiut University
Kidney Calculi (or Renal Calculi / Nephrolithiasis), Supine Mini Percutaneous Nephrolithotomy
Supine vs. Prone Mini-PCNL in Children
Percutaneous nephrolithotomy (PCNL) is an established intervention for large or ESWL-resistant renal stones in pediatric populations.
- Conditions
- Kidney Calculi (or Renal Calculi / Nephrolithiasis), Supine Mini Percutaneous Nephrolithotomy, Prone Mini Percutaneous Nephrolithotomy
- Trial name
- SUPRO-PED (NCT07887945)
- Testing
- Group A, Group B
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Fayoum University Hospital
Nephrolithiasis
Hydrochlorothiazide for Kidney Stone Recurrence Prevention
The investigators plan to assess the efficacy of standard and low dose HCTZ treatment in the recurrence prevention of calcium-containing kidney stones.
- Trial name
- NOSTONE (NCT03057431)
- Testing
- 12.5 mg hydrochlorothiazide, 25.0 mg hydrochlorothiazide, 50.0 mg hydrochlorothiazide
- Where
- 12 sites in Switzerland
- Volunteers
- 416 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Nephrolithiasis, Kidney Stone
Mini-PNCL vs fURS in Management of Nephrolithiasis
The prevalence of nephrolithiasis is increasing over the last two decades, and kidney stones is a recurrent disorder, with lifetime recurrence risks reported to be as high as 50%.
- Trial name
- NCT04389853
- Testing
- Flexible ureteroscopy, Mini-percutaneous nephrolithotomy
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Thunder Bay Regional Health Research Institute
Kidney Stones
Struvite Stones Antibiotic Study
The aim of this research is to determine an effective antibiotic regimen following definitive surgical therapy of kidney stones caused by bacterial infection (struvite stones).
- Trial name
- NCT02375295
- Testing
- ciprofloxacin, cotrimoxazole-trimethoprim, macrodantin
- Where
- 12 sites in United States, Canada
- Volunteers
- 28 people
- Sponsor
- University of British Columbia
Nephrolithiasis
Evaluation of a Nonopioid Recovery Pathway Following Surgery for Kidney Stones
Evaluation of a nonopioid recovery pathway after percutaneous nephrolithotomy is a pragmatic pilot study that will apply the knowledge and experience gained with development of an outpatient opioid reduction protocol to…
- Trial name
- NCT04597619
- Testing
- Novel Nonopioid Pathway
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Miriam Hospital
Urolithiasis, Kidney Stone
Comparing Efficacy and Complication Between Prone Versus Prone-Flexed Position for Percutaneous Nephrolithotomy (PCNL)
Comparing Efficacy and Complication Between Prone Versus Prone-Flexed Position For Percutaneous Nephrolithotomy (PCNL)
- Conditions
- Urolithiasis, Kidney Stone, Complication
- Trial name
- NCT06624306
- Testing
- Prone PNL, Prone-flexed PNL
- Where
- Egypt
- Volunteers
- 85 people
- Sponsor
- Fayoum University Hospital
Renal Stone
Changes Post Percutaneous Nephrolithotomy
Using color doppler U/S, Abdominal U/S and radioisotope to evaluate changes of renal morphology, function and doppler parameters post Percutaneous nephrolithotomy
- Trial name
- KUB (NCT06185387)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Kidney Disease
A Prospective Comparison Between Ureteral Stent and Nephrostomy Tube for an Urgent Drainage of Obstructed Kidney
Kidney obstruction might be caused by a stone in the urinary tract. In case of accompanying fever or renal failure, an urgent drainage might be needed. This can be done either by placing an ureteral stent or a nephrotomy tube.
- Trial name
- JJVsPCN08 (NCT00739284)
- Testing
- nephrostomy tube and ureteral stent
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rabin Medical Center
Urolithiasis, Nephrolithiasis
Effect of Furosemide on ESWL Outcomes for Renal and Ureteral Calculi
The minimally-invasive extracorporeal shockwave lithotripsy (ESWL) procedure is generally considered the best first-line treatment option for most adults and children with nephrolithiasis, especially when the calculi are smaller…
- Conditions
- Urolithiasis, Nephrolithiasis, Urinary Calculi, Ureterolithiasis
- Trial name
- NCT05270421
- Testing
- Furosemide 40 mg, Conventional Treatment
- Where
- Iran
- Volunteers
- 500 people
- Sponsor
- Shiraz University of Medical Sciences
Kidney Stone
Robotic-assisted Percutaneous Access
This is a first-in-man (FIM) study to show feasibility and safety profile of the newly developed robotic device for percutaneous access in PCNL surgery.
- Trial name
- NCT04435132
- Testing
- PCL under fluoroscopy with the aid of the robotic device
- Where
- Malaysia
- Volunteers
- 5 people
- Sponsor
- NDR Medical Technology Pte Ltd
Urolithiasis, Kidney Stones
Assessment of Fluoroscopy Times With Surgeon Versus Technologist Control
This is a prospective randomized trial to study the effect of assigning the control of the fluoroscopic x-ray activation to the surgeon as compared to the radiation technologist.
- Trial name
- NCT02224287
- Testing
- Technologist control of fluoroscopy, Surgeon control of fluoroscopy
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Boston Children's Hospital
Kidney Stones
Feasibility of Radiation-Free Percutaneus Nephrolithotomy for Kidney Stones
The goal of this observational study is to investigate the feasibility of ultrasound-guided percutaneus nephrolithotomy in patients with kidney stones.
- Trial name
- PCNL (NCT06922006)
- Testing
- Percutaneus nephrolithotomy (PCNL)
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of California, San Diego
Renal Calculi
The Influence of SMP on Renal Pelvic Pressure In Vivo
Percutaneous nephrolithotomy (PCNL) is a well-established treatment modality for renal stones. It offers a high stone free rates and less invasive than open surgery.
- Trial name
- NCT02760134
- Testing
- Super-Mini Percutaneous Nephrolithotomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Ureterolithiasis, Nephrolithiasis
Prospective Comparison Between Different Laser Settings for Ureteral \ Kidney Stones Treatment During Ureteroscopy
A prospective study comparing different laser settings used for stone fragmentation during ureteroscopy
- Trial name
- NCT02279927
- Testing
- Ureteroscopy
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Carmel Medical Center
Kidney Stone
Treatment Optimization and Nephrolithiasis Recurrence Prevention With Interdisciplinary Care
Nearly 10% of the Belgian population suffer from kidney stone disease. Recent reviews reported that kidney stones represent an underestimated risk factor for further kidney function deterioration.
- Trial name
- NCT06367894
- Where
- Belgium
- Volunteers
- 164 people
- Sponsor
- Agnieszka Pozdzik
PNL, Stone, Kidney
Three Dimensional Virtual Reconstruction (3D) in Percutaneous Nephrolithotomy
The aim of our study is to investigate the effect of 3D imaging technique on the PCNL learning curve in specialist training.
- Trial name
- NCT06797466
- Testing
- 3D imaging technique on the PCNL
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Adiyaman University
Renal Calculi, Postoperative Pain
Efficacy of Liposomal Bupivacaine for Pain Control After Percutaneous Nephrostolithotomy
Percutaneous nephrostolithotomy (PCNL) is a common endoscopic procedure performed for upper urinary tract calculus disease. Despite being minimally invasive, it is associated with significant postoperative pain, often…
- Trial name
- NCT03043027
- Testing
- liposomal bupivicaine, Bupivacaine, Saline Solution
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Nephrolithiasis
Intrarenal Pressure in Suctioning vs. Non-suctioning Sheaths
Interest in monitoring intrarenal pressure (IRP) during flexible ureteroscopy (fURS) has grown, especially due to its potential association with improved postoperative efficiency and safety.
- Trial name
- NCT07619456
- Testing
- Suctioning-UAS, Non-suctioning-UAS
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Icahn School of Medicine at Mount Sinai