Clinical trials: Cardiac Ischemia
Coronary Artery Disease, Drug-eluting Stent
A Prospective Multicenter Post Approval Study to Evaluate the Long-term Safety and Efficacy of the Resolute Integrity in the Japanese All-comers Patients With Coronary Artery Disease (PROPEL)
This is a prospective, multicenter, historical controlled study. The present clinical study will measure non-inferiority of 12 month TLF rate compared to historical control.The selected historical control is the Xience V arm from…
- Trial name
- NCT01808391
- Where
- Japan
- Volunteers
- 1,204 people, healthy volunteers welcome
- Sponsor
- Associations for Establishment of Evidence in Interventions
Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery (CABG)
Examining the Effects of Video-Assisted Discharge Education After Coronary Artery Bypass Graft Surgery on Patient Satisfaction and Anxiety
This study was conducted to examine the effects of standard and individualized video-assisted discharge education on patient satisfaction and anxiety levels following Coronary Artery Bypass Graft (CABG) surgery.
- Conditions
- Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery (CABG), Postoperative Discharge Education
- Trial name
- NCT07528859
- Testing
- video discharge education, individual video discharge training, discharge education
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Cardiovascular Diseases, Stroke
Prediction of Primary Cardiovascular Events Using the Multimarker Approach
The study of biochemical risk factors for cardiovascular diseases is important not only for analysis, but also for preventive measures, given that changes in the level of biomarkers can be detected before the first clinical…
- Conditions
- Cardiovascular Diseases, Stroke, Myocardial Infarction, Death
- Trial name
- NCT05704569
- Testing
- measurement of multiple biomarkers
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Karaganda Medical University
Coronary Artery Disease, Diabetes Mellitus Type 2
Effects of Hyperglycemia on Myocardial Perfusion in Humans With and Without Type 2 Diabetes
The overall goal of this proposal is to determine the effects of acute hyperglycemia and its modulation by Glucagon-like Peptide-1 (GLP-1) on myocardial perfusion in type 2 diabetes (DM).
- Trial name
- GLP-1 (NCT01021865)
- Testing
- Glucagon-Like-Peptide-1/Regadenoson/Perflutren Lipid Microsphere
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Type2 Diabetes, Coronary Artery Disease
Dietary Analyses in the Nurses' Health Study, Nurses' Health Study II, and Health Professionals Follow-Up Study
To determine the relationships of a variety of nutrients, foods, and dietary patterns with the subsequent risk of developing type 2 diabetes, cardiovascular disease, and mortality in US men and women.
- Conditions
- Type2 Diabetes, Coronary Artery Disease, Morality, Stroke
- Trial name
- Diet (NCT03366532)
- Testing
- Dietary assessments
- Volunteers
- 289,900 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Coronary Artery Disease
Impact of Breathing Maneuvers on the Oxygenation Supply of the Heart Assessed With MRI in Patients With Coronary Artery Disease
Patients with an impaired blood supply of the heart routinely receive oxygen in order to improve or preserve the oxygen supply of the heart muscle in acute cardiac care.
- Trial name
- CADOS-CMR (NCT02233634)
- Testing
- Oxygen, Hyperventilation Breath-hold (HVBH), HVBH with Oxygen
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Metabolic Syndrome, Coronary Artery Disease
A Case Control Study of Resveratrol Effects in Coronary Artery Disease Patients With Metabolic Syndrome
The aim of this study is to explore the role of Canonical β-catenin/Wnt and forkhead box O (FOXO) pathways by means of investigating their target genes in coronary artery disease (CAD) pathogenesis and to examine the effects of…
- Trial name
- NCT02137421
- Testing
- Resveratrol (3, 4´, 5 trihydroxystilbene)
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Coronary Heart Disease, Cardiovascular Risk Factor
Individual Variability of Coronary Heart Disease Risk Markers and Sleep Responses to Exercise
The aim of this study is to examine the reproducibility of postprandial coronary heart disease (CHD) risk marker and sleep responses to acute exercise bouts and to quantify the magnitude of individual variability in responses…
- Conditions
- Coronary Heart Disease, Cardiovascular Risk Factor, Arterial Stiffness, Blood Pressure
- Trial name
- NCT05022498
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Increased Drug Resistance
The Effects of Omega-3 Fatty Acids on Aspirin Resistance
The purpose of this study is to determine if omega-3 fatty acids enhance the antiplatelet effects of aspirin.
- Trial name
- NCT00771914
- Testing
- Aspirin, Lovaza, Both Aspirin and Lovaza
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Coronary Microvascular Disease, Coronary Artery Disease
A Non-invasive Index of Microciculatory Resistance
Coronary artery microvascular disease (CMVD) lacks reliable and non-invasive quantitative diagnosis methods. Improving coronary microcirculation has become one of the main goals of coronary heart disease treatment.
- Trial name
- NCT04554004
- Testing
- CCTA, CT-MPI, DSA, FFR
- Where
- China
- Volunteers
- 295 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Hangzhou
Coronary Heart Disease
Endothelial Cell Gene Networks of CVD
The objective of this study is to identify relevant signature gene networks of cardiovascular disease in endothelial cells derived from circulating endothelial progenitor cells of individuals with established cardiovascular…
- Trial name
- NCT03529916
- Testing
- isolation of endothelial cells precursors in blood
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tufts University
Chest Pain, Coronary Occlusion
Advanced Cardiovascular Imaging Consortium
The ACIC is a Collaborative Quality Improvement (CQI) program involving the collection of data related to: indications for Coronary Computed Tomography (CCTA), patient health characteristics, acquisition techniques of CCTA scans…
- Conditions
- Chest Pain, Coronary Occlusion, Coronary Artery Disease
- Trial name
- ACIC (NCT00640068)
- Where
- 50 sites in United States
- Volunteers
- 42,926 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Coronary Arterial Disease (CAD), Angina (Stable)
The Effect of Sublingual Nitroglycerin on Absolute Coronary Blood Flow
The goal of this clinical trial is to investigate the effect of sublingual nitroglycerin on absolute coronary blood flow in adult patients undergoing coronary angiography.
- Trial name
- FLOW-NITRO (NCT06823843)
- Testing
- Glycerin trinitrate (GTN)
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- VZW Cardiovascular Research Center Aalst
Myocardial Infarction, Stroke
Testing a Community Intervention to Increase Aspirin Use
This research will test the effect of mass media or mass media plus a clinic based education program will improve appropriate aspirin use for cardiovascular disease prevention.
- Trial name
- NCT02607917
- Testing
- Mass Media plus clinic intervention., Media
- Where
- United States
- Volunteers
- 10,800 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Coronary Artery Disease, Coronary Heart Disease
Impact of Cardiac Rehabilitation on Patient Outcomes
Objective: This study aimed to retrospectively evaluate the impact of cardiac rehabilitation (CR) on functional capacity, depressive symptoms, health-related quality of life, and sleep quality in patients with heart disease.
- Trial name
- NCT07468955
- Testing
- Exercise Based Cardiac Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Myocardial Ischemia, Heart Diseases
Cardiac Rehabilitation: Optimisation of the Functional Capacity of Patients Hospitalized With Cardiac Disease
The World Health Organization [WHO] (2021) states that Cardiovascular Diseases [CVD] are the leading cause of death in the world, and in 2019 around 17.9 million deaths were caused by CVD and the national picture is no different.
- Trial name
- NCT06546878
- Testing
- Cardiac Rehabilitation (Phase I) - nurse intervention
- Where
- Portugal
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- José Manuel Afonso Moreira
Obesity Associated Disorder, Myocardial Infarction
Association of Obesity and Cardiovascular Outcomes in Myocardial Infarction
In this study, the investigators evaluated the association between various measures of adiposity [BMI and waist circumference (WC)] and clinical outcomes in Asian patients with Myocardial Infarction who underwent percutaneous…
- Trial name
- Paradox (NCT05645926)
- Testing
- Percutaneous coronary intervention (PCI), Coronary artery bypass grafting (CABG)
- Where
- South Korea
- Volunteers
- 60,000 people, healthy volunteers welcome
- Sponsor
- Ajou University School of Medicine
Coronary Heart Disease
The Alteration of HDL Protein Composition in Patients With Coronary Heart Disease Before and After Statins Treatment
The protein composition of HDL is complicated. The investigators have identified 40 distinct proteins associated with HDL by proteomics technology, and these proteins have been confirmed to be related to the function of…
- Trial name
- NCT01543308
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
ST Elevation (STEMI) Myocardial Infarction
Bempedoic Acid in PPCI Impact on Clinical Outcome and Inflammatory Markers
Bempedoic acid in PPCI
- Trial name
- NCT07129850
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Coronary Arterial Disease (CAD)
Central vs Brachial BP, Exercise, and Coronary Artery Disease
High blood pressure (BP) is a major risk factor for coronary artery disease (CAD), with 30-70% of CAD patients having elevated BP.
- Trial name
- NCT06617117
- Testing
- High-intensity combined exercise, Moderate-intensity combined exercise
- Where
- Portugal
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.