Clinical trials: Cardiopulmonary Resuscitation (CPR)
Cardiac Arrest
Quality of Cardiopulmonary Resuscitation Without and With Defibrillator Feedback
Quality of bystander cardiopulmonary resuscitation (CPR) affect patient survival. Quality of professional CPR on patients has not been studied in detail, but it is regularly reported that the quality when tested on manikins…
- Trial name
- NCT00138996
- Testing
- automated direct feedback on CPR from defibrillator
- Where
- 3 sites in Norway, Sweden and 1 more
- Volunteers
- 300 people
- Sponsor
- University of Oslo
Cardiac Arrest, Sudden Cardiac Death
Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial
The purpose of this research study is to evaluate the effectiveness of metoprolol, a "beta blocker," in treating patients in the hospital with a cardiac arrest. It will be given intravenously (given into a vein).
- Conditions
- Cardiac Arrest, Sudden Cardiac Death, Ventricular Fibrillation, Tachycardia, Ventricular
- Trial name
- Shock n Block (NCT00401882)
- Testing
- Epinephrine, Metoprolol
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- David Haines, MD
Stereotype-threat, COVID-19
Stereotype Threat Effect on CPR Performance in Covid-19 Intensive Care Units: A Randomised Controlled Mannequin Study
Stereotype threat (ST) is an important issue that has been studied repeatedly in the psychology literature. ST is the thought that a person will be negatively evaluated and judged regarding a negative stereotype that belongs to…
- Trial name
- NCT05074446
- Testing
- stereotype threat manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cardiac Arrest
Sustained Inflation and Chest Compression vs 3:1 C:V Ratio in Asphyxiated Newborns
Newborn infants who require cardiopulmonary resuscitation at birth receive chest compression using a 3-Compression to 1-Ventilation (3:1 C:V) ratio.
- Trial name
- SUR1VE-2 (NCT06577818)
- Testing
- CC+SI (Chest compression during sustained inflation), 3:1 C:V (3:1 Compression:Ventilation ratio)
- Where
- Canada
- Volunteers
- 554 people
- Sponsor
- University of Alberta
Cardiac Arrest
Improving the Quality of Cardiopulmonary Resuscitation (CPR) During Pediatric Cardiac Arrest
Our project aims to improve the delivery and assessment of cardiopulmonary resuscitation (CPR) during pediatric cardiac arrest by introducing 2 novel approaches: 1.
- Trial name
- QCPR (NCT02075450)
- Testing
- CPRcard, Just in Time Video
- Where
- 11 sites in United States, Canada and 1 more
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
Cardiac Arrest, Post-cardiac Arrest Care
Neuroprotection Bundles For Comatose Survivors Following Cardiac Arrest
The investigators designed LAPTOPS to determine the effectiveness of a goal-directed neuroprotection bundles of active management including body temperature,PaCO2,PaO2,position,Blood glucose ,blood sodium,Blood pressure and…
- Trial name
- LAPTOPS (NCT06992843)
- Testing
- Goal-directed care bundle for neuroprotection, Usual Care
- Where
- China
- Volunteers
- 1,008 people
- Sponsor
- Xiangya Hospital of Central South University
Cardiopulmonary Arrest
Comparison of Tracheal Ultrasound With Capnography for Intubation Confirmation During CPR Wearing PPE
It is very important to ensure the tube placement in patients with cardiac arrest and unrecognized misplacement of endo-tracheal tube can lead to morbidity and mortality.
- Trial name
- NCT04690517
- Testing
- tracheal ultrasound
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Samsung Medical Center
Cardiopulmonary Resuscitation
The Critical Threshold of Pulse Oximetry Plethysmographic Waveform Parameters in High Quality CPR
The purpose of this study is to analyze the relationship of the area under the curve (AUC) and/or the amplitude (Amp) of pulse oximetry plethysmographic waveform (POP) with partial pressure of end-tidal carbon dioxide (PETCO2)…
- Trial name
- NCT03754946
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking Union Medical College Hospital
Basic Cardiac Life Support, Virtual Reality
Effectiveness of Extended Reality CPR Training Methods
The aim of this study is to explore the efficacy and safety of the extended reality (XR)-based basic life support (BLS) training.
- Trial name
- NCT04736888
- Testing
- extended-reality CPR training, conventional CPR training
- Where
- 3 sites in United States, South Korea and 1 more
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Cardiopulmonary Arrest, Cardiac Arrest
Trial of Vasopressin and Epinephrine to Epinephrine Only for In-Hospital Pediatric Cardiopulmonary Resuscitation
Cardiac arrest has a very poor prognosis, especially with prolonged efforts at resuscitation, and unfortunately, survivors are often severely neurologically impaired.
- Trial name
- Vasopressin (NCT00628550)
- Testing
- Vasopressin, Epinephrine
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of Texas Southwestern Medical Center
Cardiopulmonary Resuscitation
Cardiopulmonary Resuscitation Training Program Based on Quality Control
In a prospective, non-randomized study, all of the basic and advanced cardiopulmonary resuscitations would be analyzed. All resuscitation are planned to be performed by the above mentioned devices according to the recent…
- Trial name
- NCT03112460
- Testing
- cardiopulmonary resuscitation with Zoll R Series defibrillator and defibrillator pads with a real-time CPR feedback option and CodeReview case analysis software
- Volunteers
- 20 people
- Sponsor
- Hungarian Institute of Cardiology
Cardiac Arrest
The Schmitz-Hinkelbein Method. A New Technique for CPR in Space.
The risk of a severe medical event during long-duration spaceflight is significant and can endanger both the whole mission and crew.
- Trial name
- NCT04354883
- Testing
- External Chest Compressions on Manikin in Underwater Setting
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Köln
Out-Of-Hospital Cardiac Arrest, Cardiopulmonary Resuscitation
PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE)
The PRE-hospital Cooling to improvE carDiac arrEst Neurological outComEs (PRECEDENCE) study is a pilot feasibility trial evaluating the implementation of pre-hospital targeted temperature management (TTM) using a wearable surface…
- Conditions
- Out-Of-Hospital Cardiac Arrest, Cardiopulmonary Resuscitation, Death, Sudden, Cardiac, Therapeutic Hypothermia
- Trial name
- PRECEDENCE (NCT07421882)
- Testing
- CarbonCool® Cooling Vest
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Singapore General Hospital
Cardiopulmonary Resuscitation
Chest Compression During Resuscitation
The aim of the study was to evaluate the new mechanical chest compression machine LifeLine ARM in healthcare professionals in simulated model of cardiac arrest.
- Trial name
- NCT02703103
- Testing
- Manual chest compressions, ARM chest compressions
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Cardiopulmonary Resuscitation
Effect of Core Muscles Activation for the Increase of Quality in Cardiopulmonary Resuscitation
The purpose of this study is to determine whether core muscle activation is effective in the increase of quality of cardiopulmonary resuscitation.
- Trial name
- NCT03007680
- Testing
- Core muscle activation
- Where
- South Korea
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Emergency Medicine, Cardiopulmonary Arrest
Intravascular Access in Suspected/Confirmed COVID-19 Patient
The current COVID-19 pandemic, this is especially since the transmission of SARS-CoV-2 is thought to occur mainly through respiratory droplets generated by coughing and sneezing, by direct contact with contaminated surfaces and…
- Conditions
- Emergency Medicine, Cardiopulmonary Arrest, Shock
- Trial name
- NCT04366947
- Testing
- NIO® (Intraosseous access), Standard of Care (Intravenous access)
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Lazarski University
Cardiopulmonary Resuscitation
Manual and Mechanical Chest Compression During In-hospital Witnessed Cardiac Arrests Using Cerebral Oximetry
Post-resuscitation neurological impairment is associated with morbidity and especially with late mortality. Thus, because good neurological outcome is vital for a successful resuscitation, it is essential to have sufficient…
- Trial name
- NCT03238287
- Testing
- Mechanical chest compression, Manuel chest compression
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Eskisehir Osmangazi University
Cardiac Arrest (CA), In-Hospital Cardiac Arrest
The Ventilation During In-hospital Cardiac Arrest Study
The goal of this prospective observational study is to learn how ventilation quality parameters during cardiopulmonary resuscitation (CPR) are associated with short-term survival following in-hospital cardiac arrest of adult…
- Conditions
- Cardiac Arrest (CA), In-Hospital Cardiac Arrest, Heart Arrest
- Trial name
- VENT-IHCA (NCT06809309)
- Testing
- Positive pressure ventilation during cardiopulmonary resuscitation
- Where
- 11 sites in Denmark, Norway
- Volunteers
- 900 people
- Sponsor
- University of Aarhus
Chest Compression
Single-rescuer Pediatric Resuscitation
The objective of this pilot study was to compare the manual chest compressions (CC) versus CC feedback device TrueCPR vs mechanical CC device LifeLine ARM during simulated pediatric cardiopulmonary resuscitation
- Trial name
- SRPR (NCT02694900)
- Testing
- Manually chest compressions, Cardiopump, LifeLine ARM
- Where
- Poland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Cardiac Arrest
Assessing CPR Quality During In-Hospital Cardiac Arrest
Using an investigational monitor/defibrillator that passively records CPR quality parameters, including chest compression rate and depth and ventilation rate and volume, we are prospectively recording CPR quality during…
- Trial name
- NCT00228293
- Testing
- investigational monitor/defibrillator with CPR feedback
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Chicago