Clinical trials: Cardiopulmonary Resuscitations
Out of Hospital Cardiac Arrest
Continuous Chest Compressions vs AHA Standard CPR of 30:2
The primary aim of the trial is to compare survival to hospital discharge after continuous chest compressions (CCC) versus standard American Heart Association (AHA) recommended cardiopulmonary resuscitation (CPR) with interrupted…
- Trial name
- CCC (NCT01372748)
- Testing
- Standard CPR, Continuous chest compressions
- Where
- 7 sites in United States, Canada
- Volunteers
- 23,711 people
- Sponsor
- University of Washington
Cardiopulmonary Resuscitation
Quality of Cardiopulmonary Resuscitation Guided by AED vs Telephone-assistance
The aim of this research is to evaluate and to compare the quality of cardiopulmonary resuscitation (CPR) among untrained laypeople under two different scenarios: automated external defibrillator (AED) guided CPR or…
- Trial name
- QRCP (NCT03771911)
- Testing
- AED, Telephone
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Bionorte
CPR, Training
Evaluating the Effects of Popular Music on Cardiopulmonary Resuscitation Training
This study aims to analyze short- and long-term effects of musical memory created by using a national popular song on achieving the recommended compression rate and depth and compression-breath rate for nursing students, who…
- Conditions
- CPR, Training, Music, Nursing Students
- Trial name
- NCT06557109
- Testing
- Popular Music
- Where
- Cyprus
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Cardiopulmonary Resuscitations
Stress Coping Strategy on Perceived Stress Levels and Performance During a Simulated Cardiopulmonary Resuscitation
This study assessed the impact of a task-focusing strategy on perceived stress levels and performance during a simulated CPR scenario.
- Trial name
- NCT01826318
- Testing
- Stress coping
- Where
- Switzerland
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Out-Of-Hospital Cardiac Arrest, Trauma
AI to Improve Outcome From Traumatic Cardiac Arrest
This study evaluates data from patients in The Danish Medical Service electronical registry over a 6-year period from 2016 to 2021 with traumatic cardiac arrest.
- Trial name
- NCT05294575
- Where
- Denmark
- Volunteers
- 31,200 people
- Sponsor
- Prehospital Center, Region Zealand
Cardiopulmonary Resuscitation (CPR), ESCAPE ROOM
The Effect of Escape Room Simulation on Nursing Students' Clinical Decision-Making and Teamwork Attitudes Regarding Cardiopulmonary Resuscitation
The study was planned as a randomized controlled trial with a pre-test-post-test-follow-up design involving experimental and control groups.
- Trial name
- NCT07336511
- Testing
- Escape room
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Yildirim Beyazıt University
Cardiac Arrest, Sudden Cardiac Death
Treatment of Ventricular Tachyarrhythmias Refractory To Shock With Beta Blockers: The SHOCK and BLOCK Trial
The purpose of this research study is to evaluate the effectiveness of metoprolol, a "beta blocker," in treating patients in the hospital with a cardiac arrest. It will be given intravenously (given into a vein).
- Conditions
- Cardiac Arrest, Sudden Cardiac Death, Ventricular Fibrillation, Tachycardia, Ventricular
- Trial name
- Shock n Block (NCT00401882)
- Testing
- Epinephrine, Metoprolol
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- David Haines, MD
Cardiopulmonary Resuscitation, Cardiac Arrest
Cardiac Arrest Bundle of cARE Trial
An out-of-hospital cardiac arrest is a sudden event where the heart stops beating and a person becomes unresponsive. During this event, vital organs in the body receive no blood flow, causing them to shut down.
- Conditions
- Cardiopulmonary Resuscitation, Cardiac Arrest, Out of Hospital Cardiac Arrest
- Trial name
- CABARET (NCT05917717)
- Testing
- Neuroprotective 'bundle of care'
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Education Advancement
Airway Obstruction During BLS
Appropriate management of cardiac arrest (immediately and technically well performed) is a priority that must be taught to all citizens and future healthcare personnel, including future physicians.
- Trial name
- BLS-OBST (NCT06770920)
- Testing
- use of an observer tool when not role-playing
- Volunteers
- 112 people
- Sponsor
- Université Paris-Sud
Cardiopulmonary Resuscitation
Pulse Control Using USG and Manual Palpation Methods in Cardiopulmonary Resuscitation
The final approach adopted in Advanced Cardiac Life Support (ACLS) guidelines as defined by the American Heart Association (AHA) and the European Resuscitation Council (ERC) is to minimize the time between chest compressions in…
- Trial name
- NCT05557032
- Testing
- cardiopulmonary resuscitation
- Where
- Turkey (Türkiye)
- Volunteers
- 536 people
- Sponsor
- Izmir Katip Celebi University
Simulation Training
Effect of the Use of a Visual Feedback Device in RCP Trainings
To verify the efficacy of manikins with feedback in the training of physicians and nurses in the courses of Advanced Cardiac Life Support (ACLS) authorized by the American Heart Association (AHA) when compared to the traditional…
- Trial name
- NCT04338490
- Testing
- Feedback mannequim
- Where
- Brazil
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Cardiac Arrest (CA)
Incidence of Colon Ischemia in Patients After Cardiopulmonary Resuscitation (CPR)
Bedside colonoscopy 24-36 hours after successful CPR
- Trial name
- NCT07359313
- Testing
- colonoscopy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital Freiburg
Resuscitation, Cardiopulmonary
Effect of Early High-dose Epoetin Alfa During Cardiac Arrest (Pilot Study)
The purpose of this study is to test the possible neuroprotective effect of early high dose erythropoietin alpha after out of hospital cardiac arrest (OHCA).
- Conditions
- Resuscitation, Cardiopulmonary, Cardiac Arrest
- Trial name
- NCT00719498
- Testing
- Epo-alpha
- Volunteers
- 20 people
- Sponsor
- Janssen Cilag S.A.S.
Cardiopulmonary Resuscitation, Personal Protective Equipment
Effect of Wearing Personal Protective Equipment (PPE) on CPR Quality in Times of the COVID-19-pandemic
Background The significant risk of transmission of SARS-CoV-2 to healthcare staff mandated changes to Basic and Advanced Life Support (BLS and ALS) guidelines.
- Trial name
- NCT04548934
- Testing
- Personal protective equipment (PPE), No Personal protective equipment (PPE)
- Where
- Italy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Out of Hospital Cardiac Arrest, Computed Tomography
Timing for Computed Tomography and Post-Resuscitation Care on Short-Term Outcomes in Out-of-Hospital Cardiac Arrest
This retrospective multicenter study investigates the association between the timing of computed tomography (CT) scans and short-term outcomes in adult non-traumatic out-of-hospital cardiac arrest (OHCA) patients who achieved…
- Trial name
- NCT06936917
- Volunteers
- 5,000 people
- Sponsor
- National Taiwan University Hospital
Apnea, Cardiopulmonary Resuscitation
Head Positions to Open the Upper Airway
Ventilation during basic life support improves survival in cardiac arrest patients significantly. Unfortunately, this is in contrast to the willingness of potential rescuers to perform mouth-to-mouth ventilation.
- Trial name
- NCT00869648
- Testing
- Extension, Neutral head position, Anaesthesiologist's position
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Cardiac Arrest, Resuscitation
Mechanical Versus Manual Cardiopulmonary Resuscitation
In this study, the investigators compared mechanical and manual chest compressions in in-hospital cardiac arrest cases.
- Trial name
- NCT04422938
- Testing
- Manuel chest compressions handled by clinicians, LUCAS™ 2 Chest Compression System
- Where
- Turkey (Türkiye)
- Volunteers
- 303 people
- Sponsor
- Ankara City Hospital Bilkent
Cardiac Arrest (CA), In-Hospital Cardiac Arrest
The Ventilation During In-hospital Cardiac Arrest Study
The goal of this prospective observational study is to learn how ventilation quality parameters during cardiopulmonary resuscitation (CPR) are associated with short-term survival following in-hospital cardiac arrest of adult…
- Conditions
- Cardiac Arrest (CA), In-Hospital Cardiac Arrest, Heart Arrest
- Trial name
- VENT-IHCA (NCT06809309)
- Testing
- Positive pressure ventilation during cardiopulmonary resuscitation
- Where
- 11 sites in Denmark, Norway
- Volunteers
- 900 people
- Sponsor
- University of Aarhus
Ischemia, Reperfusion Injury
Goal-directed CPR Using Cerebral Oximetry
The proposed study is a single-center, randomized controlled pilot trial of adults who suffer in-hospital cardiac arrests. Using cerebral oxygenation and end-tidal carbon dioxide physiological targets to predict survival and…
- Trial name
- NCT04924985
- Testing
- Non-Physiological Feedback CPR, Physiological Feedback CPR
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- NYU Langone Health
Cardiac Arrest, Cardiopulmonary Arrest
ECMELLA vs. ECMO on 30-day Mortality
This international, multicenter cohort study aims to investigate outcomes after treatment with extracorporeal cardiopulmonary resuscitation (eCPR) during cardiac arrest.
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest, Extracorporeal Membrane Oxygenation Complication, Cardiogenic Shock
- Trial name
- NCT05175898
- Testing
- VA-ECMO, ECMELLA
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany