Clinical trials: Cardiovascular Risks
Heart Failure, Diastolic, Multicenter Study
Diagnosis and OutcoMes evaluAtIoN of Multicenter Patients With HFpEF Using Multimodality Imaging
The incidence of Heart failure with preserved ejection fraction (HFpEF) in Heart failure patients increases rapidly. However, the current clinical awareness is insufficient, and the cardiac structural and functional injury are…
- Trial name
- NCT04602338
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Obstructive Sleep Apnea, Pregnancy Induced Hypertension
Sleep Quality in Pregnancy and Its Impact on Pregnancy Outcomes
Hypothesis:Sleep Disorders are very common during pregnancy but the their exact role in causation of pregnancy related disorders is yet to be determined.
- Conditions
- Obstructive Sleep Apnea, Pregnancy Induced Hypertension, High-Risk Pregnancy, Restless Leg Syndrome
- Trial name
- NCT02016638
- Testing
- Polysomnography and ambulatory blood pressure recording
- Where
- India
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
CKDu, Arterial Stiffness
An Investigation Into the Cardiovascular Risk and Aetiology of CKDu in Sri Lanka
1. We hypothesise that CKDu patients will have increased arterial stiffness and thus increased all-cause and cardiovascular mortality.
- Conditions
- CKDu, Arterial Stiffness, Proteinuria, Serum Creatinine
- Trial name
- NCT02226055
- Testing
- Arterial Stiffness Assessment
- Where
- Sri Lanka
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Hypertension, Hyperlipidemia
Prioritized Clinical Decision Support (CDS) to Reduce Cardiovascular Risk
The objective of this project is to develop and implement sophisticated point-of-care Electronic Health Record (EHR)-based clinical decision support that (a) identifies and (b) prioritizes all available evidence-based treatment…
- Conditions
- Hypertension, Hyperlipidemia, Diabetes, Smoking
- Trial name
- NCT01420016
- Testing
- Prioritized Clinical Decision Support
- Volunteers
- 7,914 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Cardiovascular Diseases, Fracture
Prevalence and Risk Factors for Common Diseases
By using national databases in Sweden the aim of the present project is to: 1. Investigate if the incidence of our most common diseases, such as fracture and cardiovascular disease, has changed from 1970-2017 2.
- Conditions
- Cardiovascular Diseases, Fracture, Cancer
- Trial name
- NCT04091035
- Testing
- To describe the incidence of disease and evaluate risk factors
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Anna Nordström
Polycystic Ovary Syndrome
Evaluation of Endocrine and Metabolic Parameters in the New Diagnostic Phenotypes of Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a very frequent endocrine disease of women in reproductive age, with an estimated prevalence of 5 to 10 % according to the studied population.
- Trial name
- NCT00784615
- Testing
- Blood samples, transvaginal ultrasound
- Where
- Argentina
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Córdoba
Cardiovascular Risk Factor
South Asian Healthy Lifestyle Initiative (SAHELI)
Research show that South Asians (SA) have a high burden of Cardiovascular Disease (CVD) risk factors of which, poor diet and physical inactivity remain the major lifestyle risk factors in SA.
- Trial name
- SAHELI (NCT03336255)
- Testing
- South Asian Healthy Lifestyle Initiative (SAHELI)
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Arrhythmia, Sudden Cardiac Death
Electrophysiological Phenotyping Of Patients at Risk of Ventricular Arrhythmia and Sudden Cardiac Death
Obesity, rheumatoid arthritis (RA) and gene-specific dilated cardiomyopathy (DCM) are common medical conditions. Small-scale studies have shown that these are associated with proarrhythmic changes on 12-lead electrocardiogram…
- Conditions
- Arrhythmia, Sudden Cardiac Death, Cardiomyopathy, Dilated, Obesity
- Trial name
- EPORVA (NCT03910725)
- Testing
- Electrocardiographic imaging
- Where
- 2 sites in United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Smoking
Carotid Plaque Screening Trial in Smokers
The purpose of this study is to determine the impact of carotid plaque screening on smoking cessation and control of other cardiovascular risk factors.
- Trial name
- CAROSS (NCT00548665)
- Testing
- Carotid ultrasound for plaque screening, Brief advice for smoking cessation
- Where
- Switzerland
- Volunteers
- 536 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Cardiovascular Diseases
Eggs as Part of a Healthy Breakfast
Contrary to popular belief, previous studies have demonstrated beneficial effects of whole egg consumption in modifying biomarkers indicative of a greater risk of coronary heart disease (CHD), chronic inflammation, and insulin…
- Trial name
- NCT02297464
- Testing
- Eggs - 2 per day for breakfast, 1 packet of oatmeal per day
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Asthma, Inflammation
Vascular Implications of a Naturally Occurring Asthma Exacerbation
Although asthma is a disease of the airways, research is now showing that asthmatics are more likely to develop cardiovascular disease (CVD) compared to non-asthmatics.
- Conditions
- Asthma, Inflammation, Cardiovascular Risk Factor
- Trial name
- NCT03679299
- Testing
- Observational - No intervention
- Where
- 2 sites in Canada
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Hypertension
Embedded Community-based Heart-Age Risk Education Trial in Cinese Primary Healthcare
This study evaluates the effectiveness of a brief Heart Age-based risk education intervention embedded in routine primary care for older adults with hypertension in China.
- Trial name
- E-CHARM (NCT07045363)
- Testing
- Cognitive Intervention
- Where
- China
- Volunteers
- 358 people, healthy volunteers welcome
- Sponsor
- Duke Kunshan University
Deep Venous Thrombosis, Pulmonary Embolism
Risk Factors for Venous Thromboembolism
Deep venous thrombosis is the presence of blood clots, usually in the legs that lead to either local problems or breathing problems if the clot moves to the lungs.
- Trial name
- NCT00018772
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Chronic Disease, Diabetes Mellitus
Social Risk Score, Clinical Decision Support Tool and Closed Loop Referral for Social Risk Screen and Referral
The overarching goal of this project is to leverage health information technology (HIT) to integrate available digital information on social needs to improve care for racial and ethnic minorities and socially disadvantaged…
- Conditions
- Chronic Disease, Diabetes Mellitus, Hypertension, Congestive Heart Failure
- Trial name
- NCT05574699
- Testing
- Social Risk Score and CDS Tool, Standard of Care
- Where
- 5 sites in United States
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Sedentary Lifestyle, Cardiometabolic Risk
Effects of Aerobic and Resistance Exercise on Cardiovascular Biomarkers in Sedentary Women
This randomized controlled trial investigated the effects of aerobic and resistance exercise on cardiovascular and inflammatory biomarkers in sedentary young women.
- Trial name
- NCT07457047
- Testing
- Aerobic Exercise Training, Resistance Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Obesity, Adolescent, Lifestyle, Healthy
Mediterranean Enriched Diet for Tackling Youth Obesity
The prevalence of obesity is one of the main public health problems worldwide, reaching 18% among young people between 5 and 19 years of age in 2016. One possibility of effective treatment can be the Mediterranean diet (MD).
- Conditions
- Obesity, Adolescent, Lifestyle, Healthy, Diet, Healthy, Cardiovascular Risk Factor
- Trial name
- MED4Youth (NCT04719052)
- Testing
- Diet and behavioural intervention
- Where
- Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Diet Modification, Substance Use Disorders
The Impact of a Parenting Intervention on Latino Youth Health Behaviors
The purpose of this study is to test if a parenting program can be used to prevent substance use among Latino youth and at the same time promote healthy eating.
- Conditions
- Diet Modification, Substance Use Disorders, Diabetes Mellitus Risk, Cardiovascular Risk Factor
- Trial name
- FPNG+ (NCT03517111)
- Testing
- Nutrition/substance use prevention, Substance use prevention only, Academic success program
- Where
- United States
- Volunteers
- 844 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Pre-Eclampsia, Gestational Diabetes
SMARThealth Pregnancy: Feasibility & Acceptability of a Complex Intervention for High-risk Pregnant Women in Rural India.
Background: Pregnancy-related conditions including hypertensive disorders of pregnancy (HDPs) and gestational diabetes mellitus (GDM) carry independent risks for future cardiovascular disease in women.
- Conditions
- Pre-Eclampsia, Gestational Diabetes, Anemia
- Trial name
- NCT03968952
- Testing
- SMARThealth Pregnancy
- Where
- India
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Cardiovascular Risk Factor
Prognosis in the Elderly Chinese: the Northern Shanghai Study
The Northern Shanghai Study is a prospective community-based study, which is aimed to investigate the prognostic factors, including conventional cardiovascular risk factors and asymptomatic target organ damage, for mortality and…
- Trial name
- NSS (NCT02368938)
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Blood Pressure, Hypertension
Intervention With Riboflavin to Improve Vascular Health and ENdothelial Functioning in Genetically at- Risk Adults
High blood pressure is the leading risk factor for heart disease and stroke. Approximately 12% of the population have a particular genetic factor (known as the TT genotype) which increases the risk of high blood pressure.
- Trial name
- InteRVENE (NCT05488106)
- Testing
- Riboflavin 1.6mg/d, Riboflavin 5mg/d, Riboflavin 20mg/d
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Ulster
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.