Clinical trials: Cardiovascular Surgery
Hypertension
Bariatric Surgery and Cardiovascular Responses to Sodium Nitrate
Inorganic nitrite and nitrate can be reduced to NO and NO-related species such as S-nitrosothiols via the nitrate-nitrite-NO pathway.
- Trial name
- NCT06303830
- Testing
- Sodium nitrate
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Transurethral Resection, Wearable Devices
The Effect of Sock Developed with Wearable Technology for TUR Surgery Patients on Hypothermia and Venous Thromboembolism
The aim of this study is to examine the effect of the sock to be developed with wearable technology for patients who will undergo TUR surgery on the development of hypothermia and VTE.
- Conditions
- Transurethral Resection, Wearable Devices, Venous Thromboembolism, Hypothermia
- Trial name
- NCT05887518
- Testing
- Socks Developed with Wearable Technology
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tarsus University
Heart Failure, Systolic, Robotic Surgery
Cardiac Performance During Steep Trendelenburg Position in Patients Undergoing Robotic Surgery Surgery.
The field of robotic-assisted laparoscopic surgery increases all the time. Older and more fragile patients which are not suitable for major open surgery could be scheduled for robotic- assisted surgery.
- Trial name
- NCT06336746
- Testing
- Esophageal Doppler
- Where
- Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karlstad Central Hospital
Sepsis, Cardiopulmonary Bypass
Multi-omics Study on Gut Microbiota in Critical Ill Patients After Cardiopulmonary Bypass
Using metagenomics as well as metabolomics, the variation of the gut microbiota and host metabolite profiles of patient after undergoing CPB were explored.
- Trial name
- CPB-MUL-GM (NCT04032938)
- Testing
- extracorporeal circulation during cardiac surgery
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Vasodilatory Hypotension During or After Cardiac Surgery
ANG-First Trial (Angiotensin II as First-Line Vasopressor Therapy in Cardiac Surgery)
The purpose of this research is to evaluate the use of Angiotensin II in patients with low blood pressure post-surgery. Your information will be collected for 28 days post the procedure and initiation of the study drug to assess…
- Trial name
- NCT06487585
- Testing
- Angiotensin II
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Maryland St. Joseph Medical Center
Coronary Artery Disease (CAD), Bypass, Cardiopulmonary
Multivessel Minimally Invasive Coronary Bypass Grafting as HYBRID Revascularization Versus Conventional Off-pump Coronary Artery Bypass Grafting
The MICRA-HYBRID trial is a prospective, multicenter, randomized controlled study comparing multivessel hybrid coronary revascularization (HCR) as minimally invasive arterial bypass grafting to left-sided coronary targets (LAD…
- Conditions
- Coronary Artery Disease (CAD), Bypass, Cardiopulmonary, Minimally Invasive Coronary Revascularization Surgery, Off-pump Coronary Artery Bypass
- Trial name
- MICRA-HYBRID (NCT07314138)
- Testing
- Multivessel Hybrid Coronary Revascularization, Off-pump coronary arterial bypass grafting (OPCAB)
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
Persistent Atrial Fibrillation
Catheter Versus Thoracoscopic Surgical Ablation Strategy in Persistent Atrial Fibrillation
Atrial fibrillation(AF)is the commonest arrhythmia worldwide and can lead to significant morbidity and mortality, posing an increasing public health burden.
- Trial name
- CASA-AF (NCT01385358)
- Testing
- Thoracoscopically Assisted Surgical Ablation, Catheter Ablation
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Deep Venous Thrombosis, Colonic Cancer
Chemoprophylaxis With Rivaroxaban for Lower Limb Deep Vein Thrombosis in Colorectal Cancer
The chemoprophylaxis of deep vein thrombosis (DVT) with subcutaneous low-molecular-weight heparin (enoxaparin) in the postoperative period of elective surgeries is already well established in the literature and in clinical…
- Trial name
- Ésquilo (NCT05303818)
- Testing
- Rivaroxaban 10 MG
- Where
- Brazil
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Hospital do Servidor Publico Estadual
Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery (CABG)
Examining the Effects of Video-Assisted Discharge Education After Coronary Artery Bypass Graft Surgery on Patient Satisfaction and Anxiety
This study was conducted to examine the effects of standard and individualized video-assisted discharge education on patient satisfaction and anxiety levels following Coronary Artery Bypass Graft (CABG) surgery.
- Conditions
- Coronary Artery Disease (CAD), Coronary Artery Bypass Graft Surgery (CABG), Postoperative Discharge Education
- Trial name
- NCT07528859
- Testing
- video discharge education, individual video discharge training, discharge education
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Heart Disease
Effect of GLP-1 on Postprandial Lipid Metabolism
Individuals with obesity have an increased risk for heart disease and diabetes. There are current drugs on the market that target the hormone, Glucagon like peptide-1 (GLP-1) to treat diabetes.
- Trial name
- NCT01760772
- Testing
- Exendin-9, GLP-1, saline
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- David Dalessio
Respiratory Complication, Cardiac Disease
Active Cycle Breathing Technique (ACBT) on Respiratory Parameters, Dyspnea Related Kinesiophobia and Pain
This study aims to improve pulmonary function impairment is associated with a reduction in chest expansion, lung volume, pain perception and an impairment of the Post cardiac surgery patient's ability to cough effectively.
- Trial name
- (ACBT) (NCT06521346)
- Testing
- Active cycle breathing technique, Routine care
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Damanhour University
Hypovitaminosis D, Cardiovascular Diseases
Vitamin D Supplementation on in Major Orthopedic Surgery
Prospective, monocentric study in open, aimed at evaluating the effects of supplementation with calcifediol on left ventricular function parameters in cardiopathic subjects undergoing major orthopedic surgery.
- Trial name
- NCT03403933
- Testing
- Didrogyl
- Where
- Italy
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Anesthesia Complication, Vasopressor
Management of Postspinal Anesthesia Hypotension During Elective Cesarean Section: Baby Norepinephrine Versus Ephedrine
Background : Spinal anesthesia emerges as the preferred anesthesia technique for elective cesarean section . It offers a preferable alternative to general anesthesia because it provides better maternal safety and neonatal…
- Conditions
- Anesthesia Complication, Vasopressor, Cesarean Section Complications, Hypotension During Surgery
- Trial name
- NCT06498076
- Testing
- Norepinephrine, Ephedrine
- Where
- Tunisia
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Hopital Charles Nicolle
Coronary Artery Disease, Atrial Fibrillation (AF)
Cardiovascular Innovation & Research Institute 's NEXUS Registry, the Whole is Greater Than the Parts.
Information gathered from the patients via a disease specific questionnaire will be married to data from the National Cardiovascular Data Registry (NCDR®).
- Trial name
- NCT03428048
- Testing
- Hybrid procedure, Endocardial ablations, left atrial appendage occlusion
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cardiovascular Innovation and Research Institute
Neurogenic Thoracic Outlet Syndrome
Surgical Thoracic Outlet Decompression for Neurogenic Thoracic Outlet Syndrome
This study will determine the value of TOD (first rib resection with partial scalenectomy and neurolysis) on functionality and quality of life for patients with neurogenic thoracic outlet syndrome.
- Trial name
- STOPNTOS (NCT03748602)
- Testing
- Thoracic outlet decompression
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
Atherosclerosis, Chronic Periodontitis
Determining the Relationship Between the Atherosclerosis and Periodontopathogenic Microorganisms
Determine the relationship between the systemic indications of atherosclerosis by means of the change in the ratio of periodontopathogenic microorganisms following periodontal treatment of individuals who have been diagnosed with…
- Trial name
- NCT02977351
- Testing
- Non-surgical periodontal treatment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Peripheral Arterial Disease
The Effect of Thermal Blanket After Peripheral Artery Surgery
Peripheral arterial disease is one of the most common clinical conditions associated with cardiovascular morbidity and increased mortality, requiring exercise, antiaggregant and surgical revascularization therapy.
- Trial name
- NCT06310928
- Testing
- Thermal Blanket
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Myocardial Infarction, Unstable Angina
Evaluation of an Introductory Videotape Intervention to Improve Cardiac Rehabilitation Participation
The purpose of this study is to determine whether a pre-discharge videotape introducing the concept and benefit of a Cardiac Rehabiliation \& Secondary Prevention (CRSP) program will increase intent to participate in a CRSP…
- Conditions
- Myocardial Infarction, Unstable Angina, Coronary Angioplasty, Coronary Artery Bypass Surgery
- Trial name
- NCT00372671
- Testing
- Survey, Survey and videotape
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pupil Constriction, Iris Floppiness
Clinical Factors Associated Floppy Iris
This study is planned to investigate the incidence of intraoperative floppy iris and its relationship with pseudoexfoliation, diabetes, hypertension as well as systemic alpha-1 adrenergic blocker use.
- Conditions
- Pupil Constriction, Iris Floppiness, Iris Prolapsus From the Wound
- Trial name
- NCT00472888
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Baskent University
Wounds, Leg Ulcers
The AutoloGel™ Post-Market Surveillance (TAPS) Program
AutoloGel™ Post-Market Surveillance Program Purpose:Evaluate the incidence of hematologic and immunologic adverse events, including coagulopathies in patients with wounds to which AutoloGel™ was applied.
- Conditions
- Wounds, Leg Ulcers, Pressure Ulcers, Diabetic Foot Ulcers
- Trial name
- TAPS (NCT00762138)
- Testing
- AutoloGel System
- Where
- 2 sites in United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Cytomedix