Clinical trials: Chronic Lower Back Pain (CLBP)
Fibromyalgia, Lupus Erythematosus, Systemic
Brief Pain Exposure Therapy (BPET) For Nociplastic Pain
This study is intended to test whether a brief Zoom-based behavioral treatment can help adults with fibromyalgia (FM), Lupus, chronic pelvic pain, and chronic low back pain learn effective strategies for reducing pain, disability…
- Conditions
- Fibromyalgia, Lupus Erythematosus, Systemic, Chronic Pelvic Pain, Chronic Low Back Pain (CLBP)
- Trial name
- BPET (NCT06208514)
- Testing
- Brief pain exposure therapy (BPET)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Michigan
Chronic Low-back Pain (cLBP)
Visual Feedback Manipulation in Virtual Reality Alters Extension-evoked Pain Perception in Chronic LBP
This study investigates the potential to modify movement-evoked pain in individuals with chronic low back pain (LBP) by manipulating visual proprioceptive feedback through virtual reality (VR).
- Trial name
- CLEVER BODY (NCT06750900)
- Testing
- NORMAL CONDITION, UNDERSTATED CONDITION, OVERSTATED CONDITION
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Cardenal Herrera University
Low Back Pain
Effects of Manipulative Therapy and Pain Education in Individuals With CLBP
The burden of low back pain more than doubled in the last 20 years, probably caused by biopsychosocial factors. Some noninvasive treatments have been applied in individuals with chronic nonspecific low back pain as spinal…
- Trial name
- NCT02982382
- Testing
- Manipulative Therapy, Pain Education
- Where
- Brazil
- Volunteers
- 128 people
- Sponsor
- Santa Catarina Federal University
Chronic Low Back Pain (CLBP), Post Cesarean Section Patient
The Role of Therapeutic Ultrasound in Comparison With Electrical Dry Needling in Chronic Low Back Patients Post Cesarean Section
HYPOTHESIS Null Hypothesis (HO): There was a non-significant difference in the role of therapeutic ultrasound in comparison with electrical dry needling in chronic low back patients post cesarean-section.
- Trial name
- NCT07246369
- Testing
- Electrical Dry Needling, Ultrasound
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- University of Lahore
Chronic Low Back Pain (CLBP)
Clinical Investigation to Assess the Clinical Effect of the LumbaCure® Intervention on Patients Suffering From Chronic Low Back Pain
Low Back Pain (LBP) is one of the common causes of morbidity worldwide, with a one-month prevalence of 23.3 %. Number of people with LBP reached 577 million people in 2020.
- Trial name
- LumbaCure2302 (NCT06662032)
- Testing
- LumbaCure®, Rehab program
- Where
- 2 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Odix
Chronic Low-back Pain
VANISH for Chronic Low Back Pain
The program, called TMC-CP01, will use a combination of virtual reality, biofeedback, and psychological exercises to manage pain associated with Chronic Low Back Pain.
- Trial name
- VANISH (NCT04236804)
- Testing
- Flowly (TMC-CP01)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ajay Wasan, MD, Msc
Chronic Low Back Pain
Management of Chronic Low Back Pain in Older Adults Using Auricular Point Acupressure
Almost one-third (30%) of persons 60 years and older suffer from cLBP and cause a significant negative impact on individuals and society in the U.S.
- Trial name
- NCT03589703
- Testing
- Target ear points related to chronic low back pain (T-APA), Non-Target ear Points not related to chronic low back pain (NT-APA), Enhanced Educational Control Group (CG-2)
- Where
- 2 sites in United States
- Volunteers
- 272 people
- Sponsor
- The University of Texas Health Science Center, Houston
Chronic Low-back Pain (cLBP)
Static Core Stability vs. Extension Exercises for Chronic Low Back Pain
Chronic back pain is posteriorly occurring multi-causes pain that most commonly occurred due to lumber strains and sprains. It usually lasts 12 weeks (03 months) or longer.
- Trial name
- NCT06751173
- Testing
- Static Core Stability exercises, Mckenzie exercises, Spinal Mobilization
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Chronic Low-back Pain (cLBP)
Effects Of Vacuum Controlled Static Versus Vacuum Controlled Dynamic Dry Cupping On Pain, Range Of Motion And Disability Among Patients With Chronic Low Back Pain
This randomized controlled clinical trial aims to compare the effects of vacuum-controlled static dry cupping and vacuum-controlled dynamic dry cupping on pain intensity, lumbar range of motion, and functional disability in…
- Trial name
- NCT07702617
- Testing
- Vacuum-Controlled Static Dry Cupping, Vacuum-Controlled Dynamic Dry Cupping
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Chronic Low-back Pain (cLBP)
Therapeutic Exercise Plus Pain Neuroscience Education for Chronic Low Back Pain
### What is this study about? This study looked at whether adding pain neuroscience education (PNE) to standard therapeutic exercise helps people with chronic low back pain who are afraid of moving (a condition called…
- Trial name
- NCT07856992
- Testing
- Therapeutic exercise, Pain Neuroscience Education
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Qingdao Municipal Hospital
Chronic Low-back Pain
TENS Reduces Movement-Evoked Pain in People With CLBP
In this cross-over study 25 patients with chronic low back pain (CLBP) were tested for pain relief in 2 conditions: while using the Transcutaneous Electrical Nerve Stimulation (TENS) application and without using it.
- Trial name
- NCT04090814
- Testing
- HeatTens (HV-F311-E)
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Vrije Universiteit Brussel
Chronic Low Back Pain (CLBP)
A Superiority Trial of Radiofrequency Ablation for Low Back Pain
The purpose of the ASTRAL Study is to evaluate the effectiveness of LRFA (Lumbar radiofrequency ablation) against a control procedure.
- Trial name
- ASTRAL (NCT07222462)
- Testing
- Lumbar radiofrequency ablation with conventional electrodes (LRFA-C), Lumbar radiofrequency ablation with multi-tined electrodes (LRFA-M), Simulated lumbar radiofrequency ablation
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Washington
Low Back Pain
Efficacy Study to Evaluate Buprenorphine HCl Buccal Film in Opioid-Naive Subjects
The purpose of this study is to determine if buprenorphine hydrochloride (HCl) buccal film is effective in treating opioid-naive subjects, with moderate to severe chronic low back pain (CLBP), who require continuous…
- Trial name
- NCT01633944
- Testing
- Buprenorphine
- Where
- 60 sites in United States
- Volunteers
- 752 people
- Sponsor
- BioDelivery Sciences International
Chronic Low Back Pain (CLBP)
Modifying Lumbar Flexion Pain Thresholds in Chronic LBP Using Virtual Reality and Visual-Proprioceptive Manipulation
This study investigates the potential to modify movement-evoked pain in individuals with chronic low back pain (LBP) by manipulating visual proprioceptive feedback through virtual reality (VR).
- Trial name
- CLEVER-BODY (NCT06750887)
- Testing
- Normal condition, Understated condition, OVERSTATED CONDITION
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Cardenal Herrera University
Chronic Low Back Pain (CLBP)
RE-SCALE: Rehabilitation Engagement and Scaled Access With eXtended Reality and Artificial Intelligence
Background Chronic musculoskeletal pain, especially chronic low back pain (CLBP), is the leading cause of disability worldwide, with a burden expected to rise due to aging and increased longevity.
- Trial name
- NCT07202975
- Testing
- Mixed realities rehabilitation program, Usual Care
- Volunteers
- 314 people
- Sponsor
- Universitat Jaume I
Chronic Low-back Pain
Feasibility, Effectiveness, and Patient Experience of Online Acceptance and Commitment Therapy Plus Exercises for Older People With Chronic Low Back Pain
No study has investigated the effects of online ACT on community-dwelling older adults. Given that clinical practice guidelines have recommended exercise therapy for treating people with CLBP, a combination of ACT and exercise…
- Trial name
- NCT06576414
- Testing
- Acceptance and Commitment Therapy (ACT), back exercise, back care education
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Chronic Low-back Pain
DBS of the SCC for the Treatment of Medically Refractory CLBP
The purpose of this study is to evaluate the feasibility and preliminary efficacy of deep brain stimulation of the subgenual cingulate cortex for the treatment of chronic medically-refractory low back pain using a randomized…
- Trial name
- NCT04085406
- Testing
- Deep Brain Stimulation of the Subgenus Cingulate Cortex
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- University of California, Los Angeles
Chronic Low-back Pain (cLBP)
Pain Assessment Through Integrated Neurophysiology and Multidimensional Profiling
This observational case-control study aims to investigate the central neurophysiological mechanisms underlying non-specific chronic low back pain (CLBP) with neural mechanosensitivity, with wearable Optically Pumped Magnetometers…
- Trial name
- PAIN-MAP (NCT07846163)
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Chronic Low-back Pain (cLBP)
Clinical Research of Effectiveness and Safety of Herbal Medicine Strategy for Chronic Low Back Pain
This study is a pragmatic multicenter randomized controlled trial evaluating the effectiveness and safety of herbal medicine strategy for chronic low back pain, using standard Korean medicine treatment as the control.
- Trial name
- NCT07058376
- Testing
- Herbal Medicine Strategy, Standard Korean Medicine Treatment
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Jaseng Medical Foundation
Back Pain Lower Back Chronic
An Open Label Extension Study of Duloxetine (LY248686) in Participants With Chronic Low Back Pain
The purpose of the study is to assess the long term safety of duloxetine in participants with Chronic Low Back Pain (CLBP).
- Trial name
- NCT01914666
- Testing
- Duloxetine
- Where
- Japan
- Volunteers
- 151 people
- Sponsor
- Eli Lilly and Company