Clinical trials: Clinical Pain
Fibromyalgia
Relationships of Affect and Neuroinflammation With Clinical Pain in Veterans With Fibromyalgia
Fibromyalgia (FM) is a chronic pain condition that disproportionately impacts Veterans. Individuals diagnosed with FM patients experience lower self-esteem and positive affect, as well as greater levels of depression, anxiety…
- Trial name
- RAN (NCT06574165)
- Testing
- Moderate Intensity Continuous Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Coronary Artery Disease, Coronary Stenosis
The Flash FFR Ⅱ Study
The overall purpose of Flash FFR Ⅱ is to investigate whether coronary angiography-derived fractional flow reserve (caFFR), compared with fractional flow reserve (FFR) measured by a pressure wire, has non-inferior clinical effect…
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Myocardial Ischaemia, Coronary Circulation
- Trial name
- NCT04575207
- Testing
- caFFR, FFR
- Where
- 13 sites in China
- Volunteers
- 2,132 people
- Sponsor
- Peking University First Hospital
Trigeminal Neuralgia
MR Guided Focused Ultrasound (FUS) for the Treatment of Trigeminal Neuralgia
The purpose of this study is to assess the safety and effectiveness of MRI-guided focused ultrasound (MRgFUS) for treating Trigeminal Neuralgia.
- Trial name
- NCT04579692
- Testing
- ExAblate Transcranial treatment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Maryland, Baltimore
Fibromyalgia
Effectiveness of Physical Exercise in Women With Fibromyalgia
Fibromyalgia (FMS) is a syndrome expressed by chronic widespread body pain which leads to reduced physical function and frequent use of health care services. Exercise training is commonly recommended as a treatment.
- Trial name
- NCT00498264
- Testing
- walking program, resistance muscular exercise
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Federal University of São Paulo
Chronic Apical Periodontitis
Adjunctive Oral Probiotics in Endodontic Retreatment: Effects on Postoperative Pain and RANKL/OPG Levels
This study aimed to evaluate the effect of oral administration of probiotics as an adjunctive treatment to local intracanal medicaments, namely propolis and calcium hydroxide or empty canal, on the levels of receptor activator of…
- Trial name
- RANKL/OPG (NCT07683520)
- Testing
- Linex Adult®, Ca(OH)2 as intracanal medicament, propolis intracanal medication
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
Spinal Cord Injuries, Neuropathic Pain
Brivaracetam to Reduce Neuropathic Pain in Chronic SCI: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Spinal cord injury (SCI) is associated with severe neuropathic pain that is often refractory to pharmacological intervention. Preliminary data suggest brivaracetam is a mechanism-based pharmacological intervention for neuropathic…
- Trial name
- NCT05639946
- Testing
- brivaracetam
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Minnesota
Prostate Carcinoma, Prostate Neoplasm
Impact of Using the Airseal System With Ultra-low Pneumoperitoneum in Patients Undergoing Robot-assisted Radical Prostatectomy: A Prospective, Comparative, Randomized Clinical Study.
The AirSeal platform has been evaluated in urological surgeries, mainly in cases of malignant diseases 5,6. However, there is still a lack of data demonstrating the possible benefits of its use, which justifies the conduct of…
- Conditions
- Prostate Carcinoma, Prostate Neoplasm, Pain Intensity Assessment, Quality of Life (QOL)
- Trial name
- ARCO2 (NCT06784986)
- Testing
- The Conventional Insufflation System, AirSeal® System
- Where
- 2 sites in Brazil
- Volunteers
- 200 people
- Sponsor
- Brazilian Institute of Robotic Surgery
Sacroiliac Joint Dysfunction
Muscle Energy Techniques and Sacral Manipulation on Pain, Functional Disability and Quality of Life
The study will be randomized clinical trial. This study will be conducted in University of Lahore Teaching Hospital, Lahore, Pakistan.
- Trial name
- NCT05018780
- Testing
- Muscle Energy Technique, Sacral Manipulation
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- University of Lahore
Lower Back Pain Chronic, Lumbar Degenerative Disease
Comparison of Clinical Outcomes, Complications Rate and Treatment Costs of Mini-TLIF and MIDLIF in the Treatment of Discogenic Low Back Pain
Background Degenerative disc disease (DDD) is the leading cause of lower back pain and disability, which prevalence increasing with age. When conservative treatment fails, surgical methods of spinal fusion are employed.
- Conditions
- Lower Back Pain Chronic, Lumbar Degenerative Disease, Lumbar Disc Degeneration, Degenerative Disc Disease(DDD)
- Trial name
- MID-MIS (NCT07127380)
- Testing
- Midline Lumbar Interbody Fusion (MIDLIF), Minimally Invasive Transforaminal Lumbar Interbody Fusion (mini-TLIF)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Copernicus Memorial Hospital
Low Back Pain, Recurrent
Efficacy of Two Physiotherapy's Approaches in Chronic Low Back Pain: Is Addressing Psychosocial Factors Beneficial?
Low back pain is presently the first cause of disability worldwide. The most recommended interventions by clinical guidelines are exercises and cognitive behavioral therapy although the effect is modest.
- Trial name
- NCT04979403
- Testing
- Physiotherapy
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
Knee Arthroplasty
Effectiveness of Relaxation Methods in Total Knee Arthroplasty Patients
In this study, the effectiveness of a comprehensive training program consisting of pain management, relaxation, breathing, massage and falling components will be investigated in patients with total knee arthroplasty.
- Trial name
- NCT06009341
- Testing
- Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Muğla Sıtkı Koçman University
Patellofemoral Pain Syndrome
Comparison of Two Protocols for Patellofemoral Pain Syndrome
The patellofemoral pain syndrome (PFPS) is defined as a painful complaint in the anterior aspect of the knee, although peripatellar pain and / or retropatellar are also common.
- Trial name
- PFPS (NCT01691170)
- Testing
- Stretching Hamstring, Quadriceps Strengthening
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Colorectal Surgery
Effect of Ketamine on Postoperative Clinical Outcomes
The purpose of this research is to evaluate the effectiveness of ketamine as an analgesic adjuvant in decreasing the narcotic (opioids) analgesics during surgery, on pain management and on the later recovery after surgery in…
- Trial name
- NCT01365195
- Testing
- Ketamine high-dose, Ketamine low-dose
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Cedars-Sinai Medical Center
Chronic Venous Insufficiency
Neuromuscular Electrical Therapy in Venous Ulcers
The use of neuromuscular electrical stimulation in the treatment of venous ulcers with difficulty of repair could be an alternative therapeutic favoring devitalized tissues and hence the pain.
- Trial name
- NCT01372020
- Testing
- neuromuscular electrical stimulation
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Faculdade Evangelica do Parana
Varicose Veins
Evaluation of Endovenous Sclerotherapy for Treatment of Varicose Veins
The overall objective will be to evaluate clinical predictors of outcomes in patients who undergo endovenous sclerotherapy for the treatment of varicose veins.
- Trial name
- NCT00954980
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Early Childhood Caries
Comparing Controlled Flow Delivery Dentapen® Technique to Traditional Syringes
This study compares the effect of the controlled flow delivery Dentapen® technique to traditional syringes on pain perception during dental procedures among a group of pediatric dental patients
- Trial name
- NCT05959642
- Testing
- dentapen, Traditional metal Syringes
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Neck Pain, Psychomotor Disorders
Effectiveness of Dry Needling Shoulder Muscles on a Head Turning Task in Participants Aged 30-45 With Neck Pain
The goal of this clinical trial is to compare the immediate effects of stimulating shoulder muscles with an acupuncture needle (dry needling) on people from thirty to forty-five years old with recurrent neck pain.
- Trial name
- NCT05846022
- Testing
- Dry Needling
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University of Manitoba
Functional Abdominal Pain Syndrome
Digital Psychological Intervention for Pediatric Functional Abdominal Pain Disorders in Primary Care
The project involves researching two psychological treatments for functional abdominal pain in children. The treatments will be offered to children as an early intervention, at primary care level.
- Trial name
- FAPD (NCT06481072)
- Testing
- Digital patient education, Digital patient education and iCBT
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Chronic Migraine
Duration of Benefit for OnabotulinumtoxinA in Treatment of Chronic Migraine
To obtain a patient specific understanding of response to treatment with onabotulinumtoxinA by collecting and correlating pre and post treatment subject specific history, clinical outcomes, and histological changes.
- Trial name
- NCT02037425
- Testing
- onabotulinumtoxinA
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Cady, Roger, M.D.
Non-restorable Teeth, Intraoral Surgical Incisions
Efficacy of Using Knotless Barbed Suture vs N-Butyl Cyanoacrylate Glue Tissue Adhesive for Closure of Intraoral Surgical Incisions
This clinical study aims to compare the efficacy of knotless barbed sutures versus N-butyl cyanoacrylate glue tissue adhesive for the closure of intra-oral surgical incisions, with traditional PGA vicryl sutures as a control…
- Conditions
- Non-restorable Teeth, Intraoral Surgical Incisions, Wound Closure, Surgical Tooth Extraction
- Trial name
- KBA vs CA (NCT07491276)
- Testing
- PDO Knotless Barbed Suture, N-Butyl Cyanoacrylate Glue (PERIACRYL), 3/0 Resorbable PGA Suture
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Future University in Egypt
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