Clinical trials: Cognitive/Functional Effects
Healthy
The Investigators Conducted a Study to Examine the Impact of Wild Ginseng Extract (WG) on Exercise Performance, Cognitive Function, and Fatigue Recovery Among Twelve Healthy Adult Males
The goal of this clinical trial was to learn if Wild Ginseng extract (WG) influences exercise performance, cognitive function, and fatigue recovery from the exercise.
- Trial name
- NCT06679725
- Testing
- Wild ginseng extract
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Texas A&M University San Antonio
Brain Health, Longevity
L-serine and Strength Training in the Elderly
This study investigates whether taking the amino acid L-serine, either alone or in combination with targeted strength training, can have a positive effect on mental performance, brain function, and physical fitness in older…
- Conditions
- Brain Health, Longevity, Cognitive Performance, Strength Training Effects
- Trial name
- AAAging (NCT07466290)
- Testing
- Strength training, L-serine supplementation, Control (cornstarch)
- Where
- Austria
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Time Restricted Eating
Cerebromicrovascular Effects of Time-Restricted Eating in Older Adults
The central hypothesis of this study is that closer adherence to time restricted eating (TRE) will improve endothelial function, neurovascular (NVC) responses, resulting in improved cognitive performance, potentially through…
- Trial name
- NCT05488652
- Testing
- Time restricted eating
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Sleep Quality, Cognitive Function
Effects of Walking Exercise on Sleep Quality in Older Adults
This study aims to explore whether increasing physical activity can improve sleep quality in older adults, particularly those with poor sleep, and whether such improvements positively influence cognitive functions such as memory…
- Trial name
- NCT07027176
- Testing
- walking exercise
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yea-Ru Yang
Stroke
Effects of Aerobic Exercise on the Cerebral Arterial System, Cognitive, and Motor Function in Post-stroke Patients.
Background: Stroke is the second leading cause of death and disability worldwide and in Hong Kong, 6.2% of all registered deaths in 2020 were due to cerebrovascular disease.
- Trial name
- NCT05706168
- Testing
- treadmill exercise, Cycle ergometer exercise
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Mild Cognitive Impairment
The Effect of TPS on Cognitive Functions in Older Adults With MCI
The goal of this randomized controlled trial is to learn if Transcranial Pulse Stimulation (TPS) can improve cognitive functions in older adults with mild cognitive impairment (MCI). The study will also assess the safety of TPS.
- Trial name
- NCT06407141
- Testing
- transcranial pulse stimulation
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Executive Functions, Memory Functions
Multi-domain Versus Uni-Domain Training on Executive Control and Memory Functions of Older Adults
Age-related cognitive decline affects negatively daily living and quality of life of older adults. Previous research has shown a moderate impact of cognitive and physical training on the cognitive functioning of elders.
- Trial name
- VIBAL (NCT03823183)
- Testing
- Cognitive training, Physical training, Cognitive control
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Educación a Distancia
Schizophrenia
Functional Neuroimaging Effects of Cognitive Remediation Training
The purpose of this study is to examine behavioral and functional brain changes occuring as a result of cognitive remediation training in patients with schizophrenia.
- Trial name
- NCT00481156
- Testing
- Cognitive Remediation, Cognitive Behavioral Social Skills Training, Retest in Health Controls
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Forward Head Posture
Effects of Forward Head Posture on Cervical Proprioception, Muscle Endurance, and Cardiopulmonary Function During Cognitive-Motor Tasks Among University Students
Forward head posture is commonly observed among university students and may influence cervical sensorimotor function and physiological responses during functional activities.
- Trial name
- NCT07403422
- Testing
- No intervention
- Where
- Jordan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Abeer Abdrabo
Cognition
A Study to Investigate the Effect of Concord Grape Juice on Cognitive Function in Mums of Preteen Children
There is some evidence that polyphenols can affect cognitive function. Therefore, consumption of polyphenols has the potential to prevent cognitive impairment or even enhance cognitive performance.
- Trial name
- NCT01411631
- Testing
- Grape juice polyphenols
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Healthy
Effects of Two Different Exercises on Cognition
The aim of this study is to investigate the effectiveness of Pilates-based exercises on cognitive functions in comparison with aerobic exercises.
- Trial name
- NCT03491566
- Testing
- Clinic Pilates Group, Aerobic Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Biruni University
Benzodiazepine Adverse Reaction, Depression, Anxiety
Benzodiazepine Impact on Cognitive Function: fNIRs and PET/MRI Study
This study explores the impact of long-term benzodiazepine (BZDs) use on cognitive function and associated neuroimaging markers.
- Conditions
- Benzodiazepine Adverse Reaction, Depression, Anxiety, Benzodiazepine Dependence
- Trial name
- NCT06250842
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Ageing, Mitochondrial Function
The Effect of Fish Oils With Dairy or Plant Based Lipids on Mitochondrial and Physical, and Cognitive Function, in Elderly Humans
The aim of this study is to determine whether dairy or plant based fats combined with fish oils can alter skeletal muscle mitochondrial, physical, and cognitive function.
- Conditions
- Ageing, Mitochondrial Function, Physical Function, Cognitive Function
- Trial name
- NCT04194983
- Testing
- Fish oils and dairy fat, Fish oils and plant fat
- Where
- 2 sites in Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Healthy Older Adults
Effect of Dual Task in Aquatic Physical Therapy in Older Adults
Population ageing is associated with declines in motor and cognitive functions, which compromise autonomy and increase the risk of falls and cognitive impairment.
- Trial name
- NCT07270094
- Testing
- Aquatic Dual-Task Training, Conventional Aquatic Exercise
- Where
- Portugal
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Instituto Politécnico de Leiria
Attention Impaired, Risk-Taking
Effect of Air Pollution on the Cognitive Function of Adolescents
Previous observational studies have reported an association between higher air pollution exposure and lower attention in children.
- Conditions
- Attention Impaired, Risk-Taking, Risk Behavior, Social Preferences
- Trial name
- ATENC!Ó (NCT03762239)
- Testing
- Purifying the air with a Pure Airbox device (Zonair 3D)
- Where
- Spain
- Volunteers
- 2,123 people, healthy volunteers welcome
- Sponsor
- Barcelona Institute for Global Health
Healthy
Effects of Tolperisone on Measures of Drowsiness and Cognitive Function
A Randomized, 4-Period, Crossover Study to characterize the effects of tolperisone 200 mg and 400 mg (supratherapeutic dose) three times a day (TID) over 3 days of dosing on measures of simulated driving performance, cognitive…
- Trial name
- NCT04407377
- Testing
- Tolperisone Hydrochloride, Cyclobenzaprine Hydrochloride 10 MG
- Where
- 2 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Neurana Pharmaceuticals, Inc.
Cardiometabolic Risk Factors, Cognitive Function
The Effect of Tart Cherry (Prunus Cerasus) Concentrate on Physiological and Cognitive Function
A randomized, double blind, counterbalanced, placebo controlled independent groups design to determine the effects of 3 month supplementation with tart cherry concentrate on indices of cardiometabolic health, exercise capacity…
- Conditions
- Cardiometabolic Risk Factors, Cognitive Function, Exercise Capacity
- Trial name
- NCT04021342
- Testing
- Montmorency tart cherry concentrate
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Dehydration, Cognitive Change
The Effects of Hydration on Gut Health and Thinking
The central hypothesis is that improving hydration through increased water consumption will change the relative abundance of mucolytic bacteria found in the stool.
- Conditions
- Dehydration, Cognitive Change, Gastrointestinal Microbiota
- Trial name
- WatUP (NCT05315531)
- Testing
- Water Intake
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Anterior Cruciate Ligament Reconstruction
Neurophysiologic Correlates of Movement Planning During Complex Jump Landing Tasks and the Role of Cognitive Function
To examine the long-term effects of anterior cruciate ligament injuries and reconstructions (after successful rehabilitation) on cortical processes of motor planning during complex jump landing tasks and the relevance of…
- Trial name
- NCT03336060
- Testing
- Cortical Correlates of Jump Landing Task
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Goethe University
Mood Modulation, Modulation of Cognition
Investigation of the Acute Cognitive, Mood and Autonomic Effects of Hops in Healthy Participants
Hops have been used for many years for their supposed sedative and anxiety reducing properties and can be found in many natural remedies for stress, anxiety and sleeping that are already available to buy.
- Trial name
- NCT01376869
- Testing
- Hops Extract
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Northumbria University