Clinical trials: Cognitive Aging
Healthy
Efficacy, Transfer, and Neuro-functional Basis of a Memory Training Targeting Episodic Retrieval in Older Adults.
Aging leads to cognitive changes that affect memory, particularly episodic retrieval. These impairments are detrimental to seniors' quality of life.
- Trial name
- SPECTRA (NCT06110234)
- Testing
- Episodic Specificity Induction, Associative Memory
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Frontotemporal Lobar Degeneration, Aging
Social Cognition in Ageing and in Frontotemporal Lobar Degeneration
The purpose of this study is to examine the age and the neurodegenerative disease effects on social cognition. Secondary goals are to better understand the relationships between different component of social cognition, executive…
- Trial name
- COSIMAGE (NCT01962064)
- Testing
- Cognitive assessment, Brain imaging examination MRI
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Aging, Cognitive Change
Enhancing Cognitive Control Abilities Using Mobile Technology in a Senior Living Community
The goal of this study is to test the feasibility of launching a personalized digital health assessment and remediation program for the older adults in senior living communities based upon an initial characterization of these…
- Trial name
- ACCT (NCT04905849)
- Testing
- Adaptive Cognitive Control Trainer (ACCT), Active Control App
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Aging, Fall Risk Factors
Use of Virtual Reality for the Assessment of Attentional and Reaction Abilities for Fall Risk Evaluation
Aging is a condition characterized by a general decline in physical and cognitive performance, however its effects on various functions are still controversial.
- Conditions
- Aging, Fall Risk Factors, Sleep
- Trial name
- NCT06940245
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Mild Cognitive Impairment
Maintaining Independence and Quality of Life in Aging Adults Through Targeted Cognitive Training
Mild Cognitive Impairment, Alzheimer's Disease and Parkinson's Disease all represent a range of degenerative conditions that have cognitive impairments which all limit the ability for older individuals to self-manage care…
- Trial name
- NCT04539132
- Testing
- ABI Wellness Program
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kwantlen Polytechnic University
Cognitive Decline, Aging
Zinde Zihin Program to Reduce Alzheimer's Disease Risk in Adults Aged 65 and Older
This study aims to evaluate the feasibility and implementation of the Zinde Zihin ("Fit Mind") multidomain lifestyle program for older adults aged 65 years and older living in public nursing homes.
- Conditions
- Cognitive Decline, Aging, Alzheimer Disease
- Trial name
- ZZ-MIND (NCT07244848)
- Testing
- Zinde Zihin (Fit Mind) Multidomain Lifestyle Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Burdur Mehmet Akif Ersoy University
Healthy Older Adults, Healthy Young Adults
Effects of Feedback and Aging on Aiming Movements in Virtual Reality
This study has two main objectives: First, to better understand how a motor task commonly used by researchers, known as the Fitts' task, is performed in virtual reality.
- Trial name
- NCT07435506
- Testing
- VR-augmented specific feedback, VR-augmented global feedback, R-intrinsic feedback
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aix Marseille Université
Cognitive Dysfunction, Cognitive Aging
Three-month Chan-Chung Qigong Improves Physical Function Performance and Quality of Life
The purpose of this study aimed to evaluate the effect of the three-month Chan-Chung qigong program in improving physical functional performance and quality of life in patients with mild to moderate cognitive impairments.A…
- Conditions
- Cognitive Dysfunction, Cognitive Aging, Grip, Exercise Training
- Trial name
- NCT04904991
- Testing
- Chan-Chuang qigong
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Healthy Aging
Uncovering the Cognitive and Neural Mechanisms Underlying Cognitive Time
Time processing, the ability to process and encode temporal information, is essential for cognitive functioning and for a large number of daily life activities.
- Trial name
- TIMES (NCT06349213)
- Testing
- FDOPA injection before PET imaging, Time perception tasks, fMRI imaging
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Risk Behavior, Cognitive Decline
Efficacy of a Multidomain Intervention on Lifestyle Risk Factors for Dementia Prevention
Alzheimer's Disease (AD) and other Dementias have far-reaching consequences on the lives of sufferers and their loved ones, not to mention the impact on the healthcare system.
- Trial name
- NCT06748625
- Testing
- Luci Coach-Assisted Intervention
- Where
- Canada
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- LuciLab
Dance, Older Adults
Dose-response Effect of Community Dance Programme
The goal of this interventional study is to examine the dose-response effect of Community Dance Programme (CDP) on the physical, cognitive and psychological health of pre-frail and mildly frail community-dwelling older adults.
- Conditions
- Dance, Older Adults, Frailty at Older Adults, Active Ageing
- Trial name
- NCT07081191
- Testing
- Dance, Active Control
- Where
- Singapore
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Aging
Evaluation of the Effects of the New Program for Cognitive Enhancement and Improvement in the Elderly
The purpose of this study is to investigate the effect of cognitive rehabilitation program on the improvement of cognitive functions in normal elderly subjects.
- Trial name
- NCT03401775
- Testing
- Cognitive rehabilitation program
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Age-Related Loss of Skeletal Muscle Mass, Aging
Agility Training for Older Adults to Improve Fall Risk Factors
In this randomized controlled trial the effect of 4 months of multi-component (strength, balance, cognition, endurance) exercise training intervention on measures of neuromuscular performance, cognition, and endurance as well as…
- Conditions
- Age-Related Loss of Skeletal Muscle Mass, Aging, Sarcopenia, Cognitive Decline
- Trial name
- AgilE (NCT05727254)
- Testing
- Agility training, Exercise recommendations, Exercise diary
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Oliver Faude
Aging, Alzheimer Disease
Links Between Cognitive Deficits During Normal or Pathological Aging and Slow Waves Measured in EEG
With age, memory processes (encoding, consolidation and retrieval) as well as daytime vigilance are altered. Sleep is also impaired in older adults, notably slow waves that are known to play a key role in memory consolidation.
- Trial name
- MemoAge (NCT06501495)
- Testing
- video polysomnography, Attention task
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cognitive Health, Healthy Aging
Successful Aging and Enrichment (SAGE)
Progress has been made in understanding the impact of different kinds of structured intervention programs in improving cognitive processing and performance in older adults, and in determining whether there is electrophysiological…
- Trial name
- SAGE (NCT05128396)
- Testing
- Cognitive Stimulation, Mindfulness training, Physical Activity
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Memory Decline, Cognitive Decline
Anti-inflammatory Probiotics in Cognitive Functioning
The goal of this study is to explore the potential impact of an anti-inflammatory probiotic mixture of psychobiotics including Bifidobacterium longum Rosell®-175 and Lactobacillus helveticus Rosell®-52 on cognitive functions in…
- Conditions
- Memory Decline, Cognitive Decline, Cognitive Aging
- Trial name
- CoProM (NCT07165977)
- Where
- Poland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Alzheimer Disease (AD), Mild Cognitive Impairment (MCI)
China HEalthy Aging and Dementia Study (HEAD)
The China HEalthy Aging and Dementia (HEAD) study is a large-scale, community-based, multi-center prospective cohort study covering eastern, northern, southern, and central-western regions of China.
- Conditions
- Alzheimer Disease (AD), Mild Cognitive Impairment (MCI), Dementia, Vascular Dementia (VaD)
- Trial name
- NCT07912710
- Where
- 30 sites in China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Fudan University
Aging, Alzheimer Disease
Heart Rate and Breathing Effects on Attention and Memory
In the current study, we will examine how daily paced breathing affects plasma amyloid beta levels and the rate of learning in older adults.
- Conditions
- Aging, Alzheimer Disease, Age-related Cognitive Decline
- Trial name
- HeartBEAM (NCT05602220)
- Testing
- Brain training, Paced breathing
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Cognitive Change, Cytokine Levels
The Effect of Oral Use of Lyophilised Royal Jelly on Cognitive Functions and Immune System in Elderly Individuals
Dementia is a significant public health problem, affecting 47 million people worldwide in 2015, according to World Health Organization data. It is expected to increase to 75 million in 2030 and reach 132 million in 2050.
- Conditions
- Cognitive Change, Cytokine Levels, Neuroinflammation
- Trial name
- NCT06404203
- Testing
- Balparmak Apitera Royal Jelly Herbal Capsule Food Supplement 500 mg/day, Balparmak Apitera Royal Jelly Herbal Capsule Food Supplement 1000 mg/day, Balparmak Apitera Royal Jelly Herbal Capsule Food Supplement 1500 mg/day
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medipol University
Cognitive Decline, Cognitive Impairment
Effects of Cognitive Intervention on Cognition, Mobility and Brain Electrocortical Activity
Within this project the investigators tested the effectiveness of 2-month of computerized cognitive training (CCT) on CogniFit online platform on 77 older adults, which were randomly divided into intervention and control group.
- Conditions
- Cognitive Decline, Cognitive Impairment, Aging, Motor Coordination or Function
- Trial name
- GIBKOP (NCT03860441)
- Testing
- Computerized cognitive training
- Where
- Slovenia
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Science and Research Centre Koper