Clinical trials: Communication Disorders, active
Stroke Rehabilitation, Aphasia, Broca
Music Therapy for Rehabilitation in Post-stroke Non-fluent Aphasia: the Indian Adaptation
The goal of this Interventional Study is to develop and test the Indian Adaptation of Melodic Intonation Therapy (MIT) for Indian patients in with post-stroke Non-Fluent Aphasia (PSNFA).
- Trial name
- NCT06323330
- Testing
- Speech rehabilitation
- Where
- 3 sites in India
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences
ADNP, Helsmoortel-Van Der Aa Syndrome
ADNP Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing ADNP-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.
ADNP, also known as Activity Dependent Neuroprotective Protein, is a rare neurodevelopmental disorder caused by mutations encompassing the ADNP gene on chromosome 20.
- Conditions
- ADNP, Helsmoortel-Van Der Aa Syndrome, Autism Spectrum Disorder
- Trial name
- NCT03718936
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Aphasia, Stroke
Exploratory Evaluation of the Digital Therapeutic Device Zenicom for Subacute Stroke Aphasia
Clinical Trial Title A Multicenter, Single-Blind, Prospective, Randomized, Exploratory Clinical Trial to Evaluate the Safety and Efficacy of the Digital Therapeutic Device 'Zenicom' for Improving Aphasia in Patients with Subacute…
- Trial name
- NCT07397923
- Testing
- Zenicog, Conventional Speech Therapy
- Where
- 3 sites in South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Bundang Hospital
Gut-Brain Disorders, GERD Without Erosive Esophagitis
Neuroregulators for the Treatment of Diseases Associated With Esophageal-brain-gut Axis Communication Abnormalities.
Gastroesophageal reflux disease (GERD) poses a challenging medical condition to manage, with up to 40% of patients showing refractory to standard medical intervention, which usually begins with a proton pump inhibitor (PPI).
- Trial name
- NCT06778824
- Testing
- Takepron, Zoloft 50Mg Tablet, Imipramine Pill
- Where
- Taiwan
- Volunteers
- 610 people
- Sponsor
- Hualien Tzu Chi General Hospital
Developmental Delay
School-based Support for Pre-school Aged Children With Developmental Disabilities and Delays
This proposal aims to test whether a proposed community-clinical linkage (CCL), an educational-medical linkage model, improves access to school-based services and subsequent child, parent, family and health service outcomes and…
- Trial name
- PreM (NCT06145659)
- Testing
- Preschool and Me
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Spondylitis, Ankylosing, Mobile Phone Use
Exploratory Investigation of the Acceptance and Utility of 14-day Trial Periods and Application-related Outcome Measurement (AbEM) Within the Routine Prescription of the DiGA Axia.
This prospective, multicenter, controlled real-world quality management study explores the acceptance and utility of two measures discussed in the context of the German Digital Act (DigiG) for the digital health application…
- Trial name
- RAEMD (NCT07561255)
- Testing
- Test-phase with immediate access, Standard procedure
- Where
- 7 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Wuerzburg University Hospital
Autism Spectrum Disorder, Autism
Mitochondrial Dysfunction in Autism Spectrum Disorder
Researchers at Arkansas Children's Hospital Research Institute are conducting a study about mitochondrial function in children. The study involves up to 5 visits to Arkansas Children's Hospital with fasting blood draws…
- Conditions
- Autism Spectrum Disorder, Autism, Mitochondrial Disease, Developmental Delay
- Trial name
- Mito (NCT02000284)
- Where
- United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Communication Disabilities
Implementation of Communication Disability Collection and Accommodations in Primary Care Settings
This multi-methods-multi-site study aims to adapt and evaluate the effects of an implementation support package of strategies to assist primary care clinics in documenting patients' communication disability (CD) and accommodation…
- Trial name
- DECA (NCT07656584)
- Testing
- Implementation Support Package
- Where
- 5 sites in United States
- Volunteers
- 126,870 people
- Sponsor
- NYU Langone Health
Healthcare Access, Experience
Learning Differences in Medical Education
A learning difference or disability is a reduction in intellectual ability (GMC, 2024). It causes lifelong difficulty with everyday activities. Different individuals require different levels of support.
- Conditions
- Healthcare Access, Experience, Learning Disabilities
- Trial name
- NCT07585708
- Testing
- Experience of healthcare
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Nottingham
Brain Development, Behavior Disorders, Child
The Brain Mechanism of Social Emotion and Communication in Infants Aged 0 to 6 Years
This study explores the relationship between brain development and infants' social emotion and communication ability, as well as the role of genetic factors and maternal exposure during pregnancy (e.g., environmental exposures…
- Conditions
- Brain Development, Behavior Disorders, Child, Intellectual Developmental Disorders
- Trial name
- NCT05040542
- Testing
- maternal exposure during pregnancy
- Where
- China
- Volunteers
- 3,001 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Acute Kidney Injury, Acute Kidney Injury (AKI)
COordiNated CommuNication, Education, and Care Transitions After Acute Kidney Injury (CONNECT-AKI)
The goal of this clinical trial is to learn whether different ways of providing information and follow-up support after acute kidney injury, also called AKI, can improve care transitions for adults being discharged from the…
- Trial name
- CONNECT-AKI (NCT07626268)
- Testing
- AKI Discharge Summary Template, Chat-Based Educational Messaging Program
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Northwell Health
Stroke, Acute, Apoplexy; Brain
Artificial Intelligence (AI) Support in Medical Emergency Calls
More than 12.000 patients suffer acute stroke in Norway every year, but less than half of them reach hospital within the current treatment window for thrombolysis.
- Conditions
- Stroke, Acute, Apoplexy; Brain, Emergencies, Communication, Multidisciplinary
- Trial name
- AISMEC (NCT04648449)
- Testing
- Artificial intelligence on emergency calls
- Where
- Norway
- Volunteers
- 1,000 people
- Sponsor
- Haukeland University Hospital
Fibromyalgia (FM), Pain
Analysis of Facial Expressions for Pain Recognition in Fibromyalgia: Using Artificial Intelligence and Biomarkers
Fibromyalgia (FM) is a chronic musculoskeletal pain syndrome with characteristics of generalized body pain, low pain threshold, tenderness and stiffness in muscles, tendons and joints.
- Conditions
- Fibromyalgia (FM), Pain, Catastrophizing Pain
- Trial name
- Fibromyalgia (NCT06813352)
- Where
- Brazil
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas de Minas Gerais
Multiple Myeloma, Myelodysplastic Syndromes
Compassionate Communication and Advance Care Planning to Improve End of Life Care in Treatment of Hematological Disease (ACT)
Patients diagnosed with hematologic cancer are at substantial risk of dying, as 5-year survival among patients with acute myeloid leukemia is 20 % and only every second patient treated for incurable myeloma lives 5 years after…
- Conditions
- Multiple Myeloma, Myelodysplastic Syndromes, Lymphoma, Acute Myeloid Leukemia
- Trial name
- ACT (NCT05444348)
- Testing
- Advance consultation concerning your life and treatment (ACT )
- Where
- 7 sites in Denmark
- Volunteers
- 920 people
- Sponsor
- Christoffer Johansen
Predictive Modeling
Refining Risk Prediction Models for Older Adults Using Electronic Health Records
This study aims to improve how lab results are communicated to older adults by refining a predictive model that uses electronic health record (EHR) data.
- Trial name
- NCT06995365
- Testing
- Risk Prediction Model
- Where
- United States
- Volunteers
- 18,000 people
- Sponsor
- University of California, Los Angeles
Stroke, Aphasia
Study of the Participation of People With Aphasia Post Stroke and Their Caregivers in Valladolid Region (Spain)
The objective of this study is to determine the level of community participation of people with post-stroke aphasia and their caregivers, as well as the factors that facilitate or interfere with this participation in the…
- Trial name
- SPART-A (NCT06948721)
- Volunteers
- 50 people
- Sponsor
- Centro Integral de Rehabilitación
Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Development and Test of a Headset for BCI Until Obtaining an Efficient and Comfortable System That Can be Used in Daily Practice by ALS People
"Brain-computer interfaces (BCIs) are computer-based systems that acquire brain signals, analyze them, and translate them into commands that are relayed to an output device to carry out a desired action.
- Conditions
- Amyotrophic Lateral Sclerosis, Motor Neuron Disease, Spinal Cord Diseases, Alternative Communication Devices
- Trial name
- TECH-ICOPA (NCT04380649)
- Testing
- New headset prototype
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Breast Cancer Prevention
MELIORA Virtual Coach Intervention for Breast Cancer Prevention
Breast cancer (BC) is the most commonly diagnosed cancer in women worldwide, with early-onset cases increasing due to genetic and lifestyle factors.
- Trial name
- MELIORA (NCT07200427)
- Testing
- MELIORA Virtual Coach Intervention, Control (generic advice)
- Where
- 7 sites in Greece, Lithuania and 2 more
- Volunteers
- 2,080 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Developmental Language Disorder
Syntactic Intervention for Cantonese-speaking Children With DLD
The goal of this clinical trial is to compare the efficacy of explicit vs. implicit intervention on subject relative clause production in Cantonese-speaking children with Developmental Language Disorder (DLD).
- Trial name
- NCT06954194
- Testing
- Explicit intervention (Shape Coding+syntactic priming), Implicit intervention (syntactic priming only)
- Where
- Hong Kong
- Volunteers
- 32 people
- Sponsor
- The Hong Kong Polytechnic University
Developmental Language Disorder
Sentence Prediction in Developmental Language Disorder
Millions of children - 7-12% of the school-age population - have developmental language disorder (DLD), a disorder that affects language learning, comprehension, and use.
- Trial name
- NCT07510854
- Testing
- Thematic role, Sentence complexity
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home