Clinical trials: Contraceptive Devices
Acceptance Processes
Evaluation of the Impact of an Oral and Practical Presentation of Intrauterine Devices by a Health Professional on Women's Opinion as a Possible Contraceptive Method
Contraception among women in France has evolved considerably and has become a frequent reason for consultation in general practice in view of the growing shortage of gynaecologists practising in towns.
- Trial name
- EPODIU (NCT05317715)
- Testing
- Group A, who will complete a questionnaire before receiving information about intrauterine devices, Group B who will answer a questionnaire after having the information about the intrauterine devices
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Raincy Montfermeil Hospital Group
Contraception
A Study of Efficacy and Safety With the Transdermal Contraceptive System Versus Mercilon.
The purpose of the study was to compare the contraceptive efficacy and safety of the transdermal patch to Mercilon.
- Trial name
- NCT00236782
- Testing
- norelgestromin + ethinyl estradiol; mercilon
- Volunteers
- 1,517 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Inflammatory Disease
Pro-inflammatory Cytokines in Case of Essure®
It is estimated that 750,000 women (including 200,000 French) have benefited from permanent sterilization by ESSURE® contraceptive implant.
- Trial name
- ESCYTO (NCT05944822)
- Testing
- pro-inflammatory cytokines
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Hospices Civils de Lyon
Contraception
A Trial in Healthy Female Subjects to Compare the Pharmacokinetics of Ethinyl Estradiol of NuvaRing®, a Contraceptive Patch (EVRA(TM)) and an Oral Contraceptive (Microgynon® 30) (Study 34237 (P06650)) (COMPLETED)
An open-label, randomized, parallel group trial in healthy female subjects to compare the pharmacokinetics of ethinyl estradiol (EE) of NuvaRing®, a contraceptive patch (EVRA(TM)) and an oral contraceptive (Microgynon® 30).
- Trial name
- NCT01044056
- Testing
- Levonorgestrel (LNG)/Ethinylestradiol (EE) oral contraceptive tablets, norelgestrominum and ethinylestradiol patch oral contraceptive patch, Nuvaring ™ (etonorgestrel/ethinylestradiol)
- Volunteers
- 24 people
- Sponsor
- Organon and Co
Contraception
Oral Androgens in Man-4: (Short Title: Oral T-4)
The protocol was designed to address the hypothesis that oral testosterone enanthate plus dutasteride can suppress the secretion of LH and FSH after four weeks of administration.
- Trial name
- NCT00399165
- Testing
- Testosterone Enanthate, Dutasteride
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Washington
Contraception
Evaluation of a Novel Technique for Intrauterine Contraceptive Devices Insertion
The intrauterine devices are a safe, reliable, long-acting and reversible contraceptive method. It is also sound safe and cheap contraceptive methods available and is nearly maintenance free for up to 10 years.
- Trial name
- NCT02842177
- Testing
- Classic group, Uterine sounding sparing group, Transvaginal ultrasound
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Assiut University
Pain, Acute, Anesthesia, Local
Intracervical Anesthesia and Pain Associated With Intrauterine Contraceptive Insertion
The primary aim of our study is to evaluate the effect of intracervical anesthesia on pain scores immediately following levonorgestrel-releasing intrauterine system (LNG-IUS) insertion in nulligravida women.
- Conditions
- Pain, Acute, Anesthesia, Local, IUD Insertion Complication
- Trial name
- NCT03111342
- Testing
- Anesthesia, Dry-needling
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Menstrual Problem, Quality of Life
Menstrual Wellbeing in Woman Living in Turkey; an Epidemiological Study
Women with endometriosis in our country and around the world face various difficulties during their menstrual periods in reproductive age.
- Trial name
- NCT05442541
- Testing
- not included any interventions(Evaluation of menstrual well-being in women of reproductive age, field survey study)
- Where
- Turkey (Türkiye)
- Volunteers
- 1,829 people, healthy volunteers welcome
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Polycystic Ovary Syndrome (PCOS)
Efficacy of Oral Contraceptive, Progesterone, and Inositol on Menstrual Regulation in PCOS
This cross-sectional study aims to compare the effectiveness of oral contraceptives, oral progesterone (didrogesterone), and inositol in regulating menstrual cycles among women diagnosed with polycystic ovary syndrome (PCOS).
- Trial name
- NCT07242131
- Testing
- Combined Oral Contraceptive (Ethinylestradiol 0.03 mg + Drospirenone 3 mg), Inositol mid-level volume, Dydrogesterone Pill
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ege University
Contraception
Safety, Tolerability, and Efficacy of ellaOne® (Ulipristal Acetate) for Emergency Contraception in Postmenarcheal Adolescent Girls and Women
The purpose of this observational study is to assess the safety and tolerability of ellaOne® in routine conditions of use for emergency contraception in postmenarcheal adolescents and adult women who want to prevent pregnancy up…
- Trial name
- NCT01107106
- Testing
- ellaOne® (ulipristal acetate)
- Where
- 6 sites in United States, Sweden and 1 more
- Volunteers
- 579 people, healthy volunteers welcome
- Sponsor
- HRA Pharma
Cardiovascular Diseases, Coronary Disease
Myocardial Infarction and Current Oral Contraceptive Use
To assess whether current oral contraceptive (OC) use (within the previous month) increased the risk of myocardial infarction. Also, to assess the combined effects of cigarette smoking and oral contraceptive use.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Myocardial Infarction, Heart Diseases
- Trial name
- NCT00005241
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Female Sexual Function
The Female Sexual Functions With Progestogen-only Contraception
Female sexual dysfunction is age-related, progressive, and very common condition. The physiology of the female sexual function is a complex condition affected by emotional, medical and hormonal elements.
- Trial name
- NCT02579590
- Testing
- Depot Medroxyprogesterone Acetate 150 mg, Implanon( 68 mg etonogestrel implant), Cerazette pills (75 micrograms desogestrel)
- Where
- Egypt
- Volunteers
- 444 people, healthy volunteers welcome
- Sponsor
- Assiut University
Epilepsy
Effect of BIA 2-093 on the Pharmacokinetics of a Combined Oral Contraceptive.
Single centre, two-way crossover, randomised, open-label study in 20 healthy female volunteers.The volunteers received an oral single-dose of a combined contraceptive containing with an oral once daily dose of 1200 mg of BIA 2-093
- Trial name
- NCT02281448
- Testing
- BIA 2-093, Contraceptives, Oral, Combined
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Opiate Addiction, Pregnancy
Immediate Postpartum Nexplanon Placement in Opioid Dependent Women
The investigators have designed a single site, Phase IV open label, prospective observational clinical trial to compare the effect of immediate postpartum Nexplanon placement (IPP) versus standard postpartum contraceptive care…
- Conditions
- Opiate Addiction, Pregnancy, Contraceptive Behavior, Sexual Behavior
- Trial name
- NCT02657148
- Testing
- Nexplanon (etonogestrel contraceptive implant), Standard postpartum contraceptive care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Pittsburgh
Contraception
PARIS or PAtch RIng Study: A Trial to Evaluate NuvaRing Versus OrthoEvra
This is an open-label prospective, multicenter, randomized trial to compare continuation rates into the fourth cycle of women using either the NuvaRing or OrthoEvra.
- Trial name
- PARIS (NCT00269620)
- Testing
- ethinyl estradiol/etonogestrel vaginal ring, ethinyl estradiol/norelgestromin transdermal contraceptive
- Where
- 10 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pelvic Pain Associated With Refractory Endometriosis
A Safety & Efficacy Study of BGS649 in Women With Refractory Endometriosis
The purpose of this study is to determine efficacy, safety, tolerability and pharmacokinetics of multiple doses of BGS649 with concurrent daily administration of combined oral contraception in patients with refractory…
- Trial name
- NCT01116440
- Testing
- BGS649
- Where
- 44 sites in United States, Puerto Rico
- Volunteers
- 27 people
- Sponsor
- Mereo BioPharma
Hepatitis C
Investigation Of The Effect Of Steady State Filibuvir On The Pharmacokinetics Of Oral Contraceptives (Levonorgestrel And Ethinyl Estradiol)
The purpose of this study is to estimate the effect of filibuvir on the pharmacokinetics of ethinyloestradiol [EE] and levonorgestrel [LN], to assess the safety and tolerability of 600 mg BID of filibuvir in healthy women and to…
- Trial name
- NCT00918476
- Testing
- filibuvir + Oral Contraceptives
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Volunteer
A Phase 1 Study to Assess the Effect of ABBV-722 on Ethinyl Estradiol and Levonorgestrel Drug Levels in Healthy Adult Female Participants
The objective of this study is to assess the effect of repeated doses of ABBV-722 on the single dose pharmacokinetics (PK) of ethinyl estradiol and levonorgestrel.
- Trial name
- NCT07502417
- Testing
- Ethinyl Estradiol + Levonorgestrel, ABBV-722
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- AbbVie
Contraception
Comparative Bioavailability of Two Injectable Suspension Formulations of Medroxyprogesterone Acetate+Estradiol Cypionate
This clinical trial evaluated the comparative bioavailability of two injectable suspension formulations of medroxyprogesterone acetate + estradiol cypionate, a test (Depomês®, 25 mg/mL medroxyprogesterone acetate + 5 mg/mL…
- Trial name
- NCT03443089
- Testing
- Test formulation, Reference formulation
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Galeno Desenvolvimento de Pesquisas Clínicas
Contraception, Hiv
Contraceptive/HIV Affecting Risk in Adolescents
This study will evaluate the impact of hormonal contraceptives on HIV risk associated with changes to the innate immunity in the female genital tract in a cross-sectional study.
- Trial name
- CHARA (NCT03301480)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Pittsburgh