Clinical trials: Cost-Effectiveness
Nonfunctioning Kidney, Renal Cell Carcinoma (RCC)
Laparoscopic Versus Open Nephrectomy : Clinical Effectivness and Cost Analysis
To evaluate and compare clinical effectiveness (operative time, blood loss, hospital stay, complications and etc) and cost analysis' between laparoscopic nephrectomy and open nephrectomy .
- Trial name
- NCT07461090
- Testing
- open or laparoscopic nephrectomy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Sarcomas
An Adequate Cost Effective Follow Up Protocol For Bone and Soft Tissue Sarcomas
Bone and soft tissue sarcomas are rare tumors, accounting for approximately 1% of all adult malignancies. The majority of bone and soft tissue sarcomas occur in the extremities.
- Trial name
- TOSS (NCT05827458)
- Where
- India
- Volunteers
- 500 people
- Sponsor
- Tata Memorial Hospital
Mouth, Edentulous, Complete Edentulism
Cost-effectiveness of the Single-implant Mandibular Overdenture Versus Mandibular Conventional Denture
This is a randomized clinical trial designed to assess the 1-year effectiveness of two treatment modalities for the mandibular edentulists: conventional complete dentures and single-implant mandibular overdenture.
- Trial name
- NCT03463174
- Testing
- Mandibular overdenture, Mandibular complete denture
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Heart Failure
Telemedicine for Patients Suffering From Heart Failure (Danish Telecare North Trial)
There are two main aims in this study. The first objective is to evaluate whether a particular telehealth solution, in addition to standard treatment and care, lead to a significant decrease in the mortality and an increase in…
- Trial name
- TCN (NCT02860013)
- Testing
- Telemedicine
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Aalborg University
HPV - Anogenital Human Papilloma Virus Infection, HSIL, High Grade Squamous Intraepithelial Lesions
E6/E7 mRNA Performance to Detect HSIL and Cost-effectiveness Analysis of This Screening Strategy in HIV + MSM
This study evaluates the positive and negative predictive value of E6/E7 mRNA expression for anal HSIL and its capacity to predict incident HSIL in HIV + MSM. We also analyse the cost-effectiveness of this new screening strategy.
- Conditions
- HPV - Anogenital Human Papilloma Virus Infection, HSIL, High Grade Squamous Intraepithelial Lesions, Anal Cancer, Hiv
- Trial name
- ELAVI-67 (NCT03357991)
- Where
- Spain
- Volunteers
- 355 people
- Sponsor
- Hospital Universitari de Bellvitge
Diabetic Macular Edema
Comparing the Effectiveness and Costs of Bevacizumab to Ranibizumab in Patients With Diabetic Macular Edema (BRDME)
The primary objective is to demonstrate the non-inferiority of bevacizumab to ranibizumab in the treatment of patients with DME (OCT central area thickness > 275 μm) as determined by the change in best-corrected visual acuity…
- Trial name
- BRDME (NCT01635790)
- Testing
- Ranibizumab, Bevacizumab
- Where
- Netherlands
- Volunteers
- 246 people
- Sponsor
- Prof. dr. R.O. Schlingemann
Myocardial Infarction, Anemia
Cost-effectiveness and Cost-utility of Liberal vs Restrictive Red Blood Cell Transfusion Strategies in Patients With Acute Myocardial Infarction and Anaemia.
Anemia in patients with myocardial infarction (MI) is a relatively frequent issue, resulting in poorer outcome. There is equipoise regarding which transfusion strategy is best, and there is an international consensus on the…
- Conditions
- Myocardial Infarction, Anemia, Blood Transfusion
- Trial name
- REALITY (NCT02648113)
- Testing
- Restrictive transfusion, Liberal transfusion, red blood transfusion
- Where
- 2 sites in France, Spain
- Volunteers
- 668 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Overweight, Obesity
Long-term Health and Economic Effects of an Individualized Lifestyle Intervention (LI-PAD-Extended)
The goal of this clinical trial is to learn if an individualized lifestyle intervention works to improve weight, diet, physical activity, cardiovascular health, health-related quality of life, and cost-effectiveness in overweight…
- Conditions
- Overweight, Obesity, Prediabetic State
- Trial name
- LI-PAD-EXTENDE (NCT07605169)
- Testing
- Individualized physical activity and diet
- Where
- Sweden
- Volunteers
- 103 people
- Sponsor
- Vastra Gotaland Region
Osteoporotic Vertebral Compression Fractures
Cost Effectiveness and Efficacy of Kyphoplasty and Vertebroplasty Trial
Randomized trial comparing cost effectiveness and efficacy of kyphoplasty vs vertebroplasty for the treatment of painful, osteoporotic vertebral compression fractures.
- Trial name
- NCT00279877
- Testing
- Kyphoplasty
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of Virginia
Dementia
Comparative Effectiveness of Dementia Care Strategies in Underserved Communities
Dementia is a condition that is growing in prevalence and which harms not only the afflicted individual but also adversely affects the health of their family and other informal caregivers.
- Trial name
- NCT01459783
- Testing
- Dementia care management
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- RAND
Pregnancy
Safety and Cost-Effectiveness of Early Maternal Newborn Infant Discharge
To determine the effect of a policy of early maternal-newborn infant discharge (12-24 hours) with a home visit on admission to the Level II/III nursery and hospital admissions and readmissions.
- Trial name
- NCT02372266
- Testing
- Early Maternal-Newborn Infant Discharge, Routine discharge
- Volunteers
- 2,223 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
POSTOPERATIVE PAIN
Comparative Study of Two Different Techniques to Perform TAP-blocks
The TAP is a space between the muscle layers of the abdominal wall that houses nerves supplying the abdominal skin. Injecting the local anesthetic ropivacaine into this space will block these nerves and prevent pain following…
- Trial name
- Surgical-TAP (NCT02571439)
- Testing
- Surgical TAP block, Conventional TAP block, 0.5% ropivacaine
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Maimonides Medical Center
Sleep Apnea, Obstructive
Portable Monitoring for Diagnosis and Management of Sleep Apnea
This multi-site project compares compares the efficiency of a home-based portable monitoring strategy to a standard of care sleep laboratory-based strategy for the diagnosis and positive airway pressure treatment of obstructive…
- Trial name
- HomePAP (NCT00642486)
- Testing
- Portable (Embla Embletta X30 system and Respironic REMStar Auto M series with CFlex), Standard polysomnography (PSG)
- Where
- United States
- Volunteers
- 373 people
- Sponsor
- Case Western Reserve University
Infectious Gastroenteritis
Stool Testing With Molecular Assay to Minimize Contact Precautions
This study evaluates the impact of infectious diseases molecular-based stool testing compared to conventional stool testing on reducing the need for contact precautions among hospitalized patients.
- Trial name
- NCT04189874
- Testing
- Conventional Stool Testing, BioFire FilmArray Gastrointestinal Panel
- Where
- Canada
- Volunteers
- 156 people
- Sponsor
- Giulio DiDiodato
Insomnia
Stepped Care Model for the Wider Dissemination of Cognitive-Behavioural Therapy for Insomnia Among Cancer Patients
Insomnia is very common in cancer patients. When left untreated, insomnia can lead to numerous serious consequences (e.g., psychological disorders) for the individual and significant costs for society (e.g., increased medical…
- Trial name
- Stepped Care (NCT01864720)
- Testing
- Professionally-administered cognitive-behavioral therapy for insomnia (CBT-I), Web-based cognitive-behavioral therapy for insomnia (CBT-I)
- Where
- Canada
- Volunteers
- 177 people
- Sponsor
- CHU de Quebec-Universite Laval
Sustainability
Sustainability of Laparoscopic Appendectomy. Variability of Determining Factors.
Today, evidence shows that environmental changes significantly affect human health. The healthcare sector itself is a major emitter of environmental pollutants. It is responsible for 4-5% of global greenhouse gas emissions.
- Trial name
- NCT07457853
- Where
- Chile
- Volunteers
- 63 people
- Sponsor
- Universidad de La Frontera
Diabetes Mellitus, Type 1
Telemedicine Program in Type 1 Diabetes and CSII
Diabetes mellitus is a chronic disease of high socio-health relevance for their clinical and economic implications (risk of complications, disability ...) (healthcare costs).
- Trial name
- NCT02790645
- Testing
- Group 2a. Telemedicine program, Group 1a. Control, Group 1b.Telemedicine program
- Volunteers
- 51 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Low Back Pain
Cost- Effectiveness of a Face-to-Face Rehabilitation Program vs an Telemedicine Program in Chronic Low Back Pain
Perform a cost-utility analysis in patients with chronic low back pain through electroanalgesia treatment and exercises administered by telemedicine program versus face-to-face program
- Trial name
- NCT04266366
- Testing
- Face-to-Face Rehabilitation program, Telemedicine program
- Where
- Spain
- Volunteers
- 540 people
- Sponsor
- Universidad de Almeria
Control - No Incentive for Flu Vaccine, Direct Incentive
Non-integrated Costs Increase Effectiveness of Incentives
The investigators will test the hypothesis that the control (no incentive) condition will have the lowest vaccination rate, the main task condition will have a significantly higher vaccination rate while the indirect condition…
- Conditions
- Control - No Incentive for Flu Vaccine, Direct Incentive, Indirect Incentive
- Trial name
- NCT03507231
- Testing
- Email Message, Incentive for Vaccination, Incentive for completing a short survey
- Where
- United States
- Volunteers
- 12,531 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Psychotic Disorders
Improving Heart and Metabolic Health in People With Severe Mental Illness Through a Long-term Clinical Trial
Background Cardiometabolic conditions-including cardiovascular disease, type 2 diabetes, and obesity-are highly prevalent among individuals with psychotic disorders.
- Trial name
- LAGOM (NCT06781801)
- Testing
- Intervention
- Where
- 6 sites in Sweden
- Volunteers
- 650 people
- Sponsor
- Vastra Gotaland Region
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