Clinical trials: Diagnoses Diseases
Osteoarthitis, Osteoporosis
Evaluation of Musculoskeletal Aging and Related Disorders Via Advanced Clinical Imaging
Study Overview This clinical research focuses on the development and validation of a multimodal artificial intelligence (AI) platform designed for the automated diagnosis and precise staging of two major musculoskeletal…
- Trial name
- NCT07474571
- Testing
- No Interventions
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Tuberculosis, Pulmonary
Integrated Discovery and Development of Innovative TB Diagnostics
The long term goal of this project is to provide information critical to the development and use of a low-cost, point-of-care, rapid, simple, and highly accurate diagnostic tool that can help clinicians make a microbiological…
- Trial name
- (CETR) (NCT06624501)
- Testing
- Observational cohort study
- Volunteers
- 1,450 people, healthy volunteers welcome
- Sponsor
- Harvard University Faculty of Medicine
Vaccines, Adverse Effects, Injection Site Reaction
Evaluation of Deltoid Exercises on Injection Site Pain After (BNT162b2) COVID - 19 Vaccination
Pfizer - BioNTech (BNT162b2) COVID - 19 vaccine is the first vaccine to be approved for emergency use by FDA. The most commonly reported side effect of the BNT162b2 vaccination is mild-to-moderate pain at injection site, i.e.
- Trial name
- NCT05157230
- Testing
- exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Asthma
A Trial Evaluating Novel Technologies for the Diagnosis of Asthma The LUNG-TECH Trial
This trial aims to evaluate novel diagnostic technologies for asthma in 3 different pathways providing the necessary evidence-base to allow adoption into clinical practice: Pathway 1 evaluates whether the technology can…
- Trial name
- LUNG-Tech (NCT05819944)
- Where
- United Kingdom
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Neurodevelopmental Disorder (Diagnosis)
Virtual Reality Headset as an Alternative Tool for Reducing Dental Anxiety
The aim of this study is to investigate whether the use of virtual reality (VR) headsets can have a positive effect on dental fear during dental procedures and stress induced by the dental environment.
- Trial name
- NCT07667023
- Testing
- Virtual reality headset, standard dental care
- Where
- Hungary
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Cystic Fibrosis
Small Circulating RNA as Molecular Markers of Lung Disease in Cystic Fibrosis
The aim of our study is to assess miRNAs expression profiles in the circuling blood of patients with cystic fibrosis and highlight "signatures" that could reflect the pulmonary status of patients
- Trial name
- MIRDIAMUCO (NCT02992080)
- Testing
- miRNAs isolation from blood samples of patients and control
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Hypertension, Hypertensive Heart Disease
E_Stethoscope: Portable Digital Auscultation Study on Hypertensive/Hypertensive Heart Disease Patients
Hypertensive heart disease (HHD) is a heart condition that is caused by chronic exposure to high blood pressure. In patients with HHD, abnormalities in the way heart muscle relaxes and how heart chambers passively fill with blood…
- Trial name
- NCT02809040
- Testing
- Electrocardiogram/Echocardiography, Portable digital auscultation
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Deglutition Disorders
A New Ultrasound Score for Swallowing Disorders Diagnosis in Difficult-to-wean Tracheostomised Patients
Swallowing Disorders (SD) is commonly observed in intensive care unit (ICU) patients. Disruption to the upper airway by way of a tracheostomy may lead to physiological and/or biomechanical changes to the swallow, thereby…
- Trial name
- SHUBACA (NCT06630013)
- Where
- 4 sites in France
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Hopital Forcilles
Dual Diagnosis, Alcohol Use Disorder
The 15-Mental Project: Implementation and Evaluation of the 15-Mental in a Mental Health Hospital Setting
The present project will implement and evaluate the effectiveness of a novel, but simple model for addressing and treating alcohol problems among patients admitted to outpatient treatment at mental health hospitals, called the…
- Conditions
- Dual Diagnosis, Alcohol Use Disorder, Hazardous Alcohol Use, Screening and Brief Intervention
- Trial name
- NCT07728968
- Testing
- 15-Mental.
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Healthy
Capsaicin-induced Muscle Pain in Humans
There is currently no specific diagnostic test for primary muscular pain. The present study investigates whether selective blockade of the suprascapular nerve can effectively abolish experimental pain arising from the…
- Trial name
- NCT02377180
- Testing
- Intramuscular capsaicin injection, Suprascapular nerve block, Local anesthetic infiltration
- Where
- Switzerland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Chronic Kidney Disease
Depressed Cardiac Autonomic Modulation in Patients With Chronic Kidney Disease Diagnosed by Spectral Analysis
Background/Aims: To evaluate the sympathovagal balance in patients with chronic kidney disease (CKD) on conservative treatment. Methods: In a cross-sectional study, patients with CKD stages 3, 4 and 5 not yet on dialysis (CKD…
- Trial name
- HRV (NCT01376635)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Core Educational Research and Treatment in Nephrology
Stomach Neoplasms, Metaplasia
Acetic Acid Chromoendoscopy to Judge Gastric Intestinal Metaplasia
The presence and the extent of gastric intestinal metaplasia(IM) is a good indicator of high risk group of gastric cancer. Many methods was developed to survey it, including multiple gastric biopsy or methylene blue…
- Trial name
- IM (NCT01499576)
- Testing
- Acetic acid chromoendoscopy
- Where
- South Korea
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Konyang University Hospital
Hepatitis B, Healthy
Preliminary Validation of an in Vitro Diagnosis-medical Device for Hepatitis B Screening
The principal objective of the study is to perform a first step of technical adjustment and preliminary validation of a diagnostic test for hepatitis B (HBsAntigen, anti-HBs Antibody and anti-HBc Antibody) on capillary blood with…
- Conditions
- Hepatitis B, Healthy, Diagnoses Disease
- Trial name
- DiVHeB (NCT04109625)
- Testing
- Demonstrator MAGIA
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
MicroRNAs, Colorectal Cancer
Serum MicroRNAs as Diagnostic Biomarkers of Colorectal Cancer
evaluation the diagnostic value of certain MicroRNAs as biomarkers of Colorectal cancer by comparing its expression levels in Colorectal cancer patients and normal individuals.
- Conditions
- MicroRNAs, Colorectal Cancer, miR-15b, miR-21
- Trial name
- NCT06738225
- Testing
- certain serum MicroRNA biomarkers (miR-15b and miR-21)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Bishoy Shehata
Asthma, COPD
Asthma, Inflammation and G Protein-coupled Receptors (GPCR)
The G protein-coupled receptors (GPCRs) are a family of proteins expressed at the cell membrane. They are composed of 380 members involved in the important functions of the organism and are privileged therapeutic targets.Their…
- Trial name
- NCT00793676
- Testing
- spirometry, blood test
- Where
- 5 sites in France
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Healthy Volunteers, Relative Afferent Pupil Defect
The PUPIL Study - Automated, Quantitative Pupil Assessment Using Binocular OCT
In current, clinical ophthalmology, a range of specialised testing allows comprehensive evaluation of ocular health. These tests have typically evolved over many years to ensure their clinical validity.
- Conditions
- Healthy Volunteers, Relative Afferent Pupil Defect, Pupil Anomaly
- Trial name
- NCT03081468
- Testing
- Binocular OCT prototype, Konan RAPDx
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University College, London
Diagnosis
Echocardiographic Standards and Sub-Saharian Africans (SSA) Migrants' in New Aquitaine Region
Standards Echocardiographic have been defined mainly on caucasian or Asian populations. In the EchoNoRMAL study the criteria for African populations were based solely on data from 198 subjects.
- Trial name
- NEMANA (NCT04865068)
- Testing
- Echocardiography measures on SSA participants
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Liver Fibrosis
Development of Non-Invasive MRI Applications for Liver Fibrosis and Inflammation
Chronic liver disease is a major healthcare problem in Hong Kong and worldwide. The diagnosis of liver fibrosis and inflammation in patients with chronic liver disease has important prognostic and therapeutic implications.
- Trial name
- NCT05168982
- Where
- Hong Kong
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
SARS-CoV2 Infection, COVID-19
BinaxNOW for Evaluating Children for Infection With SARS-CoV-2 (COVID-19)
This is a study of the BinaxNOW Covid-19 Ag Card as a method to rapidly identify SARS-CoV-2 infection in asymptomatic children, teachers, and other school staff for exclusion.
- Trial name
- NCT05087524
- Testing
- BinaxNOW Ag Card
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Thoracic Diseases
Evaluating a Text-Prompt AI Assistant for Chest CT Scans (AI-REPORT Study)
This study aims to find out if an artificial intelligence (AI) system can help experienced radiologists write chest CT scan reports more quickly without lowering the quality of the report.
- Trial name
- AI-REPORT (NCT07634861)
- Testing
- AI-generated report for chest CT, Standard reporting procedure (no AI assistance)
- Where
- 2 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
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