Clinical trials: Diet Interventions
Familial Hypercholesterolemia
Soy Food Intervention Trial
Familial hypercholesterolemia (FH MIM#143890), an inherited disorder of lipoprotein metabolism, is a risk for early cardiovascular disease (CVD).
- Trial name
- SOYFIT (NCT00924339)
- Testing
- soy protein diet, rapeseed oil
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Obesity
Team PLAY (Positive Lifestyles for Active Youngsters)
The purpose of this study is to determine whether an intense family-centered program to help children, 4 to 7 years old, control their weight is more effective than the advise and referrals their health provider gives in the…
- Trial name
- Team PLAY (NCT00528164)
- Testing
- Team PLAY
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Female
Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes
The goal of this clinical trial is to determine the effectiveness of using a freeze-dried wild blueberry powder on cardiometabolic health, cognitive function, and gut microbiota composition in adult women with prediabetes.
- Conditions
- Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Female, Adult, Endothelial Function (Reactive Hyperemia)
- Trial name
- NCT06735651
- Testing
- Wild Blueberry
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Georgia State University
Healthy Lifestyle, Physical Exercise
Lifestyle and Brain Vascular Function
Cognitive performance is negatively related to an impaired glucose metabolism, possibly due to impairments in brain vascular function.
- Conditions
- Healthy Lifestyle, Physical Exercise, Healthy Diet, Cerebrovascular Circulation
- Trial name
- NCT04234009
- Testing
- Healthy Lifestyle
- Where
- Netherlands
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obesity & Overweight, Cardiometabolic Risk Factors
Pilot Test of Five Weight Neutral Interventions to Improve Health Among Adults of Higher Body Weight
The purpose of this research study is to pilot test five different, group based and remotely delivered programs designed to support healthy eating and regular physical activity.
- Trial name
- NEW PATH (NCT07363616)
- Testing
- Mediterranean eating style, Physical activity, Mindful Eating
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Obesity
Nutrition Intervention and Play Group Exercise for Low-income Latinas
Obesity among Mexican-American women has the potential to become a public health crisis. Hispanics are one of the fastest growing minority populations in the United States and the prevalence of obesity in Mexican American woman…
- Trial name
- CHICOS (NCT00454948)
- Testing
- Home-based nutrition sessions and play group exercise, Group-based nutrition sessions and mail-out activities
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Stanford University
Overweight, Obesity
Empowering Consumers to 'PREVENT' Diet-related Diseases Through 'OMICS' Sciences
The over-all aim of this 10-week randomized-controlled study, taking place only in Denmark, is to examine whether the PREVENTOMICS platform integrated in an e-commerce digital tool created to deliver personalized meals and…
- Conditions
- Overweight, Obesity, Metabolic Syndrome
- Trial name
- PREVENTOMICS (NCT04590989)
- Testing
- Personalized Nutrition Plan, Non-Personalized Nutrition Plan
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Mediterranean Diet, Overweight or Obese Adults
ENERGY2MOB STUDY: OBESITY MANAGEMENT IN BERGUEDÀ
Background: Obesity is a prevalent multifactorial disease worldwide and has become a significant public health concern. The latest data from the 2022 Catalonia Health Survey show that 56.2% of men and 43.7% of women are…
- Conditions
- Mediterranean Diet, Overweight or Obese Adults, Exercise Therapy, Cardiovascular Diseases
- Trial name
- ENERGY2MOB (NCT06988904)
- Testing
- Energy2MOB
- Where
- Spain
- Volunteers
- 136 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Cardiovascular Disease
Dietary Intervention and Vascular Function
It is well established that diet plays an important role in both the development and progression of heart disease. Different types of dietary fat have varying effects on heart disease risk factors.
- Trial name
- DIVAS (NCT01478958)
- Testing
- SFA diet, MUFA diet, n-6 PUFA diet
- Where
- 2 sites in United Kingdom
- Volunteers
- 202 people
- Sponsor
- University of Reading
Spondyloarthritis, Rheumatoid Arthritis
Nutrition in Rheumatic Diseases
Background: Patients with inflammatory rheumatic diseases (IRD) are prone to malnutrition for several reasons. The diseases and treatment can cause reduced intake and absorption of nutrients and the inflammatory processes may…
- Conditions
- Spondyloarthritis, Rheumatoid Arthritis, Polyarthritis
- Trial name
- EROM (NCT04586933)
- Testing
- Omega-3, Dietary guidance
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Haukeland University Hospital
Sedentary Lifestyle, Sedentary Behavior
Kids FIRST: Family-based Intervention to Reduce Snacking and Screen Time in Children
Kids FIRST was a 12-week, four arm, home- and school-based pilot randomised controlled trial to reduce screen-time and unhealthy snacking with assessments at pre- (baseline) and post-intervention.
- Conditions
- Sedentary Lifestyle, Sedentary Behavior, Diet Habit
- Trial name
- NCT03993652
- Testing
- Kids FIRST
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Diet, Food, and Nutrition, Healthy Eating
Mitigating and Preventing Disordered Eating in Transitioning Service Members
Despite documented evidence of disordered eating (DE) among Active Duty (AD) Service Members (SM) and Veterans, DE has not been assessed in SM undergoing the transition from AD to Veterans status (AD-VS).
- Conditions
- Diet, Food, and Nutrition, Healthy Eating, Eating Habit, Mindfulness
- Trial name
- NCT05074108
- Testing
- Pilot study
- Volunteers
- healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Obesity, Overweight
Remotely Delivered Behavioral Weight Loss Using an Ad Libitum Plant-Based Diet Versus a Balanced Calorie Deficit Diet
This pilot randomized controlled trial will compare a remotely delivered behavioral weight loss program with a balanced calorie deficit diet (the current gold-standard) to a behavioral weight loss program with an ad libitum whole…
- Trial name
- NCT05337150
- Testing
- Lifestyle Modification Intervention, Balanced Calorie Deficit Eating Plan, Ad Libitum Whole Food Plant-Based Eating Plan
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Drexel University
Obesity, Pregnancy
CO-OP Trial: Community-based Outreach on Obesity in Pregnancy
Obesity is becoming more common and disproportionately affects the younger generation, the poor and certain ethnic groups. Nearly 50% of reproductive aged women are obese or overweight.
- Trial name
- CO-OP (NCT01841424)
- Testing
- Dietary counseling. Maintain a food diary.
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Eosinophilic Esophagitis, Eosinophilic Gastrointestinal Disorders (EGIDs)
Eosinophilic Esophagitis Intervention Trial-1 Food vs. 4 Food Elimination Diet Followed by Swallowed Glucocorticoids
The purpose of this interventional study is to test and compare the effectiveness of two elimination diets-the 1-food elimination diet (1FED, milk only) and the 4-food elimination diet (4FED, milk, egg, wheat, and soy) for…
- Trial name
- NCT02610816
- Testing
- 1 Food Elimination Diet, 4 Food Elimination Diet, 4 Food Elimination Diet (post 1FED failure)
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Obesity, Type 2 Diabetes
A Specialized Diet for the Unique Metabolic Characteristics of Peripubertal African American Girls
A diet (42% carbohydrate) specialized to the unique metabolic characteristics of peripubertal African AMerican girls (hyperinsulinemic, low insulin sensitive) will be more effective in maintaining glucose and insulin homeostasis…
- Trial name
- PRIMO (NCT00718874)
- Testing
- Dietary
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Osteoarthritis
Patient and Provider Interventions for Managing Osteoarthritis in Primary Care
Osteoarthritis (OA) is one of the most common chronic conditions and a leading cause of pain and disability among adults. Many adults with OA have significant pain and functional limitations, even though they receive some medical…
- Trial name
- PRIMO (NCT01435109)
- Testing
- Patient Behavioral Intervention for OA, Provider Intervention for OA, Combined Patient and Provider Interventions for OA
- Where
- United States
- Volunteers
- 537 people
- Sponsor
- Duke University
Head and Neck Cancer
Diet Intervention, Head and Neck Cancer, Feasibility
This study will examine the effects of a dietary intervention in post-treatment head and neck cancer survivors on the ability to function physically, tiredness, and quality of life, as well as on changing markers in the blood…
- Trial name
- NCT03013699
- Testing
- Cruciferous and Dark Leafy Green Intervention, Usual Dietary Care
- Volunteers
- 23 people
- Sponsor
- University of Alabama at Birmingham
Breast Cancer
Anti-Inflammatory Diet in BRC Patients on Aromatase Inhibitors
This project aims to decrease undesirable side effects and increase qulaity of life of aromatase inhibitors therapy in breast cancer survivors, by anti-inflammatory diet or supplementation.
- Trial name
- AID (NCT06214598)
- Testing
- Supplement, AI diet
- Where
- 2 sites in Serbia
- Volunteers
- 90 people
- Sponsor
- University of Belgrade
Obesity, Dietary Intervention
Effects of Boron and Mediterranean Diets on Gut Microbiota and Metabolic Health
This study investigated the effects of a boron-rich diet compared with a Mediterranean-style diet (Smart Alternative Food Formulation; SAFF) on obesity-related outcomes in adults.
- Conditions
- Obesity, Dietary Intervention, Gut Microbiota, Cardiometabolic Risk Factors
- Trial name
- BOR-SAFF (NCT07156097)
- Testing
- Mediterranean-style Diet (SAFF), Boron-rich Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dicle University
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