Clinical trials: EUS
Gastric Varices Bleeding
EUS Guided Coil Embolization for Primary Prophylaxis of Gastric Varices
The standard treatment of bleeding gastric varices is obliteration with placement of coil and glue. Our study will evaluate the efficacy of EUS guided coil as primary prophylaxis for high-risk gastric varices.
- Trial name
- EUS (NCT06370169)
- Testing
- Endoscopic ultrasound placement of Coil and glue
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Asian Institute of Gastroenterology, India
Chronic Pancreatitis
Correlation of Chronic Pancreatitis Pathology Features With Endoscopic Ultrasound (EUS) Criteria
In this research project the investigators intend to find out if Endoscopic Ultrasound (EUS) criteria for diagnosing chronic pancreatitis can be correlated with pathologic characteristics of tissues taken from pancreas of…
- Trial name
- NCT01442441
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Indiana University
Choledocholithiasis
To Compare EUS and MRCP in Detecting Choledocholithiasis in Patients of Intermediate Risk of Choledocholithiasis
A Recent Meta analysis, showed pooled sensitivity and specificity were 97% and 90 for EUS and 87% and 92 for MRCP . This meta analysis includes only 5 studies, smaller sample size in each study, significant heterogeneity in…
- Trial name
- NCT04173624
- Testing
- Endosonography, Magnetic Resonance Cholangiopancreatography
- Where
- India
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Gastric Varices Bleeding
Efficacy and Safety of Contrast EUS-Guided Tissue Glue/Coil Devascularization vs. BRTO for Preventing Recurrent Gastric Variceal Bleeding
The goal of this clinical trial is to compare the effectiveness of EUS-guided tissue glue/coil injection and BRTO in preventing rebleeding of gastric varices (GVs) in patients with portal hypertension and GVs (including those…
- Trial name
- NCT07049146
- Testing
- EUS-guided tissue glue/coil injection, BRTO
- Where
- China
- Volunteers
- 242 people
- Sponsor
- West China Hospital
Pancreatic Neoplasms, Mediastinal Neoplasms
22G-Adapt Needle Biopsy Versus Fine-needle Aspiration in Endoscopic Ultrasound-guided Sampling of Solid Lesions
The investigators conduct a multicenter randomized controlled study to evaluate the diagnostic value and safety of 22G Adapt Aspiration puncture needle for histopathology of solid lesions.
- Conditions
- Pancreatic Neoplasms, Mediastinal Neoplasms, Abdominal Neoplasm, Excluding Pancreas Neoplasm
- Trial name
- NCT06563232
- Testing
- FNA group, Adapt FNB group
- Where
- China
- Volunteers
- 656 people
- Sponsor
- Huazhong University of Science and Technology
Lung Cancer
Mediastinal Staging of Lung Cancer With EBUS-TBNA and EUS-B-FNA
The purpose of this study is to find a role of EUS-B-FNA in the mediastinal staging of potentially operable lung cancer. The investigators perform EBUS-TBNA and EUS-B-FNA on potentially operable lung cancer patients.
- Trial name
- NCT00741247
- Testing
- EBUS-TBNA, EUS-B-FNA (EUS-FNA with bronchoscope)
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- National Cancer Center, Korea
Calculi, Stenosis of Bile Duct
EUS Prior to ERCP in the Positive Setting of Positive Intraoperative Cholangiogram (IOC) During Cholecystectomy
Performing an EUS prior to ERCP in the setting of a positive intraoperative cholangiogram will identify and risk stratify patients for the presence of CBD stones and strictures.
- Trial name
- NCT01525355
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Pancreatic Cancer, Pain
Evaluation of Injection Techniques in Celiac Plexus Neurolysis
1. To evaluate the efficacy of EUS-CPN in subjects who experience a sympathetic response during injection when compared with subjects who do not experience sympathetic response during injection.
- Trial name
- NCT02068677
- Testing
- Sympathetic response, no sympathetic response
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- AdventHealth
Pancreatic Neoplasms
Diagnostic Yield of 20-gauge Procore Needle for EUS-guided FNA Biopsy in Solid Pancreatic Lesions
This study aims to examine technical feasibility and diagnostic yield of new 20-gauge Procore needle for EUS-guided fine needle biopsy in solid lesions by comparing with 22-gauge Procore needle.
- Trial name
- NCT02920944
- Testing
- EUS-FNB with 20 gauge ProCore needle, EUS-FNB with 22 gauge ProCore needle
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Seung Bae Yoon
Pancreas Cancer, Pancreatic Adenocarcinoma
Study Comparing Pancreatic EUS-FNB With the 20-gauge Procore® and the 22-gauge Acquire® Needles
Multicenter randomized prospective study Criteria for inclusion: Patients admitted for EUS-FNB of a pancreatic mass Goals of the study: To compare the results of blinded punctures for suspicion of pancreatic tumor performed under…
- Trial name
- HISTOPAN (NCT03567863)
- Testing
- 20-GAUGE PROCORE® first, then 22-GAUGE ACQUIRE®, 22-GAUGE ACQUIRE® first, then 20-GAUGE PROCORE®
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Société Française d'Endoscopie Digestive
Liver Cirrhosis, Liver Diseases
Endoscopic Ultrasound-Guided Portosystemic Pressure Gradient Measurements
The objective of the study is to collect and report technical success of direct endoscopic ultrasound guided hepatic and portal vein pressure measurement obtained with EchoTip® Insight™ in patients with cirrhosis who are referred…
- Conditions
- Liver Cirrhosis, Liver Diseases, Hypertension, Portal
- Trial name
- NCT04668664
- Testing
- EchoTip® Insight™ Portosystemic Pressure Gradient Measurement System (EchoTip® Insight™)
- Where
- 7 sites in United States, Australia and 1 more
- Volunteers
- 70 people
- Sponsor
- Cook Research Incorporated
Pancreatic Neoplasms, CHRONIC PANCREATITIS
Needle-based Confocal Endomicroscopy Examination of Pancreatic Masse
Introduction: Pancreatic cancer is one of the most aggressive malignancies with only 5% of patients being alive at five years. EUS (endoscopic ultra sound) is an established, sensitive diagnostic tool in pancreatic cancer and for…
- Trial name
- NCT01734967
- Testing
- needle based CLE, EUS-FNA
- Where
- 2 sites in Denmark, Romania
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Pancreas Adenocarcinoma, Endoscopic Ultrasound
Digital Confocal Microscopy for Real-time Diagnosis of Pancreatic Solid Lesion
Endoscopic ultrasound-guided (EUS) tissue acquisition is the current standard of care for the diagnosis of pancreatic solid lesions but it is burdened by a non-negligible risk of non-diagnostic or inconclusive results.
- Conditions
- Pancreas Adenocarcinoma, Endoscopic Ultrasound, Digital Pathology
- Trial name
- Multi-RELAMI (NCT06315439)
- Testing
- Endoscopic ultrasound fine needle biopsy
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Campus Bio-Medico University
Pancreatic Carcinoma Metastatic, Pancreatic Adenocarcinoma
Trial Comparing EUS-guided Radiofrequency Ablation vs. EUS-guided Celiac Plexus Neurolysis
Pancreatic cancer is the second most common gastrointestinal malignancy. Abdominal discomfort is a main symptom in patients with pancreatic cancer. Approximately 75% have pain at diagnosis and over 90% in advanced stages.
- Conditions
- Pancreatic Carcinoma Metastatic, Pancreatic Adenocarcinoma, Pancreatic Neoplasms, Pancreatic Cancer
- Trial name
- NCT03152487
- Testing
- Celiac Plexus Neurolysis, Radiofrequency Ablation
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- AdventHealth
Subepithelial Gastrointestinal Tumors
SUNNYDAY: SUbepithelialgastroiNtestiNal Tumors Detection,accuracYDiAgnosis,ElastographY and Contrast-enhanced EUS
This will be a longitudinal, prospective, observational multicenter study where the role of EUS-E will be examined in differentiating subepithelial gastrointestinal tumors in 138 patients
- Trial name
- SunnyDay021 (NCT06324032)
- Testing
- EUS Elastography (EUS-E)
- Where
- 7 sites in Italy
- Volunteers
- 138 people
- Sponsor
- Fondazione del Piemonte per l'Oncologia
Pancreatitis, Acute Necrotizing
Strategic Timing of Endoscopic Interventions in Infected Necrotizing Pancreatitis
Pancreatic necrosis complicates approximately 20-30% of severe acute pancreatitis cases. While many collections resolve without intervention, persistent symptomatic collections-particularly when infected-are associated with…
- Trial name
- STEP-IN (NCT07406698)
- Testing
- EUS-guided transluminal drainage of necrotic collection
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Orlando Health, Inc.
Liver Cirrhosis
Comparison of Pre-operative EUS Guided and Intra-operative Direct Portal Vein Pressure Measurement in Pretransplant Cirrhotics
Direct portal pressure measurement under EUS-guidance (EUS-PPM) is a promising alternative to conventional indirect Hepatic Venous Pressure Gradient (HVPG).
- Trial name
- NCT06114355
- Testing
- EUS Portal pressure measurement
- Volunteers
- 25 people
- Sponsor
- Asian Institute of Gastroenterology, India
Esophageal Cancer
Endoscopic Ultrasound Plus Submucosal Injection for Early Esophageal Cancer
Preoperative accurately staging T1a or T1b in early esophageal cancer is vital for the choices of treatment. At present, the main diagnostic method for early esophageal cancer is endoscopic ultrasound (EUS).
- Trial name
- NCT01555801
- Testing
- submucosal injection needle ; EUS, ordinary endosonography(EUS)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sun Yat-sen University
Efficacy of Endoscopic Ultrasound Guided Liver Biopsy Using Dynamic Wet Technique
Efficacy of Endoscopic Ultrasound Guided Liver Biopsy Using Dynamic Wet Technique
Endoscopic ultrasound-guided liver biopsy (EUS-LB) can overcome many shortcomings of percutaneous liver biopsy and TJLB. Targeted and non-targeted liver biopsies can be done through this biopsy.
- Trial name
- NCT06833619
- Testing
- Efficacy of Endoscopic Ultrasound Guided Liver Biopsy Using Dynamic Wet Technique
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Pancreatic Cyst
New Biomarkers in the Intracystic Liquid of Inflammatory and Non-inflammatory Pancreatic Cysts
Due to the advances made in the field of the imaging techniques and their common use, pancreatic cysts are more and more incidentally found.
- Trial name
- NCT05568433
- Testing
- Endoscopic ultrasound fine needle aspiration (EUS-FNA)
- Where
- Romania
- Volunteers
- 63 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy