Clinical trials: Effect Increased
Smoking
Effects of Quitting Study A Test of Pre-clinical Findings
The most widely-accepted animal model of nicotine withdrawal states stopping nicotine makes rewarding events become less rewarding. The current study will test if this is true in humans.
- Trial name
- NCT01824511
- Testing
- Smokers cease smoking
- Where
- 2 sites in United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Anesthesia, Local
Does Perineural Dexamethasone Increase the Duration of an Ulnar Nerve Block When Controlling for Systemic Effects?
Investigators will assess if perineural dexamethasone can increase the duration of an ulnar nerve block when controlling for systemic effects in healthy volunteers.
- Trial name
- NCT04817982
- Testing
- Perineural dexamethasone, Lidocaine, Systemic dexamethasone
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Chronic Kidney Disease
Effects of a Reduction in Kidney Function on Cardiovascular Structure and Function: A Prospective Study of Kidney Donors
Studies of patients with established kidney disease, even when this is mild, appear to show that they are at high risk of heart failure, stroke and sudden cardiac death.
- Trial name
- NCT01028703
- Where
- United Kingdom
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Blood Pressure
Placebo Effects on Blood Pressure
A relevant reduction of blood pressure (BP) in placebo-treated control groups is a phenomenon often observed in pharmacological studies of hypertension.
- Trial name
- NCT00570271
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Periodontitis
Effects of Azithromycin as an Adjunct to Scaling and Root Planning in the Treatment of Periodontitis
The growing interest in the possibilities of modulating macrophages in inflammatory diseases with therapeutic purpose has prompted the development of new approaches for the treatment of periodontitis.
- Trial name
- NCT05506371
- Testing
- Az+SRP, SRP, No interventions
- Where
- Ukraine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ukrainian Medical Stomatological Academy
Cerebral Palsy, Spastic
Effect of Task-Specific Training in an Augmented Reality Context on Upper Limb Function and Activities in Children With Spastic Cerebral Palsy
Children with Cerebral Palsy (CP), a condition that affects movement and coordination, face difficulties in daily activities such as dressing, reaching for objects in high places, and getting up from seats.
- Trial name
- INTERACT (NCT06571929)
- Testing
- INTERACT
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Clinical Trial
Effect of Increased Improve Time on Adhesive System
Objective: This double-blind randomized clinical trial evaluates the influence of increased application time of a new etch-and-rinse two-step adhesive Single Link; (Angelus Dental Products Industry) applied in non-carious…
- Trial name
- RCT (NCT03254706)
- Testing
- Peak etch-and-rinse (P1), Peak applied for double time(P2X), Single Link etch-and-rinse (SL1)
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Ponta Grossa
Healthy Older Adults, Healthy Young Adults
Effects of Feedback and Aging on Aiming Movements in Virtual Reality
This study has two main objectives: First, to better understand how a motor task commonly used by researchers, known as the Fitts' task, is performed in virtual reality.
- Trial name
- NCT07435506
- Testing
- VR-augmented specific feedback, VR-augmented global feedback, R-intrinsic feedback
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aix Marseille Université
Focus of Study Instead
Endometrial Injury Increases Implantation and Pregnancy Rates
Objective To evaluate the effect of local injury to the endometrium for implantation, pregnancy and live birth rates in ICSI -ET cycles with recurrent implantation failure. Design Randomized controlled clinical study.
- Trial name
- NCT01340560
- Testing
- Endometrial biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Performance Enhancement, Athlete
Augmented Feedback Effects on Shoulder Rotator Performance
The existing literature demonstrates that motor learning strategies are effective in enhancing sports performance. One of these strategies, augmented feedback, is widely used in athletic training to help athletes achieve their…
- Conditions
- Performance Enhancement, Athlete, Shoulder
- Trial name
- NCT07510893
- Testing
- Augmented Feedback
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Elif Turgut
Gastroesophageal Disease
To Determine if Sleep Deprivation Results in Increased Esophageal Acid Exposure
The purpose of this study is to determine if sleep deprivation results in increased esophageal acid exposure in healthy controls and gastroesophageal reflux disease (GERD) patients.
- Trial name
- IRUSESOM0428 (NCT01093339)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Southern Arizona VA Health Care System
Dehydrated, Water-Electrolyte Imbalance, Malnutrition, Dehydration (Physiology)
Effects of Increased Water Intake on Hormonal Response, Hydration Status, and Physical Function in Low-drinking Older Adults
DrinkAge is a randomized controlled trial investigating whether increasing daily water intake can improve hydration and health-related outcomes in adults aged 60 years or older who habitually drink relatively little water.
- Trial name
- DrinkAge (NCT07892742)
- Testing
- Water
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Polytechnic University of Santarém
Food Consumption
Can Calorie Labels Increase Caloric Intake
This study is a test of possible mechanisms by which calorie labels might lead people to increase calorie intake. The investigators hypothesize that calorie labels might increase calorie intake because 1) people infer that higher…
- Trial name
- NCT01473225
- Testing
- Calorie information, No calorie information
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Vitamin D Deficiency, Chemotherapy Effect
Vitamin D Can Increase Pathological Response of the Breast Cancer Patients Treated With Neoadjuvant Therapy
The aim of the study is to evaluate the relationship between the vitamin D replacement and pathological response in patients undergoing neoadjuvant therapy according to different molecular sub types.
- Conditions
- Vitamin D Deficiency, Chemotherapy Effect, Pathology
- Trial name
- NCT03986268
- Testing
- Vit D
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Florence Nightingale Hospital, Istanbul
Aging, Sarcopenia
Peanut Protein Supplementation to Augment Muscle Growth and Improve Markers of Muscle Quality and Health in Older Adults
This study will evaluate the adaptations in skeletal muscle that occur in response to 10 weeks of weight training with or without peanut protein supplementation in older adult men and women.
- Trial name
- NCT04015479
- Testing
- Peanut Protein Powder, Full body resistance training
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Auburn University
T2D, Blood Pressure
Potatoes, Type 2 Diabetes, and Cardiometabolic Health
Type 2 diabetes (T2D) is a major chronic health condition which increases risk of coronary artery disease, frailty, cognitive decline, and mortality.
- Conditions
- T2D, Blood Pressure, Cardiometabolic Health
- Trial name
- NCT07229482
- Testing
- Controlled diet: Potato-rich healthy dietary pattern, Controlled diet: Typical Western-style dietary pattern
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Rotavirus Infection, Vaccine Response Impaired
The Effects of Increased Inoculum on Oral Rotavirus Vaccine Take and Immunogenicity
Rotavirus is the leading cause of diarrhea in children worldwide. Oral rotavirus vaccines work remarkably well in high-income countries, but for unclear reasons they underperform in low-income countries.
- Conditions
- Rotavirus Infection, Vaccine Response Impaired, Vaccine Virus Shedding
- Trial name
- NCT02992197
- Testing
- Rotarix, dose 1, Rotarix, dose 2
- Where
- Bangladesh
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Augmented Reality Exercise Program, Traditional Exercise Program
Effects of an Augmented Reality Exercise Program in Older Adults
This research aims to examine the effects of an augmented reality (AR) exercise program on physical fitness (cardiorespiratory capacity, strength, balance, agility, and flexibility) and cognitive function (reaction time…
- Conditions
- Augmented Reality Exercise Program, Traditional Exercise Program, Control Group
- Trial name
- NCT06549140
- Testing
- Augmented reality exercise program, Traditional exercise program
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade da Madeira
Emotional Processing, Mood
Combined Blood Pressure Medication and Activity Scheduling for Low Mood
This study explores the effects of 7-day losartan (50mg) versus placebo with brief behavioural activation on emotional processing in young volunteers low in positive mood
- Trial name
- NCT07017023
- Testing
- Losartan with BA
- Where
- United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Surgical Education
Effect of Artificial Intelligence-Augmented Human Instruction on Surgical Simulation Performance
At the Neurosurgical Simulation and Artificial Intelligence Learning Centre, we seek to provide surgical trainees with innovative technologies that allow them to improve their surgical technical skills in risk-free environments…
- Trial name
- NCT06273579
- Testing
- Expert instruction using AI tutor script, AI-augmented personalized expert instruction
- Where
- Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- McGill University