Clinical trials: Effect Increased
Cardiovascular Diseases, Type 2 Diabetes Mellitus
A Series of Pilot Studies to Evaluate the haemoDynamic and mEtabolic Effects oF apelIn aNd rElaxin
Type two diabetes mellitus (T2DM) is a common, long term metabolic disorder characterised by hyperglycaemia (high blood glucose) resulting from insulin resistance and relative insulin insufficiency.
- Trial name
- DEFINE (NCT03449251)
- Testing
- Apelin, Relaxin, Normal saline
- Where
- United Kingdom
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Premature Infant
Effect of Increased Enteral Protein on Body Composition of Preterm Infants
The study hypothesis is that, in human milk-fed extremely preterm infants, higher protein intake compared to usual protein intake reduces percent body fat (%BF) at 3 months of age.
- Trial name
- NCT03586102
- Testing
- High protein supplementation, Standard protein supplementation
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Alabama at Birmingham
Sports Physical Therapy
WB-EMS Increase Energy Expenditure at Rest and During Uphill Walking Exercise
Whole-body electrical stimulation (WB-EMS) has become increasingly popular as a tool to provide additional benefits compared to conventional exercise.
- Trial name
- NCT05218512
- Testing
- WB-EMS
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Vocal Cord Paralysis, Recurrent Laryngeal Nerve
Effect of IONM on Efficacy and Safety Using Sugammadex in Thyroid Surgery
Thyroidectomy is a frequently performed surgeon by the head and neck and endocrine surgeons. In recent years, surgical techniques and technological developments have resulted in a significant reduction in complication rates.
- Trial name
- NCT03634956
- Testing
- Group B. Sugammadex sodium-IONM
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Pulmonary Heart Disease
A Study of Commercial DEFINITY® to Monitor the Effects of the Heart's Pulmonary Artery Pressure
The purpose of this clinical research is to learn if DEFINITY® 416 will cause any adverse effects during Right Heart Catheterization. This research was requested by the FDA.
- Trial name
- NCT00918866
- Testing
- Definity
- Where
- 8 sites in United States
- Volunteers
- 32 people
- Sponsor
- Lantheus Medical Imaging
Short Bowel Syndrome
Effect of the Enteric Hormone Glucagon-Like Peptide (GLP-2) on the Intestinal Blood Flow in Patients With Short Bowel Syndrome
The aim of the study is to investigate the effect of the enteric hormone Glucagon-like Peptide (GLP-2) on patients with short bowel syndrome
- Trial name
- NCT00673751
- Testing
- GLP-2
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Impaired Glucose Tolerance, Type 2 Diabetes
Effect of Increased Intake of Low Fat Dairy Products on Weight Loss and Insulin Resistance
The purpose of this study is to determine if increased intake of low-fat milk products and calcium as part of a calorie restricted diet helps achieve a healthier body weight and body composition and decrease blood glucose levels…
- Conditions
- Impaired Glucose Tolerance, Type 2 Diabetes, Metabolic Syndrome
- Trial name
- NCT00564551
- Testing
- High dairy and calcium intake, Usual intake
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- University of Calgary
Stroke
The Effects of an Augmented Reality-Based Mirror Therapy System in Patients With Stroke
Objective The aim of this study is to investigate the effects of an augmented reality-based mirror therapy system (MirrARm), developed using sensor-based tracking and visual feedback principles, on upper extremity motor recovery…
- Trial name
- NCT07533734
- Testing
- Augmented Reality-Based Mirror Therapy, Conventional Mirror Therapy, Conventional Physiotherapy Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Marmara University
Type 2 Diabetes Mellitus
Bexagliflozin Efficacy and Safety Trial
The purpose of this study is to investigate the effect of bexagliflozin in lowering hemoglobin A1c (HbA1c) levels in patients with type 2 diabetes mellitus (T2DM) and increased risk of cardiovascular adverse events.
- Trial name
- BEST (NCT02558296)
- Testing
- Bexagliflozin
- Where
- 157 sites in United States, Canada and 8 more
- Volunteers
- 1,700 people
- Sponsor
- Theracos
Polycystic Ovary Syndrome
Effect of Increased Circulating Androgens on Granulosa Cell Responses to FSH.
The purpose of this study is to evaluate the effect of increased circulating androgens on estradiol production by the granulosa cells in response to FSH stimulus.
- Trial name
- NCT02389088
- Testing
- Letrozole
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Augmented Reality
AR vs In Person Simulation for Medical Workplace Training
This study will evaluate the physiologic and emotional effects of an augmented reality (AR) simulation versus an in-person simulation. This is a single institution, non-inferiority, randomized controlled trial.
- Trial name
- NCT05674188
- Testing
- Augmented Reality Headset
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Stanford University
Performance Enhancement, Athlete
Augmented Feedback Effects on Shoulder Rotator Performance
The existing literature demonstrates that motor learning strategies are effective in enhancing sports performance. One of these strategies, augmented feedback, is widely used in athletic training to help athletes achieve their…
- Conditions
- Performance Enhancement, Athlete, Shoulder
- Trial name
- NCT07510893
- Testing
- Augmented Feedback
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Elif Turgut
Second Stage of Labor
Searching for the Perfect Oil to Protect the Perineum: A Randomized-Controlled, Double-Blind Trial
In this study we intend to randomly assign each parturient one of two commonly used oils to be applied during the second stage of labor, one of them containing vitamin E.
- Trial name
- NCT00662974
- Testing
- perineal massage with Wheat Germ Oil during the second stage of labor, perineal massage with almond oil during the second stage of labor
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Ischemic Stroke
Effect of Adding Augmented Cues /Hand Stroke Patient
This study aims to investigate the effect of adding augmented cues to conventional physical therapy intervention on hand function in patients with post-stroke hemiparesis.
- Trial name
- AUGMENTED CUES (NCT07654582)
- Testing
- Conventional physical therapy, musicgloves training
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Lipoprotein Disorder Disease
Safety and Tolerance of Increased Doses of HRS-5346 Tablets in Healthy Subjects
This is a randomized, double-blind, placebo-controlled phase I clinical study. The primary objective is to evaluate the safety, tolerability, PK, and PD of single- and multiple-dose HRS-5346 in healthy subjects, and to evaluate…
- Trial name
- NCT06441227
- Testing
- HRS-5346 tablets
- Where
- China
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.
Multiple Sclerosis
The Effect of Augmented Reality Based Telerehabilitation Application on Neuromuscular and Sensorimotor Parameters in Multiple Sclerosis Patients
Core stability, which is affected from the early period in with patients Multiple Sclerosis (PwMS), is due to deterioration in the somatosensory, motor and musculoskeletal systems.
- Trial name
- NCT05639517
- Testing
- Augmented Reality Based Telerehabilitation Application, Training face-to-face
- Volunteers
- 30 people
- Sponsor
- Ankara Yildirim Beyazıt University
Cancer and Chemotherapy Related Anemia, Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma)
Augmented Virtual Reality for Reducing Pain, Stress, Anxiety and Improve Self Efficacy in Adult Cancer Patients Undergoing Chemotherapy in The West Bank
The main purpose of this study is to examine the effect of using AVR on pain, stress, anxiety, and SE among adult cancer patients undergoing chemotherapy in the West Bank hospitals in Palestine.
- Trial name
- AVR-CHEMO (NCT07152938)
- Testing
- AVR Group (Chemotherapy + AVR)
- Where
- 3 sites in Palestinian Territories
- Volunteers
- 150 people
- Sponsor
- Arab American University (Palestine)
Eating Behavior, Obesity
Effect of Gut-Cued Eating on BMI and Efficacy of Open-Label Placebo to Augment Weight Loss
The study will assess the effect of attending to stomach-cues of hunger and fullness on body weight and any additional benefit provided by open-label placebo.
- Conditions
- Eating Behavior, Obesity, Body Weight, Hunger
- Trial name
- GCE (NCT03850990)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Effect Increased, Safety Issues
Bronchoscopic Microwave Intervention Treatment in Advanced Central NSCLC
A randomized, prospective study of the efficacy and safety of the first-line treatment in advanced central non-small cell lung cancer patients by anti-PD-1 / PD-L1 monoclonal antibody and chemotherapy versus anti-PD-1 / PD-L1…
- Trial name
- NCT04360655
- Testing
- bronchoscopic microwave intervention, anti-PD-1 / PD-L1 monoclonal antibody and chemotherapy
- Volunteers
- 50 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Postprandial Glucose Homeostasis
The Effect of an Acute Increase in Plasma IL-6 on Glucose Tolerance When a Meal is Administered Intraduodenally
The aim of the study is to investigate and clarify whether the effect of IL-6 on glucose tolerance and insulin secretion are secondary to the changes in gastric emptying.
- Trial name
- DUIL-6 (NCT03660332)
- Testing
- Infusion of a liquid meal intraduodenally
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet