Clinical trials: Effects, Longterm
Carpal Tunnel Syndrome
Platelet Rich Plasma and Perineural Injection Therapy for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT02696161
- Testing
- platelet rich plasma, 5% dextrose
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Congenital Heart Disease
Fontan Circulation and Cardiopulmonary Function: Prognostic Factors, Hemodynamics and Long-term Effects
Cross-sectional study of a national cohort of adolescents with univentricular congenital heart defects and Fontan type palliation.
- Trial name
- NCT02378857
- Where
- Norway
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cerebral Palsy, Hyperbaric Oxygen Therapy
Effect of Hyperbaric Oxygen Therapy on Cerebral Palsy
Abnormal gait is a common issue in children with CP. As a result of motor weakness and a lack of voluntary motor control. Furthermore, gait in children with cerebral palsy is characterized by a slower walking speed, a shorter…
- Trial name
- NCT05136716
- Testing
- Traditional Physical Therapy, Hyperbaric oxygen therapy
- Where
- Saudi Arabia
- Volunteers
- 39 people
- Sponsor
- Batterjee Medical College
Chronic Obstructive Pulmonary Disease
Long Term Effect of an Education and Training Program for Patients With Chronic Obstructive Pulmonary Disease
A parallell group study comparing the effect of an education program with an education and training program for patients with COPD. 30 participants in each group. Participants self-select which group they wanted to be in.
- Trial name
- NCT00159549
- Testing
- education and training program
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Norwegian University of Science and Technology
Leukemia, Long-term Effects Secondary to Cancer Therapy in Children
Neurobehavioral Complications in Children Who Were Previously Treated With Steroids and Intrathecal Therapy for Acute Lymphoblastic Leukemia
RATIONALE: Cancer therapies may affect the ability of a child's brain and central nervous system to function normally. Learning to identify which patients will develop complications may improve the ability of doctors to plan…
- Conditions
- Leukemia, Long-term Effects Secondary to Cancer Therapy in Children, Neurotoxicity, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- NCT00085176
- Testing
- management of therapy complications, psychosocial assessment and care
- Where
- 31 sites in United States
- Volunteers
- 286 people
- Sponsor
- Children's Oncology Group
Anterior Cruciate Ligament Reconstruction
Neurophysiologic Correlates of Movement Planning During Complex Jump Landing Tasks and the Role of Cognitive Function
To examine the long-term effects of anterior cruciate ligament injuries and reconstructions (after successful rehabilitation) on cortical processes of motor planning during complex jump landing tasks and the relevance of…
- Trial name
- NCT03336060
- Testing
- Cortical Correlates of Jump Landing Task
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Goethe University
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Evaluation of Symptom-specific Goal Achievement
Lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) consists of a constellation of symptoms (including voiding, storage, and post-micturition).
- Trial name
- NCT00836823
- Testing
- Alfuzosin
- Where
- 2 sites in South Korea
- Volunteers
- 130 people
- Sponsor
- Samsung Medical Center
Chronic Graft vs Host Disease
Predictive Biomarkers For Pediatric Chronic Graft-Versus-Host Disease
Chronic graft-versus-host disease (cGVHD) can be hard to diagnose, difficult to manage and contributes significantly to morbidity and mortality in hematopoietic stem cell transplantation patients.
- Trial name
- ABLE-cGVHD (NCT02067832)
- Where
- 25 sites in United States, Austria and 1 more
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Gestational Diabetes Mellitus (GDM), Non-communicable Chronic Diseases
Long-term Evaluation of Gestational Endocrine & Metabolic Dynamics
Gestational diabetes mellitus (GDM) is the most common complication and metabolic disorder during pregnancy, with clear risks to both the mother and fetus.
- Trial name
- LEGEND (NCT07119177)
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Yang ZHANG
Oxidative Stress, Muscle Strength
The Long-term Effects of Oceanix™ on Resistance Training Adaptations
This study will examine the effects of Oceanix™, an antioxidant supplement, on muscle performance, immune and endocrine function, recovery and safety in participants undergoing resistance training.
- Conditions
- Oxidative Stress, Muscle Strength, Resistance Training, Body Composition
- Trial name
- NCT04136821
- Testing
- Oceanix, Resistance Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Attention Deficit Hyperactivity Disorder, Transcranial Direct Current Stimulation
Clinical Efficacy and Long Term Effects of Transcranial Direct Current Stimulation (tDCS) in Children With Attention Deficit/Hyperactivity Disorder (ADHD)
Attention-Deficit/Hyperactivity Disorder (ADHD) is the most commonly diagnosed neurodevelopmental disorder in childhood. Patients with ADHD present inattention, impulsivity and hyperactivity causing severe impairments on academic…
- Trial name
- STIMADHD (NCT04704687)
- Testing
- Transcranial Direct Current Stimulation
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
General Anesthetics Toxicity
Anesthesia Neurodevelopmental Impact in Congenital Scoliosis Children
In the past, a large number of animal studies have suggested that anesthesia exposure has potential neurotoxic effects, resulting in persistent cognitive and behavioral deficits.
- Trial name
- NCT06315933
- Testing
- General anesthesia
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking Union Medical College Hospital
Metabolic Health
Effects of Exercise During Pregnancy on the Long-term Metabolic Health of Mothers and Their Offspring
The aim of this study was to assess the long-term metabolic effects of gestational exercise on overweight and obese women and their offspring 8-10 years post-intervention.
- Trial name
- NCT07435857
- Testing
- exercise
- Where
- China
- Volunteers
- 221 people
- Sponsor
- Peking University First Hospital
Diabetes Type 2
The Short and Long-term Effects of Low Advanced Glycation End Product* Diet
The aim of this study was to examine the hypothesis that a diet low in advanced glycation end products (AGE) would provide short and long term improvement in metabolic and inflammatory parameters and serum AGE, Srage…
- Trial name
- AGE (NCT06005519)
- Testing
- low AGE diet education
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Disorder of Consciousness
Long-term Effect of tDCS in Patients With Disorders of Consciousness
In this multicentric double-blind sham controlled study, the investigators plan to assess the effects of 20 sessions of tDCS on long-term behavioral recovery in patients with disorders of consciousness.
- Trial name
- NCT03114397
- Testing
- transcranial direct current stimulation - active
- Where
- Belgium
- Volunteers
- 62 people
- Sponsor
- University of Liege
Lymphoma, Follicular
A Study of Long-Term Rituximab (MabThera) Maintenance Therapy in Participants With Advanced Follicular Lymphoma
This study will evaluate the efficacy, safety, and tolerability of long-term maintenance therapy with rituximab in participants with advanced follicular lymphoma who have had a positive response to first-line treatment with a…
- Trial name
- NCT02569996
- Testing
- Rituximab
- Where
- 21 sites in Hungary
- Volunteers
- 124 people
- Sponsor
- Hoffmann-La Roche
Asthma
Asthma and Osteopathic Manipulative Treatment
The effect of Osteopathic Manipulative Treatment (OMT) has been studied in adult patients with chronic obstructive pulmonary disease (COPD) and children with asthma, however, to the authors' knowledge, no current studies have…
- Trial name
- NCT03864354
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Des Moines University
Knee Osteoarthritis
The Combination Effect of Platelet-rich Plasma and Hyaluronic Acid for Knee Osteoarthritis
Although platelet rich plasma (PRP) and Hyaluronic acid (HA) are beneficial for osteoarthritis of knee (OA knee), the combined effect of PRP with HA was not clear so far.
- Trial name
- NCT03290365
- Testing
- platelet rich plasma + Hyaluronic acid, platelet rich plasma + normal saline
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Type 1 Diabetes
Long Term Effects of Diabetes of Very Young Children
To investigate neurocognitive and behavioral measures in 25 children aged 6-10 years diagnosed with diabetes for > 5 years who have received long-term insulin pump therapy (> 3 years) compared to a group of children matched for…
- Trial name
- NCT00707629
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Indiana University
Long-term Effects of Thymosin Alpha 1 Treatment
Long-term Prognosis of Patients With Sepsis After Immunotherapy
Current clinical studies of thymosin α1 for sepsis have focused on short-term outcomes (28-day or 90-day mortality), and lack of clinical data on long-term outcomes (3 year mortality) of patients with sepsis after immunotherapy.
- Trial name
- NCT04901104
- Testing
- Thymosin Alpha1
- Volunteers
- 900 people
- Sponsor
- Sun Yat-sen University