Clinical trials: Embryo
Oocyte Competence
Modulation Contrast Microscopy Imaging for Oocyte Quality Assessment
The present study aims to describe novel non-invasive parameters related to the competence of female reproductive cells (oocytes).
- Trial name
- NCT03683290
- Testing
- Image acquisition and analysis
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Center for Reproductive an Genetic Health
Infertility, Assisted Reproductive Technology
Does the Embryo Transfer Technique Affect the Success of in Vitro Fertilization?
Prospective, open, randomized, parallel, two-arm trial to compare the clinical pregnancy rate between most commonly used two embryo transfer techniques: trial followed by transfer technique and afterloading technique
- Conditions
- Infertility, Assisted Reproductive Technology, IVF
- Trial name
- NCT03756857
- Testing
- Afterload Transfer, Trial followed by transfer
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Acibadem Kadiköy Hospital
Anxiety, Assisted Reproductive Treatments
Virtual Reality for Anxiety Relief in Infertile Women
This study examines the impact of virtual reality (VR) applications on anxiety levels before and after embryo transfer procedures.
- Conditions
- Anxiety, Assisted Reproductive Treatments, Women, VR
- Trial name
- NCT07020975
- Testing
- VR Glasses
- Where
- Cyprus
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cyprus Aydin University
Clinical Pregnancy, Embryo Implantation
DNA Amplification in Blastocoel Fluid
Introduction: Although innovative procedural changes in frozen embryo transfer (FET) cycles have increased the implantation rate of blastocysts transferred significantly, blastocyst selection remains a significant limiting factor…
- Trial name
- NCT04744844
- Testing
- blastocoel fluid biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Antalya IVF
GnRH Antagonist IVF Protocol, Fresh Embryo Transfer
GnRH for Luteal Support - Mechanism of Action
This prospective observational study will include women undergoing IVF treatment with a GnRH antagonist protocol and fresh embryo transfer at the IVF unit of Shaare Zedek Medical Center.
- Conditions
- GnRH Antagonist IVF Protocol, Fresh Embryo Transfer, Administration of Hormonal Luteal Support
- Trial name
- NCT07620067
- Testing
- GnRH agonist, Progesterone
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Heli Alexandroni
Control Media Only, Study hCG and Media
Intrauterine Human Chorionic Gonadotropin at the Time of Embryo Transfer
Techniques to improve pregnancy and delivery rates in IVF cycles have focused not only on the embryos transferred, but also the conditions in the uterus at the time of transfer and implantation.
- Trial name
- NCT01643993
- Testing
- hCG at the Time of Embryo Transfer, Control
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility (IVF Patients), Clinical Pregnancy After Single Embryo Transfer
Correlation Of Clinical Outcomes After Transfer Of Good-Quality Morphology Embryos In Patients With A Favorable Prognosis And Non-Invasive Preimplantation Genetic Testing For Aneuploidy (NiPGT-A) Results
Non-invasive preimplantation genetic testing for aneuploidy (NiPGT-A) is an emerging approach that analyzes embryonic cell-free DNA (cfDNA) released into the spent culture medium (SCM) to assess chromosomal status without…
- Conditions
- Infertility (IVF Patients), Clinical Pregnancy After Single Embryo Transfer, Embryo Diagnosis and Selection
- Trial name
- NCT07700602
- Where
- Vietnam
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Fertility
TiLE (Time Lapse Eeva) Clinical Trial
The purpose of the study was to explore the added value of adjunctive use of Early Embryo Viability Assessment (Eeva) with morphological grading in identifying optimal embryos for transfer.
- Trial name
- TiLE (NCT02417441)
- Testing
- Eeva
- Where
- 23 sites in Canada, Denmark and 7 more
- Volunteers
- 976 people, healthy volunteers welcome
- Sponsor
- Merck KGaA, Darmstadt, Germany
Infertility
Injection of Hormone to Enhance Implantation in Embryo Transfer After IVF
The endometrium is deprived of signals form the embryo in IVF conditions. Studies suggest that placing HCG into the uterus prior to embryo transfer can enhance implantation.
- Trial name
- NCT01986374
- Testing
- HCG is introduced
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Servy Massey Fertility Insititute
Embryo Development
Effect of Abstinence Duration on Embryo Development
The aim the investigators study is to analyze the embryo development if oocytes of the participants are injected with sperm from a longer or shorter (2 hours) abstinence duration.
- Trial name
- NCT03323892
- Testing
- second masturbation
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility
Comparing Intra-vaginal Culture of Embryos to In-vitro Culture of Embryos With Minimal Stimulation
The purpose of this study is to evaluate implantation rate with intra-vaginal culture (IVC) with the INVOcell device versus traditional In-Vitro Fertilization (IVF) while using minimal stimulation protocols
- Trial name
- NCT02802176
- Testing
- INVOcell device, Traditional IVF
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Infertility, Female
Comparison of in Vitro Fertilization Rates of Oocytes and Embryo Development Using Two Techniques of Semen Processing
The investigators propose to assess one method of sperm selection based on the characteristics of spermatozoa recently introduced: Sperm Selection Assay, which used a gradient of concentration of progesterone to act as…
- Trial name
- NCT03186170
- Testing
- SSA sperm selection
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Infertility Low Over Reserve, IVF
BPA Levels Relationship With IVF/ICSI Outcomes in Low Ovarian Reserve
The relationship between BPA elevation in urine, blood, and follicle fluid and embryo quality, IVF/ICSI outcomes.
- Conditions
- Infertility Low Over Reserve, IVF, Infertility, Female
- Trial name
- NCT04654598
- Testing
- BPA levels
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Nefise Nazlı YENIGUL
Infertility
Comparison of Transfers of Fresh and Thawed Embryos in High Responder Patients
This study tests the hypothesis that controlled ovarian stimulation impairs endometrial receptivity in high responders.
- Trial name
- NCT00963079
- Testing
- Embryo cryopreservation, Fresh blastocyst transfer
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fertility Center of Las Vegas
Spontaneous Abortion, Fetal Death
Environmental Factors and Embryonic Development Project
The Environmental Factors and Embryonic Development Project was set up to investigate environmental exposures and behavioral factors responsible for embryonic dysplasia and gestational complications in pregnant women.
- Conditions
- Spontaneous Abortion, Fetal Death, Stillbirth, Birth Defects
- Trial name
- EFED (NCT04182503)
- Testing
- No intervention
- Where
- 19 sites in China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Infertility, Female
Success Rate Natural Cycles Versus Modified Natural Cycles in Frozen Embryos
There has been a recent significant increase in the frozen embryo replacement (FER) cycles due to freeze-all cycles to decrease the risk of ovarian hyperstimulation syndrome.
- Trial name
- NCT03798886
- Testing
- natural cycle, modified natural cycle, embryo transfer
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Fertility
The Influence of Different Concentrations of Glucose in Culture Media on Fertilization and Embryo Quality
The aim of this study is to examine whether incubation of human oocytes until pronuclear stage, in different culture media containing high and low concentrations of glucose affect fertilization differently, not only in standard…
- Trial name
- NCT00606073
- Testing
- Universal IVF Medium + ISM1 Medium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Infertility, Pregnancy, Multiple
Correlation Between Oocyte and Embryo Mechanical Properties on Embryo Development and Clinical Pregnancy After In Vitro Fertilization
The purpose of this study is to determine whether oocyte and embryo mechanical properties measured during in vitro fertilization can predict embryo development outcomes and clinical pregnancy.
- Trial name
- EMECH (NCT02530892)
- Testing
- EmbryoHug
- Where
- 3 sites in United States, China and 1 more
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Stanford University
Infertility, Reproductive Issues
Impact of a Predetermined Day 5 ET vs. a Predetermined Day 6 ET on Clinical Pregnancy Rate After ICSI Treatment
The aim of this prospective multicenter study is to investigate the influence of a predetermined embryo transfer on day 6 compared to a predetermined embryo transfer on day 5.
- Trial name
- NCT06447077
- Where
- Germany
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Infertility Treatment Center Dortmund
Pregnancy
Down-regulated Hormonally Controlled Cycles for Vitrification-warmed Blastocyst Transfers
Currently all patients that have freeze-all ICSI treatment cycles have the start of their FET cycle scheduled with the use of OCP.
- Trial name
- NCT02238431
- Testing
- Lucrin depot, OCP, Natural
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Antalya IVF