Clinical trials: Endoscopic Suturing
Colon Malignant Tumor, Colon Benign Tumor
Apollo Overstitch, a Treat and Resect Model
The Overstitch (Apollo Endosurgery, Austin, Texas) is an FDA cleared product which attaches to a standard double channel endoscope.
- Trial name
- Overstitch (NCT01307813)
- Testing
- Overstitch Endoscopic Suturing System
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Surgery
Endoscopic Suturing (ES) Registry
To determine patient outcomes (survival, additional endoscopic or surgical procedures) with an endoscopic suturing technique at predetermined intervals compared to historical controls when applicable.
- Trial name
- NCT03776188
- Where
- 11 sites in United States
- Volunteers
- 204 people
- Sponsor
- American Gastroenterological Association
Endoscopic Tissue Apposition, Endoscopic Suturing
Prospective Evaluation of the Efficacy and Safety of Endoscopic Tissue Apposition
This study is a prospective registry of patients undergoing endoscopic suturing and/or clip placement at our institution to assess the efficacy and safety of endoscopic tissue apposition.
- Conditions
- Endoscopic Tissue Apposition, Endoscopic Suturing, Endoscopic Clipping, Bariatric Endoscopy
- Trial name
- NCT03626194
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Colorado, Denver
Obesity
Endomina Controlled Study
The aim of this trial is to evaluate the efficacy of an endoluminal vertical gastroplasty (EVG) using an endoluminal-suturing device.
- Trial name
- NCT03255005
- Testing
- Endomina, Diet
- Where
- 2 sites in Belgium, France
- Volunteers
- 72 people
- Sponsor
- Erasme University Hospital
ESD Defect, Gastric Epithelial Lesion
Su2ura ESD Closure Pilot Study
This study is a single-center, prospective, single-arm, non-blinded first-in-human (FIH) early feasibility study intended to evaluate the short-term safety and technical feasibility of closure of gastric post-ESD defects using a…
- Trial name
- NCT07843719
- Testing
- Su2ura® GI system
- Volunteers
- 5 people
- Sponsor
- Chinese University of Hong Kong
Postoperative, Anastomosis, Surgical
Closure of Anastomotic Leaks in the Stomach and Esophagus by Endoscopic Suturing
Patients with suspected leakage at the specified surgical anastomoses undergo an immediate diagnostic endoscopy as part of current clinical routine.
- Trial name
- GASTROSUTURE (NCT01139424)
- Testing
- endoscopic suturing
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Schleswig-Holstein
Esophageal Stenosis, Stent Migration
Optimal Endoscopic Suturing Pattern for Esophageal Stent Fixation
Researchers are trying to determine which suturing pattern for esophageal stent placement is more effective in a randomized fashion as currently what suturing pattern to use is an arbitrary decision.
- Conditions
- Esophageal Stenosis, Stent Migration, Suture, Complication
- Trial name
- NCT04007692
- Testing
- Esophageal stent placement
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Obesity
National Registry of Obesity Treatment by Endosleeve
Obesity and overweight have emerged as public health problems of a pandemic nature, significantly reducing the life expectancy of those affected.
- Trial name
- NCT06657339
- Testing
- Therapeutic endoscopy endosleeve using a gastric suturing device (OverStitch™/Endomina™)
- Volunteers
- 354 people
- Sponsor
- Société Française d'Endoscopie Digestive
Cranial Sutures; Closure
Role of Leukocyte- and Platelet-Rich Fibrin Membranes in Endoscopic Endonasal Skull Base Reconstruction
Prospective investigation of the effectivity of L-PRF membranes for skull base reconstruction after endoscopic endonasal skull base surgery (transsphenoidal) versus classical closure techniques.
- Trial name
- NCT03910374
- Testing
- Dural closure
- Where
- 3 sites in Belgium, Spain
- Volunteers
- 220 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obesity, Primary
A Feasibility Study for the Treatment of Primary Obesity Cross-over Arm
Cross-over arm of the pilot study evaluating a treatment for obesity.
- Trial name
- NCT05939973
- Testing
- g-Cath EZ Delivery Catheter with Snowshoe Suture Anchors
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- USGI Medical
Obesity, Body Weight
Endoscopic Suturing for Primary Obesity Treatment
Gastric restriction is an important principle of both roux-en-Y gastric bypass and laparoscopic adjustable gastric banding. The FDA cleared OverStitch Endoscopic Suturing System (Apollo Endosurgery, Austin, TX) offers the…
- Conditions
- Obesity, Body Weight, Overweight
- Trial name
- PROMISE (NCT01662024)
- Testing
- Endoscopic gastric restrictive procedure
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Oesophageal Disease
Endomina Diverticulum
Esophageal diverticulum is a rare disease. Majority comes form the pharyngo-esophageal junction (70 % Zenker's Diverticulum), 10% are mediothoracic and 20% epiphrenic.
- Trial name
- NCT03609073
- Testing
- Endomina
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- Erasme University Hospital
Obesity, Over Weight
Endoscopic Suturing of the Gastric Pylorus to Delay Gastric Emptying and Treat Obesity
The purpose of this study is to demonstrate the efficacy and safety of endoscopic suturing of the gastric pylorus to delay gastric emptying and treat obesity.
- Trial name
- NCT02191501
- Testing
- Pyloric restriction
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Northwell Health
Obesity
Clinical Trial for Weight Regain Post-RYGB: APC Versus APC Plus Endoscopic Suture Technique
Obesity is a worldwide health and sociopolitical problem. Excessive body-weight currently affects over 50% of the Brazilian population. It has been well established that obesity is an independent health risk.
- Trial name
- NCT03094936
- Testing
- APC, Endoscopic Suture Technique (OverStitch TM)
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Obesity
A Feasibility Study for the Treatment of Primary Obesity
This study has been expanded to a four center, open-label, 2-group randomized pilot study evaluating a treatment for obesity.
- Trial name
- NCT03837691
- Testing
- Placement of Snowshoe Suture Anchors, Moderate Intensity Diet & Exercise Program
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- USGI Medical
Colorectal Neoplasms
An Endoscopic Barbed-clips Suturing for Colorectal ESD
Endoscopic submucosal dissection (ESD) was developed to allow en bloc resection of colorectal neoplasm. Although colorectal ESD has been widely accepted as a minimally invasive treatment option for early colorectal neoplasm…
- Trial name
- NCT05045911
- Testing
- Endoscopic Barbed-clips Suturing
- Where
- 2 sites in China
- Volunteers
- 35 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Endoscopic Surgical Procedures
Endoscopic Hand Suturing in the Prevention of Gastrointestinal Bleeding After Gastric Endoscopic Submucosal Dissection.
Endoscopic hand-suturing (EHS) is a significant improvement in gastrointestinal advanced endoscopic procedures. Evidence supporting its effectiveness in clinical practice is limited due to its recent introduction and limited…
- Trial name
- NCT06779266
- Testing
- Suturing, Clipping, No closure
- Where
- Poland
- Volunteers
- 179 people
- Sponsor
- Jagiellonian University
Nasal Obstruction
Comparison of a Septal Stapler to Suture Closure in Nasal Septoplasty
The primary objective of this study is to determine if there is a time savings in the operating room by using a septal stapler instead of suture in closure of primary septoplasty.
- Trial name
- NCT01541839
- Testing
- Septal Stapler
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Alberta
Obesity, Mild
EGPSS for Weight Management in an in Vivo Human Model
ndoscopic bariatric and metabolic therapies (EBMTs) have introduced more convenient, minimally invasive, and safe approaches to weight management.
- Trial name
- NCT07186959
- Testing
- endoscopic gastric purse-string suturing
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Liu Yan
Obesity
Safety and Feasibility of an Endoluminal-suturing Device (Endomina TM) for Gastric Reduction
Objectives: Study to evaluate safety and feasibility of an endoluminal vertical gastroplasty (EVG) using an endoluminal-suturing device.
- Trial name
- NCT02534662
- Testing
- ENDOMINA
- Where
- Belgium
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Theodor Bilharz Research Institute