Clinical trials: Family Research, active
Family History of Pancreas Cancer
Prospective Familial Registry for Pancreas Research
The purpose of this research is to develop a resource registry of individuals currently without pancreatic cancer but are members of a kindred with two or more blood-related family members with pancreas cancer.
- Trial name
- PARTNER (NCT07358208)
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Psychiatric Problem, Child Neglect
Implementing Dyadic Developmental Psychotherapy (DDP) - Evaluation Research
The objective of this study is to evaluate the implementation and use of Dyadic Developmental Psychotherapy (DDP) in three centra, with particular focus on its potential effects on the quality of the observable caregiver-child…
- Conditions
- Psychiatric Problem, Child Neglect, Maltreatment, Child Behavior Problem
- Trial name
- NCT04763720
- Testing
- Dyadic Developmental Psychotherapy
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Sykehuset Telemark
Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction
Optimizing Research With Diverse Families - Feasibility and Acceptability Study (FAST)
Evaluate feasibility and acceptability of recruiting Black and Hispanic families for an open label clinical trial of multinutrients while collecting real-time parent-reported child behavior data and collecting at-home…
- Conditions
- Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction, Irritable Mood
- Trial name
- FAST (NCT06133231)
- Testing
- Multinutrients; a 36-ingredient blend of vitamins, minerals, amino acids, and antioxidants
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Oregon Health and Science University
Nephronophthisis, NPH1
Research of Therapeutic Targets in the Frame of Nephronophthisis and Renal Associated Ciliopathies
Nephronophthisis (NPH) is an autosomal recessive, genetically heterogeneous disease, with mutations identified in over 20 genes (notably NPHP1 and NPHP4).
- Conditions
- Nephronophthisis, NPH1, Autosomal, Recessive
- Trial name
- NPH1 (NCT06648044)
- Testing
- Description: Research of therapeutic targets in the frame of nephronophthisis and renal associated ciliopathie
- Where
- France
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Imagine Institute
Consent Process
Examining the Efficacy of a Digital Media Intervention to Increase Recruitment Rates
WHEAT-Boost is a Study Within A Trial (SWAT) that aims to improve how families are recruited into neonatal research studies by testing a new way of sharing information.
- Trial name
- WHEAT-Boost (NCT07284329)
- Testing
- Intervention (Video) Arm
- Where
- 15 sites in Canada
- Volunteers
- 787 people
- Sponsor
- IWK Health Centre
Self-Help Devices, Long-Term Care
Assistive Device Rental/Purchase, LTC Service Use, and Caregiver Burden in Taiwan
The goal of this observational study is to examine the associations between assistive device approval and acquisition modality (rental or purchase), long-term care service utilization, and family caregiver burden among…
- Conditions
- Self-Help Devices, Long-Term Care, Caregiver Burden, Health Services Research
- Trial name
- NCT07782047
- Where
- Taiwan
- Volunteers
- 161,771 people
- Sponsor
- National Health Research Institutes, Taiwan
Patient Navigation
Empowering Families of Migrant Children and Youth with Special Healthcare Needs
The goal of this randomized controlled trial is to test if a patient navigator program improves healthcare experiences and outcomes for migrant families caring for a child or youth with special healthcare needs (i.e.
- Trial name
- MiNav (NCT06373588)
- Testing
- Patient Navigator
- Where
- 3 sites in Canada
- Volunteers
- 324 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Posttraumatic Stress Disorder
Resilient Roots: Supporting Youth and Families
Resilient Roots is integrated into the TRANSFORM Center to promote translation of research findings into clinical interventions, to inform the next generation of research on child abuse and neglect (CAN), and to facilitate…
- Trial name
- NCT06535516
- Testing
- Trauma-Focused Cognitive Behavioral Therapy (TF-CBT), Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) augmented with Socialization (S)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Diabetes, Chronic Disease
Families Implementing Good Health Traditions for Life
This study will provide evidence for the utility of using a community-engaged research approach to implement a tailored, family-oriented adaptation of the Diabetes Prevention Program that will have positive effects on risk…
- Conditions
- Diabetes, Chronic Disease, Type 2 Diabetes, Healthy Lifestyle
- Trial name
- FIGHT for Life (NCT07441655)
- Testing
- Families Implementing Good Health Traditions for Life
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Morehouse School of Medicine
Implementation Research
Implementation of Naturalistic Developmental Behavioral Intervention (NDBI) Through Coaching Caregivers of Young Autistic Children
Naturalistic developmental behavioral interventions (NDBIs) are a newer class of evidence-based interventions for young autistic children to promote their positive developmental or behavioral outcomes.
- Trial name
- NCT06923553
- Testing
- NDBIs
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas at Austin
Hearing Loss, Age-Related, Presbycusis
Optimizing Elderly Hearing Loss Care in Hong Kong A Cost-Effectiveness and Satisfactory Analysis of a Pilot Collaborative Model Between Otorhinolaryngologists and Family Medicine Specialists
This study will evaluate a new collaborative elderly hearing-loss service in Hong Kong. The service is based in Family Medicine (FM) and supported by Ear, Nose and Throat (ENT) specialist nurses and audiology services.
- Trial name
- NCT07782177
- Where
- Hong Kong
- Volunteers
- 500 people
- Sponsor
- Tseung Kwan O Hospital, Hong Kong
Ankylosing Spondylitis
Multi-omics Database for Integrative Microbiome Analysis in a Cohort of Korean Patients With Ankylosing Spondylitis
Multicenter Human Derivatives Prospective Cohort Study: Clinical information will be collected from patients with ankylosing spondylitis and their families who have provided research consent.
- Trial name
- NCT06076083
- Where
- 2 sites in South Korea
- Volunteers
- 600 people
- Sponsor
- Tae-Hwan Kim
Family Research
The PEARL-AGE Study. Multigenerational Gut Bacteria Transmission and Its Stability in Families.
Investigators will recruit up to 4-generations of human family cohorts, in order to characterize the microbiome and its changes across different generations.
- Trial name
- NCT05346016
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- Quadram Institute Bioscience
Weight Reduction, Prediabetes
Georgia CEAL RESTORES Family Diabetes Study
The goal of this clinical trial is to determine whether a family-based lifestyle intervention reduces the risk of type 2 diabetes (T2D) among parents and their children.
- Trial name
- GA CEAL (NCT07808723)
- Testing
- Family Diabetes Prevention
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Pancreatic Cancer, Thyroid Cancer
Integrated Cancer Repository for Cancer Research
The iCaRe2 is a multi-institutional resource created and maintained by the Fred \& Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer…
- Conditions
- Pancreatic Cancer, Thyroid Cancer, Lung Cancer, Esophageal Cancer
- Trial name
- iCaRe2 (NCT02012699)
- Where
- 42 sites in United States
- Volunteers
- 999,999 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Neoplasms, Hematologic Neoplasms
Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members
This study will collect biological samples for use in research experiments aimed at better understanding the clinical features of certain diseases.
- Conditions
- Neoplasms, Hematologic Neoplasms, Healthy Volunteers
- Trial name
- NCT00071045
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Mitochondrial NeuroGastroIntestinal Encephalopathy (MNGIE)
The Natural History Study of Mitochondrial NeuroGastroIntestinal Encephalopathy (MNGIE)
This is a multi-center natural history study of Mitochondrial NeurogastroIntestinal Encephalopathy (MNGIE). Patients will be followed over time to assess clinical symptoms.
- Trial name
- NAHIM (NCT01694953)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Columbia University
Healthy, Family Research
Pediatric Parenting Support in Flint
Public health disasters have disproportionate impacts on low income communities, through pathways that add to those of poverty and associated stressors, and act over extended periods.
- Trial name
- NCT03945552
- Testing
- Video Interaction Project
- Where
- 2 sites in United States
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Mental Health Wellness, Family Research
Health Without Barriers/Salud Sin Barreras
The goal of this study is to address a key health inequity - lack of community access to evidence-based programs to prevent chronic health conditions (e.g., Type 2 Diabetes) - by tailoring and delivering a family-based lifestyle…
- Conditions
- Mental Health Wellness, Family Research, Lifestyle Risk Reduction
- Trial name
- NCT06052943
- Testing
- Mindfulness-Based Intervention, Parent Education, Physical Activity
- Where
- 2 sites in United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Parkinson&Amp;#39;s Disease
A Study to Evaluate Efficacy, Safety and Tolerability of Hydroxychloroquine in Subjects With Parkinson's Disease
The purpose of this study is to determine if hydroxychloroquine is safe to take and whether there is potential for it to slow the progression of PD symptoms.
- Trial name
- NCT06816810
- Testing
- Hydroxychloroquine (HCQ)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Ottawa Hospital Research Institute